Pharmacy Times

OCTOBER 3, 2024

By utilizing a lower dose, patients can avoid potential adverse events and high financial burden.

Immunization 96

Immunization 96

Pharmacy Times

SEPTEMBER 12, 2024

Programs can take several forms, including on-site clinics, voucher programs, and in-store events

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Immunization Vaccines 56

pharmaphorum

NOVEMBER 1, 2024

The 8th Antigen-Specific Immune Tolerance Drug Development Summit is an event organised by Hanson Wade. Discover the latest developments and networking opportunities at this leading industry conference.

Immunization 52

Immunization 52

pharmaphorum

MARCH 12, 2021

Several cases of immune thrombocytopenia – a disorder characterised by low levels of blood platelets that can lead to bruising and bleeding – were reported in the European Medicines Agency’s safety surveillance database.

Vaccines 145

Vaccines Labelling Immunization 145

STAT

OCTOBER 14, 2024

Jasper Therapeutics, a biotech looking to make stem cell transplants less taxing and to treat immune-mediated diseases, reported on Monday that its experimental drug helped patients with a chronic skin condition in an initial and closely watched clinical trial. Among patients given a 120-mg dose, 10 of 12 had a complete response to treatment.

Immunization 111

Immunization 111

pharmaphorum

SEPTEMBER 1, 2020

Sanofi has drawn another blank in its attempt to repurpose its IL-6 drug Kevzara to tackle the extreme immune reaction seen in serious cases of COVID-19. In severe cases of COVID-19, patients suffer a “cytokine storm” where the immune system becomes overstimulated and attacks the body.

Immunization 111

Immunization Hospitals 111

pharmaphorum

JULY 6, 2021

While these types of tests are important, they don’t tell the whole story, as they can’t provide information on whether an individual has built an immune response to COVID-19, either through vaccination or through a previous infection. This is where antibody tests come in. ” . . The Importance of Antibody Certificates.

Immunization 111

Immunization Vaccines 111

Hospital Pharmacy Europe

JULY 6, 2023

With Hospital Pharmacy Europe ’s inaugural Clinical Excellence in Respiratory Care event in conjunction with Hospital Healthcare Europe fast approaching, there are just a few days left to register. The post Time running out to register for MDT respiratory event appeared first on Hospital Pharmacy Europe.

Hospitals 52

Hospitals Patient Care Immunization 52

Hospital Pharmacy Europe

AUGUST 15, 2023

A perioperative approach that includes both neoadjuvant and adjuvant immune checkpoint inhibition with pembrolizumab significantly improves disease outcomes for patients with early-stage non-small-cell lung cancer (NSCLC), according to the findings of a trial by an international research group.

Chemotherapy 96

Chemotherapy Immunization Hospitals 96

European Pharmaceutical Review

DECEMBER 14, 2022

Personalised cancer vaccines are designed to prime the immune system so a patient can generate a tailored anti-tumour response specific to their tumour mutation signature. mRNA-4157/V940 stimulates an immune response by generating specific T cell responses based on the unique mutational signature of a patient’s tumour.

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Vaccines Immunization 116

pharmaphorum

JANUARY 15, 2021

Latest data give hope that the vaccine could be added to the campaign after phase 1/2a data showed that the shot provided an immune response that lasted for at least 71 days, the duration of time measured in the study involving patients aged 18-55 years. J&J expects to file with the FDA first, followed by other regulators.

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Vaccines Immunization FDA 119

STAT

DECEMBER 12, 2023

Researchers also found that while adding Darzalex increased the rate of certain side effects, such as diarrhea and low immune cell counts, these adverse events were manageable and didn’t lead to more participants leaving the study. Continue to STAT+ to read the full story…

Immunization 107

Immunization 107

European Pharmaceutical Review

DECEMBER 15, 2023

Adverse events observed with mRNA-4157 in KEYNOTE-942 remain consistent with those previously reported. The most common adverse events were fatigue, injection site pain and chills. Keytruda is an immunotherapy that works by increasing the ability of the body’s immune system to help detect and fight tumour cells.

