Wed.Oct 16, 2024

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Pharmacy Education Must Keep Pace With Changing Health Care Landscape | ACCP 2024

Drug Topics

Posters presented at ACCP 2024 revealed gaps in pharmacy students’ understanding of off-label drug applications and identified strengths and weaknesses among pharmacy graduates.

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Is it time to freak out about bird flu?

STAT

If you’re aware of the H5N1 bird flu outbreak in U.S. dairy cattle — you may have seen some headlines or read something on social media — perhaps you are wondering what the fuss is about. Yes, there have been nearly a couple dozen human cases, but all have had mild symptoms. The virus does not decimate herds in the way it does poultry flocks; most — though not all — of the infected cows come through the illness OK.

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Trending Sources

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The Heart-Brain Connection: Heart Failure, Atrial Fibrillation, Coronary Heart Disease, and Dementia

Pharmacy Times

Cardiovascular diseases have a significant impact on brain health and function.

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STAT+: Inside UnitedHealth’s strategy to pressure physicians: $10,000 bonuses and a doctor leaderboard

STAT

The emails from UnitedHealth Group managers were filled with exclamation marks and pleasantries about the weather. But the underlying message to doctors in late 2020 was persistent and urgent: Hit your targets to see more patients. We need to bring in more money. At the time, deaths from Covid-19 were surging, and no vaccine was available.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Weight-loss drug firm accused of prioritising profits after halting insulin pen production

The Guardian - Pharmaceutical Industry

Novo Nordisk’s decision will force people in developing countries to use outdated glass vials and syringes, warn campaigners The pharmaceutical company behind injectable weight-loss drugs has been accused of prioritising profits over the health of people in developing countries by halting production of its insulin pens. People living with type 1 diabetes who are reliant on the human insulin produced by Novo Nordisk, will instead be given glass vials and syringes – which they say are inconvenient

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Veteran vaccine developer says U.S. response to bird flu outbreak in cattle is ‘frustrating’

STAT

Barney Graham, who for decades helped lead U.S. vaccine development efforts , said Wednesday that the lack of cooperation among U.S. agencies is hindering the country’s response to the H5N1 bird flu outbreak among dairy cattle, echoing criticisms that have been building over the past six months.  “The USDA and the CDC and the NIH are not sharing and coordinating,” Graham said, referring to the federal agriculture department, the Centers for Disease Control and Preventio

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‘Failure to rescue’: Study suggests why women fare worse than men after cardiovascular surgery

STAT

They call it “failure to rescue,” which means a surgical patient died from complications that might have been averted if recognized and treated. New research suggests that’s why women are less likely to survive high-risk cardiovascular surgery than men. Female patients who underwent four common but serious procedures —  abdominal aortic aneurysm repair, coronary artery bypass surgery, or atrial or mitral valve replacements — later developed complications a

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Pharmacist-Led Medication Management Improves Cost in Type 2 Diabetes

Drug Topics

Pharmacist-led medication therapy management can help reduce costs associated with diabetes management.

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Their research may be transformative. They worry patients won’t be able to access it

STAT

Inspiration for a career in science can come from any number of sources. For Diane Shao , a neurogeneticist at Boston Children’s Hospital and general partner at Legacy Venture Capital, her mother motivated her to take the plunge into biotech. For Jorge Diego Martin-Rufino , a physician scientist at the Broad Institute and Boston Children’s Hospital, it was the pioneering geneticist Eric Lander, who advised him during his Ph.D.

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With Gilead coming fast, GSK bolsters case for long-acting HIV PrEP drug Apretude

Fierce Pharma

With Gilead sprinting to a likely approval next year for its long-acting pre-exposure | With GSK girding for competition from Gilead Sciences, the company has presented strong results from three real-world studies of its bi-monthly injection for HIV prevention.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Buoyed by clinical success, Onward Medical charts future of neurostimulation

STAT

Onward Medical is betting big on neurostimulation as a tool to improve the quality of life for people with paralysis, said CEO Dave Marver. Bullish after recent clinical success, Marver spoke about the Swiss company’s future plans at the 2024 STAT Summit in Boston, including a device that can better regulate an underactive bladder.

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Loncastuximab Tesirine Demonstrates Promise in Managing Hemophagocytic Lymphohistiocytosis Associated With Diffuse Large B-Cell Lymphoma

Pharmacy Times

The results indicate the potential use of loncastuximab tesirine as a treatment option for the rare hyperinflammatory condition.

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STAT+: Q&A: FDA chief on why our hearts are less healthy, how obesity drugs impress him, and what worries him

STAT

Robert Califf, a cardiologist and commissioner of the U.S. Food and Drug Administration, has been deeply involved in cardiovascular research: investigating health outcomes, health care quality, and clinical research in large, complex studies. In a recent conversation with STAT, though, he invoked his role as a grandfather, challenged in a grocery store checkout line to resist the ultra-processed foods marketed to American children and adults.

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New Migraine Guidelines Aim to Help Patients Beat the Pain

Pharmacy Times

The updated recommendations include CGRP inhibitors as a first-line treatment option for chronic and episodic migraine prevention.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Opinion: Mark Cuban has no doubt he can disrupt health care

STAT

If it weren’t for Martin Shkreli, better known as the Pharma Bro, Mark Cuban might not have gone into the drug business. That’s what he told me in this week’s episode of the “First Opinion Podcast.” He first started speaking with Alex Oshmyansky — the radiologist who would become his co-founder in Mark Cuban Cost Plus Drugs — around when Shkreli was heading to prison.

