Tue.Apr 08, 2025

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Environmental Factors Impact Psoriasis Severity

Drug Topics

In a comprehensive review, researchers aimed to explore seasonality, environmental factors, and the genetic and epigenetic mechanisms of patients living with psoriasis vulgaris.

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The Great RIF(T): One FDA Division’s Destruction and What it Could Mean for Generic Drugs

The FDA Law Blog

By Kurt R. Karst The FDA Reduction-in-Force (Termination)or RIF(T)announced last week has resulted in countless stories in the press and on personal LinkedIn accounts from those RIFd. As the dust begins to settle and we all assess what this means for the future of FDA and the public health, generally, this blogger wanted to call out one particular division in the Office of Generic Drugs (OGD), funded by user fees under the Generic Drug User Fee Amendments (GDUFA), that was eradicated and what t

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Atopic Dermatitis May Increase Risk of Food Allergies

Drug Topics

In a review of skin inflammations link to food allergen sensitivity, researchers explored how patients with atopic dermatitis may be more susceptible to the development of food allergies.

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Unique pain research office eliminated in HHS purge

STAT

Last week’s layoffs across the Department of Health and Human Services left a significant casualty in the vast ecosystem of government-backed science: an entire division focused on researching pain.  The reduction in force enacted last week by Health Secretary Robert F. Kennedy Jr. eliminated all but one full-time position, out of roughly a dozen, within the National Institutes of Health Office of Pain Policy and Planning, a unit devoted to coordinating pain-related research across t

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Data Remain Unclear Between Asthma Incidence, Prevalence, and COVID-19

Drug Topics

Conflicting study findings show various associations between asthma and COVID-19; further data are needed.

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STAT+: As more patients get automated test results, researchers seek ways to calm their nerves

STAT

Editor’s note: This story contains a description of self-harm. Oncologist Mark Lewis has never had much of a poker face. When he walked into his cancer patient’s visit in 2022, he was wearing a big smile: The nodules in his patient’s lungs, he saw in the radiology report, were shrinking in response to treatment. His patient, though, was already upset.

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Ipsen’s Iqirvo approved for use in NHS Scotland to treat rare liver disease

Pharmafile

The Scottish Medicines Consortium (SMC) has accepted the use of Ipsens Iqirvo (elafibranor) in NHS Scotland for the treatment of primary biliary cholangitis (PBC), a rare liver disease. This marks the first new medicine for PBC to be accepted by the medical body in nearly a decade. Iqirvo is a peroxisome proliferator activated receptor (PPAR) […] The post Ipsens Iqirvo approved for use in NHS Scotland to treat rare liver disease appeared first on Pharmafile.

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Drug Advertising Expert on FDA’s Boxed Warning Labels

Drug Topics

In part 3 of our interview with Jenny Markell, BA, she discussed drug advertising trends among Alzheimers disease drugs and how FDA suggestions are not necessarily followed.

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Greener Pharmacy Guide and Toolkit launched by RPS to support sustainability

Hospital Pharmacy Europe

A digital self-assessment tool designed to help hospital pharmacy teams take practical action to support sustainability and reduce the environmental impact of pharmacy services, pharmaceutical care and medicines, while supporting patient care, has been launched by the Royal Pharmaceutical Society (RPS). The long-awaited RPS Greener Pharmacy Guide and Toolkit provides prompts to introduce more sustainable practices to reduce emissions, improve patient care, prevent ill health, tackle medicines wa

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Cognitive Behavioral, Mindfulness Therapies Reduce Daily Dosage of Opioid Use for Chronic Back Pain

Drug Topics

There were no statistically significant differences between cognitive behavioral therapy and mindfulness-based therapy in reducing the dosage for chronic lower back pain.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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High Force Research appoints Nathalie Huther as chief commercial officer

Pharmafile

High Force Research has announced that it has appointed Nathalie Huther as its first chief commercial officer (CCO) following the companys recent management buyout (MBO). This forms an important part of its business development and market expansion strategy. Huther will lead High Forces research commercial strategy, and brings a wealth of experience in commercial leadership […] The post High Force Research appoints Nathalie Huther as chief commercial officer appeared first on Pharmafile.

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GSK to advance antibody medicines for neurodegenerative diseases

European Pharmaceutical Review

GSK has agreed to develop novel medicines for neurodegenerative diseases, as part of a global licensing agreement with ABL Bio Inc, for up to 2.075 billion. This is subject to certain milestone payments across multiple potential programmes.The licensing deal will utilise ABL Bios blood-brain barrier shuttle platform Grabody-B, to advance multiple programmes across therapeutic modalities including antibody , polynucleotide or oligonucleotides, such as siRNA and ASOs.

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ELRIG appoints Del Trezise as chair

Pharmafile

ELRIG, a non-profit volunteer-led organisation dedicated to the drug discovery community, has appointed Del Trezise as chair of the board. He succeeds Melanie Leveridge, who completed her four-year term as chair. He will lead ELRIGs mission to deliver highly accessible scientific meetings and conferences. It serves a global network of over 22,000 life sciences professionals. […] The post ELRIG appoints Del Trezise as chair appeared first on Pharmafile.

