Sat.Jul 03, 2021 - Fri.Jul 09, 2021

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Moderna plans triple vaccine targeting flu, COVID and RSV

pharmaphorum

Buoyed by the success of its COVID-19 vaccine, Moderna has started a phase 1/2 trials of its mRNA-based shot for seasonal influenza, targeting four different flu strains. . The first patents have now been enrolled into the study of the shot – codenamed mRNA-1010 – which is designed to generate antibodies against influenza A H1N1, H3N2 and influenza B Yamagata and Victoria – all of which are recommended by the World Health Organization (WHO).

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Medicenna takes on deadly brain cancer in clinical trial

Outsourcing Pharma

The immunotherapy firm is conducting a Phase III trial centered on an innovative approach to treating recurrent glioblastoma, an aggressive brain cancer.

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Oxford researchers launch HIV vaccine trial

Pharma Times

Vaccine will be evaluated in 13 HIV-negative adults aged 18-65 years old

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Collaboration & Agility – Core Themes & Lessons from Reuters Pharma USA 2021

Pharma Marketing Network

At this year’s Pharma USA conference, C ollaboration was the theme of the opening keynote session and a common thread woven throughout the event as industry leaders gathered to discuss how to move “Beyond Normal” to shape the future of health. In her opening statement, Izzy Gladstone, Reuters’ Head of Marketing, Pharma & Healthcare, challenged attendees to not return to our old ways of working.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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UK biotech ‘booming’ as sector rakes in £1.6bn in Q2 financing

pharmaphorum

The UK’s biotechnology sector is going through a purple patch, attracting almost £1.6 billion ($2.2 billion) in financing in the three months to end-May – which is a record for the industry. The new figures – from the BioIndustry Association and Clarivate – were dominated by more than £1 billion in venture capital funding for UK biotech and life sciences companies, headlined by DNA sequencing company Oxford Nanopore’s £195 million raise in May that was just shy of the £205 million re

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Rare disease specialists talk resources, research and hope

Outsourcing Pharma

During the Rare/Orphan Diseases, Special Patient Population webinar, a group of industry experts discussed challenges and opportunities faced in the field.

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Questions You Need to Ask Your Pharmacist

Lifewell Rx Pharmacy

Pharmacists from your community pharmacy in Kentucky are the most approachable healthcare professionals you can talk to. As medication experts you can trust, they can answer your questions regarding your care plan, medications, and disease management. This may include explaining how to take your medication or providing more information about a disease to enhance your health.

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Imugene HER2 vaccine hits target in stomach cancer trial

pharmaphorum

A peptide vaccine developed by Australia’s Imugene has reduced tumour size in around half of patients with HER2-positive gastric or gastroesophageal junction (GEJ) cancer in a phase 2 trial. The interim readout from the 39-patient HERIZON trial found 50% of patients treated with the HER-Vaxx (IMU-131) vaccine on top of chemotherapy achieved a partial response or better, compared to 29% of patients given only chemo.

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Pharma SAAS solutions must balance safety, efficiency: IQVIA

Outsourcing Pharma

A leader from IQVIA suggests what to look for when seeking ways to automate drug safety processes, while maintaining security and customer satisfaction.

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Kuano raises £1m to further develop AI drug discovery platform

Pharma Times

Company is aiming to transform the discovery of therapeutics focused on enzyme inhibition

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Is There a Link Between Low Testosterone and Depression?

Pharma Mirror

Testosterone is an essential hormone and steroid that affects many physiological functions. It is naturally more prevalent as an androgynous hormone in men, and it is therefore much more essential for them to have adequate amounts of it. However, with age, levels of this primary hormone can take a dive, usually for the worse. Symptoms of low testosterone may include weight gain, anxiety, low energy levels, low libido, insomnia, loss of concentration, and low mood.

