Thu.Nov 21, 2024

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Tai Chi Intervention, Liver Disease Prevalence for People with OA | ACR Convergence

Drug Topics

Researchers explored the benefits of tai chi and prevalence of liver disease in patients with osteoarthritis.

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Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals

PharmaVoice

A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market.

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Despite Benefits, Mediterranean Diet Adherence in RA Remains Low | ACR Convergence

Drug Topics

The Mediterranean diet is largely considered one of the healthiest diets.

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After youth vaping surge, the U.K. moves to ban disposable e-cigarettes

STAT

LONDON — The stacks of brightly colored disposable e-cigarettes, touting flavors like cotton candy ice and greengrape melon and often looming over the not-dissimilar-looking candy displays, have become a commonplace sight in convenience stores in both the U.S. and the U.K.  But here, they’re on their way out.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Outcomes Vary When Cannabis Is Used for Pain Management in Rheumatic Disease | ACR Convergence

Drug Topics

Investigators evaluated the role that cannabis plays in pain management in different populations with rheumatic diseases.

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European Pharmaceutical Review Issue 5 2024

European Pharmaceutical Review

Articles in Issue 5 of European Pharmaceutical Review include: FOREWORD ICH Q6(R1): test criteria and specifications Dave Elder David P Elder Consultancy CELL & GENE THERAPY How automation and digital technologies will unlock the full potential of advanced therapies Dr Stephen Ward CGT Catapult Hydrogel encapsulation: unlocking the potential of cell therapies for targeted treatments Dr Stephen Harrington and Francis Karanu Likarda SUSTAINABILITY Transitioning to digital product information t

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Clinical Safety Data Show Switching Between Rituximab Biosimilars Does Not Increase Adverse Events

Pharmacy Times

There were 2 main types of switches, including switching to rituximab subcutaneous and switching among different intravenous rituximab treatments.

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Sotagliflozin’s Effect on BP Remains in T2D Regardless of Kidney Function | AHA 2024

Drug Topics

Research presented at American Heart Association’s 2024 Scientific Sessions examined the SGLT inhibitor’s effect on systolic blood pressure.

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Public Health Matters: Pharmacists as Frontline Health Providers: Collaborating for Better Patient Outcomes

Pharmacy Times

In this episode of Public Health Matters, Christina Madison discusses pharmacist-physician collaborations with Amina Abubakar and Stephen Lewis.

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Examining Impact of COVID-19 Diagnosis Timing on AF Progression | AHA 2024

Drug Topics

“[O]ur data do not support the hypothesis that early COVID resulted in more significant structural or electrical cardiac remodeling that would increase the likelihood of atrial fibrillation progression,” the authors said.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Antibody Drug Conjugate Targeting CLDN1 Receives FDA Fast Track Designation

Pharmacy Times

ALE.P02 could provide further treatment options for advanced or metastatic anti–claudin-1+ squamous cancers.

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Q&A: Chain Pharmacist Shares Keys to Success in Retail Settings

Drug Topics

James Rider, PharmD, shared reflections on his experiences as a pharmacy manager at CVS.

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Usage of AI With PET/CT Images Could Detect Impacts of Immunotherapy in Lung Cancer

Pharmacy Times

The risk of developing interstitial lung disease after immunotherapy was 6.5 times higher in individuals with high inflammation.

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Expiration of hospital-at-home, telehealth policies threatens nonprofit hospitals' recovery: Fitch

Fierce Healthcare

Not-for-profit hospital and health systems are slowly recovering from their worst year financially in 2022. | If federal lawmakers don't act to extend the Acute Hospital Care at Home program, which expires at the end of this year, it could dampen not-for-profit hospitals' nascent financial recovery, according to a new report from Fitch Ratings.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FDA Accepts sNDA for Darolutamide With ADT for Patients With mHSPC

Pharmacy Times

The supplemental new drug application (sNDA) is based on results from a phase 3 trial that enrolled patients with metastatic hormone-sensitive prostate cancer (mHSPC).

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Sweeping nonprofit House bill passes, healthcare groups turn attention to Senate

Fierce Healthcare

Legislation that gives a president wide-reaching power to financially harm any nonprofit an administration deems as terrorist supporting passed out of the House of Representatives Nov. 21. | H.R. 9495 passed in the House on Thursday. If signed into law, a president would be able to take a nonprofit's tax-exempt status away without due process, critics say.

