July, 2024

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The Girls Are Back: One Pharmacist’s Journey to Save His Community Pharmacy

Drug Topics

Mayank Amin, PharmD, RPh, MBA, sat down with Drug Topics on part 1 of an episode of Over the Counter to share his experiences transforming a shuttered independent pharmacy into a thriving community hub.

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FTC Intends to Sue Biggest Pharmacy Benefit Managers for Unfair Negotiating Tactics

Pharmacy Times

In a follow-up to the interim FTC report documenting the business practices of PBMs and the power they hold in the pharmaceutical industry, the Commission now seeks to sue the 3 largest PBMs in the country for driving up the price of insulin and other essential drugs.

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STAT+: Sarepta demanded Duchenne patient advocacy group censor video critical of the company

STAT

Sarepta Therapeutics demanded a prominent patient advocacy organization censor a video that contained pointed criticism of the company’s recently approved gene therapy for Duchenne muscular dystrophy, STAT has learned. The incident raises questions about the financial ties between Sarepta and the advocacy group, Parent Project Muscular Dystrophy, and whether the drugmaker uses its money to influence, or even muzzle, debate over its Duchenne medicines.

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Humana inks multi-year partnership with Google to invest deeper in cloud, gen AI technologies

Fierce Healthcare

Humana inked a new multi-year agreement with Google Cloud to modernize its cloud infrastructure and build out generative AI solutions. | Humana inked a new multi-year agreement with Google Cloud to modernize its cloud infrastructure and build out generative AI solutions.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Amgen, BMS and Merck have the most exposure as Big Pharma eyes $183B patent cliff: analyst

Fierce Pharma

While patent cliffs are looming for many of biopharma’s top-selling products, the industry has enormous capacity to respond as “conditions for M&A are favorable,” according to a research note f | While patent cliffs loom for many of biopharma’s top-selling products, the industry has enormous capacity to respond as “conditions for M&A are favorable,” according to a July 11 research note from Morgan Stanley.

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EMA Accepts GSK Application for Blenrep Combinations in Multiple Myeloma Treatment

BioPharm

GSK’s submission is supported by Phase III trials showing significant progression-free survival benefit and positive overall survival trends using Blenrep combinations compared to standard care.

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FTC Report Acknowledges Impact Pharmacy Benefit Managers Have on Cost, Accessibility of Prescription Drugs

Pharmacy Times

In a new report, the FTC says pharmacy benefit managers act as middlemen in the pharmaceutical industry, leading to the squeezing of independent pharmacies and increases in prices for patients.

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STAT+: How UnitedHealth harnesses its physician empire to squeeze profits out of patients

STAT

UnitedHealth Group started out as a small, Minnesota health insurance company and has since morphed into a modern-day Standard Oil, exerting unmatched dominance over health care in the United States. It’s no secret that UnitedHealth is a colossus: It’s the country’s largest health insurer and the fourth-largest company of any type by revenue, just behind Apple.

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Optum lays off more employees at Landmark, OptumInsight

Fierce Healthcare

The sprawling enterprise that is UnitedHealth Group is undergoing more layoffs under its Optum umbrella. | UnitedHealth's Optum is again laying off workers, with the scope unconfirmed. Landmark Health is downsizing once again and leaving major metropolitan areas.

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Game on: Lilly's Alzheimer's drug Kisunla, a challenger to Biogen and Eisai's Leqembi, gains full FDA nod

Fierce Pharma

After turning down Eli Lilly’s Alzheimer’s disease drug donanemab for an accelerated approval last year, the agency has now offered the anti-amyloid therapy—and a competitor to Eisai and Bioge | After turning down Eli Lilly’s Alzheimer’s disease drug donanemab for an accelerated approval last year, the agency has now offered the anti-amyloid therapy, a competitor to Eisai and Biogen’s Leqembi, a full approval.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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How NVIDIA grew with the healthcare market instead of pushing into it

Pharmaceutical Technology

As the use of AI soared across healthcare, NVIDIA fit the bill in providing the necessary technology – and its stock tells the same story.

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PBM Reform Law Aims to Support Local Pharmacies in Pennsylvania

Drug Topics

House Bill (HB) 1993 seeks to increase PBM transparency and accountability in an effort to combat the rising cost of prescription drugs.

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Notable Comorbidities and Unmet Needs in Pediatric Asthma

Pharmacy Times

The authors emphasize that clinical research should focus on real-world difficulties, and pediatric asthma control should be seen as a health care priority.

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Vaccination slashes risk of long Covid, says large study tracing cases through Delta and Omicron variants

STAT

Vaccination lowers the chance of developing long Covid, according to a large new study that also found that the risk of serious complications has diminished but not disappeared as new coronavirus variants emerged. The study, published Wednesday in the New England Journal of Medicine , compared the health records of more than 440,000 Veterans Affairs patients who were infected with Covid-19 with records of more than 4 million uninfected people.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Global IT outage takes down health system EHRs, forces hospitals to cancel non-emergency services

Fierce Healthcare

A widespread outage to Microsoft systems has impacted health systems, hospitals and clinics as electronic health record software has been knocked offline, forcing providers to cancel non-emergency | A widespread outage to Microsoft systems has impacted health systems, hospitals and clinics as electronic health record software has been knocked offline, forcing providers to cancel non-emergency procedures and services.

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Senate unanimously endorses legislation targeting pharma 'patent thickets'

Fierce Pharma

Even as pharma companies have yet to feel the full effects of the Inflation Reduction Act, Senate lawmakers have turned their attention to another facet of drug pricing with a bill meant to cr | The bill looks to limit the number of patents that companies can assert in litigation on individual products. It's intended to crack down on "patent thickets," which can delay and thwart generic competition.

