November, 2024

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IVIG Demonstrates Effectiveness in Several Neuroimmune Conditions, Indicating Potential for Long COVID Treatment

Pharmacy Times

Intravenous immunoglobulin (IVIG) has proven efficacy in autoimmune neuropathies, with mixed but promising outcomes in severe COVID-19 cases and post-acute sequelae of SARS-CoV-2 infection trials.

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Opinion: Pediatrics is becoming medicine’s largest skeleton crew

STAT

Two years ago, the RSV epidemic shook pediatric hospitals across the country along with the pediatric residents in them. One of us, Faith, was a resident at the time, and she and her colleagues refer to it as the dark ages : Whether they were arriving for their morning shifts or leaving their night shifts, the number of patients they took care of would not change for weeks at a time.

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Smart ring maker Oura picks up $75M series D, inks strategic partnership with Dexcom

Fierce Healthcare

Oura is partnering with medical device maker Dexcom to integrate data from glucose biosensors with the Oura Ring, which tracks sleep, heart rate and activity. | Oura is partnering with medical device maker Dexcom to integrate data from glucose biosensors with the Oura Ring.

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PTC wins FDA approval for first brain-delivered gene therapy Kebilidi

Fierce Pharma

The FDA issued its first stamp of approval for a cell or gene therapy back in 2017 to Novartis' Kymriah. | The gene therapy has already been approved to treat AADC deficiency in Europe and the U.K., among other countries, where it's branded as Upstaza.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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The evolving role of AI in drug submission and approval: An expert perspective

pharmaphorum

Discover an expert perspective on how artificial intelligence is transforming the drug submission and approval process in the pharmaceutical industry. Explore the evolving role of AI in drug development.

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Digital transformation expected to shorten drug development timelines

Pharmaceutical Technology

Pharmaceutical professionals expect digital solutions to solve drug development headaches, with AI already proving disruptive.

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More Trending

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STAT+: UnitedHealth pays its own physician groups considerably more than others, driving up consumer costs and its profits

STAT

UnitedHealth Group is paying many of its own physician practices significantly more than it pays other doctor groups in the same markets for similar services, undermining competition and driving up costs for consumers and businesses, a STAT investigation reveals.   The findings, drawn from a sample of practices across the country, expose the effects of a deepening conflict of interest: Rather than use its size and market power to drive down the cost of care, UnitedHealth, as the corpor

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Primary care player Forward shutters after raising $400M, rolling out CarePods

Fierce Healthcare

Primary care player Forward is abruptly shutting down its operations, closing its locations and canceling scheduled visits, the company publicly announced Wednesday. | Primary care player Forward is abruptly shutting down its operations, closing its locations and canceling scheduled visits, the company publicly announced Wednesday.

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BMS, Merck, Amgen and more must look to M&A to offset looming patent lapses: Leerink

Fierce Pharma

As a wave of patent expirations encroaches upon many of the world’s top drugmakers, companies will need to be diligent in acquiring external products with the potential to launch in the near term. | As a wave of patent expirations encroaches upon many of the world’s top drugmakers, companies will need to be diligent in acquiring external products with the potential to launch in the near term, according to a new loss of exclusivity report from Leerink Partners.

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AZ confirms China president has been detained

pharmaphorum

AstraZeneca has revealed that its top executive in China, Leon Wang, has been detained by Chinese authorities

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Spravato is just the beginning in a new wave of depression meds

PharmaVoice

Psychiatry is getting more targeted as drugmakers develop a new range of treatments for depression.

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Analysis Finds Low-Income Countries Face More Cancer-Related Deaths and Inequities in Therapy Access

Pharmacy Times

Potential solutions can include international funding, improved primary health care measures, and cost-effective screening methods.

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California health officials: Bird flu virus found in raw milk for sale

STAT

Health officials in California have discovered bird flu virus in raw milk for sale in a store in the state, a development scientists following the ongoing outbreak of bird flu in dairy cows have been anticipating and worrying about for some time. While the human health implications of drinking H5N1-laced milk are unknown, scientists who study the virus have been fearful of what consuming milk containing the virus could do.

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Amazon One Medical rolls out telehealth treatment services in competition with Ro, Hims & Hers

Fierce Healthcare

Amazon One Medical is rolling out a new service to provide Prime members access to clinical treatments for common health and lifestyle conditions like men's hair loss and anti-aging skin care. | Amazon One Medical is rolling out a new service to provide Prime members access to clinical treatments for common health and lifestyle conditions like men's hair loss and anti-aging skin care.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Daiichi Sankyo links up with Korea's Alteogen on subcutaneous Enhertu in $300M licensing deal

Fierce Pharma

A subcutaneous version of Daiichi Sankyo’s AstraZeneca-partnered blockbuster antibody-drug conjugate (ADC) Enhertu could be in the works from Korea’s Alteogen following a licensing deal worth up to | Alteogen will use its human hyaluronidase hybridization platform to develop a subcutaneous formulation of the blockbuster antibody-drug conjugate.

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AI tool spots long COVID in electronic health records

pharmaphorum

Mass General Brigham researchers have developed an AI that can spot hidden cases of long COVID from electronic health records

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GSK CEO addresses declining trust in vaccines following Trump re-election

Pharmaceutical Technology

GSK CEO Emma Walmsley said the sector would need to wait to see who is appointed in key roles in the Trump administration to gauge impact.