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Intravenous Injections of Zanidatamab-Hrii Receives FDA Accelerated Approval for IHC+ BTC

Pharmacy Times

The indication is for adults with previously treated unresectable or metastatic HER2+ (IHC+) biliary tract cancer (BTC) as detected by an FDA-approved test.

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Pfizer, under pressure to change, names oncology head as new R&D chief

PharmaVoice

Chris Boshoff will replace Mikael Dolsten, who’s stepping down after 15 years leading research at the drugmaker.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Higher Composite Dietary Antioxidant Index Reduces Risk of Diabetes for Women

Pharmacy Times

Investigators also established a negative association with higher vitamin C intake and diabetes prevalence.

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From promise to reality: Unlocking the true business potential of genomic medicine

pharmaphorum

Explore how investing in genomic medicine can unlock the true business potential in the manufacturing and therapeutic areas. Understand the promise and reality of this cutting-edge field.

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Novel IVIG Formulation KIG10 Is Effective, Well Tolerated in Adults With Primary Immunodeficiency

Pharmacy Times

No acute serious bacterial infections were observed in a trial of patients with the debilitating immune disorder, a strong mark of safety and tolerability.

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Mass General Brigham primary care docs petition to unionize, citing burnout and lacking resources

Fierce Healthcare

Nearly 300 primary care doctors at Mass General Brigham (MGB) have petitioned to unionize. | The group, if approved, would join the Doctors Council, an affiliate of the Service Employees International Union representing attending physicians nationwide.

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Rusfertide Reduces Phlebotomy Need, Improves Symptom Control in Polycythemia Vera

Pharmacy Times

Rusfertide may sustain hematocrit levels in patients with polycythemia vera.

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Understanding endotoxin cartridge testing: frequently asked questions

European Pharmaceutical Review

Can cartridges be used as a standard method for assessing endotoxins across various sample types throughout the industry? A : FDA-licensed cartridges utilise the kinetic chromogenic method and are fit to test any type of endotoxin sample including, but not limited to, waters, raw materials, in-process samples, final products, medical devices and radiopharmaceuticals.

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Advancing Compounding Standards: Insights From the USP Compounding Implementation Workshop

Pharmacy Times

The workshop addressed trends, initiatives, and regulations for quality compounding.

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McKinsey nears $600m settlement with US government over role in opioid crisis

The Guardian - Pharmaceutical Industry

Consultancy firm accused of helping opioid makers boost sales, which allegedly contributed to deadly epidemic McKinsey is in the final stages of negotiating a deferred prosecution agreement to resolve a US criminal investigation into the consulting firm’s work helping opioid manufacturers boost sales that allegedly contributed to a deadly addiction epidemic , people familiar with the matter said.

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Versant enters obesity with new startup

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hullo! Today, some squiddy drug delivery, a leukemia deal between Kura Oncology and Kyowa Kiri, and a new GLP-1 startup from Versant Ventures.

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Gene therapy firm Kate Tx snapped up by Novartis for $1.1bn

pharmaphorum

Novartis buys gene therapy specialist Kate Therapeutics for $1.

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Kura Oncology partners Kyowa Kirin to advance AML treatment

Pharmaceutical Technology

Kura has partnered Kyowa Kirin in a strategic global collaboration for developing and commercialising oral ziftomenib to treat AML

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Solution Spotlight: Within3

pharmaphorum

Discover how Within3's community-driven platform helps businesses gather and utilise data effectively. Explore our solution spotlight for insights into their innovative approach.

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Famotidine vs. pantoprazole: Comparing uses, effectiveness, costs, and more

The Checkup by Singlecare

Famotidine and pantoprazole are medications commonly used to treat heartburn as well as other digestive problems, such as stomach ulcers, duodenal ulcers and the damage and inflammation of the esophagus (erosive esophagitis) caused by gastroesophageal reflux disease ( GERD ). While both drugs decrease acid production in the stomach, they differ in how they work, for what conditions they are best suited, their side effect profiles, and their availability (over-the-counter vs. prescription-only).

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Eisai debuts biliary tract cancer drug in Japan

pharmaphorum

Eisai has launched its new therapy for biliary tract cancer (BTC) Tasfygo in Japan, the first world market for the FGFR-targeting drug.

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Modernising drug delivery through gel-based technology

European Pharmaceutical Review

Accessibility, as well as optimised nutrient and medicine release, are the driving forces behind modernising drug delivery. With millions around the world struggling with dysphagia and other conditions that affect their ability to take pills and other medications, innovative delivery methods with gel-based platforms are necessary to promote greater accessibility and medication adherence.