Sat.Aug 17, 2024 - Fri.Aug 23, 2024

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Majority of Savings from CMS Price Negotiations Comes From 3 Drugs

Drug Topics

Research experts at the Brookings Institution in Washington, D.C., analyzed the savings estimates provided by CMS for its drug price negotiations and compared them with the institution’s own estimates.

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Pharmacy Focus: Alzheimer Drug Pipeline Expands, Promising Therapies in Development

Pharmacy Times

The Alzheimer disease treatment landscape is evolving with new FDA-approved antibody therapies and advancements in biomarker testing to enable earlier diagnosis and intervention.

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Opinion: Why you may not need a checkup every year

STAT

I’m a doctor and epidemiologist, so you might expect me to be religious about preventative care: yearly visits to my primary care physician, that sort of thing. But I know we can’t prevent most disease and a lot of what we do in medicine doesn’t add value and sometimes even causes harm. So instead, I practice a seemingly radical but necessary idea for getting the best from medicine while avoiding excesses.

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Epic touts new AI applications to streamline charting and bring research insights to the point of care

Fierce Healthcare

Health IT giant Epic is pushing ahead rapidly to build out artificial intelligence technologies and generative AI features in its electronic health record software. | The goal, according to Epic executives, is to ease the documentation burden for clinicians, streamline charting and coding and bring evidence-based medical insights and research right to doctors' fingertips at the point of care.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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APhA Campaign Aims to Spread Awareness About Harmful PBM Practices

Drug Topics

The American Pharmacists Association is dedicating further time and resources to its ongoing fight for federal PBM reform.

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Analysis Finds Bidirectional Association Between Asthma and Psoriasis

Pharmacy Times

The study authors recommend that health care professionals are aware of the connections, notably in adolescent patients and those with moderate to severe psoriasis.

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Bayer layoffs hit Switzerland with 150 cuts at Basel consumer health hub: reports

Fierce Pharma

Bayer’s latest round of layoffs has reportedly hit Basel, Switzerland, home of the international headquarters of the company's consumer health division. | The layoffs are the latest in Bayer's massive restructuring plan that has so far impacted more than 3,000 staffers since the start of the year.

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Pharmacy Deserts Prominent in Areas of High Social Vulnerability

Drug Topics

Researchers analyzed data from every county in the US and aimed to address the association between high social vulnerability and pharmacy deserts.

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Industry Voices—10 things every healthcare organization can do to defend against cyberattacks

Fierce Healthcare

The healthcare industry confronts a complex, double-barreled challenge as it tries to combat the recent deluge of dangerous and damaging cyberattacks. | Cyber resilience is the ability to recognize threats, respond to them, recover quickly and at scale. The clear goal: fending off attacks more efficiently, limiting damage and restoring normal operations with minimal impact to patients.

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Opinion: Doing more cancer screening won’t reduce Black-white health disparities

STAT

For years, Black Americans have been more likely to die of cancer than white Americans. There is a widespread belief that cancer screening — tests to detect hidden cancer — can reduce this Black-white disparity. While it is important to be attentive to racial disparities in health and health care, the belief in screening is misguided. More cancer screening primarily serves the interests of the health care system, not those of Black Americans.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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New study suggesting suicidal ideation risk for Novo's Ozempic adds to ongoing safety debate

Fierce Pharma

Regulators in both the U.S. and Europe have looked into the potential link between suicidal thoughts and Novo Nordisk’s blockbuster semaglutide franchise after reports sounded the alarm last year. | Researchers found that users of Novo's semaglutide who were logged in a WHO database were more likely to report suicidal ideation.

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Meat Consumption Linked with Higher Risk of Developing Type 2 Diabetes

Drug Topics

Increased incidence of typed 2 diabetes was associated with higher consumption of processed meat, unprocessed red meat, and poultry.

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NACDS President Discusses Themes, Highlights of Total Store Expo

Pharmacy Times

Steve Anderson, president and CEO of the National Association of Chain Drug Stores (NACDS), discusses memorable moments from this year's NACDS Total Store Expo.

