December, 2024

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A Look Back at the Affordable Care Act

Drug Topics

The Affordable Care Act was passed in 2010 to make health care and prescription medicine more accessible. Did it succeed?

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ASHP Midyear: Nearly Half of Adults With Epilepsy Use CBD Products

Pharmacy Times

Adults with epilepsy are underrepresented in most CBD trials, including common etiologies.

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CDC finds no evidence of bird flu virus in California toddler

STAT

Testing of samples taken from a child in California thought to have contracted H5N1 bird flu after drinking raw milk turned up no evidence of influenza viruses, the Centers for Disease Control and Prevention said Thursday.  A test run on a sample from the child — who went to a Marin County emergency department last week with a fever and vomiting — had been positive there for flu A.

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RFK Jr. could 'cost lives in this country' if he pursues changes to US vaccine policy, Gottlieb says

Fierce Pharma

Robert F. Kennedy Jr.’s appointment last month to lead the U.S. Department of Health and Human Services immediately sent waves of speculation swirling throughout the biopharma industry. | The former FDA Commissioner pointed to the threat of measles if vaccination rates were to decline by 5%.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Legislators urge DOJ to investigate PBMs for potential role in opioid epidemic

Fierce Healthcare

A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic. | A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic.

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Peculiar Articles: 10 Potential Conversation Starters From The Medical Literature

IDStewardship

In this posta list of peculiar journal articles are highlighted, which may serve as conversationstarters from the medical literature. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Social events like holiday parties or kids birthday parties can be unpredictable. Sometimes you know everyone and it is a lot of fun. Sometimes you do not know many people and you are stuck trying to make conversation with new acquaintances.

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ASHP: Identify and Counsel Patients at High Risk for Severe COVID-19

Pharmacy Times

By identifying patients at high risk for progressing to severe disease and counseling them on their treatment options, pharmacists empower patients to make informed decisions about their treatment.

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STAT+: AI versus AI: The emerging arms race over health insurance denials

STAT

Like many Americans, Holden Karau said she was fed up with health insurance. The software engineer’s disillusionment began in 2019, when her insurer, UnitedHealthcare, balked at covering physical therapy after she was hit by a car and could not walk. She said the hassles piled on stress, forced her to pay more out of pocket, and delayed access to care she needed to recover from multiple broken bones.

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FDA rejects J&J's subcutaneous Rybrevant filing and AZ's full approval bid for Andexxa

Fierce Pharma

Johnson & Johnson has received coal in its stocking from the FDA as manufacturing issues have tripped up the companys attempt to gain approval of its subcutaneous version of lung cancer drug R | The FDA has sent complete response letters to Johnson & Johnson and AstraZeneca, rejecting J&J's application for subcutaneous Rybrevant and AZ's bid for a full approval of Andexxa.

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Congress' end of year health deal may be falling apart

Fierce Healthcare

It still needs to pass, but an end-of-year package for healthcare is looking probable. The legislation includes PBM reform, telehealth extensions and more.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Five Lessons Learned About Antimicrobial Stewardship Metrics

IDStewardship

In this article an experienced antimicrobial stewardship pharmacist discusses lessons learned from navigating antimicrobial stewardship metrics. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article posted 13 December 2024 If you cannot measure it, you cannot determine if you have changedit. Antimicrobial stewardship metrics are essential for identifying, acting on, and re-evaluating opportunities to enhance the safe and appropriateuse of antibiotics.

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Cannabis Could Help Reduce Opioid Use in Patients with Chronic Pain

Drug Topics

Most patients with reduced opioid prescriptions during cannabis use had chronic musculoskeletal pain.

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Patients With Post-COVID POTS Experience Disruptions in Circadian Blood Pressure Rhythm Regulation

Pharmacy Times

Postural orthostatic tachycardia syndrome (POTS) diagnoses have greatly increased following the COVID-19 pandemic.

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Gilead to test once-a-year HIV prevention shot

STAT

Gilead said Tuesday that it will soon begin Phase 3 testing for a drug it believes could prevent HIV infection with just a single shot every year. Such a medicine, if proven effective, would be the closest thing to a vaccine the HIV field has produced in four decades of research. The company plans to begin the trial next year, with an eye toward regulatory filings in late 2027.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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UnitedHealthcare CEO Brian Thompson fatally shot in Manhattan: reports

Fierce Healthcare

UnitedHealth Group abruptly ended its investor day event on Wednesday morning as new reports surfaced that the CEO of its health plan division had been fatally shot. | UnitedHealth Group abruptly ended its investor day event on Wednesday morning as news reports surfaced that the CEO of its health plan division had been fatally shot.

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Reprieve for Chinese biotechs as BIOSECURE Act left out of key bill

Pharmaceutical Technology

Shares in WuXi AppTec, one of those implicated in the Chinese biotech blacklisting legislation, surged following the omission.

