Sat.Jul 27, 2024 - Fri.Aug 02, 2024

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Embracing Digital Transformation: How Pharmacies Can Thrive in an Evolving Health Care Landscape

Pharmacy Times

Pharmacies can adapt by embracing digital self-service options to better engage with patients, meet increasing consumer demand, and enhance revenue streams.

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CVS PBM to Pay $45 Million in Rebates to State of Illinois

Drug Topics

CVS Caremark and the State of Illinois settled a lawsuit due to the company’s failure to pay contracted rebates.

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Opinion: The coronavirus lab leak hypothesis is damaging science

STAT

Where and when the Covid-19 pandemic began — in Wuhan, China in late 2019 — is well known. How it began is a matter of heated controversy. There are two competing hypotheses, one of which is hindering the process of scientific discovery and could hold back the development of vaccines and other antiviral agents in the U.S. The zoonosis hypothesis proposes that SARS-CoV-2, the virus that causes Covid-19, was naturally transmitted from an animal to one or more humans in a so-called we

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Humana posts $679M in Q2 profit as it faces continued Medicare Advantage headwinds

Fierce Healthcare

Humana affirmed its guidance for the year as it continues to face headwinds in the Medicare Advantage (MA) space. | Humana affirmed its guidance for the year as it continues to face headwinds in the Medicare Advantage space.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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CDC Recommends International Travelers Receive MMR Vaccination 2 Weeks Prior to Travel

Pharmacy Times

The CDC says that even if travel is less than 2 weeks away, unvaccinated individuals should still receive a dose of the measles, mumps, and rubella vaccine for protection against the disease.

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Pancreatic Cancer Dendritic Cell Vaccine Receives FDA Fast Track Designation

Drug Topics

The technology from Diakonos Oncology initiates a natural immune response that targets and eliminates cancer cells by activating cytotoxic TH1 cell signaling pathways.

More Trending

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FDA signs off on Adaptimmune's Tecelra as the first engineered cell therapy for a solid tumor

Fierce Pharma

Adaptimmune has won accelerated FDA approval | Adaptimmune has won accelerated FDA approval for Tecelra (afami-cel), a treatment for metastatic or unresectable synovial sarcoma which becomes the first engineered cell therapy for a solid tumor and the first new treatment in the indication in more than a decade.

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Long-Acting Injectable Form of Cabotegravir Safe for HIV Prevention in Pregnant Cisgender Women

Pharmacy Times

An extension of a long-acting cabotegravir study shows safety prior to and during pregnancy in cisgender women, with full results being presented at the 2024 International AIDS Conference.

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FDA Warns Against Using At-Home Chemical Peels, Cites Retailers

Drug Topics

Pharmacists should be knowledgeable about the symptoms of chemical peel irritation to effectively advise patients.

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STAT+: Sarepta demanded Duchenne patient advocacy group censor video critical of the company

STAT

Sarepta Therapeutics demanded a prominent patient advocacy organization censor a video that contained pointed criticism of the company’s recently approved gene therapy for Duchenne muscular dystrophy, STAT has learned. The incident raises questions about the financial ties between Sarepta and the advocacy group, Parent Project Muscular Dystrophy, and whether the drugmaker uses its money to influence, or even muzzle, debate over its Duchenne medicines.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Nearly half of beneficiaries don't know the difference between Medicare and MA: survey

Fierce Healthcare

The U.S. healthcare system remains complex and inaccessible, leaving many seniors feeling uninformed, according to a new survey from digital health company DUOS. | Seniors are growing more comfortable with technology, but many still don't understand key differences between major health programs.

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Expert: The Definition of Alzheimer Disease is Shifting From Clinical to Biological

Pharmacy Times

Edward B. Lee, MD, PhD, also describes how understanding Alzheimer disease requires the integration of multiple fields including genetics, pathology, epidemiology, pharmacology, and physiology.

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Drug Topics Top 10: Most Read Stories From July 2024

Drug Topics

Check out this list of our top 10 most read stories from July 2024.

