Fri.Dec 13, 2024

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Patients Before Monopolies Act to End Conflicts of Interest Between Pharmacies, PBMs

Drug Topics

US Senators introduced the bipartisan bill addressing pharmacy benefit managers and their affiliated pharmacies.

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Will the ‘anti-woke’ movement derail DEI efforts in pharma?

PharmaVoice

Amid the DEI backlash in corporate America, pharma leaders are quietly adjusting tactics.

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In This Issue: Total Pharmacy December 2024

Drug Topics

See whats trending in pharmacy with a preview of the Total Pharmacy December issue.

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Five Lessons Learned About Antimicrobial Stewardship Metrics

IDStewardship

In this article an experienced antimicrobial stewardship pharmacist discusses lessons learned from navigating antimicrobial stewardship metrics. Authored by: Timothy P. Gauthier, Pharm.D., BCPS, BCIDP Article posted 13 December 2024 If you cannot measure it, you cannot determine if you have changedit. Antimicrobial stewardship metrics are essential for identifying, acting on, and re-evaluating opportunities to enhance the safe and appropriateuse of antibiotics.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Psychiatric Pharmacist Working to Optimize Treatment, Improve Patient Safety

Drug Topics

A conversation with Nina Vadiei, PharmD, BCPP, clinical associate professor in the Division of Pharmacotherapy at University of Texas at Austin College of Pharmacy and a clinical pharmacy specialist in psychiatry at the San Antonio State Hospital.

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Patients With PV Who Switched from Hydroxyurea to Ruxolitinib Had Improved Hematocrit, White Blood Cell Counts

Pharmacy Times

Improvements were observed regardless of whether patients initiated ruxolitinib in the second or third line of treatment.

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More Trending

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Deciphering the Role of CDK4/6 and PDL-1 in Breast Cancer Immunotherapy Strategies

Pharmacy Times

Combining CDK4/6 and PDL-1 inhibitors enhances treatment responses in patients with hormone receptor positive and triple-negative breast cancer.

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Promising Therapies, Treatment Strategies for HR+ Breast Cancer | ASHP Midyear

Drug Topics

A conversation with Julia L. Ziegengeist, PharmD, BCOP, clinical pharmacist coordinator of breast medical oncology for the Levine Cancer Institute at Atrium Health.

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Approximately 1 in 6 US Adults With Asthma Report Non-Adherence to Medication Due to Cost

Pharmacy Times

Despite the overall decline in medication non-adherence, adult patients with asthma are continuing to report taking less or skipping doses and refilling prescriptions later to save money.

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Q&A: Importance of Managing Comorbidities for Patients with MASLD | ASHP Midyear

Drug Topics

Kathryn Litten, PharmD, discussed the pharmacists role in helping patients manage metabolic dysfunction-associated steatotic liver disease.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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SABCS 2024: Camizestrant Shows Promise in Combination with Ribociclib for Advanced Breast Cancer

Pharmacy Times

The novel camizestrant-ribociclib combination demonstrated encouraging data in advanced, pre-treated ER+/HER2- breast cancer.

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After Moderna's pediatric RSV vaccine trial hold, expert panel says more testing is needed

Fierce Pharma

Two days after the FDA revealed that it had halted enrollment in trials of respiratory syncytial virus (RSV) vaccines that involve young children, experts from an FDA advisory panel expressed their | An FDA advisory committeeexamining the halt of a trial of two Moderna respiratory syncytial virus (RSV) vaccines because of severe lower respiratory tract infections (LRTIs)echoed frustration in knowledge gaps about the disease and said that more testing is needed.

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ASH 2024: Expert Discusses Challenges, Future Research Opportunities With Bispecific Antibodies in Multiple Myeloma

Pharmacy Times

Ira Zackon, MD, explains where future research lies regarding the implementation of bispecific antibodies in community oncology settings.

