Tue.Mar 12, 2024

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A New Study Finds That Ruxolitinib Cream 1.5% Is Effective for Most Patients With HS

Pharmacy Times

The cream significantly reduced abscesses and inflammatory nodules, reaffirming its efficacy as a maintenance option for HS.

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Opinion: No parent who has seen the children I’ve treated for measles would refuse a vaccine

STAT

Over the past year, I have watched many children die of measles. In the final stages, little lungs, filled with fluid and racked with inflammation, struggle for oxygen. The victims breathe faster and faster, gasping for air until, exhausted, they stop.

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HIMSS24: 'Fasten your seatbelts'—Hackensack Meridian CEO predicts acceleration of gen AI to help healthcare workforce

Fierce Healthcare

ORLANDO — It's almost impossible to have a conversation at HIMSS24 without the topic of artificial intelligence or generative AI coming up. | How will the conversations about AI in healthcare change by next year's HIMSS conference? Hackensack Meridian CEO Robert Garrett predicts that pilot projects underway now will roll out into practice.

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Rigid rules at methadone clinics are jeopardizing patients’ path to recovery from opioid addiction

STAT

DETROIT — Every morning, Rebecca Smith, nursing a surgically repaired knee, carefully walks down the hallway of her brutalist brick apartment building, takes the elevator one floor to the lobby, and negotiates the sharply angled driveway outside. There, she waits for an Uber to take her to the last place she wants to go: her methadone clinic.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Frazier Healthcare Partners acquires RevSpring, plans to fuel growth with new investments

Fierce Healthcare

Nashville, Tennessee-based patient engagement and payment technology company RevSpring has found itself with new investor ownership that promises to ramp up the business. | The patient engagement and payment technology company's new investor owner promised to bring "additional resources to accelerate and enhance RevSpring’s offerings.

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After Amylyx ALS trial failure, patients share disappointment and fear — but some hope

STAT

The news last week that a Phase 3 trial of Amylyx Pharmaceuticals’ amyotrophic lateral sclerosis drug — marketed as Relyvrio — failed to benefit patients compared to placebo hit the ALS patient community hard. An earlier study had shown that patients who took the drug for six months experienced significantly less decline than people on the placebo in physical function, such as the ability to speak, use utensils, or climb stairs.

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More Trending

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STAT+: Researchers create talking throat patch for people with voice disorders

STAT

Researchers at the University of California, Los Angeles have built a soft, adhesive patch capable of turning throat movements into speech. The patch, written about in a paper published in Nature Communications on Tuesday, is made out of a material that converts motion into electricity. This material, developed by the UCLA team in 2021, could be a gamechanger for sensors and wearables limited by their power sources.

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A Pharmacist’s Guide to Continuous Glucose Monitoring

Pharmacy Times

This guide discusses the integration of continuous glucose monitoring (CGM) technology into clinical practice, emphasizing the role of pharmacists in selecting and optimizing CGM devices for patients.

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STAT+: First medicine developed to treat MASH expected to be approved soon

STAT

The Food and Drug Administration is expected to approve the first medicine developed specifically to treat the serious liver disease known as MASH as soon as this week. The pill, called resmetirom, is made by Madrigal Pharmaceuticals. Metabolic dysfunction-associated steatohepatitis, or MASH and previously called NASH , is often associated with obesity.

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Why gut bacteria is the next frontier in medicine

pharmaphorum

Discover why gut bacteria are considered the next frontier in medicine in this informative article. Learn about the importance of the microbiome, its impact on health, and how it relates to conditions like Clostridiales difficile.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Delta 8 THC use reported by 11% of high school seniors

STAT

WASHINGTON — In the last year, an estimated 11% of high school seniors have used Delta 8 THC, according to a new report published Tuesday in the Journal of the American Medical Association. Delta 8 THC is a quasi-legal psychoactive version of cannabis, which has skyrocketed in popularity after a loophole found in a 2018 federal law allowed it to be sold nationwide without the same restrictions placed on traditional marijuana.

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Behavioral and veterans' health among key priorities in Biden's budget

Fierce Healthcare

President Joe Biden's 2025 budget did not just touch upon cybersecurity, the drug price negotiation program and Medicare solvency, as the plan also suggested policy for mental health, health equity | Many significant policy items in Biden's proposed 2025 fiscal year budget don't grab the initial headlines, but he's looking to make strides in mental health, substance use disorder and maternal health.

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Longevity Science Does Not Only Focus on Living Longer

Pharmacy Times

Health span, wealth span, advocacy, and ethics are all burgeoning topics within the field of longevity.

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Change Healthcare cyberattack isn't threatening major for-profit systems' bottom lines, execs say

Fierce Healthcare

The nation’s largest for-profit health systems reassured investors Tuesday that the Change Healthcare cyberattack, though disruptive in the short term, is a “transitory” event that’s unlikely to ha | Senior leadership at HCA Healthcare, Tenet Healthcare and Universal Health Systems say their organizations are shielded from the liquidity and administrative issues that are plaguing providers across the country.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Patients With T2D Often Lack Knowledge That Could Help Manage Disease

Drug Topics

The implementation of targeted educational interventions might improve knowledge gaps, which pose great risk to patients, in type 2 diabetes (T2D) management.

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HIMSS24: CodaMetrix pockets $40M series B to build out AI-based revenue cycle tools

Fierce Healthcare

ORLANDO — CodaMetrix, a company that provides automated coding technology for healthcare billing and revenue cycle management, picked up $40 million in fresh funding to build out its AI-based | odaMetrix, a company that provides automated coding technology for healthcare billing and revenue cycle management, picked up $40 million in fresh funding to build out its AI-based soultions.

