Hospital Pharmacy Europe

OCTOBER 25, 2024

A study has identified subtle changes in how immune cells respond to different severe febrile illnesses in children, which could lead to improved treatments. As clinicians, we may often see a child in the hospital or clinic with a fever and no other real defining symptoms, making an accurate diagnosis and targeted treatment difficult.’

Immunization 52

Immunization Hospitals Communication 52

STAT

MAY 15, 2024

Immune cells have to be removed from a patient, shipped to specialty sites, where they’re engineered with cancer-killing abilities, and then returned to the hospital for infusion back into patients. CAR-Ts have proven to be potent treatments for certain cancers, but they are complicated medicines to make.

Hospitals 117

Hospitals Immunization 117

European Pharmaceutical Review

FEBRUARY 24, 2023

University Hospital Erlangen in Germany is the first in the world to use chimeric antigen receptor (CAR) T-cells to successfully treat a patient suffering from a severe case of muscle inflammation (myositis). The researchers modified the patients’ own immune cells.

Immunization 128

Immunization Hospitals 128

STAT

MAY 10, 2023

Brigham and Women’s Hospital will launch a new institute focused on immunology and inflammation, thanks to a $100 million gift, the largest in the hospital’s history. The institute will also investigate the aging of the immune system and immune dysfunction in cancer.

Immunization 98

Immunization Hospitals 98

The Checkup by Singlecare

NOVEMBER 26, 2024

A 2022 study found that both B12 and B5 had protective effects against COVID infection, while a 2020 study found that vitamin B12 (when combined with vitamin D and magnesium) improved outcomes for elderly patients hospitalized with COVID-19. Vitamin C: Vitamin C is well known for its positive effects on the immune system.

Immunization 94

Immunization Hospitals FDA 94

Pharma Times

MAY 30, 2024

Affecting the immune system, various forms of SCID are estimated to affect one in 75,000 to 100,000 newborns

Immunization 56

Immunization Hospitals 56

STAT

JANUARY 5, 2023

million to BioVersys, which is developing an antibiotic to combat a type of bacteria that affects people with compromised immune systems and is increasingly responsible for infections in hospitalized patients. In its latest move, the fund is providing $7.5

Hospitals 104

Hospitals Immunization 104

Hospital Pharmacy Europe

AUGUST 22, 2023

An anti-IL17 peptide sequence has demonstrated high clinical efficacy in models of immune-mediated inflammatory conditions, warranting further clinical evaluation. In addition, when compared with secukinumab, the current gold-standard biologic, the anti-IL17 peptide gave rise to less off-target immune-related effects.

Immunization 52

Immunization Hospitals 52

STAT

AUGUST 3, 2023

A panel of advisers to the Centers for Disease Control and Prevention unanimously voted Thursday to recommend wide use among infants and some high-risk children of an antibody designed to protect against RSV , the country’s leading cause of infant hospitalization. Read the rest…

Immunization 98

Immunization Hospitals 98

Pharmacy Times

MAY 3, 2024

The results reinforce other real-world evidence from several broad infant immunization programs in the US, Spain, and France.

Hospitals 65

Hospitals Immunization 65

The Checkup by Singlecare

DECEMBER 16, 2024

And, be sure to stick with whole oranges instead of processed options like orange juice or dried fruit, says Raj Dasgupta , MD, an internist and program director at Huntington Health Hospital in California. Thats because they contain fiber, essential nutrients, and no added sugars, so theyre less likely to cause a blood sugar spike.

Immunization 98

Immunization Hospitals 98

Pharmacy Is Right For Me

AUGUST 26, 2024

You may think of a clinical pharmacist working in a community pharmacy or a hospital pharmacist working in an in-patient unit. Pharmacogenomic researchers discovered a genetic variant in the immune system that causes this life-threatening allergic reaction to Abacavir. What is your first thought when you think of a career in pharmacy?

Community Pharmacies 279

Community Pharmacies Immunization Hospitals 279

STAT

JANUARY 3, 2023

More specifically, 70 of the 93 top-selling drugs covered by the Medicare Part B program – which are typically pricier medicines that are administered by physicians or in hospitals – between 2018 and 2020 would have been subject to inflationary rebates each year, according to the analysis published in JAMA.

