Sat.Aug 31, 2024 - Fri.Sep 06, 2024

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FDA Clears New Disposable Insulin Patch Pump For Patients With T1D and T2D

Drug Topics

Embecta’s new patch pump offers a larger insulin reservoir to better accommodate for the needs of patients with type 2 diabetes (T2D).

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Missouri resident who had no contact with animals tests positive for bird flu

STAT

This is a developing story and will be updated. A person in Missouri who didn’t report any contact with animals has tested positive for H5 bird flu, the state’s Department of Health and Senior Services and the Centers for Disease Control and Prevention said Friday. It’s not yet clear if the person was infected with the same virus strain that’s causing the ongoing outbreak among dairy cattle.

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AstraZeneca staffers detained in China over patient data collection, drug imports: Bloomberg

Fierce Pharma

AstraZeneca has found its employees’ practices under the microscope of Chinese law enforcement years after an insurance fraud case. | AstraZeneca has found its employees’ practices under the microscope of Chinese law enforcement years after an insurance fraud case.

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New Perspectives in CML Management: Personalized Approaches and Adaptive Strategies

Pharmacy Times

Optimizing outcomes for patients with chronic myeloid leukemia (CML) requires personalized treatment, adaptive dosing, and precise genetic insights.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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NCPA Calls on CMS to Establish PBM Protection for Independent Pharmacies

Drug Topics

As Medicare open enrollment begins, the NCPA is urging CMS to facilitate appropriate PBM contracting for pharmacies in the upcoming plan year.

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In a first, living mice are made transparent

STAT

When a dye called tartrazine is added to food, it creates a bright yellow hue often associated with lemon-flavored candy. But when mixed with a little water and daubed on the skin of mice, the dye makes their skin nearly transparent.  Researchers reported the new use for the common food dye today in the journal Science. The technique creates a fresh opportunity for researchers to understand what is going on under the skin of a live animal, which could eventually allow them to study the inne

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IVIG Shows Promise as Therapy in Patients With Recurrent Implantation Failure

Pharmacy Times

Intravenous immunoglobulin (IVIG) therapy was found to have statistically significant positive effects on live birth rates, implantation rate, and other indicators.

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FDA Clears First Digital Therapeutic for Treatment of Generalized Anxiety Disorder

Drug Topics

DaylightRX from Big Health is a digital formulation of cognitive behavioral therapy and is available by prescription only.

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Trying to time your seasonal vaccines just right? There are no easy answers, but here are some factors to consider

STAT

With fall coming into view, public health officials across the country are turning to the annual task of persuading legions of Americans to get vaccinated against some combination of influenza, Covid-19, and respiratory syncytial virus, three bugs that sicken mass numbers of people over the winter months, often overwhelming hospitals and health care delivery in the process.

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American Medical Association slams pay cut, G-codes in proposed Medicare pay rule for doctors

Fierce Healthcare

In its comments to the Centers for Medicare and Medicaid Services (CMS) on the draft CY2025 Medicare physician fee schedule (PFS), the American Medical Association badgered CMS on its pro | The American Medical Association submitted its comment letter to CMS on its draft CY2025 Medicare physician fee schedule. At issue was the 2.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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CDC Recommends Preventative Action Amid Rising Cases of West Nile Virus

Pharmacy Times

Cases have been detected in 33 US states so far this year, and the virus has recently hospitalized the former Chief Medical Advisor to the President of the US Anthony Fauci.

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Abbott’s OTC Lingo CGM for Wellness Now Available

Drug Topics

Lingo offers users a real-time glucose graph, a metric to track glucose spikes, food and activity logging, personal recommendations, and challenges to motivate healthy behaviors.

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Doctors use problematic race-based algorithms to guide care every day. Why are they so hard to change?

STAT

Pediatrician Alexandra Epee-Bounya had had enough. In her 20 years caring for children in Boston, she had seen hundreds of kids with suspected urinary tract infections. Each time, she’d turn to a calculator, used by all Boston Children’s Hospital clinicians, to judge the youngest childrens’ risk. Did the infant have a high fever?

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Providers, vendors building health AI have 'shared responsibility' to ensure safe adoption industrywide

Fierce Healthcare

BOSTON—There’s no shortage of providers and vendors working to develop and deploy artificial intelligence in healthcare—but not all who are delivering care are in a position to make use of these no | Healthcare AI has a tough battle on adoption, trust and responsible use, particularly among organizations lacking in-house tech expertise. Whether it's a vendor or another health system, stakeholders must be prepared to help their peers along the way, experts say.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Key Strategies Released for Integrating Equity Into Health Technology Assessment

Pharmacy Times

The Center for Innovation & Value Research has released a final report recommending strategies to ensure health equity is integrated into health technology assessment, which can influence drug pricing and selection by payers, as well as patient access to drugs.

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FDA Roundup: Novavax COVID-19 Vaccine, First Digital Therapeutic for GAD

Drug Topics

Check out important updates from the FDA for the week of September 2.

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Opinion: Letting funding for the All of Us research program lapse will cost the U.S. far more than it saves

STAT

I was in high school when I first encountered the ruthlessness of the number one killer in the U.S. A close friend of mine, then only 16 years old, witnessed his father having a heart attack while checking the mail. Despite desperate attempts at CPR on the driveway, he wasn’t able to save his dad, a seemingly healthy man in his early 40s. That event put me on a path to become a cardiologist.