Vaccines 115

Vaccines Research Laboratories Immunization 115

pharmaphorum

SEPTEMBER 30, 2020

As expected, patients in the study formed two populations: those who had already mounted an immune response and those whose immune response was not yet adequate. Serious adverse events occurred in 2 placebo patients, 1 low dose patient and no high dose patients. There were no deaths in the trial.

Immunization 135

Immunization 135

European Pharmaceutical Review

SEPTEMBER 4, 2023

Included in Issue 4 of European Pharmaceutical Review : FOREWORD Dissolution testing – a dual role David Elder, David P Elder Consultancy REGULATORY INSIGHT EU packaging reform: a prescription for change?

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Packaging Vaccines Immunization 97

Pharmacy Times

NOVEMBER 29, 2022

Treatment with immune checkpoint inhibitors have the potential for immune-related adverse events, such as psoriasis.

Immunization 65

Immunization 65

pharmaphorum

AUGUST 27, 2020

Moderna has said that its coronavirus vaccine stimulated an immune response in older people in phase 1 trials, suggesting that the jab is effective in the age groups most susceptible to COVID-19. There were also no serious adverse events reported. The company’s shares rose about 6% on the news.

Vaccines 111

Vaccines Immunization 111

European Pharmaceutical Review

MARCH 26, 2024

Moderna’s next-generation COVID-19 vaccine mRNA-1283 demonstrated a higher immune response against SARS-CoV-2, interim results from the company’s Phase III trial show. These findings were based on data comparing the treatment to mRNA-1273.222 (Spikevax ® ), Moderna’s licensed vaccine for the condition.

Vaccines 110

Vaccines Immunization 110

Fierce Pharma

JUNE 29, 2023

By 2030, Sanofi figures its immunizations could generate more than €10 billion in annual sales, the company said during a vaccines R&D event Thursday. While Dupixent often steals the show, Sanofi isn’t sleeping on its vaccine franchise. |

Vaccines 77

Vaccines Immunization 77

European Pharmaceutical Review

AUGUST 2, 2023

This is an additional ingredient designed to trigger a stronger immune response. The vaccine demonstrated a strong immune response in the trial. In a clinical trial, this vaccine was shown to faciliate a strong immune response against the Omicron BA.1 1 variant, in addition to the original 2020 strain.

Vaccines 98

Vaccines Immunization 98

Pharma Times

APRIL 20, 2023

IMM-1-104 found to be well tolerated with no dose limiting toxicities or serious adverse events

Immunization 48

Immunization 48

Pharmacy Times

DECEMBER 9, 2024

Panelists discuss how bispecific antibody therapies in relapsed/refractory multiple myeloma commonly present with cytokine release syndrome (CRS), immune effector cellassociated neurotoxicity syndrome (ICANS), and increased infection risks, while talquetamab specifically exhibits distinctive adverse events including nail changes, skin reactions, and (..)

Immunization 65

Immunization 65

Pharmacy Times

DECEMBER 6, 2022

Biomarker testing and management of immune-related adverse events are key roles for pharmacists.

Immunization 65

Immunization 65

Pharmaceutical Technology

MARCH 31, 2023

Moreover, these events also have ramifications for planned clinical trials. Eligibility for the UK’s National Health Services (NHS) booster programmes in England is restricted to those ages 75 years and above or individuals with weakened immune systems. The NHS will be using Covid-19 vaccines manufactured by Pfizer, Moderna and Sanofi.

Vaccines 110

Vaccines Immunization 110

European Pharmaceutical Review

NOVEMBER 24, 2022

Immune-mediated adverse reactions (ARs) occurred in 21 percent of patients treated with Libtayo ® and led to permanent discontinuation in 4.6 The most common immune-mediated ARs were hypothyroidism (6.8 percent), hyperthyroidism (3 percent), immune-mediated pneumonitis (2.6 percent), immune-mediated hepatitis (2.4

Chemotherapy 98

Chemotherapy Immunization Adverse Reactions Hospitals 98

pharmaphorum

FEBRUARY 10, 2021

Given the large unmet clinical need in this oncology indication and aligned with recent clinical trial progress, the Triple Negative Breast Cancer (TNBC) Drug Development Digital Summi t has been created to provide insight into industry- and academic-led clinical programs developing immune checkpoint, DDR inhibitor, ADC and other novel agents.

