June, 2021

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BioNTech takes its first cancer vaccine into phase 2

pharmaphorum

It would be easy to forget that back in 2019, BioNTech was an early-stage biotech firmly focused on cancer vaccines, before being catapulted onto the world-stage with its COVID-19 shot. Now, the German company has issued a reminder of its original R&D mission with the start of the first phase 2 trial of BNT111 – the first of several cancer vaccine candidates – in patients with skin cancer.

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Phesi COVID-19 study indicates obesity a major complicating factor

Outsourcing Pharma

The virtual clinical development firmâs analysis of patient profiles reflects obesity is the most significant indicator for severity in those under 40.

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The Rise of Audio Social Networks – Where Pharma Can Make an Impact

Pharma Marketing Network

Anyone with a smart device has been feeling the grueling effects of social isolation and screen fatigue since the start of the COVID-19 outbreak. Recently, we have witnessed a flood of new “audio-social apps” and audio features on social media platforms, aiming to finds new ways to connect, curb loneliness and cut excessive screen exposure. What are some of these audio-focused platforms and where can pharma play a role?

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NHS England announces extra funding for young people’s mental health services

Pharma Times

An extra £40m will go toward enhancing mental health services for children and young people

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Feeling Hot Hot Hot

Dr. Jamie Hardy: The Lifestyle Pharmacist

Heat stroke and heat exhaustion are serious, life-threatening conditions. More than 600 people in the United States are killed by the extreme heat every year, according to the Centers for Disease Control and Prevention. How to protect yourself from heat exhaustion and heat stroke. Protecting yourself from the dangers of heat exhaustion and heat stroke is a must.

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Top 10 Career Options for Pharmacy Graduates

Pharma Mirror

There are widespread misunderstandings about pharmacists’ job that make many prospective students give up on their dreams. But we are here to bring some light about what pharmacists do and don’t do. If you ask 10 different people “What do pharmacists do?”, they will all reply “They sell medications in drug stores”. But if you ask us, we have a far cry from that answer.

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Novartis, Molecular Partners launch trial to test ensovibep as COVID treatment

Outsourcing Pharma

The EMPHATHY clinical trial will enroll patients with COVID-19 to test the drugâs effectiveness in preventing worsening of symptoms and hospitalization.

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Dynamic Global Events 2021

Pharma Marketing Network

Dynamic Global Events (“DGE”) is the Life Science Leader in providing B2B Events. Our name is derived from our Goal – to serve the dynamic informational and networking needs of the Pharmaceutical, Biotechnology, Healthcare, Medical Device and allied industries. DGE Virtual, Hybrid and Live Events: Engage Audiences. Facilitate Information Exchange. Accelerate Partnerships.

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AZ, Pfizer/BioNTech vaccines ‘highly effective’ against Delta variant

Pharma Times

New real world data from PHE shows vaccines can protect against hospitalisation caused by variant

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Shared decision making recommendations will ensure people are at the heart of healthcare

NICE

Six years ago, after major surgery, I was diagnosed with Leiomyosarcoma, a soft tissue cancer. In the months - years even - leading up to that diagnosis, I experienced the exact opposite of shared decision making. Decisions were taken for me, not with me. There was no full discussion of the various options available, nor explanation of their likely consequences.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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What is Registration Drift in pharmaceutical manufacturing, and how can I avoid it?

Pharma Mirror

By Dr Ash Ramzan, founder and principal consultant, Woodley BioReg During a pharmaceutical product’s lifetime, it’s widely known and accepted that manufacturing processes will drift within their specified ranges — typically due to equipment wear-and-tear and operator variance. To maintain the ‘validated state’, diligent producers spend a lot of time and effort in ensuring validation and periodic re-validation of processes to ensure that any process drift is accounted for and controlled.

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Digital fabric could be used to measure health data

pharmaphorum

Researchers in the US have developed a wearable fabric that can sense, store and analyse data that could be used to measure physiological functions or detect illness. The team from Massachusetts Institute of Technology (MIT) claim this is the first example of a fabric which can record data in a digital rather than in an analogue format, allowing it to be programmed like any other digital device.

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Michael J. Fox Foundation shares Parkinson’s genetic data

Outsourcing Pharma

In partnership with 23andMe, the group has released a wealth of new de-identified data from the largest-ever Parkinsonâs cohort, to aid future research.

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Planning With Intention: Lessons in Authentic Communication From SXSW 2021

Pharma Marketing Network

After a year of tech-mediated communication, it’s hard to get excited about another screen interaction. Most of us want to connect in person … to have authentic interactions. Of course, tech can’t take the place of in-person – but a mindful approach to tech can make communication more meaningful. Whether it’s planning season or not, it’s worth considering how this insight can inform how brands communicate with patients and healthcare providers (HCPs).

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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BioMarin resubmits haemophilia A gene therapy to the EMA

Pharma Times

Company initially withdrew a marketing authorisation application for the gene therapy last year

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Headache Location Meaning and Treatment

BuzzRx

A headache is a very common problem. Most people have experienced one at some point in their lives. In fact, according to the International Headache Society, National Headache Foundation, and World Health Organization, 75% of people have had a headache within the past year. But not all headaches are the same. A headache can cause throbbing or dull pain, constant pain or pain that comes and goes, and pain all over the head or only on one side.

