Sat.Dec 09, 2023 - Fri.Dec 15, 2023

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Opinion: Listen: When do tests hurt more than help?

STAT

Manil Suri and Daniel Morgan are an unusual team: Manil is a mathematics professor and author (of both fiction and nonfiction ), while Daniel is a physician and professor of epidemiology, public health, and infectious diseases. But — in what they say is a typical “Smalltimore” moment — both a neighbor and a student had told them they should work together because of a shared interest in false positives on diagnostics tests.

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Five Ways Preceptors May Integrate Generative Artificial Intelligence Programs Into Pharmacy Education Learning Experiences

IDStewardship

In this article a clinical pharmacist discusses ways that preceptors may integrate generative artificial intelligence programs into pharmacy education for student and resident learning experiences. Authored By: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Generative artificial intelligence was NOT used to create this text. Although, maybe it would be better if I had used it!

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FDA Approves First Gene Therapies for Treatment in Patients With Sickle Cell Disease

Drug Topics

The approvals mark a turning point in the ongoing effort to manage sickle cell disease, the most common inherited red blood cell disorder in the United States.

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From Fear to Passion: Embracing the Unexpected Journey into Pediatric Pharmacy with Dr. Stephen Small!

Pharmacy Is Right For Me

An Unexpected Path Deciding exactly what you want to do or where you want to go in life is difficult. What if you don’t like where you end up? What if you change your mind? Dr. Stephen Small is a prime example of what it looks like to not only change your mind but to embrace the unexpected. Dr. Small is a pediatric clinical pharmacist specialist but if you had asked him years earlier, he would not have thought that he would end up working with children, “Pediatrics was actually the only specialt

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Study: Stem Cell Therapy Shows Improvement in QoL for Those With Heart Failure

Pharmacy Times

Investigators also found that the results demonstrated lower death and hospitalization rates for those with advanced heart failure treated with cell therapy.

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Done deal: Pfizer completes $43B acquisition of Seagen, doubling its oncology pipeline

Fierce Pharma

Pfizer’s $43 billion acquisition of Seagen is in the books, the company said on Thursda | It’s a done deal. Pfizer’s $43 billion acquisition of Seagen is in the books, as it becomes the largest M&A transaction in the biopharma industry since AbbVie snatched up Allergan for $63 billion in 2019. The buyout of the antibody-drug conjugate specialist has doubled Pfizer’s pipeline to 60 programs.

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Gene therapy offered this 7-year-old freedom. The price: a grueling year

STAT

PHILADELPHIA — The meds Shelby Campbell needed for her rare blood disorder stopped working just after her sixth birthday. She lost her appetite and was often doubled over in pain. She continued getting blood transfusions but her doctors struggled to manage side effects that threatened her organs. By the time she turned 7, the doctors told her parents they had to do something — soon.

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Pharmacy Automation Can Be a Means to Drug Safety

Pharmacy Times

In the pharmacy, time is the ultimate value-add.

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Pfizer warns of further sales decline for COVID products, plots $500M in additional cost cuts

Fierce Pharma

Using Tuesday to announce good news—that its $43 billion acquisition of Seagen would be | Using Tuesday to announce good news—that its $43 billion acquisition of Seagen would be finalized on Thursday—Pfizer sandwiched its bad news, which came on Wednesday with its 2024 guidance. The company expects revenue to reach between $58.5 billion and $61.5 billion next year, coming up short of the analyst consensus of $63.2 billion, largely because of the plummeting demand for its COVID-19 products.

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Daratumumab Plus VRd Improves Progression Free Survival in Newly Diagnosed Multiple Myeloma

Drug Topics

Results of the phase 3 PERSEUS study were presented at the 2023 ASH Annual Meeting and Exposition.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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NIH panel calls for fewer, better-paid postdocs in bid to halt loss of scientists to industry

STAT

A National Institutes of Health working group on Friday recommended a sizable increase in salaries of postdoctoral researchers and a cap on the length of the position in an effort to secure the future of academia’s research workforce amid an unprecedented exodus of young life scientists to industry. The group called for raising minimum postdoc salaries to $70,000 beginning next year — an increase of more than 20% — and adjusting wages for annual inflation, as well as limitin

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Litfulo From Pfizer Inc

Pharmacy Times

The approval carries the limitation that ritlecitinib should not be used in combination with biologic immunomodulators, cyclosporine, other Janus kinase inhibitors, or other potent immunosuppressants.

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Europe names hundreds of critical medicines in quest to counter drug shortages

Fierce Pharma

Over the past several years, drug shortages have vexed doctors and patients on both sides of the Atlantic, prompting lawmakers and government agencies to take action in both Europe and the U.S. | Tuesday, the European Medicines Agency laid out a list of more than 300 critical generic drugs that could fall prey to future shortages. Inclusion in the list doesn’t mean a particular drug is likely to experience a shortage anytime soon, the EMA said.

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CDC: Vaccine Coverage for Respiratory Viruses Needs to Increase

Drug Topics

Immunizations against influenza, COVID-19, and RSV are lower than they were this time last year, and hospitalizations have increased across all age groups.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Humana used algorithm in ‘fraudulent scheme’ to deny care to Medicare Advantage patients, lawsuit alleges

STAT

Medicare Advantage beneficiaries on Tuesday filed a class-action lawsuit alleging that the health insurance giant Humana illegally used an algorithm to prematurely cut off payment for rehabilitation care after patients suffered serious illnesses and injuries. The suit, filed in U.S. District Court in Western Kentucky, argues Humana’s reliance on the algorithm, known as nH Predict, was part of a fraudulent scheme to reap a windfall by systematically denying claims to desperately ill people

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Alternative Funding Programs Affect Our Most Vulnerable Patient Populations

Pharmacy Times

AFPs limit access to provider-prescribed specialty medications.