Immunization 98

Immunization Hospitals 98

Hospital Pharmacy Europe

APRIL 7, 2025

4 When conjugated to peptides or small molecules that specifically bind to receptors on tumour cells, such as somatostatin receptors or prostate-specific membrane antigens, beta radiation promotes the apoptosis of tumour cells, leading to the release of tumour antigens and the induction of a tumour-specific systemic immune response.

Immunization 52

Immunization Hospitals Compounding Labelling 52

pharmaphorum

JANUARY 26, 2021

Novartis has said that its investment in digital technology has helped it to ride out the worst of the pandemic, although sales of some of its newly-launched products have been affected by a fall in prescriptions and hospital visits. billion and profits growing 2% to just over $3 billion.

Hospitals 111

Hospitals Immunization 111

pharmaphorum

SEPTEMBER 11, 2022

With the results in hand, the developers of the therapy – from the Netherlands Cancer Institute and Norway’s National Center for Cancer Immune Therapy – say they now intend to file for regulatory approvals in Europe before the end of the year, without a commercial partner “to try to ensure that it remains affordable.”

Immunization 105

Immunization Chemotherapy Hospitals 105

The Checkup by Singlecare

DECEMBER 13, 2023

While there’s no sore throat “diet” per se, eating to support your immunity is essential—before, during, and after an illness. A well-balanced diet rich in fruits and vegetables helps keep your immune system strong, which can help prevent you from catching a cold or flu. What food is good for a sore throat?

Immunization 128

Immunization Hospitals 128

pharmaphorum

OCTOBER 14, 2020

The latest case was recorded in the Lancet Infectious Diseases journal and involved a 25 year-old man with no known immune disorders or underlying conditions. Although the authors said further research was needed, they said the findings suggested previous exposure may not confer immunity and that people should comply with control measures.

Immunization 98

Immunization Hospitals 98

European Pharmaceutical Review

JANUARY 4, 2024

Immunotherapy drugs like teclistamab can result in potentially fatal side effects, including CRS and immune cell-associated neurotoxicity syndrome (ICANS). An overactive immune response [is] the hallmark of CRS,” Landgren added. The drug tocilizumab for example, has been used historically to treat CRS from immunotherapies.

Immunization 97

Immunization Hospitals FDA 97

European Pharmaceutical Review

JULY 13, 2023

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

Immunization 98

Immunization Hospitals FDA 98

Hospital Pharmacy Europe

JULY 18, 2023

The primary outcome of interest was a physician-verified positive immune-mediated oral penicillin challenge within one hour after the intervention. In the five days following the oral penicillin challenge, a total of nine immune-mediated adverse events were recorded in the intervention group and 10 in the control group.

Immunization 98

Immunization Labelling Hospitals 98

Pharma Times

JANUARY 5, 2024

Vd1-gd T cells were effective in predicting positive responses to ICI therapy

Immunization 59

Immunization Hospitals 59

pharmaphorum

SEPTEMBER 16, 2020

RECOVERY (Randomised Evaluation of COVid-19 thERapY) trial is being conducted in NHS hospitals and has already demonstrated the benefits of dexamethasone as a treatment for COVID-19, showing the cheap steroid cut recovery times and reduced mortality.

Hospitals 98

Hospitals Labelling Immunization 98

Board Vitals - Pharmacist

JANUARY 11, 2024

Here are some of their stories: Forty-eight years ago, in 1976, a pediatric patient was admitted to Hammersmith Hospital, London. Luckily, an on-duty hospital nurse had read bestselling mystery writer Agatha Christie’s 1961 novel, “The Pale Horse.” Oh, and you want a nice cold Coca Cola with your medical history here?

Retail Drug Stores 98

Retail Drug Stores Hospitals Insurance Patient Care 98

European Pharmaceutical Review

FEBRUARY 1, 2024

Positive results from the first global study for chimeric antigen receptor (CAR)-antologous T cell (BCMA CAR T) injection (Equecabtagene Autoleucel) in immune-mediated necrotising myopathy (IMNM), suggest that the cell therapy could provide a new therapeutic option for antibody-mediated autoimmune disorders.

Immunization 98

Immunization Hospitals 98

European Pharmaceutical Review

FEBRUARY 1, 2024

Epcoritamab is designed to simultaneously attach to two different cells, one immune T cell and one cancerous lymphoma cell, bringing them together. In this way, the immune T cell is activated to eliminate the cancerous lymphoma cell, based on a EBioMedicine paper published in 2020.

