Sat.Nov 28, 2020 - Fri.Dec 04, 2020

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iRhythm digital heart monitoring service backed by NICE

pharmaphorum

A heart monitor developed by iRhythm has become the first product to be endorsed by NICE in a pilot project covering digital health technologies. In new guidance, the health technology assessment (HTA) agency has recommended iRhythm’s Zio XT service for detecting abnormal heart rhythms – provided NHS organisations that deploy it collect evidence of its benefits.

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(BEST) over the counter ANTIBIOTIC cream

Druggist

In today’s post, I will review over the counter antibiotic creams in the UK. Some over the counter creams, gels and ointments available in the UK, have an ‘antibiotic’ properties however most of them are not genuinely classified as antibiotics, due to their limitations in terms of elimination of infections. The main focus of this post is to review use and the effectiveness of ‘antibiotic’ creams, supported any existing evidence.

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Trending Sources

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COVID-19 collaboration to study patient risk via blood

Outsourcing Pharma

Health tech specialists GoodCell are working with the New York Blood Center to identify COVID-19 patients with elevated risk of adverse clinical outcomes.

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Colchicine added to UK’s COVID-19 ‘RECOVERY’ trial

Pharma Times

Commonly used anti-inflammatory drug added to list of potential treatments

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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A history of Pfizer

pharmaphorum

Few companies embody the term ‘pharma giant’ as much as Pfizer. Here we take a look at the colourful history of one of the biggest drugmakers in the world. Pfizer was founded in 1849 by two recent German immigrants to the USA, Charles Pfizer and Charles Erhart. Both in their mid-twenties, the two men set up what was initially a fine chemicals business in a Brooklyn factory, using a loan from Pfizer’s father as capital.

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What Can Supplements Really Do For Health and Beauty?

Pharma Mirror

Taking a health supplement can positively impact your health and beauty if you choose the right one for your needs. According to Mayo Clinic, the benefits of supplements specifically apply to pregnant people (subject to doctor’s recommendation), over the age of 50, who have food allergies or digestive conditions or miss large food groups in their diet.

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UK approves Pfizer/BioNTech’s COVID-19 vaccine

Pharma Times

First doses for emergency use will be delivered 'immediately'

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Pfizer cut vaccine production targets because of raw material shortage – reports

pharmaphorum

Pfizer slashed its production targets for its COVID-19 vaccine because of a lack of raw materials for its supply chain, according to press reports. The big pharma has said in recent weeks that it expects to produce 50 million doses of the vaccine it developed with the German BioNTech, down from an earlier target of 100 million doses. That’s enough to inoculate 25 million people as the dosing schedule involves two shots three weeks apart.

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The Keto Diet: A Beginner’s Guide on Making the Switch to Keto

Pharma Mirror

The keto diet, also known as a ketogenic diet, is a type of food-based lifestyle that many people adopt. Essential, it lets you eat foods that are very high in fat and low in carbohydrates. The keto diet lowers insulin levels and increases your body’s ability to burn fat. This diet type is very alluring as it keeps you healthy and feeling full, unlike other diets.

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Dive into the digital evolution of clinical trials

Outsourcing Pharma

Taking place December 9, the Digital Advances in Clinical Trials webinar covers notable advances in clinical trial technology, and the future of the field.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Fermented Sauerkraut the Frugal Way to Feed Your Gut!

That Frugal Pharmacist

By Popular Demand: My Step By Step Guide and Homemade Fermented Sauerkraut Recipe! If you’re looking to begin making fermented foods, sauerkraut is a cheap and easy option to try. Read below and see how easy it is to make homemade sauerkraut. What, not a money thing?! There’s more to my life than finance! And … Fermented Sauerkraut the Frugal Way to Feed Your Gut!

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Healthware Group buys Finnish digital agency Make Helsinki

pharmaphorum

Healthcare agency, consultancy and digital health group Healthware Group has acquired Finland-based digital service development and creative agency Make Helsinki. The acquisition builds on prior collaborations between the two organisations, including in best-in-class full-service agency offerings, digital transformation, technology/enterprise solutions and corporate venturing.

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Vaccine nationalism, CDMO expansion, AMR and dual sourcing predicted in 2021

Pharma Mirror

The new report looks ahead to a post-pandemic 2021 with pharma manufacturing capacity and payment structures shifting as new sourcing strategies emerge Amsterdam: A new report from CPhI explores the potential implications in 2021 of impending vaccine approvals, a new administration in the White House and a return to dual supply chain strategies. The report – which summarises expert analysis into 12 key findings – foresees a particularly positive outlook for the pharma manufacturing supply chain

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Janssen partners with Koa Health on digital depression treatments

Outsourcing Pharma

The global pharma firm will work with the digital mental health solutions specialist on solutions for treatment-resistant depressive order patients.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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PureTech launches phase II ‘long COVID’ drug trial

Pharma Times

LYT-100 will be evaluated in patients with persistent symptoms caused by COVID-19

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Valneva accelerates Lyme disease vaccine R&D project with Pfizer

pharmaphorum

Valneva has said it plans to accelerate research into its Lyme disease vaccine candidate VLA15, bringing forward a trial including children into the first quarter of 2021. Subject to approval from regulators the vaccine specialist said it plans the trial known as VLA15-221 as a randomised, observer-blind phase 2 study including around 600 healthy people aged 5-65 years of age.

