Fri.Nov 22, 2024

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H5N1 Bird Flu: A Slowly Looming Public Health Threat

Drug Topics

Public health and infectious disease experts offered their perspectives on the 2024 US bird flu outbreak and its potential of becoming a greater public health crisis.

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STAT+: BridgeBio wins FDA approval for heart disease drug

STAT

The Food and Drug Administration approved on Friday a new medicine from BridgeBio for patients with a progressive heart disease — the first new treatment for the condition in over five years and the company’s first significant commercial product. The drug, known scientifically as acoramidis, will be sold by BridgeBio under the brand name Attruby.

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Vaccination Conversations: Mastering Patient Q&A at the Pharmacy

Pharmacy Times

When you’re unsure about answering a patient question, err on the side of caution and refer them to a pharmacist.

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Pfizer led industrywide sales surge in Q3 after several quarters of dominance by Eli Lilly, Novo Nordisk

Fierce Pharma

After six straight quarters in which Eli Lilly or Novo Nordisk achieved the highest year-over-year revenue growth among the top companies in the biopharma industry, there was a new champion in the | After six straight quarters in which Eli Lilly or Novo Nordisk achieved the highest year-over-year revenue increases among the top companies in the biopharma industry, there was a new growth champion in the third quarter.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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FDA Grants Orphan Drug Designation to RAG-21 for Treatment of ALS

Pharmacy Times

If approved, RAG-21 can offer improved outcomes in patients with amyotrophic lateral sclerosis (ALS), particularly those with aggressive subtypes.

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As other Big Pharmas face local headwinds, Pfizer doubles down on China commitment with Zai Lab antimicrobial marketing pact

Fierce Pharma

As other Big Pharmas face local headwinds, Pfizer doubles down on China commitment with Zai Lab antimicrobial marketing pact fkansteiner Fri, 11/22/2024 - 09:04

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STAT+: Sanofi plans to change payment terms for 340B hospitals

STAT

The battle over prescription drug discounts offered to hospitals under a federal program escalated as Sanofi became the third pharmaceutical company to disclose plans to change the way it will make payments. In a letter sent to hospitals and clinics on Friday, Sanofi indicated that certain hospitals covered by the 340B Drug Discount Program would receive credits for medicines ordered at full price from a wholesaler.

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Empowering community pharmacies: The key to bridging health inequalities

pharmaphorum

Community pharmacies play a crucial role in bridging health inequalities and empowering communities. Learn how the NHS and community pharmacies work together to improve health outcomes for all.

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After FDA setbacks, Lexicon slashes commercial operations in transition back to clinical-stage outfit

Fierce Pharma

For many biopharmas, it takes years of hard work to transition from being a clinical-stage drugmaker to a commercial one. Companies rarely want to make the shift back. | The pivot comes after the FDA issued a notice that the deficiencies in the company's approval bid for type 1 diabetes med Zynquista are too great to proceed for further discussion.

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FDA experts lukewarm on AZ's anticoagulant antidote Andexxa

pharmaphorum

AstraZeneca is facing some pushback as it tries to upgrade anticoagulant antidote drug Andexaa to full approval in the US.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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No Association Between High-Dose NSAIDs, Hypertension in axSpA | ACR Convergence

Drug Topics

NSAIDS are typically the first line of treatment for axial spondyloarthritis.

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Jazz gets first FDA nod for HER2 bispecific Ziihera

pharmaphorum

Jazz Pharma has claimed FDA approval for its HER2-directed bispecific antibody Ziihera as a treatment for biliary tract cancer

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Chain Pharmacist Embracing Expanded Role in the Profession

Drug Topics

On the most recent episode of Over the Counter, James Rider, PharmD, joined Drug Topics to discuss his career journey as a chain pharmacist.

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Health Canada issues NOC to J&J’s CARVYKTI for multiple myeloma

Pharmaceutical Technology

Health Canada has issued a Notice of Compliance (NOC) for Johnson & Johnson’s (J&J) CARVYKTI for multiple myeloma treatment.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Autism advocates respond to RFK Jr.; a trip to the nipple factory; a new water pollutant (don’t panic)

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. This week, a Nature paper shared a new method that can convert Teflon — and toxic “forever chemicals,” or PFAS — to harmless charcoal (and fluoride).

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“No magic wand” for Novo Nordisk, as CagriSema pen supply rumours swirl

Pharmaceutical Technology

Novo Nordisk and Ypsomed’s 2023 deal is rumoured to include an autoinjector supply for potential Wegovy successor CagriSema.