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STAT+: AI in medicine: A national registry could help increase transparency, experts say

STAT

The use of artificial intelligence in hospitals is ramping up so fast — and with such little transparency — that it is impossible to track how any given product is impacting the cost or quality of care. Whether AI is monitored at all is entirely up to individual health systems.   “Everybody is doing this differently, and many health systems are not doing it,” said Mike Pencina, chief data scientist at Duke Health.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Lawmakers urge FDA to investigate clinical trials run in tandem with China's military

Fierce Pharma

As House lawmakers prepare for a September vote on the controversial BIOSECURE Act, the House Select Committee on the CCP is expanding the scope of its scrutiny on China's biopharma ecosystem. | As House lawmakers prepare for a September vote on the controversial BIOSECURE Act, the House Select Committee on the CCP is expanding the scope of its scrutiny on China's biopharma ecosystem.

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Q&A: Discussing the Dangers of Buying GLP-1s From Online Pharmacies

Drug Topics

Timothy Mackey, MAS, PhD, discusses a study that sought to determine the risk of sourcing semaglutide from online platforms.

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Employers embracing direct contracting and bypassing insurers: survey

Fierce Healthcare

Employers are actively seeking out alternatives to curb rising health benefit costs by sidestepping traditional carriers, a new report from Brighton Health Plan Solutions shows. | A new report highlights a business opportunity for providers and health systems to engage in direct contracting.

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STAT+: Tome Biosciences, once a high-flying gene-editing startup, is floundering

STAT

Buzzy gene-editing startup Tome Biosciences is floundering, just nine months after launching with $213 million in funding, according to several sources with direct knowledge of the matter. One person with knowledge of the situation told STAT that Tome is winding down operations altogether and seeking a buyer by Nov. 1. Another source reported that there are still options on the table to keep the biotech running.

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FDA weighs limiting PD-1 drugs in stomach cancer, calls on experts to discuss Merck, BMS and BeiGene meds

Fierce Pharma

The FDA is once again gathering external experts to scrutinize PD-1 inhibitors as a group. | The FDA will hold an advisory committee meeting on Sept. 26 to consider whether approvals for checkpoint inhibitors in advanced gastric and gastroesophageal junction (GEJ) adenocarcinoma—as well as in esophageal squamous cell carcinoma (ESCC)—should be restricted based on a tumor’s PD-L1 expression.

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Tirzepatide Demonstrates 94% Diabetes Reduction, 22% Weight Loss in SURMOUNT-1 Study

Drug Topics

A detailed report of study findings will be published in a peer-reviewed journal and presented at ObesityWeek 2024.

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Medicare Advantage's growth a bad omen for hospitals, S&P Global warns

Fierce Healthcare

The upward trajectory of Medicare Advantage (MA) enrollment is likely to become an issue for hospitals and other healthcare providers forced to contend with plans’ prior authorization requirements | Prior authorization burdens and "a challenging contract negotiation season" on the horizon are likely headwinds for providers, and hospitals in particular, according to a recent report.

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STAT+: U.K.’s cost-effectiveness agency gives negative review of Alzheimer’s drug Leqembi

STAT

LONDON — Leqembi, the Alzheimer’s treatment from Eisai and Biogen, has hit another roadblock reaching patients in Europe.  In draft guidance, the U.K.’s cost-effectiveness watchdog on Thursday said that the limited benefits of the drug, also called lecanemab , do not justify its costs, citing not just the price of the treatment but the related expenses of administering it and monitoring for side effects.

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Lilly adds to tirzepatide's impressive pedigree with new data showing the med helps stave off diabetes

Fierce Pharma

Already wildly popular in type 2 diabetes and obesity, Eli Lilly’s tirzepatide can help prevent one of the very diseases it’s meant to treat, new data show. | Already wildly popular in type 2 diabetes and obesity, Eli Lilly’s tirzepatide can help prevent one of the very diseases it’s meant to treat, new data show.

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Q&A: NACDS President and CEO on PBM Reform and Grassroots Advocacy

Drug Topics

The National Association of Chain Drug Stores is active at both the federal and state levels in advocating for PBM reform.