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Vectura signs agreement to support the development of VR588 to treat asthma

Pharma Mirror

Chippenham, UK: Vectura Group plc, an industry leading inhalation CDMO, today announces that it has signed a global out licence and development agreement with Kinaset Therapeutics Inc. for the development and commercialisation of VR588, a preclinical novel inhaled pan-JAK inhibitor for the prevention and treatment of severe asthma. Pan-JAK inhibitors have been developed and tested in clinical trials, approved and commercialised for many different indications but mainly for the treatment of chron

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Medable lands $91m to fuel decentralized trial tech

Outsourcing Pharma

The Series C funding will be used to help accelerate the research industryâs adoption of decentralized and digital clinical trial technology.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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COVID-19 could cause long-term lung damage, research finds

Pharma Times

Research conducted at Oxford University used new scanning method

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Healthcare that no longer leaves out the patient

pharmaphorum

For so long the US healthcare system was built around the provider, with appointments and services set by the provider (along with insurance reimbursement systems). This structure relies on in-person visits of patients to operate and become profitable. But when the industry suddenly shifted due to COVID-19, so too did the power dynamics of the patient-provider relationship.

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FIP publishes Position Statement on emerging technologies and pharmacy practice

Pharma Mirror

The Hague — The digital era is radically changing how technology is used, and new technologies are set to have major impacts on how people live and work. How pharmacists and pharmacy organisations can rise to the challenge of these technologies and embrace them is set out in a new Position Statement on emerging technologies and pharmacy practice released by the International Pharmaceutical Federation (FIP) today.

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Latest FDA COVID-19 news

Outsourcing Pharma

As the pandemic continues to impact the globe, the agency has kept busy issuing EUAs for potential treatments, and cited sellers of unapproved treatments.

FDA 52
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Bayer inks deal with Blackford Analysis to develop radiology AI platform

Pharma Times

Agreement will aim to develop a platform to support radiologists' decision-making

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‘Knowledge is power’ for rare diseases and NAbs

pharmaphorum

Cure Rare Disease’s Rich Horgan discusses the importance of preclinical NAbs screening and helping rare disease patients better understand their eligibility for gene therapies. Neutralising antibodies (NAbs) present a unique challenge to researchers looking to treat patients with AAV treatment. As AAV is a virus derived from the common cold, the immune system can easily have levels of pre-existing NAbs that will recognise and neutralise AAV, rendering it ineffective.

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Varenicline Clinical Pearls

Med Ed 101

Cigarette smoking is a difficult problem that pharmacists and other healthcare professionals can play an important role in. Varenicline is one of the main medications that can be used to help curb this addiction. In this post, I will lay out my most important varenicline clinical pearls that I have learned from my practice as […]. The post Varenicline Clinical Pearls appeared first on Med Ed 101.

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NIAID kicks off fourth iteration of COVID-19 trial

Outsourcing Pharma

The division of the National Institutes of Health has begun enrolling hospitalized patients in a trial investigating various potential COVID-19 treatments.

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Dupixent approved in EU for atopic dermatitis in children

Pharma Times

First biologic to be approved for children aged six to 11 years with condition

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The urgent need for education and awareness about mitochondrial disease

pharmaphorum

Delayed diagnosis, misdiagnosis, and no cure or disease modifying treatments – children living with mitochondrial disease face all the issues often associated with rare diseases. It’s a problem that Michelle Bamber, whose two little girls both have the life-limiting condition, knows only too well. Lily was a happy, contented baby, and her parents had no cause for concern until she went for her two-year check and was put on a pathway to diagnosis.

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Drugs That Worsen Urinary Incontinence

Med Ed 101

There are a few drugs that I remember when reviewing issues associated with urinary incontinence. Here’s my list of common drugs that worsen urinary incontinence. First, we must discuss the term incontinence. In general, it is a pretty vague term and can be associated with different medical processes. Incontinence simply means any involuntary or accidental […].

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Rare-disease foundation backs regenerative research

Outsourcing Pharma

CureDuchenne is investing in and collaborating with Mesentech, a company with a prodrug platform designed to selectively deliver therapeutics to bone.

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AbbVie partners with Frontier Medicines on protein degrader development

Pharma Times

Partnership will seek to develop small molecules for oncology/immunology targets

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Merck KGaA signs DNA damage response cancer deal with Artios Pharma

pharmaphorum

Germany’s Merck KGaA has joined with UK-based Artios Pharma in a potential multi-billion dollar deal to investigate novel DNA damage response targets in cancer. The principle of DNA damage response is already being exploited by AstraZeneca and other companies with their poly (ADP-ribose) polymerase (PARP) inhibitor drugs. These target the inherent genetic instability in certain cancer cells, which have switched to a backup mechanism to repair damage to their DNA code.

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J&J files lung cancer bispecific amivantamab for FDA approval

pharmaphorum

Johnson & Johnson has filed its bispecific antibody amivantamab to the FDA, hoping to muscle into the big market for drugs that are used to treat EGFR-positive non-small cell lung cancer (NSCLC). J&J’s Janssen unit is seeking approval of the drug in a specific patient group – those with exon 20 insertion mutations whose disease has progressed despite first-line chemotherapy.

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