Thu.Nov 21, 2024

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PMDD More Prevalent in RA, Leading to Worsened Mental Health | ACR Convergence

Drug Topics

Premenstrual Dysphoric Disorder is considered a psychiatric disorder and is associated with moderate to severe physical, affective, and behavioral symptoms.

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After youth vaping surge, the U.K. moves to ban disposable e-cigarettes

STAT

LONDON — The stacks of brightly colored disposable e-cigarettes, touting flavors like cotton candy ice and greengrape melon and often looming over the not-dissimilar-looking candy displays, have become a commonplace sight in convenience stores in both the U.S. and the U.K.  But here, they’re on their way out.

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Outcomes Vary When Cannabis Is Used for Pain Management in Rheumatic Disease | ACR Convergence

Drug Topics

Investigators evaluated the role that cannabis plays in pain management in different populations with rheumatic diseases.

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STAT+: A documentary about menopause has ‘misinformation’ and shouldn’t be used to educate docs, critics say

STAT

A dozen experts on women’s health are demanding the Federation of State Medical Boards remove a new documentary about menopause from its continuing medical education program over concerns the movie makes misleading and inaccurate statements about menopausal therapies. The film, called “ The M Factor: Shredding the Silence on Menopause ,” was released several weeks ago and can be seen on the Public Broadcasting System.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Examining Impact of COVID-19 Diagnosis Timing on AF Progression | AHA 2024

Drug Topics

“[O]ur data do not support the hypothesis that early COVID resulted in more significant structural or electrical cardiac remodeling that would increase the likelihood of atrial fibrillation progression,” the authors said.

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STAT+: Novartis buys gene therapy startup Kate Therapeutics, joining pursuit of muscular dystrophy treatment

STAT

Novartis said Thursday it purchased gene therapy startup Kate Therapeutics for up to $1.1 billion in upfront payments and milestones.  It’s a rare buyout for a field that has quieted over the last couple years, amid a wider biotech downturn and questions about both the effectiveness and profitability of these one-time treatments.  With the deal, Novartis will acquire a pipeline of preclinical gene therapies for three different genetic neuromuscular diseases, along with the under

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Opinion: It took years for my Black son to be diagnosed with cystic fibrosis. Then it happened to my family again

STAT

Twenty years ago, cystic fibrosis wasn’t a household term for me. Today, cystic fibrosis — a genetic disorder that causes a buildup of thick, sticky mucus that can damage organs, especially the lungs — has become a centerpiece of my family’s lives, sending me on an advocacy mission to improve diagnosis and care for all families, regardless of their racial or ethnic background.

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Keytruda represents almost half of Merck’s sales, and a new formulation could fend off rivals

PharmaVoice

A subcutaneous version of Merck’s Keytruda was as effective as the infused version in a late-stage study, but the company won’t be the first to market.

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STAT+: The state of biotech M&A 2024

STAT

This story first appeared in Adam’s Biotech Scorecard, a subscriber-only newsletter. STAT+ subscribers can sign up here to get it delivered to their inbox. Biotech M&A has been disappointing. Perhaps the trend will improve before we reach the holidays, but I can only opine on what’s transpired, and honestly, that’s not much.

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Public Health Matters: Pharmacists as Frontline Health Providers: Collaborating for Better Patient Outcomes

Pharmacy Times

In this episode of Public Health Matters, Christina Madison discusses pharmacist-physician collaborations with Amina Abubakar and Stephen Lewis.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Squid-inspired replacements for needles; Science Twitter and Bluesky

STAT

Good morning, I’m back! And I can barely believe all the news that happened while I was away. On vacation, my biggest concern was a broken milkshake machine at a highway McDonald’s. Why are they always broken?? (Addendum: Editors know things! Mine just sent me this story in the Verge about an update to the “right to repair” issues that have long plagued McDonald’s franchise owners and their machines.

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Novartis, after slimming down, boosts growth projection through the end of the decade

Fierce Pharma

As he introduced Novartis’ meet-the-management event Thursday in London, CEO Vas Narasimhan hammered home Novartis’ status as a streamlined, “pure-play, innovative medicines” company and the succes | Novartis has adjusted its compound annual growth rate expectation from 5%-plus to 6%-plus through 2029. The Swiss company cited the momentum of its current growth drivers, which have paved the way for a strong sales performance this year.

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Versant enters obesity with new startup

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hullo! Today, some squiddy drug delivery, a leukemia deal between Kura Oncology and Kyowa Kiri, and a new GLP-1 startup from Versant Ventures.

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Solution Spotlight: Within3

pharmaphorum

Discover how Within3's community-driven platform helps businesses gather and utilise data effectively. Explore our solution spotlight for insights into their innovative approach.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Your Guide to EGCG (Epigallocatechin-3-gallate)

Compounding Pharmacy of America

Recently, a compound known as EGCG has emerged as a leading weight loss supplement. This new supplement offers hope for many people struggling with myriad health issues, including obesity. However, weight loss isn’t the only benefit to this amazing supplement. The post Your Guide to EGCG (Epigallocatechin-3-gallate) appeared first on The Compounding Pharmacy of America.

