Tue.Dec 17, 2024

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High Comorbidity Burden in Resistant, Refractory Migraine Vs Chronic Migraine

Drug Topics

Treatment of comorbidities may help patients overcome resistance or refractoriness to migraine therapies.

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Men With History of Cannabis Use Have Less Cognitive Decline From Early Adulthood to Late Midlife

Pharmacy Times

The investigators also find that age of initiation and frequent use were not associated with a greater age-related cognitive decline.

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CMS sunsets Medicare Advantage value-based model, citing billions in costs

Fierce Healthcare

The Centers for Medicare & Medicaid Services (CMS) is discontinuing the Medicare Advantage (MA) Value-Based Insurance Design model at the end of 2025. | The Value-Based Insurance Design model for Medicare Advantage plans will be terminated at the end of next year.

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Paxlovid’s Double-Edged Sword: Treating COVID-19 and the Risk of Viral Load Rebound

Pharmacy Times

The conversation of VLR has sparked a discussion as to whether or not other COVID-19 treatment agents are associated with a surge in symptoms and if so, how those agents compare with the rebound effect of nirmatrelvir/ritonavir.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Does Mounjaro need to be refrigerated?

The Checkup by Singlecare

Like semaglutide, Mounjaro (tirzepatide) is a once-a-week injectable medication that is FDA approved for helping manage blood sugar levels in those with Type 2 diabetes. It mimics two gastrointestinal hormones: glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). So, the active ingredient can also be prescribed for weight loss or obesity, combined with diet and exercise, under its licensed brand name Zepbound.

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Nuclear Isotopes Could Help Address Challenges in Oncology Clinical Trials

Pharmacy Times

The radiation emerging from these isotopes can be used in 2 different ways in cancer trials: imaging (detection of tumors) and therapy (destruction of tumors).

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More Trending

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Novo Nordisk invests $1.2bn in new Denmark facility

Pharmaceutical Technology

Construction has already begun on the Ozempic-producers new Denmark production facility and 40,000m2 warehouse.

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FDA Approves Crinecerfont for Adult, Pediatric Patients with Congenital Adrenal Hyperplasia

Pharmacy Times

The decision is based on positive results from the CAHtalyst trials, which both met their primary and secondary end points.

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FDA rejects J&J's subcutaneous Rybrevant filing and AZ's full approval bid for Andexxa

Fierce Pharma

Johnson & Johnson has received coal in its stocking from the FDA as manufacturing issues have tripped up the companys attempt to gain approval of its subcutaneous version of lung cancer drug R | The FDA has sent complete response letters to Johnson & Johnson and AstraZeneca, rejecting J&J's application for subcutaneous Rybrevant and AZ's bid for a full approval of Andexxa.

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Wearing CGMs Can Help Student Pharmacists Improve Counseling Ability

Drug Topics

Student pharmacists who wore a continuous glucose monitor had a higher average counseling score during an encounter with a patient and a higher overall confidence score.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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2025 outlook: Employers face yet another year of healthcare cost increases

Fierce Healthcare

Employers are bracing for healthcare costs to spike yet again in 2025, and that's likely to push these firms to pursue significant changes, experts said. | Employers are bracing for healthcare costs to spike yet again in 2025, and that's likely to push these firms to pursue significant changes, experts said.

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Q&A: Pharmacist’s Perspective on How Biosimilars Will Impact the Field in the Coming Years

Drug Topics

A conversation with Chelsee Jensen, PharmD, BCPS, senior pharmacy specialist at the Mayo Clinic.

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Regeneron's Eylea HD passes key test in retinal vein occlusion, teeing up 2025 FDA filing as Eylea threats mount

Fierce Pharma

With Eylea biosimilar competition creeping in and Roches Vabsymo jockeying for market share in key indications, Regeneron is racing to carve out a new market for the high-dose version of its block | High-dose Eylea demonstrated non-inferiority to the original version of the drug in patients with macular edema following retinal vein occlusion, an indication Eylea has held for a decade.

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Triptans Associated With Adverse Events Across Organ Systems

Drug Topics

Triptans are used to treat acute migraine and cluster headaches.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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After studies flag possible link between Novo's Ozempic and rare eye disorder, Danish agency calls for probe

Fierce Pharma

Its not a new question, but it is one that is gaining increased traction: Is there a link between Novo Nordisks diabetes superstar Ozempic and blindness? | After the recent release of two independent studies from the University of Southern Denmark suggested the use of Ozempic increases patients' chances of developing a rare eye disorder, the Danish Medicines Agency has asked European officials to investigate.