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FDA Grants Rare Pediatric Disease Designation for Treatment of Neonatal SP-B Deficiency

Pharmacy Times

The disorder presents as severe lung disease, with lung transplantation as the only current therapeutic option for long-term survival.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Cassava Sciences and its Alzheimer’s drug are done. The damage lingers

STAT

Four years on, the Cassava Sciences story ended Monday exactly as many knew it would — with the company’s experimental drug for Alzheimer’s disease, simufilam, proving to be nothing more than a placebo in a large clinical trial.  The negative outcome is devastating for the nearly 2,000 participants in this study and a second study also shut down Monday.

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Providers, payers focused on initial 'quick wins' for AI with plans to grow investment: survey

Fierce Healthcare

More than half of health system and health plan executives say AI is an immediate priority, and 73% are increasing their investments in the technology, a new C-suite survey finds. | More than half of health system and health plan executives say AI is an immediate priority, and 73% are increasing their investments in the technology, a new C-suite survey finds.

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AstraZeneca to go on defense for Andexxa as FDA questions bleeding reversal agent's safety ahead of adcomm

Fierce Pharma

As a council of outside experts prepares to meet Thursday to discuss AstraZeneca’s Andexxa, the FDA has flagged “major safety findings” linked to the British drugmaker’s bleeding reversal agent.

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Why whooping cough cases are spiking across the U.S.

STAT

Whooping cough cases are up sixfold from the same time last year in the U.S., affecting states ranging from Pennsylvania and New York on the East Coast to Wisconsin and Ohio in the Midwest and California and Washington out west. Experts say the spike in cases is likely a return to the pre-pandemic cycle , in which cases of the illness would ebb and flow about every five years.

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STAT+: BridgeBio wins FDA approval for heart disease drug

STAT

The Food and Drug Administration approved on Friday a new medicine from BridgeBio for patients with a progressive heart disease — the first new treatment for the condition in over five years and the company’s first significant commercial product. The drug, known scientifically as acoramidis, will be sold by BridgeBio under the brand name Attruby.

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Opinion: Why cancer advocates like me are leaving X

STAT

A version of this essay first appeared on Janet Freeman-Daily’s blog, Gray Connections. I’ve been living with and communicating about lung cancer for over 13 years. Since 2011, the year I was diagnosed, I’ve been active in one or more online lung cancer patient groups. Since 2012, I’ve been blogging and on social media, connecting with the lung cancer community and learning/sharing developments in cancer research.

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STAT+: RFK Jr. is exploring a plan to upend Medicare’s physician payments system

STAT

WASHINGTON  — People close to Robert F. Kennedy Jr. are exploring a proposal that could upend how physician payment is determined in America, four sources familiar with the process told STAT.

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Vanessa Kerry is on a mission to make the health care system resilient to climate change

STAT

Vanessa Kerry, a pulmonary and critical care physician, founded Seed Global Health more than a decade ago to tackle inequities in health care systems around the world, especially in countries with fewer resources. Climate change is exacerbating these disparities, she told STAT in an interview, as is our inability to address the crisis with the urgency it demands.

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What YouTube Health is doing to combat misinformation and promote evidence-based content

STAT

YouTube plays a unique role in people’s everyday lives, says Garth Graham, the company’s global head of healthcare and public health. “People come to us to learn how to fix their fridge and to learn about medicines,” he said in an interview. “There’s a lot of responsibility, and we take that seriously. Responsibility is at the core of how YouTube works and how we treat sensitive information, particularly around health.

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STAT+: Recursion, the AI drug development company, cuts more jobs after finalizing Exscientia merger

STAT

Recursion Pharmaceuticals, one of the most advanced companies using artificial intelligence and machine learning tools to expedite drug development , laid off employees after closing a merger last week.

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Opinion: The FDA’s risky action on compounding weight loss drugs

STAT

When Makena, a drug designed to prevent preterm births, hit the market in 2011 at $1,500 per dose, it drew rife backlash. The drug was based on an active ingredient that had been available for many years at a much lower cost. Confronted with the public outcry, the FDA took an unusual step: It allowed pharmacies to continue making their own copies of the drug through the practice of pharmacy compounding, selling it at a fraction of Makena’s price.

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H5N1 bird flu virus in Canadian teenager displays mutations demonstrating virus’ risk

STAT

The genetic sequence of the H5N1 bird flu virus that infected a teenager in British Columbia shows that the virus had undergone mutational changes that would make it easier for that version of H5N1 to infect people, scientists who have studied the data say.  There’s currently no evidence the teenager, who remains in critical condition in hospital, infected anyone else.

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Opinion: RFK Jr. says he isn’t an anti-vaxxer. He’s wrong

STAT

If he can make it past the Senate, Robert F. Kennedy Jr. will be the next secretary of Health and Human Services. Since the position was created, each secretary has had significant experience in public health, health care administration, or related government work. None has listed “spreading vaccine misinformation” as their primary health care experience.

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STAT+: Amgen drug leads to substantial weight loss in study, but questions remain about competitiveness

STAT

New data from a mid-stage study of an Amgen obesity drug showed that it helped participants lose a substantial amount of weight, but questions about how competitive it could be appear to be shaping the response to the news, with the company’s share price falling on the announcement.  Amgen said Tuesday that that its drug, MariTide , led to an average of roughly 20% weight loss over a year in the Phase 2 study in participants who had obesity or who were overweight without type 2 diabe

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STAT+: New report urges guidelines — and some restrictions — on stem cell-based embryo models

STAT

LONDON — Policymakers and scientific groups need to specify guidelines for the burgeoning field that uses stem cells to mimic aspects of embryonic development, including by establishing certain red lines on research, an influential U.K. bioethics group said Wednesday in a new report.  Specifically, the report from the Nuffield Council on Bioethics says that researchers should not use these stem cell-based embryo models to try to start a pregnancy in a person or animal, and should not

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