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Phase 3 Trial to Evaluate Molnupiravir for Treatment of COVID-19 in High-Risk Adults

Drug Topics

The MOVe-NOW study will assess the investigational oral antiviral using a different formulation than what is currently approved under an emergency use authorization.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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High-Dose Vitamin C Improves Outcomes for Late-Stage Pancreatic Cancer

Pharmacy Times

High-dose vitamin C, when combined with chemotherapy, has shown the potential to double the survival rate of patients with late-stage metastatic pancreatic cancer.

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STAT+: Ohio court sides with CVS, Walmart, and Walgreens in opioid case

STAT

The Ohio Supreme Court ruled that three of the largest pharmacy chain operators in the U.S. could not be held liable under a state nuisance law for contributing to the long-running opioid crisis. In a 5-to-2 vote, the court determined that the law barred two Ohio counties from obtaining a $650.9 million judgement that was won in a federal court against CVS Health, Walgreens, and Walmart.

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Deadline looms for post-Brexit label changes for UK meds

pharmaphorum

The MHRA has reminded pharma companies that from 1st January all medicines sold in the UK will have to comply with new labelling requirements

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Healthcare industry needs to get a grip on AI governance in 2025, ECRI warns

Fierce Healthcare

Risks with AI-enabled health technologies topped the list of the ECRI Institute's annual ranking of health technology hazards. | A well-known safety group debuted its annual report that lays out the top 10 health technology risks for the upcoming year. The risks of AI perpetuating bias or hallucinating answers to medical questions tops the list of risks for 2025.

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AstraZeneca scores FDA nod for Imfinzi as first immunotherapy for limited-stage small cell lung cancer

Fierce Pharma

AstraZeneca has picked off another label expansion for cancer blockbuster Imfinzi as the FDA has blessed it for limited-stage small cell lung cancer.

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PBM Reform Pulled Back in Late Change to Spending Package

Drug Topics

With pressure from the House GOP, expected PBM reform was not included in Congress end-of-year spending package.

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Familiarize Yourself With Updated Clinical Guidelines Recommendations for Restless Legs Syndrome

Pharmacy Times

Treatment for RLS includes lifestyle modifications, medication, and in some cases, non-drug therapies, aiming to reduce symptoms and improve sleep and daytime functioning.

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STAT+: Eli Lilly to test obesity medications as treatments for alcohol and drug addiction, CEO says

STAT

Eli Lilly, the company that makes the blockbuster weight loss treatment Zepbound, will start studying its obesity products as treatments for alcohol and drug abuse, making it the first major drugmaker to do so, CEO David Ricks said Tuesday. Emerging research suggests that GLP-1 drugs — Zepbound is one such treatment — not only reduce food cravings but may also suppress desires for other substances.

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What to know about Linzess and coffee

The Checkup by Singlecare

Tens of millions of people start their day with coffee without a second thoughtmany even find it difficult to have any thoughts at all before their first cup. But if youre taking prescription drugs on a regular basis, such as Linzess (the brand name for linaclotide), you may be wondering if you need to rethink your morning joe. Linzess is an oral medication that is approved by the Food and Drug Administration for the treatment of irritable bowel syndrome with constipation (IBS-C) as well as chro

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Primary care market will see major shifts by 2030 as payers, nontraditional providers gain ground

Fierce Healthcare

Two years ago, Bain and Company forecasted ma | Nontraditional providers will account for about one-third of the primary care market in 2030, according to Bain and Company. Payer-owned primary care, population-focused models and advanced primary care providers are all poised for growth.

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FDA signs off on Merus' first-in-class NRG1+ cancer drug Bizengri after brief delay

Fierce Pharma

Merus’ week keeps getting better. | The FDA had originally pushed its decision back by three months after a November manufacturing-related delay.

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Influenza Vaccine Least Effective for Children Facing Secondary Infection

Drug Topics

Researchers addressed vaccine effectiveness for individuals with direct household contacts that reported influenza.

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Combining Ruxolitinib and Supportive Anemia Care Enhances Myelofibrosis Treatment

Pharmacy Times

The data support the use of supportive anemia care agents in combination with ruxolitinib (Jakafi; Incyte Corp).

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STAT+: Wall Street wags say a bill to force insurers or PBMs to sell pharmacies has low odds

STAT

A proposed Senate bill that would prohibit companies that control health insurers or pharmacy benefit managers from owning pharmacies rattled investors on Wednesday, but some Wall Street analysts believe the legislation is unlikely to gain much traction, at least for now. The bipartisan bill , which would require divestiture within three years, is aimed at what the lawmakers call an “inherent conflict of interest” that has forced Americans to pay more for medicines and hastened the

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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