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Tai Chi Intervention, Liver Disease Prevalence for People with OA | ACR Convergence

Drug Topics

Researchers explored the benefits of tai chi and prevalence of liver disease in patients with osteoarthritis.

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Novartis raises mid-term sales outlook on pipeline promise

pharmaphorum

Novartis has raised its guidance for sales growth out to 2029 on the strength of its pipeline and the potential of late-stage R&D assets

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Q&A: Chain Pharmacist Shares Keys to Success in Retail Settings

Drug Topics

James Rider, PharmD, shared reflections on his experiences as a pharmacy manager at CVS.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Kura Oncology partners Kyowa Kirin to advance AML treatment

Pharmaceutical Technology

Kura has partnered Kyowa Kirin in a strategic global collaboration for developing and commercialising oral ziftomenib to treat AML

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Despite Benefits, Mediterranean Diet Adherence in RA Remains Low | ACR Convergence

Drug Topics

The Mediterranean diet is largely considered one of the healthiest diets.

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Sweeping nonprofit House bill passes, healthcare groups turn attention to Senate

Fierce Healthcare

Legislation that gives a president wide-reaching power to financially harm any nonprofit an administration deems as terrorist supporting passed out of the House of Representatives Nov. 21. | H.R. 9495 passed in the House on Thursday. If signed into law, a president would be able to take a nonprofit's tax-exempt status away without due process, critics say.

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23andMe stock sell-off adds to its woes

pharmaphorum

Shares in genetic testing company 23andMe continue to slide after prominent investors announce plans to sell their stakes.

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Intravenous Injections of Zanidatamab-Hrii Receives FDA Accelerated Approval for IHC+ BTC

Pharmacy Times

The indication is for adults with previously treated unresectable or metastatic HER2+ (IHC+) biliary tract cancer (BTC) as detected by an FDA-approved test.

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Eisai debuts biliary tract cancer drug in Japan

pharmaphorum

Eisai has launched its new therapy for biliary tract cancer (BTC) Tasfygo in Japan, the first world market for the FGFR-targeting drug.

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Novel IVIG Formulation KIG10 Is Effective, Well Tolerated in Adults With Primary Immunodeficiency

Pharmacy Times

No acute serious bacterial infections were observed in a trial of patients with the debilitating immune disorder, a strong mark of safety and tolerability.

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FDA chief: AI adoption driven by financial reasons, not patient benefits

STAT

You’re reading the web edition of STAT’s Health Tech newsletter, our guide to how technology is transforming the life sciences.  Sign up to get it  delivered in your inbox every Tuesday and Thursday. Robert Califf: Clinical care should drive AI adoption It’s day two of the FDA’s advisory committee meeting on regulating generative artificial intelligence tools.

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FDA Accepts sNDA for Darolutamide With ADT for Patients With mHSPC

Pharmacy Times

The supplemental new drug application (sNDA) is based on results from a phase 3 trial that enrolled patients with metastatic hormone-sensitive prostate cancer (mHSPC).

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Roche's Vabysmo shows potential to treat eye disorder common in Asia

Fierce Pharma

Few pharmaceutical products have taken the market by storm like Roche’s Vabysmo. | Interim results from a late-stage trial of Roche's Vabysmo on Asian patients with polypoidal choroidal vasculopathy suggest that the injected treatment is effective. After 16 weeks, patients showed vision improvement which was equivalent to reading roughly one and a half more lines on an eye chart.

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Clinical Safety Data Show Switching Between Rituximab Biosimilars Does Not Increase Adverse Events

Pharmacy Times

There were 2 main types of switches, including switching to rituximab subcutaneous and switching among different intravenous rituximab treatments.

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Expiration of hospital-at-home, telehealth policies threatens nonprofit hospitals' recovery: Fitch

Fierce Healthcare

Not-for-profit hospital and health systems are slowly recovering from their worst year financially in 2022. | If federal lawmakers don't act to extend the Acute Hospital Care at Home program, which expires at the end of this year, it could dampen not-for-profit hospitals' nascent financial recovery, according to a new report from Fitch Ratings.

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Pharmacy Students Using TikTok to Take Learning to the Next Level

Pharmacy Times

Through an assignment to create a TikTok infomercial, students master new concepts and have positive educational experiences via social media.

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Fierce Pharma Asia—Big Pharma’s China layoffs, CSL's site closure and Kyowa Kirin's oncology deal

Fierce Pharma

Merck and Johnson & Johnson are cutting staffers in China as they face local headwinds | Merck and Johnson & Johnson are cutting staffers in China as they face local headwinds, according to reports. Australia’s CSL is winding down operations at a cell and gene therapy R&D site in California. Kyowa Kirin inked a commercialization and development deal with Kuro Oncology.

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Antibody Drug Conjugate Targeting CLDN1 Receives FDA Fast Track Designation

Pharmacy Times

ALE.P02 could provide further treatment options for advanced or metastatic anti–claudin-1+ squamous cancers.

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