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STAT+: Mount Sinai mounted aggressive campaign to stifle debate over revelations about its controversial brain research

STAT

Mount Sinai, a leading hospital network in New York City, has mounted an extraordinary behind-the-scenes campaign to blunt the fallout over revelations about its controversial research project in which brain biopsies are taken from patients undergoing deep brain stimulation, STAT has learned. That has included not only enlisting its own patients to defend the research but also seeking to stop a professional society of neurosurgeons from issuing a statement that could have jeopardized the researc

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Ochsner Health going all-in on ambient AI, taps DeepScribe to deploy tech for 4,700 physicians

Fierce Healthcare

Ochsner Health is going all-in on ambient AI voice technology for its thousands of doctors and has inked an enterprise agreement to roll out DeepScribe's technology across its health system. | Ochsner Health inked an enterprise-wide agreement with DeepScribe to roll out its AI medical scribe across its 46-hospital system for 4,700 providers.

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Expert: Tau Oligomers Are a Culprit in the Spread of Alzheimer Disease Pathology

Pharmacy Times

Tara Spires-Jones, DPhil, FMedSci, discusses how oligomeric tau clumps inside brain synapses, pointing to indirect evidence that it may be progressing through the brain by jumping between connections.

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Immunization Roundup: Reducing Long COVID, Moderna Flu Vaccine, and More

Drug Topics

Catch up on important immunization news from the month of July.

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STAT+: Dental AI startup raises $30 million, including from Mark Zuckerberg’s dad

STAT

As the AI race in dentistry grows more heated, a startup called Perceptive is aiming to automate each stage of a dental visit, from imaging to treatment recommendations to the actual surgical procedure. The Boston startup, which recently came out of stealth mode, announced on Tuesday that it has received $30 million in funding to work on a dental system that includes a hand-held imaging machine, an AI algorithm to help diagnose and suggest treatment, and a surgical robot to complete the procedur

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CMS, HHS can use existing federal authority to regulate AI safety in hospitals: JAMA

Fierce Healthcare

As artificial intelligence rapidly makes inroads in healthcare, federal agencies already have the authority to regulator AI at the hospital bedside, according to some healthcare researche | An article published in JAMA Health Forum argues that through the conditions of participation in Medicare and Medicaid, CMS has the authority to oversee how hospitals are implementing AI into patient care.

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Pharmacy Focus - Oncology Edition: The Link Between Gut Health and Colon Cancer, Exploring the Wellness Innovation Network

Pharmacy Times

Jennifer Dunphy, DrPH, MBA, MPH and Nelly Awkar-Lazo, MD, discuss the rise in young-onset cancer, the gut-colon cancer link, and the importance of healthy lifestyle choices for cancer prevention.

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Vertex lifts sales guidance as launch of gene therapy Casgevy picks up steam

Fierce Pharma

As growth in Vertex's cystic fibrosis portfolio buoys the company amid the launch of gene therapy Casgevy, the company is feeling confident enough to boost its revenue outlook for the year. | As of mid-July, around 20 patients completed the first step of Casgevy treatment by having their cells collected, up from five patients during the first quarter.

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Could cow vaccines help halt the spread of bird flu in U.S. herds? Experts are divided

STAT

With the number of U.S. dairy herds infected with H5N1 bird flu rising almost daily, fears are growing that the dangerous virus cannot be driven out of this species. That belief is amplifying calls for the development of flu shots for cows. Multiple animal vaccine manufacturers are reportedly at work trying to develop such products. And the U.S. Department of Agriculture is eagerly encouraging the effort, detailing in a notice last week what kinds of evidence would be needed to win licensing app

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Teladoc posts $838M loss in Q2, lays out BetterHelp strategic pivot

Fierce Healthcare

In its first quarter with new CEO Chuck Divita, national telehealth provider Teladoc Health posted a net loss of $838 million in Q2 that included a nearly $800 million impairment charge a | Teladoc said on its earnings call on Wednesday that challenges with BetterHelp and increasing advertising costs led its revenue to decline in Q2.