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COVID-19 neutralising antibody tests – an integrated approach

pharmaphorum

Nina Garrett, R&D director at Abingdon Health discusses the key role antibody testing is playing in the pandemic and how an integrated approach with vaccines could help normal life resume. Millions of tests for COVID-19 are taken worldwide every day, as they become an increasingly important tool for our return to normality. Testing programmes have been rolled out by governments globally with the important purpose of tracking the spread of the SARS-CoV-2 virus and letting individuals know whe

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Duke University, HumanFirst partner to assess digital clinical measuring tools

Outsourcing Pharma

The two entities will work together to evaluate digital sensors and other tools used in clinical research, checking the items for accuracy and equity.

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AZ, Amgen’s asthma med tezepelumab gains FDA priority review

Pharma Times

Priority review comes following positive results from the Phase III NAVIGATOR trial

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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SHSMD Connections 2021 | September 19-21 In Person | October 20-21 Virtual

Pharma Marketing Network

Join the Society for Health Care Strategy and Market Development (SHSMD) at their annual conference, SHSMD Connections 2021 this autumn. This annual conference is beneficial for health care strategists at any stage in their career that want to connect and learn from other industry professionals. Participants come from across the nation and possess a wide range of expertise about various facets of the health care strategy sector.

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NICE rejects Orchard’s gene therapy for rare childhood disease MLD

pharmaphorum

Orchard Therapeutics’ gene therapy for rare childhood disease metachromatic leukodystrophy (MLD) Libmeldy has been rejected for NHS use by NICE in draft guidance. The agency said that while there was evidence of a short-term benefit with Libmeldy (atidarsagene autotemcel or OTL-200 ), assumptions about its long-term effects are uncertain, making it unclear whether it will offer value for money to the NHS.

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CRO Parexel to be acquired by Goldman Sachs in $8.5b deal

Outsourcing Pharma

The global contract research organization has announced it will be purchased by Goldman Sachs Asset Management and EQT Private Equity.

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Merck partners with Innervia on bioelectronic therapy development

Pharma Times

Collaboration will focus on the development of smart neurostimulators for the treatment of severe chronic diseases

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Dextromethorphan Clinical Pearls

Med Ed 101

In this article, we’d like to share some of the most common dextromethorphan clinical pearls that you should be aware of. Dextromethorphan (DXM) is an over-the-counter medication often found in many of the Robitussin products, among others. It is approved to treat cough in adults and children 12 and older. Relief starts 15-30 minutes after […].

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GSK cancer head Hoos exits, takes top role at biotech Scorpion

pharmaphorum

GlaxoSmithKline’s head of oncology Axel Hoos has resigned from the company, and will take up a new role as chief executive of US biotech Scorpion Therapeutics. . Hoos is leaving GSK after nine years, a period that saw a complete revamp of the unit including the wholesale divestment of cancer drugs to Novartis in a $16 billion deal announced in 2014 – which completed as he took over the division.

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People on the Move: July 2021

Outsourcing Pharma

This monthâs news on hires, promotions, acquisitions, and expansions includes items about Javara, Elligo, Lonza, Yourway, Medable, and other notable firms.

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Valneva’s chikungunya virus vaccine granted breakthrough designation

Pharma Times

Currently, no preventative vaccines or effective treatments are available for the chikungunya virus

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Healthcare Businesswomen’s Association Announces Appointment of New CEO

Pharma Marketing Network

FAIRFIELD, NJ, 30 June, 2021- The Healthcare Businesswomen’s Association Board of Directors announces the appointment of Susan O’Connor as Chief Executive Officer of the global not-for-profit association, ushering in a new chapter in its mission of advancing women in healthcare. Ms. O’Connor will succeed current President and CEO Laurie Cooke, who will step down for a well-earned retirement after leading the organization since 2006.