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Gepotidacin NDA Under Priority Review by FDA for Uncomplicated UTI

Drug Topics

Gepotidacin is a first-in-class oral antibiotic with a novel mechanism of action.

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STAT+: Ahead of public meeting, FDA signals flexibility in evaluating smoking cessation treatments

STAT

Food and Drug Administration leaders are signaling new flexibility in the agency’s approach to evaluating new therapies to help people stop smoking.  In a perspective paper published with the National Institutes of Health this week, the agency labeled the effort to help Americans quit smoking a top priority and said it was willing to consider broader endpoints in clinical trials of smoking cessation products.

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Pfizer sticks $1.5bn on Triana's molecular glue tech

pharmaphorum

Pfizer partners with US biotech Triana Biomedicines in a deal focusing on molecular glue degraders that could be worth $1.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Morning Rounds: How UnitedHealth pressured doctors on diagnoses

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning! My editor said that the uncertainty in my write-up below on Helen’s story (“ Is it time to freak out about bird flu? “) reminded her of this iconic moment from NBC’s “30 Rock.

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NIH study backs Bavarian Nordic mpox jab for adolescents

pharmaphorum

NIH study finds Bavarian Nordic's mpox vaccine is effective in adolescents, a particularly vulnerable group amid the ongoing outbreak

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Exelixis stock rises as key drug Cabometyx withstands patent challenge

Fierce Pharma

A federal judge in Delaware has ruled in favor of Exelixis in its Cabometyx patent fight with MSN Laboratories, effectively pushing the earliest generic entry out to 2030. | A federal judge in Delaware has ruled in favor of Exelixis in its Cabometyx patent fight with MSN Laboratories, effectively pushing the earliest generic entry out to 2030.

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Want to launch a blockbuster? An AstraZeneca exec breaks it down.

PharmaVoice

Even drugs with “blockbuster potential” often fall short of expectations. Here’s what can help a new medication pass the $1 billion mark.

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Access to genomic surveillance: Open science and public health

pharmaphorum

The pandemic served as a catalyst for a revolution in genomic surveillance for tracking pathogens. The technology proved vital in aiding understanding of the evolution of and spread of virus in real time to inform public health measures, ultimately accelerating drug and vaccine development.

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U.S. News unveils annual Medicare Advantage, Part D ratings

Fierce Healthcare

Medicare's annual enrollment period is officially underway, and, to assist beneficiaries in selecting plans, U.S. | Medicare's annual enrollment period is officially underway, and to assist beneficiaries in selecting plans, U.S. News & World Report has released its list of the best Medicare Advantage and Part D insurers.

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STAT+: Pharmalittle: We’re reading about using Lilly obesity drug to reduce sick days, Sanofi workers striking, and more

STAT

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. After all, we have made it this far, so we are determined to hang on for another couple of days. And why not? The alternatives — at least those we can identify — are not so appetizing. And what better way to make the time fly than to keep busy.

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CDMO SpectronRx homes in on completion of European plant to crank out key isotope for radiotherapies

Fierce Pharma

While radiopharmaceuticals have attracted significant interest in recent years thanks to their cancer-fighting prowess, the unique makeup of the meds has presented a host of production challenges f | SpectronRx has inked an agreement to complete its first European radiolabeling plant at the Belgian Nuclear Research Center in Mol, Belgium. The facility will initially focus on the labeling of Actinium-225-based radiopharmaceuticals.

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Revolutionizing Outpatient Oncology Care: The Seamless Integration of Artificial Intelligence

Pharmacy Times

Artificial intelligence holds immense potential to address the rising demand for oncology services and improve patient outcomes by facilitating more effective, efficient, personalized cancer care.

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A controversial approval for Novocure’s device

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning. I’ve arrived in Boston for our annual STAT summit , and I successfully guilted my colleague Adam Feuerstein into baking me a cheesecake.

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Q&A: Why Value-Based Care Can Lead to Increased Revenue in the Pharmacy

Drug Topics

David Pope, PharmD, Chief Pharmacy Officer at XiFin, discussed pharmacy benefit managers and their impact on value-based care within pharmacies.

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Scilex Holding looks to separate Scilex Pharma through potential spinout, IPO

Fierce Pharma

Scilex Pharma may soon flee the nest after its parent company Scilex Holding’s board of directors granted permission to explore routes to maximize the company’s value. | Scilex Pharma may soon flee the nest after its parent company Scilex Holding’s board of directors granted permission to explore alternative routes for the drugmaker.

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5 Questions With a Pharmacist: Stevie Veach from MercyOne Pharmacy

Drug Topics

In an installment of Drug Topics’ 5 Questions With a Pharmacist, Stevie Veach of MercyOne Pharmacy in Dubuque, Iowa, talked about her pharmacy’s offerings and how they serve her community’s patients.

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Pivmecillinam – New UTI Medication Rundown

Med Ed 101

Pivmecillinam, also known as Pivya, is an oral antibiotic that was FDA-approved in April of 2024 for use against uncomplicated urinary tract infections (UTI) in female patients.1 Pivmecillinam Literature Pivmecillinam falls in the class of penicillin antibiotics. It is a prodrug that contains pivaloyloxymethylester of the amidinopenicillanic acid which is converted to mecillinam.

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Q&A: Pharmacy’s Evolving Relationship with Value-Based Care

Drug Topics

David Pope, PharmD, Chief Pharmacy Officer at XiFin, further discussed value-based care and his company’s ongoing collaboration with pharmacies across the country.

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