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CMS closes thousands of No Surprises Act complaints, directs $4M in relief

Fierce Healthcare

The Centers for Medicare & Medicaid Services (CMS) issued a new report Tuesday detailing total complaints related to the No Surprises Act and Affordable Care Act compliance. | A new CMS report outlines the types of No Surprises Act complaints resolved by the federal agency since June 30.

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Opinion: Mask bans disenfranchise millions of Americans with disabilities

STAT

Last week, a mask ban in Nassau County, New York was signed into law. If I lived just 60 miles east of my New Jersey town, I would be under threat of a fine or jail time every time I left the house. I’ve been masking consistently in public since 2020, when the Covid-19 pandemic began, because I have a kidney transplant and will take immunosuppressant medication for the rest of my life.

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FDA signs off on Modena, Pfizer/BioNTech's adapted vaccines to corral elusive COVID virus

Fierce Pharma

The FDA has authorized the use of | The FDA has authorized the use of new vaccines from Pfizer/BioNTech and Moderna which have been designed to defend against the Omicron KP.2 variant of SARS-CoV-2. The nod comes as word of a new omicron variant, KP.3.1.1, is beginning to eclipse KP.2 as the dominant strain of the virus in the United States.

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Disparities Hinder HPV Vaccine Goals in USAPI Jurisdictions

Drug Topics

Access inequities are preventing the US-affiliated Pacific Island (USAPI) jurisdictions from meeting the WHO 2030 goal of 90% human papillomavirus (HPV) vaccination series completion coverage.

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Employers are bracing for healthcare costs to spike in 2025. Here's why

Fierce Healthcare

Employers are up against escalating healthcare costs, driven by mounting prescription drug expenses, inflation and worsening chronic conditions, a new survey shows. | Employers are up against escalating healthcare costs, driven by mounting prescription drug expenses, inflation and worsening chronic conditions, a new survey shows.

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STAT+: Lilly’s Zepbound slashed risk of developing diabetes

STAT

Eli Lilly’s obesity drug Zepbound significantly cut the risk of developing type 2 diabetes, showing the benefits of long-term use of the blockbuster therapy. In a Phase 3 trial that lasted over three years, people with pre-diabetes taking Zepbound had a 93% lower risk of progressing to diabetes compared with people on placebo, Lilly said Tuesday.

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Targeting AZ's Tagrisso, Johnson & Johnson's Rybrevant combo wins key FDA nod in first-line lung cancer

Fierce Pharma

A new FDA approval has vaulted a Johnson & Johnson lung cancer drug combination into a key territory already dominated by AstraZeneca’s Tagrisso. | A new FDA approval has vaulted a Johnson & Johnson lung cancer drug combination into a key territory already dominated by AstraZeneca’s Tagrisso. But the real battle against the EGFR king has yet to start.

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Q&A: The Importance of Cooling Technology for Prescription Drugs

Drug Topics

Dana Krug, Senior Vice President of Cold Chain Fulfillment at Phononic, discussed the importance of cooling medications in the rising heat of the summer months.

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Steward Health Care must hold off on issuing closure notice for PA hospital, bankruptcy judge rules

Fierce Healthcare

A Thursday afternoon sale hearing scheduled for several Steward Health Care hospitals was shelved in favor of an amended bankruptcy court itinerary hashing out multiple disputes related to the comp | A busy day in bankruptcy court brought new updates on Steward Health Care's bids and closure plans for hospitals in Florida, Pennsylvania and Massachusetts.

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STAT+: Gene therapy pioneer Jim Wilson believes he can commercialize rare-disease drugs in a tough climate

STAT

If you’d told Jim Wilson three years ago that he’d be stepping down as director of the University of Pennsylvania’s storied Gene Therapy Program, he wouldn’t have believed you. And yet he’s now doing exactly that. Wilson, a gene therapy pioneer who has spent decades devising ways to deliver functional copies of missing or defective genes to patients, recently announced that he’s leaving Penn to found a pair of companies focused on developing gene therapi

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