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Israel says Pfizer jab less effective against COVID-19 delta

pharmaphorum

The Israeli Ministry of Health has reported data suggesting that the efficacy of the Pfizer/BioNTech COVID-19 vaccine has become less effective at preventing the spread of the coronavirus after the emergence of the delta variant. The vaccine still seems to be able to prevent hospitalisation and severe cases of COVID-19, but its efficacy in preventing symptomatic infections seems to have fallen from a high of 94% at the start of the rollout to 64% now, which it attributes to the emergence of the

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BMS, GRYT Health collaborate on patient advocacy platform

Outsourcing Pharma

The two organizations have joined to create the Advocacy Exchange, a virtual platform designed to bring together patients, advocates and industry leader.

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Study finds lower COVID-19 infection prevalence in fully vaccinated people

Pharma Times

COVID-19 infection rates were three times lower in fully vaccinated people compared to unvaccinated people

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Novartis tries to rescue stalled inclisiran filing with FDA

pharmaphorum

Novartis has tried to get its marketing application for high cholesterol therapy inclisiran in the US back on track, after the FDA rejected it last year, by changing the factory that makes the drug. The US regulator issued Novartis with a complete response letter (CRL) for inclisiran in December, citing “unresolved facility inspection-related conditions” at a third-party manufacturing site run by Corden Pharma near Milan, Italy.

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Herd immunity is nice – but what about me?

pharmaphorum

Shahrokh Shabahang discusses why we need a personalised approach to COVID-19 immunity testing. To-date, the battle against COVID-19 has been waged largely in the field of public health, using a series of binary, black-and-white thresholds to measure progress. The number of positive cases per 100,000 people, yes/no results on PCR tests, absence or presence of antibodies – these have set the benchmarks used to determine when we can open our schools and restaurants, remove our masks and resume some

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Eyeing delta surge, Pfizer will file COVID-19 booster next month

pharmaphorum

With the COVID-19 delta variant has become the dominant strain circulating in the US, Pfizer and BioNTech have said they will ask the FDA and other regulators to approve a third dose of their Comirnaty vaccine to guard against a winter surge in cases. . The two companies have revealed data from an ongoing trial of the booster Comirnaty (BNT162b2) jab, saying that a dose given six months after the second dose stimulates a strong antibody response against both the original wild type and the worris

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FDA rejects Provention’s type 1 diabetes drug teplizumab

pharmaphorum

The FDA indicated something was not well with Provention Bio’s filing for type 1 diabetes therapy teplizumab in April when it delayed its review. Now, the agency has rejected the application entirely, sending the company’s shares into a steep slide. The complete response letter (CRL) for teplizumab as a treatment to delay clinical type 1 diabetes in at-risk individuals reiterates the FDA’s concerns around the pharmacokinetics (PK) data for the antibody.

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Another hurdle down as EU clears AstraZeneca’s Alexion takeover

pharmaphorum

The European Commission has given competition clearance to the $39 billion acquisition of Alexion by AstraZeneca, leaving the UK as the last remaining obstacle to getting the deal across the line. The EU approval comes after the merger has already been okayed by the US, Japan and a number of other countries around the world, and AZ says it is now hoping to completing the transaction by the end of this quarter.

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Performance.io appoints Jason Brown as global chief commercial officer

pharmaphorum

UK-based online marketing agency Performance.io (PIO) has appointed Jason Brown as it’s global chief commercial officer. Brown has held several senior leadership positions at pharma companies including Sanofi and Novartis, before joining sales force benchmarking organisation, STEM where he was promoted to President of EU5 and global COO. His most recent role was as chief commercial officer at Pharmaspectra, where he was responsible for the company’s international growth.

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How digital pathways are changing healthcare

pharmaphorum

As demonstrated throughout COVID, digital health is no longer experimental. Digital technologies are proving their value by allowing for better care, improved adherence and a more connected ecosystem between doctors, patients and pharma. Ampersand Health has been working in the space since 2015 and has seen it evolve from a niche approach with limited acceptance to widespread acceptance and deployment across disease areas in a matter of years.