Immunization 133

Immunization Vaccines 133

PharmaShots

APRIL 5, 2023

Shots: The P-IIb dose-finding study evaluates vidofludimus calcium vs PBO in patients at 78 study sites in the US and EU The 50wk. maintenance phase results showed a dose-linear increase in clinical remission, 10 & 30mg, qd of vidofludimus calcium showed clinical remission rate (42.3% & 61.5%

Immunization 40

Immunization 40

Pharmaceutical Technology

NOVEMBER 14, 2022

In lupus, the body’s immune system starts to attack its own cells. Saphnelo is also being studied in a Phase III trial in lupus nephritis, where a person’s immune system targets the kidneys, eventually leading to kidney failure. As per AstraZeneca's recent Q3 earnings, Saphnelo has yielded $69 million to date this year.

Immunization 144

Immunization FDA 144

pharmaphorum

JANUARY 10, 2023

Other IgG proteases are being developed to tackle the issue of pre-existing immunity against AAV, but according to Selecta chief executive Carsten Brun these tend to be derived from common human pathogens – which means they themselves can be the target of existing antibodies. .”

Immunization 119

Immunization FDA 119

pharmaphorum

FEBRUARY 3, 2021

The emergence of novel base editing technologies that do not generate double-strand breaks (DSBs) offer a promising and safer alternative to fine-tune the next generation of immune cell therapies, especially as our need to perform complex multi-gene alterations increases. Another area for potential improvement is the source of immune cells.

Immunization 98

Immunization Vaccines 98

Hospital Pharmacy Europe

JULY 18, 2023

The primary outcome of interest was a physician-verified positive immune-mediated oral penicillin challenge within one hour after the intervention. In the five days following the oral penicillin challenge, a total of nine immune-mediated adverse events were recorded in the intervention group and 10 in the control group.

Immunization 98

Immunization Labelling Hospitals 98

Digital Pharmacist

JANUARY 16, 2023

From cancer prevention to diabetes awareness, these events help bring communities together. World Immunization Week: April 24-30. National Immunization Awareness Month. Also, don’t forget to promote these awareness events on your website and at your pharmacy. National Cancer Prevention Month. National Kidney Month.

Immunization 98

Immunization Vaccines Communication Hospitals 98

European Pharmaceutical Review

JUNE 27, 2023

Participants with greater than 90 days of follow-up had elimination of severe hypoglycaemic events in the evaluation period. It is delivered by an infusion into the hepatic portal vein and requires chronic immunosuppressive therapy to protect the islet cells from immune rejection. This eliminates the need for immunosuppression.

Immunization 98

Immunization 98

European Pharmaceutical Review

SEPTEMBER 13, 2022

The current standard of care for patients with recurrent, unresectable or metastatic disease is immune checkpoint inhibitor monotherapy targeting anti-programmed death receptor 1 (anti-PD-1) and programmed death ligand 1 (PD-L1), but only about half of patients respond to this therapy.

Immunization 96

Immunization 96

pharmaphorum

MARCH 31, 2021

The decision to restrict use of the shot in under-60s comes from Germany’s independent vaccine committee known as STIKO made the decision based on available data about the blood clotting events. All but two of the 31 cases involved women aged 20 to 63 while two men affected were 36 and 57 years old, the institute said.

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Vaccines Immunization 116

The Checkup by Singlecare

JUNE 7, 2024

This rash-causing virus is certainly prevalent, but it’s also avoidable thanks to immunizations like Shingrix. Shingrix contains dead pieces of this virus, called antigens, and adjuvant proteins, which allow the immune system to bolster its defenses against it. “By For most people, yes. a pharmacist, speaker, and medical writer.

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Immunization Vaccines Dosage FDA 96

European Pharmaceutical Review

JULY 13, 2023

The field of immunotherapy is constantly evolving with the ultimate goal to develop new treatments that help the body’s immune system fight cancer. Immune cells, such as T cells and natural killer (NK) cells, have the inherent ability to combat diseases, including cancer, but are often inhibited by the body’s own suppressive mechanisms.

Immunization 98

Immunization Hospitals FDA 98