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Opinion: I have a rare form of ALS. I have to fight my insurance company every six months for a game-changing drug

STAT

When I was diagnosed at age 22 with ALS, a fatal disease without a cure, I knew I was going to have to fight for my life. I just didn’t know I would also have to fight against insurance companies denying me access to life-extending treatments. Amyotrophic lateral sclerosis, or ALS, takes your ability to walk, talk, eat, and eventually breathe.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FDA Grants Breakthrough Therapy Designation to Tobevibart With Elebsiran for Treatment of Chronic Hepatitis Delta

Pharmacy Times

The treatments are currently undergoing evaluation in the SOLSTICE trial (NCT05461170).

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HHMI’s move to diversify funding sparks debate about ‘biomedical elite’

STAT

One of the world’s largest funders of biomedical research is looking to spread the wealth around a little more evenly. The nonprofit Howard Hughes Medical Institute (HHMI) will bar institutions that already have two or more beneficiaries of its Investigator Program from applying for a round of funds to be awarded in 2027. The goal is to “broaden institutional representation by encouraging applications from scientists in geographic regions where HHMI is not currently supporting scie

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Pharma prepares for CDMO growth in 2025 as CPHI Milan reports record attendance

Pharmafile

13 December 2024 Amsterdam, the Netherlands CPHI Milan the worlds largest pharma event hosted last month in Milan saw a new record attendance of 59,000 pharma executives buoyed by returning confidence and increased dealmaking on site. The events success is widely used as a proxy for overall growth in global pharma […] The post Pharma prepares for CDMO growth in 2025 as CPHI Milan reports record attendance appeared first on Pharmafile.

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Opinion: Inclusive immigration policies protect America’s health care

STAT

When I left Syria in 2014, I had a dream of becoming a U.S.-trained physician. I quickly realized that the American dream is real and that hard work truly pays off. I completed my master’s degree in international health policy and management, along with my clinical training in both internal and vascular medicine, at highly reputable institutions.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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2-year extension of telehealth, plus hospital-at-home program boost likely as negotiations crest in Congress

Fierce Healthcare

UPDATED DEC. 16, 11 A.M. ET | Members of Congress and their staffers have been at the negotiating table for the last several days on an end-of-year healthcare package that would extend Medicare telehealth waivers for two years, among other digital health wins. The deal is likely to be finalized over the weekend.

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STAT+: South African regulator decides Vertex provides sufficient access to CF drugs, angering activists

STAT

After a lengthy investigation, South African regulators decided Vertex Pharmaceuticals has sufficiently provided access to its cystic fibrosis medications, ending a high-profile episode that placed the company on the defensive over the cost of its treatments. But the move angered patient activists who argued the arrangement is inequitable and that some patients “will continue to suffer and die.

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AIM ImmunoTech gains Netherlands patent for post-Covid fatigue therapy

Pharmaceutical Technology

AIM ImmunoTech has secured a patent from the Netherlands Patent Office for Ampligen, targeting the treatment of post-Covid fatigue.

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STAT+: Report: Tuberculosis R&D funding is up, but still short of goals and dominated by a few players

STAT

Although research and development funding for tuberculosis reached new heights last year, the total fell substantially short of goals set by the United Nations and most of the increase came from just two organizations, according to a new report. Specifically, the amount spent on basic research, new treatments, vaccines, and diagnostics was $1.2 billion, the highest level since tracking of funding began in 2005 and 20% more than what was seen in 2022.

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My 72-Hour Fast

The Honest Apothecary

Monday evening I was frustrated. Four weeks ago we had begun trying the carnivore diet. For me, it was an attempt to try something different to hopefully break out of a 6-month stall in my weight loss journey. Yes, that’s right. I began exercising and eating much better 1 year ago. Over the course of […] The post My 72-Hour Fast appeared first on The Honest Apothecary.