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Vectura Signs Pre-Clinical Development Agreement with Incannex to Advance IHL-216A for the Treatment of Traumatic Brain Injury

Pharma Mirror

Vectura Group plc, an industry leading inhalation CDMO, today announced it has signed an agreement with Incannex Healthcare Limited, an Australian cannabinoid medicines development company, to provide pre-clinical development services for IHL-216A, Incannex’s proprietary inhaled drug product for the treatment of traumatic brain injury (TBI). Under the terms of the agreement, Vectura will undertake formulation screening studies, manufacturing process optimisation studies and stability assessments

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Novo Nordisk crowns cell therapy pipeline with $598m Heartseed deal

pharmaphorum

Novo Nordisk is paying $55 million upfront to secure rights to a cell therapy for heart failure developed by Japanese startup Heartseed. The Danish drugmaker has acquired exclusive rights outside Japan to Heartseed’s HS-001 therapy based on heart muscle cells (cardiomyocytes) derived from human stem cells, and is due to start the phase 1/2 LAPiS trial in Japan later this year.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Partnership delivers research, care to diverse communities

Outsourcing Pharma

Elligo Health Research is joining forces with Laguna Clinical research Associates to expand access to clinical care to a broader range of patient populations.

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Richard Schwartz

Pharma Marketing Network

Richard has been focused on optimizing healthcare experiences for patients, clinicians, and the people surrounding and supporting them. He has worked within life sciences organizations, leading publishers, consultancies, agencies, digital health, and technology solutions support our journeys through illness and to wellness. He has served as an advisor to TEDMED, DreamIT Ventures, Thomas Jefferson University’s Health Design Lab, the NYC Media Lab, and NYC’s Combine Accelerator.

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Researchers identify new drug class with potential in BRCA-mutated tumours

Pharma Times

POLQ inhibitors could be used to kill PARP inhibitor-resistant cancer cells

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Medication Adherence and the Importance of Packaging

Lifewell Rx Pharmacy

According to a study published in the National Library of Medicine, medication non-adherence may lead to “worsening condition, increased comorbid diseases, increased health care costs, and death.” To prevent this, patients must work with a pharmacy to store prescriptions correctly. For example, packaging plays a vital role in promoting medication adherence.

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Alfa Laval makes ‘full-single-use’ cell harvesting possible amid industry challenges

Pharma Mirror

As growing strain on pharmaceutical technology necessitates more efficient practice, Alfa Laval has launched the CultureOne™, the industry’s first premium separator system for single-use cell culture processing. According to Bioplan Associates, single-use bioprocessing technologies now dominate the pre-commercial manufacturing space. However, Alfa Laval states many companies have not been able to make the transition to ‘full-single-use’ when harvesting proteins due to the lack of a single-use di

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Ensuring accessibility: Crossing the digital divide in healthcare

pharmaphorum

“Rarely does the answer come from the boardroom” – what can user experience teach us about building accessible digital health? No one should be left behind as the world embraces digital healthcare say leading user experience voices. The experts discussed the benefits and merits of co-creation during a session on bridging the digital divide, held during the recent Patient Experience Digital Summit.

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FDA approves Biogen’s Alzheimer's drug, Aduhelm

Outsourcing Pharma

The US Food and Drug Administration (FDA) has approved Biogenâs Aduhelm (aducanumab) for the treatment of Alzheimerâs: making it the first new treatment approved for the disease since 2003.

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Gender Pay Gap Worsens Within European Life Sciences Industry

Pharma Marketing Network

The Healthcare Businesswoman’s Association Europe region released an update to its 2018 industry gender pay gap report that shows there is a clear increase in the pay gap between men and women in the life sciences sector in Europe. The median pay gap increased from 11 percent to 13 percent however there is better news looking at individual countries and industry sectors.

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Janssen’s myeloma CAR T therapy cilta-cel demonstrates ‘sustained efficacy’

Pharma Times

Updated study results showed an overall response rate of 98% with a longer-term follow-up at a median of 18 months

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Venlafaxine & Weight Gain? Can you gain weight?

Druggist

Venlafaxine & weight gain? The focus of this post is to explore evidence be one of the most common side effects of venlafaxine. Additionally, I will talk about other aspects of venlafaxine, including licensed use, and common side effects. What is Venlafaxine? Venlafaxine is an antidepressant drug used to treat major depression, general and social anxiety disorders and panic conditions (BNF, 2021).

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“Ethno-pharma” Opportunities in India

Pharma Mirror

In the new normal scenario of Healthcare, where the approaches are patient-centric and no longer product-centric, traditional and integrative medicinal practices are rooting to the greater extent so does the ‘Ethno-pharmacy’ At the intersection of social and natural sciences, Ethno-pharmacy is a field that focuses on the traditional medicines (and pharmaceuticals) and the cultural determinants to investigate the possible use/perception of traditional medicines (and also pharmaceutica

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Artificial pancreas will be piloted in 1,000 diabetics, says NHS CEO

pharmaphorum

NHS England will provide artificial pancreas devices to 1,000 type 1 diabetes patients as part of a pilot study of the technology, according to chief executive Sir Simon Stevens. The diabetics will be offered the closed-loop systems, which continually monitor glucose levels in the blood and uses the data to automatically adjust the dose of insulin delivered by an externally worn pump, at around 25 specialist centres across England.

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Australia, NZ appealing to clinical researchers: Greenphire

Outsourcing Pharma

Thanks in part to swift COVID-19 response and relatively low infection rates, more sites and sponsors are looking at the region to locate their studies.

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Robin Kamen

Pharma Marketing Network

Robin Kamen is an experienced innovator in digital strategy with a deep background in leadership positions for healthcare and consumer products companies. She has worked with many omnichannel brands to use digital marketing technologies to improve B2C and B2B customer engagement funnels and drive sales and retention. She is also skilled in developing the change management often needed to secure buy-in for and to successfully operate digital strategies.

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US approves Pradaxa as oral blood thinning med for children

Pharma Times

First oral blood thinning drug approved for paediatric patients in the US

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