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Fees charged by hospitals for colonoscopy procedures 50% higher than surgical centers, study finds

Fierce Healthcare

A new price comparison study finds over 50% higher facility fees for commercially insured colonoscopies performed in hospitals rather than ambulatory surgery centers (ASCs), suggesting that “money | The analysis of commercial payers' price transparency data shows that “money has apparently been left on the table” for employers and consumers, the study's senior author says.

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Mediterranean Diet Could Help Reduce Adverse Pregnancy Outcomes

Drug Topics

The mediterranean diet targets inflammation, oxidative stress, and hormonal balance mechanisms, which are also associated with female reproductive outcomes.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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House passes site-neutral policy, transparency, PBM reform package

STAT

WASHINGTON — The House passed a relatively major health care package late Monday, an end-of-year victory after the same policies had to be yanked from consideration in September because they lacked bipartisan support. Though the package is unlikely to pass the Senate and become law as-is, its advancing through the House does make each included policy more attractive for a potential government funding deal, as lawmakers draw closer to the Jan. 19 deadline to fund the government and extend

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Golidocitinib Demonstrates Significant Survival Benefits For Patients with Peripheral T-cell Lymphoma

Pharmacy Times

Median overall survival is set to be more than 2 years, which is more than double the overall survival of current frontline therapies.

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House price transparency legislation passes with bipartisan support

Fierce Healthcare

The Lower Costs, More Transparency Act, which advances policies to force pharmacy benefit managers and hospitals to meet price transparency standards, passed on the House floor Monday by a vote of | Members on both sides of the aisle are celebrating successful efforts to codify price transparency requirements and establish site-neutral payments in the Lower Costs, More Transparency Act passed by the House of Representatives on Monday.

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MAPS Submits NDA for First-Ever Psychedelic-Assisted Therapy for PTSD

Drug Topics

Despite affecting 13 million Americans annually, existing post-traumatic stress disorder (PTSD) treatments offer modest relief and more effective approaches are needed.

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Opinion: U.S. medical schools aren’t teaching future doctors about 7.4 million of their patients

STAT

Oliver McGowan was 18 years old when he was hospitalized in England with recurrent seizures and pneumonia. He was autistic, and he and his parents had one specific request for the medical team: no antipsychotic medications. When he had taken them in the past, they made his seizures worse and had devastating effects on his mood. Despite the family’s vehement protests, doctors gave him an antipsychotic.

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Moderate Intensity Exercise May Improve Cognition Following a Night of Poor Sleep

Pharmacy Times

Moderate cycling improved cognitive function in patients who got partial or no sleep.

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Class action lawsuit accuses Humana of using AI algorithms to restrict access to care

Fierce Healthcare

A newly filed lawsuit alleges that Humana used artificial intelligence algorithms to deny key rehabilitation care for seniors. | A newly filed lawsuit alleges that Humana used artificial intelligence algorithms to deny key rehabilitation care for seniors.

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Combined Influenza, COVID-19 Vaccines Offer Strongest Protection for Children

Drug Topics

While either vaccine offers some protection, having both vaccines offers the strongest level of protection against hospitalization and severe complications like MIS-C, and death.

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STAT+: With big ambition — and a family name to match — Reed Jobs charts his own course in biotech

STAT

In the months after his father died of complications from pancreatic cancer, Reed Jobs found it difficult to go back to life as it was before. He was a sophomore studying biology at Stanford University and, up until October 2011, had always planned to pursue a career in cancer research. His father had been diagnosed when he was a preteen and he had spent much of his adolescence thinking about treatments and clinical trials, like many people whose parents are diagnosed with the disease during the

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Researchers Find Allergy Medication Could Aid Treatment for Lung Cancer

Pharmacy Times

Immune cells in lung cancer are connected to allergic conditions found in eczema and asthma.

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Study suggests PBMs are gaming pharmacy system to overcharge for drugs

PharmaVoice

Markups for generics can be as high as 7,000%, the researchers said.

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Google unveils MedLM generative AI models for healthcare with HCA, Augmedix and BenchSci as early testers

Fierce Healthcare

Google continues to advance its generative AI models designed specifically for healthcare use cases. | Google this week unveiled MedLM, a family of foundation models designed for healthcare industry use cases and available through Google Cloud.

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Methadone clinics spar with addiction doctors on bill that would widen access

STAT

Lawmakers on Tuesday will debate an addiction medicine proposal that would have been considered unthinkable just years ago: giving a select group of doctors the power to prescribe methadone directly to patients. With no end in sight to the deadly U.S. drug overdose crisis, which claims nearly 110,000 lives a year, many advocates have zeroed in on methadone as a potential game changer.

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MAPS PBC Submits NDA to the FDA for MDMA-Assisted Therapy for PTSD

Pharmacy Times

An FDA approval of 3,4-Methylenedioxy-methamphetamine (MDMA)–assisted therapy would require the Drug Enforcement Administration to reschedule MDMA in acknowledgement of its medical use, making it available for prescription medical use.

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Arcutis' Zoryve bags 2nd FDA nod, this time as a foam to treat 'the great neglected disease in dermatology'

Fierce Pharma

About a year after Arcutis Biotherapeutics unveiled positive data on roflumilast foam at the European Academy of Dermatology and Venereology congress 2022, the company has clinched a second FDA OK. | About a year after Arcutis Biotherapeutics unveiled positive data on roflumilast foam at the European Academy of Dermatology and Venereology congress 2022, the company has clinched a second FDA OK.

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