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STAT+: For a leukemia that keeps returning, AbbVie drug may offer chance for a deep remission

STAT

SAN DIEGO — Brian Koffman found himself in a situation a couple years ago that most chronic lymphocytic leukemia patients eventually do: relapse. The expectation in CLL is that, no matter what therapy or how many therapies patients have been on, the cancer will eventually recur if the patient lives long enough. The hope is that by that time, there will be yet another treatment to try.

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Innovative biologic prefilled syringe approved in EU

European Pharmaceutical Review

The European Medicines Agency (EMA) has approved Roche’s Vabysmo (faricimab) prefilled syringe (PFS) as the EUs first and only bispecific antibody prefilled syringe for retinal conditions causing vision loss. This authorises a novel CE-labelled needle for intravitreal injection. Vabysmo 6.0mg is indicated for treating neovascular or wet age-related macular degeneration (nAMD), diabetic macular oedema (DME) and macular oedema following retinal vein occlusion (RVO).

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ASHP Midyear: Pharmacy Compounding Requires Ensuring Quality, Safety, and Preparedness

Pharmacy Times

Daily operational tasks and quality assurance measures in pharmacy compounding ensures patient safety and maintains compliance.

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STAT+: Ionis blazed trails in genetic medicine. On the cusp of a major approval, can it also be a commercial success?

STAT

CARLSBAD, Calif. — Stroll inside Ionis Pharmaceuticals’ Southern California headquarters, past the giant hanging glass sculpture of an RNA molecule, and you can’t miss it on the back wall: In bright red, a digital countdown clock ticks off the days, hours, minutes, and seconds until a moment the biotech is betting will be transformational.

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McKinsey agrees to $650M DOJ settlement over opioid consulting relationship with Purdue Pharma

Fierce Pharma

Disgraced former OxyContin marketer Purdue Pharma is on the hook for billions after agreeing to settle cases that held the company responsible for fueling the U.S. opioid crisis. | McKinsey will pay $650 million to settle with the U.S. Department of Justice, which was investigating the companys efforts to help Purdue increase its opioid sales. In exchange, the DOJ will drop its charges.

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The conclusion(?) to the bird flu mystery and a Syrian doctor on coming to the U.S.

STAT

Happy birthday to Taylor Swift! She’s now old enough to run for president of the United States (not saying she SHOULD, just that she COULD…) And happy birthday to my feature from one year ago about a little girl named Shelby , whose one-time gene therapy miracle cure took place over a grueling year. (Don’t miss the Taylor Swift name drop in the piece itself!

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Where is AI winning in drug discovery? 4 use cases to know

Fierce Pharma

Even though AI-designed drugs arent yet a household term for FDA-approved, commercially available therapies, they are a reality in clinical development pipelines. | Even though AI-designed drugs arent yet a household term for FDA-approved, commercially available therapies, they are a reality in clinical development pipelines.

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STAT+: Up and down the ladder: The latest comings and goings

STAT

Hired someone new and exciting? Promoted a rising star? Finally solved that hard-to-fill spot? Share the news with us, and we’ll share it with others.  That’s right. Send us your changes, and we’ll find a home for them. Don’t be shy. Everyone wants to know who is coming and going. And here is our regular feature in which we highlight a different person each week.

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Using metoprolol to treat anxiety

The Checkup by Singlecare

Nearly a third of all Americans will experience an anxiety disorder at some point in their lives. When symptoms are severe, medication can help. Beta blockers are a class of drugs that works on your bodys fight-or-flight responseblocking the effects of adrenaline. If youve ever experienced anxiety symptoms like sweating palms, racing heartbeat, or difficulty breathing, it may sound like a welcome respite.

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EMA backs Merck's Welireg, Bayer's ATTR med and Gilead's liver drug from $4.3B deal

Fierce Pharma

In a flurry of decisions Friday, the European Medicines Agencys human products committee recommended 17 new drugs for approval while letting Takeda withdraw from market an inflammatory bowel disea | In a flurry of decisions Friday, the European Medicines Agencys human products committee recommended 17 new drugs for approval while letting Takeda withdraw from market an inflammatory bowel disease complication medication.

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