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Humana exiting Medicare Advantage in 13 markets

Fierce Healthcare

Humana reaffirmed its full-year guidance but is leaving 13 Medicare Advantage (MA) markets next year, Chief Financial Officer Susan Diamond said during the Wells Fargo Healthcare Conference on Wedn | Humana is pulling back from Medicare Advantage markets and cutting benefits next year. The insurer expects it will lose thousands of members and supplemental benefit utilization will be high toward the end of this year.

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Insurance Status, Survival Outcomes Linked in Patients With Diffuse Large B-Cell Lymphoma

Pharmacy Times

Patients with DLBCL on Medicaid had worse survival outcomes than those on commercial insurance, but there were no statistically significant differences in survival between races.

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The Unyielding Grip of Fentanyl on America's Streets: A Pharmacist's Perspective

Drug Topics

Independent pharmacists, health care providers, community leaders, and law enforcement must all work together to address the fentanyl epidemic.

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STAT+: Diagnosed with cancer, a pharmaceutical executive became a patient advocate and changed drug development. It took decades

STAT

Kathy Giusti was diagnosed with multiple myeloma in 1996, when she was a 37-year-old executive at the drug company G.D. Searle. She was told she had three years to live. Twenty-eight years later, Giusti, 65, is thriving. One reason is the patient advocacy group she founded in 1998: the Multiple Myeloma Research Foundation. The group has raised more than $600 million for research, launched nearly 100 clinical trials, and helped bring more than 15 new drugs to market.

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Thatch secures $38M, backed by a16z and General Catalyst, to expand ICHRA benefits

Fierce Healthcare

Thatch wants to turn the traditional approach to health insurance on its head. | Thatch wants to turn the traditional approach to health insurance on its head. The company secured $38 million, backed by a16z and General Catalyst, to scale up its technology and fuel its growth.

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Tolebrutinib Shows Reduction in Disability Accumulation in Non-Relapsing Secondary Progressive Multiple Sclerosis

Pharmacy Times

In a promising development in multiple sclerosis research, tolebrutinib delayed the onset of disability progression in patients with nrSPMS.

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C Difficile Treatment Shows Positive Results in Phase 2 Study

Drug Topics

CRS3123 is a novel, small molecule, antibiotic drug candidate that selectively inhibits 1 form of the bacterial methionyl-tRNA synthetase enzyme and is not affected by resistance to any existing classes of antibiotics.

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Moderna reports encouraging results on its mpox vaccine, as outbreaks in Africa spread

STAT

The emergence of a second mpox outbreak in which the virus is spreading from person-to-person, as well as a sharp increase in overall cases of the disease in several African countries, is straining the world’s capacity to make and distribute vaccine to battle the threat. New options are needed, and a study published Wednesday suggests another may be on the horizon.

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The Life Sciences Generative AI Council and a sustainable technological future

pharmaphorum

Listen to the podcast interview with Manny Belabe from ArisGlobal as he discusses The Life Sciences Generative AI Council and its role in creating a sustainable technological future. Gain insights into the future of AI in life sciences.

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Navigating Multiple Myeloma Care: Balancing CAR T-Cell Therapy and Immunotherapy

Pharmacy Times

The evolving treatment landscape for multiple myeloma includes debates on the timing and effectiveness of CAR T-cell therapy and quadruple immunotherapy regimens.

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Community Pharmacist-Led Intervention for Victims of Domestic Abuse, Suicidal Ideation

Drug Topics

Researchers analyzed a co-developed pharmacy-based intervention for individuals who have experienced domestic abuse or suicidal ideation.

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STAT+: Vor Biopharma’s ‘shielded’ transplant delays relapse in leukemia patients

STAT

A CRISPR-augmented stem cell transplant that protects healthy cells from the toxic effects of anti-cancer medicines has shown preliminary evidence that it can delay relapse in patients with an aggressive form of leukemia, its maker Vor Biopharma said Thursday.  In the early stage study, eight of 10 patients with high-risk acute myeloid leukemia remain in remission after receiving a transplant with the Vor therapy, called trem-cel, followed by maintenance treatment with intensified doses of

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New Mountain Capital merges Apixio, Varis and The Rawlings Group in $3B deal

Fierce Healthcare

Private equity firm New Mountain Capital merged three health tech companies in a multi-billion dollar deal to be a top player in the payment integrity market. | Private equity firm New Mountain Capital merged three health tech companies in a multi-billion dollar deal to be a top player in the payment integrity market.

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Women Who Receive False Positive Mammography Results Are Less Likely to Attend Follow-Up Screenings

Pharmacy Times

The authors stress that health care providers should explain false positive results to their patients, reassure them that results may be negative, and stress the significance of continued screenings.

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Major Drug Distributors to Pay $300 Million in Opioid Epidemic Settlements

Drug Topics

McKesson, Cardinal Health, and Cencora will share the settlement payment, resolving claims that the companies were significantly involved in fueling the US opioid epidemic.

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Upending a longstanding paradigm, cardiologists embrace ZIP codes, not race, to predict heart risk

STAT

N ot only is Joseph Wright a physician, he’s the chief health equity officer for the American Academy of Pediatrics. So he was skeptical when, at his annual checkup in January, an alert popped up on his doctor’s computer screen. A calculator embedded in Wright’s health record had automatically pulled in his data, including the blood test he had done that morning.

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Out-of-pocket spending on prescriptions grew even after accounting for rebates: study

Fierce Healthcare

There's no shortage of attention on rising pharmaceutical costs, but policymakers need to have the full picture of trends in this space to work off of, according to a new study. | There's no shortage of attention on rising pharmaceutical costs, but policymakers need to have the full picture of trends in this space to work off of, according to a new study.

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