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J&J Submits sBLA To FDA for Guselkumab in Ulcerative Colitis

Pharmacy Times

Individuals included in the study reported positive changes in fatigue, and disease activity displayed endoscopic and histologic remission.

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Changing Faces: Agency, consultancy, and investor hires from February 2024

pharmaphorum

Discover the latest agency, consultancy, and investor hires from February 2024, including personnel from OVID Health, Avalere, WE Communications, and Eurozeo. Stay updated with industry movements and key players.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Sotagliflozin May Steal the Spotlight in Heart Failure, but Questions Remain

Pharmacy Times

Although newly approved, there is some debate regarding the benefits and populations in which sotagliflozin will be the most effective.

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Avoiding the data swamp: The transformative power of AI

pharmaphorum

In the latest episode of the pharmaphorum podcast, host Nicole Raleigh speaks (virtually) with Nathan Clark, founder and CEO of Ganymede, a modern data platform and Cloud infrastructure for science, to discuss the evolving role of the Cloud in biopharma and some rather revolutionary tools in AI drug discovery.

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Amid Moderna's 'transition year,' CEO Stéphane Bancel's total pay fell by about 5%

Fierce Pharma

Despite Moderna’s efforts to prove its mRNA thesis beyond COVID-19 in 2023, the post-pandemic hangover took a toll on the company. | Despite Moderna’s efforts to prove its mRNA thesis beyond COVID-19 in 2023, the post-pandemic hangover took a heavy toll on the company. In turn, much of the company’s top brass—including CEO Stéphane Bancel—saw their total compensation fall for the year.

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Review calls for action on bias with medical devices

pharmaphorum

Healthcare systems need to address the impact of racial and ethnic biases in the design and use of medical devices, says an independent UK review.

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STAT+: For-profit health system’s Mass. hospitals teetering on the brink of financial disaster

STAT

Steward Health Care’s Massachusetts hospitals are on the brink of financial disaster. But in many important ways, Steward’s troubles are just a symptom of a larger crisis engulfing the entire industry. While Steward’s for-profit ownership structure put its hospitals at a disadvantage, many health care executives say the state’s entire network of hospitals  is approaching a capacity shortage  not seen since the early days of the Covid-19 pandemic.

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Pfizer aims Adcetris for expansion into large B-cell lymphoma after trial win

Fierce Pharma

The antibody-drug conjugate (ADC) Adcetris has given Pfizer’s oncology department its first pivotal trial win from the legacy Seagen portfolio since the $43 billion merger. | The antibody-drug conjugate Adcetris has given Pfizer’s oncology department its first pivotal trial win from the legacy Seagen portfolio since the $43 billion merger.

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Older Adults’ Experience with Opioid Use, Deprescribing

Pharmaceutical Commerce

A qualitative study explores how these drugs are impacting these patients’ lives, while digging deeper into the possibility of deprescribing, with insight from primary care physicians.

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Acadia to end Nuplazid testing after schizophrenia trial flop and years of failed expansion efforts

Fierce Pharma

Acacia Pharmaceuticals is calling it quits on future testing of Nuplazid after a string of expansion efforts have come up short. | The company will not conduct any further clinical trials of the drug, which is currently approved to treat Parkinson’s disease psychosis. The decision comes after years of failed expansion bids in other uses.

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STAT+: Pharmalittle: We’re reading about a failed schizophrenia drug trial, a Pfizer cancer drug, and more

STAT

Top of the morning to you, and a fine one it is. Sunny skies and a crisp breeze are wafting over the Pharmalot campus, where the official mascots are roaming about in search of noshes and amusement. This marks a welcome change from the unusual high winds the day before. So we have decided to celebrate by firing up the coffee kettle to brew another cup of stimulation.

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Do probiotics make you poop?

The Checkup by Singlecare

Probiotics are known for their ability to help support a healthy gut microbiome, regulate digestion, improve stool patterns, and decrease gas and bloating. But if you’ve ever taken probiotic supplements, you’re likely aware of the potentially uncomfortable, to put it delicately, side effects of starting a new probiotic. With so many strains and varieties available for purchase, it’s hard to know which probiotics are right for you—and what’s normal to experience in the bathroom as your body adjus

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Pfizer’s Velsipity heading for NHS use in ulcerative colitis

pharmaphorum

Up to 25,000 patients in England with ulcerative colitis are eligible for treatment with Pfizer’s Velsipity after NICE backed use of the drug on the same day as its MHRA approval.

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Terns scores FDA orphan designation for CML therapy

Pharmaceutical Technology

TERN-701 is a BCR-ABL tyrosine-kinase inhibitor being studied in a Phase I study, with data expected in H2 this year.

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Acadia pulls trials of pimavanserin after schizophrenia fail

pharmaphorum

Acadia Pharma has abandoned plans to develop Nuplazid for additional indications after the drug failed a phase 3 trial in schizophrenia.

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Adopting New Manufacturing Technologies

Pharmaceutical Commerce

A sit-down with Groovy Singh, CEO of Bright Green Corporation, who describes the waves in the global supply chain the company is making after being authorized to grow cannabis, along with cannabis-related products.

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AAD: Sanofi showcases data on possible Dupixent successor

pharmaphorum

Sanofi says OX40L inhibitor amlitelimab could be a ‘best-in-class’ maintenance therapy for atopic dermatitis after reporting new phase 2b data

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