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Disconnect Between Adolescent, Caregiver Pain and Depression Symptoms in Rheumatic Diseases | ACR Convergence

Drug Topics

PROMIS scores demonstrated the disparities between reported pain and mental health outcomes.

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Oseltamivir May Shorten Hospital Stays for Children With the Flu

Pharmacy Times

Children with obesity, asthma, and gastrointestinal disease had longer durations of stays compared with children without comorbidities.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Reproductive Health Counseling and Education Crucial for Women With Rheumatic Disease | ACR Convergence

Drug Topics

Despite an interest in services, a majority of women do not have these critical conversations with their health care providers.

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Arrowhead Pharmaceuticals Submits FDA Application for Plozasiran in Familial Chylomicronemia Syndrome

Pharmacy Times

Familial chylomicronemia syndrome (FCS) currently has no FDA-approved treatment and is associated with an increased risk of acute pancreatitis.

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Cervical Cancer Screening, HPV Vaccination Lacking In SLE | ACR Convergence

Drug Topics

Systemic lupus erythematosus is associated with a higher risk of cervical dysplasia due to the inflammatory nature of the disease.

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FDA Grants Rare Pediatric Disease, Fast Track Designations to Gildeuretinol for Stargardt Disease Treatment

Pharmacy Times

As a rare and serious pediatric disorder, Stargardt disease can cause vision complications in patients.

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Nonopioid Options to Manage Chronic Pain in Veterans | ACR Convergence

Drug Topics

Chronic pain is more prevalent—and more severe—in veterans compared with the general US population.

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As J&J tries to wrap up talc litigation in the US, the company now faces class action in UK

Fierce Pharma

While Johnson & Johnson hopes to soon resolve more than 60,000 talc lawsuits with an $8 billion bankruptcy settlement in the United States, its baby power problems are only just beginning in th | While Johnson & Johnson hopes to soon resolve more than 60,000 talc lawsuits with an $8 billion bankruptcy settlement in the United States, its baby power problems are only just beginning in the U.K.

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Will Walgreens’ store closures derail its clinical trial aims?

PharmaVoice

Despite a plan to shutter 1,200 stores, the company’s chief clinical trials officer said the pharmacy juggernaut remains committed to drug research.

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Decision to Receive Pneumococcal Vaccine Among Older Adults Is Multi-Factorial, Influenced by Multidimensional Interventions

Pharmacy Times

Commonly cited factors influencing uptake of pneumococcal vaccination included knowledge of pneumococcal disease and vaccine benefits, recommendations from health authorities, and perceived risk of infection.

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Enveda raises $130m to advance AI-driven plant based drug development

Pharmaceutical Technology

The biotech uses its AI platform to discover the therapeutic potential of plant-based molecules, advancing ten candidates with the funds.

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Implementing CDC’s Core Elements of Sepsis

Pharmacy Times

The agency outlines key elements for building effective hospital sepsis programs.

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Xsolis CMO on AI’s evolution: balancing potential responsibly

Fierce Healthcare

| Heather Bassett, CMO of Xsolis, shares insights on the company's use of AI and future plans.

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Women With Natural Menopause at a Later Age May Have an Increased Risk of Asthma

Pharmacy Times

Women aged 40 to 44 years at the time of natural menopause showed about a 30% decreased risk for asthma incidence.

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Research digest: Assessing antibiotic appropriateness in hospital settings

Hospital Pharmacy Europe

A study aimed at quantifying excess antibiotic use in an acute UK hospital found that nearly a quarter of antibiotic days of therapy (DOTs) were unnecessary. The most significant opportunity to reduce antibiotic use came in optimising the pre-72 hours antibiotic review. Other important opportunities to reduce use included avoiding inappropriate initiation of antibiotics and ensuring course lengths were appropriate for each patient.

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Final Thoughts

Pharmacy Times

The panel discussion concludes with final thoughts on the future landscape of newly diagnosed multiple myeloma.

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Chutes & Ladders — CVS Health continues leadership shakeup; Providence appoints COO

Fierce Healthcare

Welcome to this week's Chutes & Ladders, our roundup of hirings, firings and retirings throughout the industry. | Welcome to this week's Chutes & Ladders, our roundup of hirings, firings and retirings throughout the industry. Please submit the good news—or the bad—from your shop, and we will feature it here at the end of each week.

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