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AAN 2025: APP Care Models Can Be a Solution to Promoting Patient Access and Equity Within the Neurology Space

Pharmacy Times

Advanced practice provider (APP) care models allow for health systems to better individualize care for patients, effectively meeting their needs.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Her son’s DMD diagnosis shook her world. As a biotech CEO, it was also an epiphany for better rare disease R&D.

PharmaVoice

Five years ago, Michelle Werner received her son’s Duchenne muscular dystrophy diagnosis with fear and desperation. Now, as CEO of Alltrna, she’s finding ways to turn those feelings into a better way of treating rare diseases.

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AAN 2025: Tolebrutinib Shows Promise in Slowing Disability Progression for Secondary Progressive Multiple Sclerosis

Pharmacy Times

The HERCULES trial demonstrates tolebrutinib's potential to slow disability progression in non-relapsing secondary progressive multiple sclerosis, offering a new treatment option for patients with limited therapeutic choices.

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Ethris and Lonza to develop mRNA vaccines for respiratory conditions

Pharmaceutical Technology

Ethris has partnered Lonza for the development of room-temperature stable mRNA vaccine candidates targeting respiratory conditions.

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Study Finds ADHD Stimulants Have Minimal Effect on Cardiovascular System

Pharmacy Times

Small changes in blood pressure and pulse were shown in patients of all ages, and the authors suggested that these are monitored carefully in patients being treated for ADHD.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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EC approves extension of indication for Janssen-Cilag’s Darzalex

Pharmaceutical Technology

The European Commission (EC) has granted approval for the extension of indication for Janssen-Cilag Internationals Darzalex SC formulation.

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Nivolumab Plus Ipilimumab Receives FDA Approval for MSI-H/dMMR mCRC

Pharmacy Times

The approval was based on efficacy and safety data from a randomized, 3-arm, open-label phase 3 CHECKMATE-8HW trial.

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EU due to meet with pharma today to discuss tariffs

pharmaphorum

European Commission President Ursula von der Leyen is scheduled to meet with EU pharma leaders today about how to respond to US tariffs.

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Bortezomib Off-Week Regimen Shows Promise for Reducing Toxicity in Multiple Myeloma

Pharmacy Times

Erin Harrell, PharmD, offers insights about managing peripheral neuropathy in patients receiving bortezomib.

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Rinvoq cleared for giant cell arteritis in EU, ahead of US

pharmaphorum

AbbVie has picked up another indication for its JAK inhibitor Rinvoq in the EU, becoming the first approved oral therapy for giant cell arteritis

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Consumers are using their insurers' websites, mobile apps and other digital platforms in greater numbers, but their experiences often fall short of expectations, according to a new report.

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Are Republicans changing course on Medicare Advantage?

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning. In case you missed it yesterday, we have a winner for this year’s STAT Madness competition. From the same institution as last year — is that a dynasty I see forming?

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FDA nod broadens use of Brainomix's stroke AI

pharmaphorum

Brainomix has been granted FDA approval for a new feature for its AI-powered stroke imaging software that could unlock wider use in the US.

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Expert Insights: At APhA 2025, Pharmacists Reaffirmed Their Essential Role in Patient Care

Pharmacy Times

Pharmacy professionals gathered at the American Pharmacists Association 2025 Annual Meeting and Exposition and discussed critical insights in interviews with Pharmacy Times.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

With a sign-off from Connecticut's health regulator in hand, the nonprofits say they have a clear path toward closing their merger within the next 30 days.

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AAN 2025: Fremanezumab Superior to Placebo in Reducing Monthly Migraine Days in Children and Adolescents

Pharmacy Times

Numerical differences were observed as early as Month 1.

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Fierce Healthcare - Untitled Article

Fierce Healthcare

Go-to conservative judiciary Matthew Kacsmaryk tossed requirements for greater nurse staffing levels, writing in his judgment that HHS had exceeded its statutory authority and congressional intent.

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AZ, Daiichi get EU okay for breast cancer drug Datroway

pharmaphorum

AstraZeneca and Daiichi Sankyo have claimed approval from the European Commission for Datroway, their TROP2-directed ADC for breast cancer.

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SGO 2025: The MRI Gap and How Race and Insurance Shape Cervical Cancer Treatment Timelines

Pharmacy Times

Sophie Jabban discusses research presented at the SGO Annual Meeting highlighting significant disparities in MRI access for patients with cervical cancer receiving chemoradiation, with delays linked to both race and insurance status, underscoring systemic barriers that may impact timely treatment.

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LogiPharma Europe 2025: An Innovative Journey

Pharmaceutical Commerce

The conferences opening keynote case study shares ways to elicit change that not only results in business growth and productivity, but a boost in patient connection as well.

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