Wed.Mar 13, 2024

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How Daylight Saving Time Increases Overall Health Risks

Drug Topics

Recent studies on daylight saving time’s association with increased health risks have heightened the debate on whether to observe the biannual event or switch to one universal time.

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Little Pills, Big Risks: The Untold Dangers of Referring to Low-Dose Aspirin as 'Baby Aspirin’

Pharmacy Times

Aspirin, known as acetylsalicylic acid, has been marketed in ways that have de-emphasized potential risks to children.

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CDC Says US Will Transition to Trivalent Vaccines Next Flu Season

Drug Topics

Since changes in vaccine composition can sometimes lead to confusion or misinformation, effective communication is crucial to promote vaccine uptake.

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STAT+: Hemophilia gene therapies arrived after 40 years of struggle. Where are the patients?

STAT

As a boy growing up with hemophilia A, Noah Frederick reserved the end of his annual checkups to talk about new technologies. His doctor walked through various experimental approaches for the bleeding disorder and, invariably, gene therapy. It was coming, he always said, in your lifetime. Last year, it finally arrived. But Frederick, now a 23-year-old software engineer, isn’t sure he’ll get it.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Psilocybin Analog for Treatment of Depression Receives FDA Breakthrough Therapy Designation

Drug Topics

Cybin’s proprietary deuterated psilocybin analog, CYB003, provided robust and sustained improvements in depression symptoms in a phase 2 study.

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STAT+: Small studies offer hope CAR-T can fight an aggressive brain cancer

STAT

A series of new studies are raising hopes that CAR-T , a process in which treatments are made by genetically editing a patient’s own white blood cells, can eventually be used to treat an incurable and deadly type of brain cancer, called glioblastoma multiforme, or GBM. In the most dramatic result, from a three-person study conducted by researchers at Massachusetts General Hospital, a 72-year-old man saw his tumor shrink 18.5% in just two days and then decrease further over the next two mo

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STAT+: Hospitals struggle to validate AI-generated clinical summaries. ‘It’s a bit chaotic’

STAT

Rob Bart remembers what it felt like, the moment of discovery. As an intern at Duke University Medical Center in the ’90s, he’d sometimes be tasked with poring through a patient’s medical history to uncover the cause of their latest hospitalization. Back then, the stacks of paper records could tower 18 inches tall. “I can remember that needle in the haystack feeling,” said Bart, now chief medical information officer at the University of Pittsburgh Medical Cente

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Pharmacy Focus: Limited Series: Celebrity Endorsements in Ozempic

Pharmacy Times

This podcast episode discussed the impact of celebrity endorsements on trends in weight loss drugs like Ozempic, body image issues, and the role of pharmacists in educating patients on appropriate use of GLP-1 medications for weight management and chronic diseases.

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Eli Lilly partners with Amazon Pharmacy for home delivery of its weight loss, diabetes and migraine drugs

Fierce Healthcare

Eli Lilly is partnering with Amazon's pharmacy unit to offer home delivery for diabetes, migraine and obesity medications, including GLP-1 weight loss drug Zepbound. | Eli Lilly is partnering with Amazon's pharmacy unit to offer home delivery for diabetes, migraine and obesity medications, including GLP-1 weight loss drug Zepbound.

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Biotech trade group pledges support for BIOSECURE Act, plans to boot member WuXi AppTec

Fierce Pharma

As CDMO giants Wuxi AppTec and WuXi Biologics come under mounting scrutiny for their alleged ties to Chinese government officials, they are losing a key ally in Washington, D.C. | As CDMO giants Wuxi AppTec and WuXi Biologics come under mounting scrutiny for their alleged ties to Chinese government officials, they are losing a key ally in Washington, D.C.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Study: Lymphoma Patients Recover Longer for Pneumonia

Pharmacy Times

Furthermore, the study authors indicated that patients with lymphoma and community-acquired pneumonia have broader dysregulated responses.

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HiLabs closes $39M funding round as company enters 'next phase of growth'

Fierce Healthcare

HiLabs, an AI-powered health tech company helping plans improve member experience, raised $39 million in a series B financing round, led by growth equity firm Denali Growth Partners and VC firm Eig | An AI-powered health tech company helping drive down operational costs for healthcare organizations and improving member experience for payers pocketed $39 million in fresh funding.

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GZ17-6.02 Effective in Killing Multiple Myeloma Cells, Other Benefits When Combined With Bortezomib

Pharmacy Times

The combination of GZ17-6.02 and bortezomib reduced of HDAC, and as a result ATG13 phosphorylation was enhanced, BAK levels increased, and BCL-XL levels were reduced.

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STAT+: In large trial, Guardant Health’s blood test detects colon cancer, but less reliably at earliest or precancerous stages

STAT

Doctors have been eagerly waiting for data on Guardant Health’s new blood-based colorectal cancer screening test, the Shield test. The hope has been that Guardant would be able to achieve an elusive goal in colorectal cancer screening: catch incipient or early colorectal cancer using nothing more than two vials of blood. Those hopes were partially fulfilled on Wednesday.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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FDA flags early deaths in CAR-T myeloma trials for J&J and Legend’s Carvykti, Bristol Myers’ Abecma

Fierce Pharma

The FDA has raised concerns about early clinical trial deaths as part of two applications that aim to move the CAR-T therapies Carvykti and Abecma into earlier lines of treatment for multiple myelo | Ahead of an important advisory committee meeting, the FDA has raised concerns about early trial deaths for multiple myeloma cell therapies. At the meeting, experts will discuss applications that aim to move the CAR-T therapies Carvykti and Abecma into earlier lines of treatment.