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Q&A: How Pharmacists Can Help Patients with COPD, Inhaler Misuse | ASHP Midyear

Drug Topics

Drug Topics met with Lourdes Cross, PharmD, BCACP, CDCES, to discuss pharmacists role in managing patients chronic obstructive pulmonary disease.

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STAT+: FDA deputy commissioner Namandjé Bumpus to leave agency

STAT

Namandjé Bumpus, principal deputy commissioner of the Food and Drug Administration, is leaving the agency. Commissioner Robert Califf shared the news with staff Tuesday morning, according to an email reviewed by STAT.

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Study backs Closed Loop's drug+digital blood pressure plan

pharmaphorum

Closed Loop Medicine's smartphone app for blood pressure monitoring has shown proof-of-concept in the Cure-19 study.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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ASH 2024: Nuvisertib Demonstrates Durable Response in Relapsed/Refractory Myelofibrosis

Pharmacy Times

Firas El Chaer, MD, discusses newly-presented data at ASH demonstrating nuvisertib's effectiveness in myelofibrosis.

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CTO Europe 2024: keep the burden of trials away from patients, say experts

Pharmaceutical Technology

The two-day event included talks on subjects ranging from how to best utilise AI to how to build a stable CRO.

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Camber Pharmaceuticals Announces Addition of Erlotinib Tablets

Pharmacy Times

Erlotinib Tablets are available in 25 mg, 100 mg, and 150 mg strengths, packaged in 30-count bottles.

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2025 outlook: What's next for AI scribes and virtual care

Fierce Healthcare

In 2025, the healthcare industry will expect more out of artificial intelligence. | Fierce Healthcare interviewed nine executives on what the AI scribe and telehealth markets will look like in 2025. Executives expect AI companies to consolidate and for virtual care to latch onto the momentum of the technology to transform care.

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Pathways to Improve Overall Survival in Myelofibrosis: Finding Alternate Trial End Points

Pharmacy Times

Measuring end points such as molecular response, cytokines, and histomorphometry may show a greater range of benefits.

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Pfizer expects $1B hit from IRA's Part D redesign and no major M&A in 2025

Fierce Pharma

After pulling off a surprise third-quarter beat and full-year guidance raise amid shareholder activism earlier this year, Pfizer now expects its 2025 revenues to come in the same range as in 2024.< | After pulling off a surprise third-quarter beat and full-year guidance raise amid shareholder activism earlier this year, Pfizer now expects its 2025 revenues to come in the same range as in 2024.

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ASHP Midyear: Pharmacist Emphasizes Individualized Approach to Antiplatelet Therapy Management

Pharmacy Times

Snehal Bhatt discusess the need to individualize antiplatelet therapy decisions based on a comprehensive assessment of each patient's unique risk factors for thrombosis and bleeding.

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Top tips for effective digital transformation and closed loop medicines management

Hospital Pharmacy Europe

S erious adverse drug events are unfortunately common in hospitals and can occur across all stages of the medication delivery process. Here, Francine de Stoppelaar shares her top tips for implementing effective closed loop medicines management systems as part of a hospitals digital transformation journey to enhance patient care, reduce expenditures and build a sustainable future for healthcare.

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Study Finds Asthma Is Common Among Children With Primary Ciliary Dyskinesia

Pharmacy Times

The authors note that routine screening in patients with primary ciliary dyskinesia to help identify undiagnosed asthma.

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China NMPA approves MSD’s KEYTRUDA for stages of NSCLC

Pharmaceutical Technology

China National Medical Products Administration (NMPA) has approved MSDs KEYTRUDA for treating certain non-small cell lung cancer (NSCLC).

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Investigators Develop Training Tool to Improve Prescriber-Patient Communication About Biosimilars

Pharmacy Times

The tool is designed to address the nocebo effect, which was a concern of prescribers and other health care professionals.

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Biotech bounces back as venture funding grows $3.8m from 2023 to 2024YTD

Pharmaceutical Technology

However, caution persists:166 of 785 US venture-backed companies with an innovator drug in development have not raised capital since 2021.

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Sacituzumab Govitecan-hziy Receives FDA Breakthrough Therapy Designation for Extensive-Stage Small Cell Lung Cancer Treatment

Pharmacy Times

Abstract data presented in September demonstrate that the drug elicited strong antitumor activity in the second line in both platinum-sensitive and -resistant patients.

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GSK’s lung cancer therapy gains EMA PRIME designation

Pharmaceutical Technology

GSKs GSK227 has gained Priority Medicines (PRIME) designation from the EMA for the treatment of relapsed ES-SCLC.

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When to Call, When to Counsel: Fluoroquinolone Tendinopathy

Pharmacy Times

A collaborative health care approach enhances patient outcomes and supports informed decision-making in antibiotic management.

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