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FDA Approves Benzgalantamine for Treatment of Alzheimer Disease

Pharmacy Times

Benzgalantamine (Zunveyl; Alpha Cognition) is a cholinesterase inhibitor indicated for the treatment of mild-to-moderate dementia in adults.

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Eco HPLC-based method shows promise for Z-alkene synthesis

European Pharmaceutical Review

Japanese researchers have developed a new method for photoisomerisation of E -cinnamamides to Z -cinnamamides. The approach uses a recycling photoreactor coupled with a high-performance liquid chromatography (HPLC) system. As organic compounds, many Z -alkenes “cannot be prepared through conventional methods involving thermodynamic methods”. On the other hand, “photoisomerisation can offer good yields”, they noted.

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STAT+: In a big step for liquid biopsy, FDA approves a blood test for colorectal cancer

STAT

The Food and Drug Administration on Monday approved a blood test intended to detect colon cancer, a product many experts hope will help catch cases of the disease early enough so that they can be more easily treated. The test, called Shield and made by Guardant Health, a Palo Alto, Calif.-based biotech firm, comes with a drawback: It is not as good as a colonoscopy and other tests at detecting precancerous or early stage cancers.

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CVS Health now tracks extreme heat to warn at-risk patients with personalized resources

Fierce Healthcare

CVS Health has launched an environmental health impact program to help vulnerable Americans during extreme weather events. | Using advanced environmental data analytics and patients' medical and pharmacy data, CVS Health offers timely excessive heat alerts and outreach to at-risk patients up to a week before the event.

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2-Drug Regimen Shows Comparable Effectiveness With 3-Drug Regimen to Treat HIV-1

Pharmacy Times

Dolutegravir/lamivudine was non-inferior to bictegravir/emtricitabine/tenofovir alafenamide fumarate, meeting the study’s primary end point.

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Bayer lops off 70 more employees at New Jersey headquarters

Fierce Pharma

Four months after Bayer handed pink slips to 90 staffers at its U.S. headquarters in Whippany, New Jersey, the company is laying off 70 more workers at the site. | Four months after Bayer handed pink slips to 90 staffers at its U.S. headquarters in Whippany, New Jersey, the company is laying off 70 more at the site, according to a state Worker Adjustment and Retraining Notification.

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CDC will offer seasonal flu shots to farmworkers to lower bird flu risk

STAT

The Centers for Disease Control and Prevention announced Tuesday that it is funding a $5 million program to vaccinate livestock industry workers against seasonal flu in a bid to reduce the pandemic risk posed by the ongoing H5N1 bird flu outbreak in cattle. The voluntary program, which will be administered by state and local public health workers, is aimed at getting seasonal flu shots into as many people as possible who are working in proximity to animals — poultry, cows, or other livest

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L.A. Care tasks social workers to serve unhoused population

Fierce Healthcare

There are 75,000 homeless people in Los Angeles County, a county that is the size of Delaware and Rhode Island combined and has a population that is larger than 40 states. | L.A. Care Health Plan is sending social workers to temporary housing sites in Los Angeles County to find more permanent housing solutions.

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St. John’s Wort Could Show Benefit in Major Depressive Disorder

Pharmacy Times

Patients with MDD may also seek complementary or alternative therapies in the form of dietary supplements which might be perceived by patients to be natural and safer than medicinal agents.

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Rainwater Foundation, CurePSP, Aging Mind Foundation fund innovative tauopathy research

Outsourcing Pharma

The Rainwater Charitable Foundation (RCF), in collaboration with CurePSP and the Aging Mind Foundation (AMF), has announced the allocation of $2 million in grants to support groundbreaking research in primary tauopathies.

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STAT+: Older GLP-1 drug may help protect brains of Alzheimer’s patients, early study suggests

STAT

A new study suggests that an older GLP-1 drug may help protect the brains of people with early Alzheimer’s disease, supporting the case for further research on the class of medications — originally developed for obesity and diabetes — in neurological diseases. The Phase 2 randomized trial, led by researchers at Imperial College London, tested Novo Nordisk’s liraglutide, the predecessor to Ozempic and Wegovy, in patients with early Alzheimer’s disease over one y

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