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Transitioning PROs from paper to digital: Maintaining data integrity and patient experience

pharmaphorum

Transitioning patient-reported outcomes (PROs) from paper to digital (ePRO) is crucial for maintaining data integrity and improving the patient experience. Learn how to seamlessly make this transition and optimise your data collection process.

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STAT+: RaDonda Vaught, former Vanderbilt nurse who accidentally killed patient, says hospital issues contributed, too

STAT

Speaking before a virtual audience of CommonSpirit Health employees, RaDonda Vaught, the former nurse who accidentally killed a patient by administering the wrong medication, listed the outside factors she claims contributed to her fatal error. Among them: a missing drug order, a faulty medication dispenser, and a hurricane that hampered the drug supply.

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Takeda winds down manufacturing and R&D operations in Austria after gene therapy pivot, plots 190 layoffs

Fierce Pharma

After Takeda’s unsuccessful attempt to sell an Austrian manufacturing and development site, the Japan-based company is calling it quits on much of the operations at the facility. | After Takeda’s unsuccessful attempt to sell an Austrian manufacturing and development site, the Japan-based company is calling it quits on much of the operations at the facility.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Digitalising supply chains may be the zeitgeist, but let’s not forget about the power of human partnerships

pharmaphorum

Digitalising supply chains may be the zeitgeist, but let’s not forget about the power of human partnerships Mike.

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STAT+: AI health care companies say they’ll keep humans in the loop. But what does that actually mean?

STAT

Developers of artificial intelligence models slowly making their way into medicine have long parried ethical concerns with assertions that clinical staff must review tech’s suggestions before they are acted on. That “human in the loop” is meant to be a backstop preventing potential medical errors conjured up by a flawed algorithm from harming patients.

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J&J's Duato nets major raise to $28.4M, jumps to top of pharma CEO pay rankings

Fierce Pharma

It didn’t take long for Johnson & Johnson CEO Joaquin Duato to catch up to his predecessor. | It didn’t take long for Johnson & Johnson CEO Joaquin Duato to catch up to his predecessor. After paying Duato $13.1 million in his first year as CEO, the pharma giant more than doubled his compensation to $28.4 million last year, according to a regulatory filing.

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Lilly adds Amazon Pharmacy to LillyDirect DTC channel

pharmaphorum

Amazon Pharmacy will provide dispensing for Eli Lilly’s recently launched direct-to-consumer LillyDirect channel, covering obesity, diabetes, and migraine drugs.

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Appeals court affirms Arkansas law against drugmakers' 340B contract pharmacy restrictions

Fierce Healthcare

A federal appellate court upheld an Arkansas law prohibiting drugmakers from restricting 340B drug discounts for providers using contract pharmacies, potentially setting up other states to pass sim | A pharmaceutical industry trade group had argued that the state's 2021 law was preempted by the federal legislation outlining the drug discount program.

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BaseCamp unveils improved protein structure prediction model

pharmaphorum

Basecamp Research launches BaseFold, a deep learning model that it says surpasses benchmark tool AlphaFold2 and should accelerate AI-based drug discovery

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California Wildfires in the 2010s Exacerbated Psychotropic Medication Prescriptions

Drug Topics

Researchers studied the effect of wildfires on mental health in California from 2011 to 2018.

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Clover Health trends upwards after fourth quarter earnings, posts adjusted EBITDA loss of $19M

Fierce Healthcare

Insurtech Clover Health execs are reiterating their path to profitability is headed in the right direction. | Supported by a much-improved medical cost ratio, Clover Health execs expect to hit adjusted EBITDA profitability this year.

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Prilenia eyes 2025 launch for Huntington’s drug pridopidine

pharmaphorum

Prilenia Therapeutics is planning to file its Huntington’s disease drug pridopidine in the EU shortly, after mixed results in a phase 3 trial.

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STAT+: Pharma loses a key battle over a state law concerning 340B pharmacies

STAT

In a setback to the pharmaceutical industry, a U.S. appeals court has upheld an Arkansas law that allows hospitals participating in a controversial federal discount program to ship medicines to certain pharmacies. As a result, other states can now be expected to pursue similar laws. The closely watched decision comes amid a long-running battle over the program, which was designed three decades ago to help hospitals and clinics care for low-income and rural patients.

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SABATO Trial: Implications for Pharmacists in Staphylococcus Aureus Treatment

Pharmacy Times

Study results indicate early swap to oral antibiotics in Staphylococcus aureus bacteremia is just as effective.

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STAT+: BIO severs ties with WuXi in the face of U.S. government concerns over China

STAT

WASHINGTON — The Biotechnology Innovation Organization, an industry trade group, is cutting ties with Chinese company WuXi in response to increasing U.S. government scrutiny of it and other Chinese companies, according to a BIO press release shared with STAT on Wednesday. It’s an about-face for a lobbying organization that recently was willing to defend WuXi against attacks, and it’s a sign that the U.S. biotechnology industry will have to make do without a company that it h

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Mirum scores second FDA nod for rare liver disease drug Livmarli, this one to treat PFIC

Fierce Pharma

FDA has OKed Mirum’s Livmarli to treat the rare liver disease PFIC.

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Opinion: Good health care price transparency rules are at risk if Congress doesn’t act

STAT

Consider shopping for cereal in the grocery store. Buyers easily know how many grams of sugar and calories are in a serving, as well as how much the box costs, before they get to the checkout line. Yet in the U.S. health care market, this often isn’t the case. Prices are both high and highly variable as well as difficult to observe. I’m an economics professor.

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Common Residency Interview Questions from the 2024 Match 

Board Vitals - Pharmacist

As candidates prepare for the rigorous residency interview season, it’s essential to anticipate the types of questions that may arise during these pivotal conversations. While the questions asked will vary by program and specialty, certain themes and questions tend to recur across the board, and there are some questions that appear more than others.

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