Immunization 98

Immunization Hospitals 98

pharmaphorum

SEPTEMBER 12, 2022

Reddy says one of LabCorp’s groundbreaking tests, OmniSeq INSIGHT, is an “all-in-one test that includes comprehensive genomics and immune profiling from a single tissue sample to identify all FDA-approved therapeutics, confirm immunotherapy eligibility for a patient, and identify appropriate nearby clinical trials.”.

Immunization 105

Immunization Hospitals FDA Patient Care 105

The Checkup by Singlecare

SEPTEMBER 22, 2023

But young children, older adults, and individuals with weakened immune systems are at high risk of severe, potentially life-threatening RSV illness. Infants have a high risk because their airways may be small enough to close up when inflamed and their immune systems aren’t yet fully developed. Is there a vaccine for RSV?

Vaccines 105

Vaccines Immunization Insurance FDA 105

European Pharmaceutical Review

MARCH 17, 2023

In a first-of-its-kind commercial agreement, Great Ormond Street Hospital NHS Foundation Trust (GOSH) will work with Leucid Bio to manufacture LEU011, a lateral Chimeric Antigen Receptor (CAR) targeting NKG2D ligands. The CAR T therapy will be used in clinical studies for solid tumours and haematological malignancies.

Immunization 115

Immunization Hospitals 115

pharmaphorum

AUGUST 31, 2022

In May, a Phase 2 study started, comparing Kaiku’s electronic patient-reported outcome (ePRO) approach to evaluating immune-related adverse events to the standard model of care in cancer patients treated with checkpoint inhibitor drugs, with results due towards the end of 2023 or in early 2024.

Chemotherapy 116

Chemotherapy Immunization Hospitals 116

Pharmacy Is Right For Me

FEBRUARY 1, 2024

During one such episode, Jorie was rushed to the hospital where she remained for over 10 days due to complications. Initial Hesitations By age 16, Jorie had earned her technician license and actively volunteered at a hospital pharmacy, solidifying her commitment to the pharmacy profession.

Community Pharmacies 130

Community Pharmacies Hospitals Patient Care Immunization 130

pharmaphorum

JANUARY 26, 2023

More specifically, CAR-T cell therapy engineers a patient’s own immune cells (T-cells) to detect, target, and destroy cancer cells. CAR-T cell therapy is an individualised treatment for patients, currently licensed for people living with some types of blood cancer. Since then, over 500 patients in England have received axi-cel.

Chemotherapy 96

Chemotherapy Immunization Hospitals 96

Hospital Pharmacy Europe

APRIL 19, 2023

Endocan (EC) is a circulating proteoglycan, that has involvement in immunity, inflammation, and endothelial function. BMC Gastroenterol 2023 The post Endocan a promising biomarker for assessing disease extent in ulcerative colitis appeared first on Hospital Pharmacy Europe.

Immunization 97

Immunization Hospitals 97

Hospital Pharmacy Europe

JULY 31, 2023

Redefining disease management for gMG Dr John Brandsema, from the Children’s Hospital of Philadelphia and the primary investigator in the study, said: ‘This approval represents a significant advance in care for paediatric patients with refractory gMG, who previously had no targeted treatment options to help manage their condition.

Hospitals 97

Hospitals Communication Immunization 97

pharmaphorum

SEPTEMBER 15, 2020

The antibody – called lenzilumab – targets colony stimulating factor 2 (CSF2) and granulocyte-macrophage colony stimulating factor (GM-CSF), two cytokines that are linked to the runaway immune response that can result in serious lung damage in COVID-19.

Mayo Clinic 97

Mayo Clinic Immunization Hospitals 97

Hospital Pharmacy Europe

FEBRUARY 23, 2023

The complement system is a component of the immune system that is central to the detection and destruction of invading pathogens and consists of three pathways. The post FDA approves Syfovre for geographic atrophy in advanced age-related macular degeneration appeared first on Hospital Pharmacy Europe.

FDA 98

FDA Immunization Hospitals 98

ISPE

OCTOBER 10, 2022

The process of creating a TIL therapy starts in the hospital operating room, where a surgical oncologist removes tumor specimens from the patient. The final product is frozen and shipped back to the hospital.

Hospitals 98

Hospitals Immunization 98