December, 2024

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It’s Time to Staunch Our Self-Inflicted Wounds

Drug Topics

Outside forces are at play, but pharmacists must turn inward to address some challenges in their profession.

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Study: Shingles Could Significantly Increase Risk of Dementia and Parkinson Disease

Pharmacy Times

Researchers recommend early vaccination against herpes zoster to mitigate the risks.

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Opinion: The DEA’s 2025 quotas for opioids will leave seriously ill patients in pain

STAT

A woman sat in our emergency department in agonizing pain, feeling shaky, nauseous, and weak — drug withdrawal was setting in. But she wasn’t a “junkie” or even a recreational drug user. She was in her mid-60s with advanced cancer in her ovaries that had spread to her abdomen, causing unbearable pain. She was my patient — let’s call her Teresa.

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Congress' end of year health deal may be falling apart

Fierce Healthcare

It still needs to pass, but an end-of-year package for healthcare is looking probable. The legislation includes PBM reform, telehealth extensions and more.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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RFK Jr. could 'cost lives in this country' if he pursues changes to US vaccine policy, Gottlieb says

Fierce Pharma

Robert F. Kennedy Jr.’s appointment last month to lead the U.S. Department of Health and Human Services immediately sent waves of speculation swirling throughout the biopharma industry. | The former FDA Commissioner pointed to the threat of measles if vaccination rates were to decline by 5%.

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Peculiar Articles: 10 Potential Conversation Starters From The Medical Literature

IDStewardship

In this posta list of peculiar journal articles are highlighted, which may serve as conversationstarters from the medical literature. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Social events like holiday parties or kids birthday parties can be unpredictable. Sometimes you know everyone and it is a lot of fun. Sometimes you do not know many people and you are stuck trying to make conversation with new acquaintances.

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Advancing Lung Cancer Treatment With Bispecific Antibodies: A Review of Amivantamab and Tarlatamab

Pharmacy Times

Bispecific antibodies amivantamab and tarlatamab hold promise for patients.

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‘I want help’: Behind bars, pleas for addiction medications often go nowhere

STAT

James Mannion knew what he needed. For nine months, while incarcerated in a county jail in Portland, Maine, he pleaded for a medication called buprenorphine. Mannion, a barber, recreational fisherman, and father of two, was once a regular heroin user, but had used the medication to eliminate the cravings and withdrawal he experienced whenever he tried to quit opioids cold turkey.

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Legislators urge DOJ to investigate PBMs for potential role in opioid epidemic

Fierce Healthcare

A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic. | A group of legislators is calling on the Department of Justice to dig into whether pharmacy benefit managers played a role in the opioid epidemic.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Five Lessons Learned About Antimicrobial Stewardship Metrics

IDStewardship

In this article an experienced antimicrobial stewardship pharmacist discusses lessons learned from navigating antimicrobial stewardship metrics. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article posted 13 December 2024 If you cannot measure it, you cannot determine if you have changedit. Antimicrobial stewardship metrics are essential for identifying, acting on, and re-evaluating opportunities to enhance the safe and appropriateuse of antibiotics.

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PBM Reform Pulled Back in Late Change to Spending Package

Drug Topics

With pressure from the House GOP, expected PBM reform was not included in Congress end-of-year spending package.

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Patients With Post-COVID POTS Experience Disruptions in Circadian Blood Pressure Rhythm Regulation

Pharmacy Times

Postural orthostatic tachycardia syndrome (POTS) diagnoses have greatly increased following the COVID-19 pandemic.

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Opinion: Extending Medicare coverage to obesity medications is imperative

STAT

Although bipartisan legislation to provide Medicare coverage for obesity treatments has circulated in Congress for more than a decade, the Congressional Budget Office (CBO) ventured to  estimate  the budgetary effects of such a policy for older Americans starting in 2026 for the very first time in a report published in October.  The CBO should be commended for conducting this comprehensive analysis.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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UnitedHealthcare CEO Brian Thompson fatally shot in Manhattan: reports

Fierce Healthcare

UnitedHealth Group abruptly ended its investor day event on Wednesday morning as new reports surfaced that the CEO of its health plan division had been fatally shot. | UnitedHealth Group abruptly ended its investor day event on Wednesday morning as news reports surfaced that the CEO of its health plan division had been fatally shot.

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Deadline looms for post-Brexit label changes for UK meds

pharmaphorum

The MHRA has reminded pharma companies that from 1st January all medicines sold in the UK will have to comply with new labelling requirements

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FDA issues warnings to GLP-1 compounders

The Checkup by Singlecare

Originally approved to help people with Type 2 diabetes, the class of medications known as GLP-1 agonists and dual GIP/GLP-1s quickly acquired a reputation for helping people shed stubborn pounds. As a result, the use of medications like Ozempic , Wegovy , Zepbound , Rybelsus , and Mounjaro has skyrocketed, as people turned to these medications to help them lose weightcausing drug shortages and creating a market for compounded versions of these brand-name drugs.