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Bill that would cut down ‘patent thickets’ clears Senate

pharmaphorum

The US Senate has come together to pass a bill that aims to prevent pharma companies from filing multiple patents around biologic drugs as a way to delay biosimilar competitors.Lawmakers unanimously passed the Affordable Prescriptions for Patients Act of 2023 (S-150), which is part of a lengthening list of measures being taken by Congress to curb the prices of medicines in the US.

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Eco HPLC-based method shows promise for Z-alkene synthesis

European Pharmaceutical Review

Japanese researchers have developed a new method for photoisomerisation of E -cinnamamides to Z -cinnamamides. The approach uses a recycling photoreactor coupled with a high-performance liquid chromatography (HPLC) system. As organic compounds, many Z -alkenes “cannot be prepared through conventional methods involving thermodynamic methods”. On the other hand, “photoisomerisation can offer good yields”, they noted.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Research Results Show Promise Toward Development of a Universal Influenza Vaccine

Pharmacy Times

Despite the century-long period of virus evolution, 6 of the 11 primates that received a cytomegalovirus-expressed flu vaccine survived the exposure to H5N1 flu.

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At an Iowa county fair, a tradition carries on despite bird flu anxiety in the dairy barn

STAT

DECORAH, Iowa — It was livestock check-in day at the Winneshiek County Fair, and the dairy barn was consumed with a kind of pre-prom anxiety. A cow named Daiquiri was lumbering back from the milking parlor, adjusting to a new schedule that would have her “mammary system” bulging for showtime. Kennedy was getting a fresh shave, tufts of udder-fuzz drifting to the floor, revealing her resplendent venation.

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Humana posts $679M in Q2 profit as it faces continued Medicare Advantage headwinds

Fierce Healthcare

Humana affirmed its guidance for the year as it continues to face headwinds in the Medicare Advantage (MA) space. | Humana affirmed its guidance for the year as it continues to face headwinds in the Medicare Advantage space.

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FDA proposes cell and gene therapy site tours to help regulators learn from industry

Fierce Pharma

It's no secret that cell and gene therapies have faced manufacturing hurdles as the advanced medicines have become increasingly popular in recent years. | It's no secret that cell and gene therapies have faced manufacturing hurdles as the advanced medicines have become increasingly popular in recent years. Now, the FDA is proposing to work directly with industry through a series of facility tours that could enable both sides to learn something from each other.

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Changing Faces: Digital and supplier hires from April 2024

pharmaphorum

Changing Faces explores the digital and supplier hires from April 2024, with a focus on companies like SPT Labtech, Sphere Fluidics, Newel Health, and Diaceutics. Stay updated on the latest developments in the industry.

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‘Accidental’ media switch leads to CAR T therapy discovery

European Pharmaceutical Review

Altering the conditions that T cells are grown in can improve CAR T-cell therapy, US researchers have found. Discovered by chance, their new method has potential to treat solid cancer tumours more efficiently, according to the findings. Putting T cells on a keto diet [putting our T cells on a three-day ‘keto’ diet] showed reduced maturity at the end of the manufacturing process.

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Twice-Yearly Lenacapavir Effective in Significantly Reducing HIV Infections in Cisgender Women

Pharmacy Times

Adherence and efficacy were both higher in patients with HIV who took twice-yearly lenacapavir compared to those on oral preexposure prophylaxis medication.

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Opinion: Functional neurological disorder is not an appropriate diagnosis for people with long Covid

STAT

Long Covid — the name adopted for cases of prolonged symptoms after an acute bout of Covid-19 — is an umbrella diagnosis covering a broad range of clinical presentations and abnormal biological processes. Researchers haven’t yet identified a single or defining cause for some of the most debilitating symptoms associated with long Covid, which parallel those routinely seen in other post-acute infection syndromes.

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Digital health funding hit $5.7B through June, on track to surpass 2019 and 2023, Rock Health reports

Fierce Healthcare

U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year. | U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year.

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Lilly's Mounjao triggers more weight loss than Novo Nordisk's Ozempic: study

Fierce Pharma

Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? | Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? While a head-to-head trial pitting the two treatments remains ongoing, new evidence shows that Lilly’s tirzepatide may be the superior weight loss product.

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ASCO 2024 - Matteo Levisetti

pharmaphorum

Stay updated on Matteo Levisetti, the chief medical officer at CUE Biopharma, post ASCO 2024. Learn about his latest research and contributions in the field of biopharma.

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UK’s antibiotic subscription funding model – a route to market sustainability?

Pharmaceutical Technology

On 8 May, the UK was the world's first government to formally implement a new model for the funding and support of novel antibiotic commercialisation.

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DEA Proposed Rule Seeks to Reclassify Marijuana

Pharmacy Times

Pharmacists could play a major role in answering patient questions and providing counseling about cannabis

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Opinion: Why aren’t philanthropists stepping up to support nursing education?

STAT

Michael Bloomberg’s donation of $1 billion to Johns Hopkins University to support medical education goes beyond similar gifts to other medical schools. The Bloomberg gift provides support to students in Hopkins’ schools of nursing and public health, not just in its medical school. As health professionals and educators, we are thrilled to see philanthropists supporting the future of medical training in the U.S.

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Nearly half of beneficiaries don't know the difference between Medicare and MA: survey

Fierce Healthcare

The U.S. healthcare system remains complex and inaccessible, leaving many seniors feeling uninformed, according to a new survey from digital health company DUOS. | Seniors are growing more comfortable with technology, but many still don't understand key differences between major health programs.

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