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Obesity: Most Read Stories From 2024

Drug Topics

Check out this list of our top 5 most read obesity stories from the year 2024.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA Approves First Generic of Liraglutide Injection to Lower Blood Sugar in Patients With Type 2 Diabetes

Pharmacy Times

The approval of the generic to liraglutide injection, currently in shortage, could help increase patient access to the type 2 diabetes treatment.

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CDC finds no evidence of bird flu virus in California toddler

STAT

Testing of samples taken from a child in California thought to have contracted H5N1 bird flu after drinking raw milk turned up no evidence of influenza viruses, the Centers for Disease Control and Prevention said Thursday.  A test run on a sample from the child — who went to a Marin County emergency department last week with a fever and vomiting — had been positive there for flu A.

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DOJ sues CVS, alleging it knowingly filled unlawful opioid prescriptions

Fierce Healthcare

The Justice Department has filed suit against CVS, alleging that the retail giant unlawfully dispensed opioid prescriptions. | The Justice Department has filed suit against CVS, alleging that the retail giant unlawfully dispensed opioid prescriptions.

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Reprieve for Chinese biotechs as BIOSECURE Act left out of key bill

Pharmaceutical Technology

Shares in WuXi AppTec, one of those implicated in the Chinese biotech blacklisting legislation, surged following the omission.

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Does Mounjaro need to be refrigerated?

The Checkup by Singlecare

Like semaglutide, Mounjaro (tirzepatide) is a once-a-week injectable medication that is FDA approved for helping manage blood sugar levels in those with Type 2 diabetes. It mimics two gastrointestinal hormones: glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). So, the active ingredient can also be prescribed for weight loss or obesity, combined with diet and exercise, under its licensed brand name Zepbound.

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Infectious Disease: Most Read Stories From 2024

Drug Topics

Check out this list of our top 5 most read infectious disease stories from the year 2024.

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ASH 2024: Zanubrutinib Monotherapy, With Obinutuzimab Demonstrates Durable Efficacy and Safety in CLL/SLL

Pharmacy Times

Constantine Tam, MD, discusses zanubrutinib's efficacy in CLL/SLL, emphasizing its durability, high response rates, safety considerations, and evolving therapeutic potential in combination with other agents.

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Gilead to test once-a-year HIV prevention shot

STAT

Gilead said Tuesday that it will soon begin Phase 3 testing for a drug it believes could prevent HIV infection with just a single shot every year. Such a medicine, if proven effective, would be the closest thing to a vaccine the HIV field has produced in four decades of research. The company plans to begin the trial next year, with an eye toward regulatory filings in late 2027.

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Healthcare industry needs to get a grip on AI governance in 2025, ECRI warns

Fierce Healthcare

Risks with AI-enabled health technologies topped the list of the ECRI Institute's annual ranking of health technology hazards. | A well-known safety group debuted its annual report that lays out the top 10 health technology risks for the upcoming year. The risks of AI perpetuating bias or hallucinating answers to medical questions tops the list of risks for 2025.

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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Can you drink while taking metoprolol?

The Checkup by Singlecare

Mixing alcohol with metoprolol can come with various side effects, some of which can be serious. Many people take metoprolol, either as metoprolol tartrate or metoprolol succinate , to help manage high blood pressure and heart conditions. If youre considering drinking alcohol while taking this prescription drug, you should know the possible risks. For some people who know how they react to the medication and alcohol, drinking in moderation may be doable.

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Younger, Middle-Aged Adults Face Higher Burden of Neurologic Long COVID Symptoms

Drug Topics

The higher burden of neurological symptoms among younger and middle-aged adults translated to worse subjective quality of life, according to a recent study.

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Reimagining Established Drugs Medicines Could Lead to Potential New Applications

Pharmacy Times

The potential treatments include ivermectin, methylene blue, glucagon-like peptide-1 receptor agonists, and low-dose naltrexone.

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STAT+: AI versus AI: The emerging arms race over health insurance denials

STAT

Like many Americans, Holden Karau said she was fed up with health insurance. The software engineer’s disillusionment began in 2019, when her insurer, UnitedHealthcare, balked at covering physical therapy after she was hit by a car and could not walk. She said the hassles piled on stress, forced her to pay more out of pocket, and delayed access to care she needed to recover from multiple broken bones.

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Primary care market will see major shifts by 2030 as payers, nontraditional providers gain ground

Fierce Healthcare

Two years ago, Bain and Company forecasted ma | Nontraditional providers will account for about one-third of the primary care market in 2030, according to Bain and Company. Payer-owned primary care, population-focused models and advanced primary care providers are all poised for growth.

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