Wed.Dec 04, 2024

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UnitedHealthcare CEO Brian Thompson fatally shot in Manhattan: reports

Fierce Healthcare

UnitedHealth Group abruptly ended its investor day event on Wednesday morning as new reports surfaced that the CEO of its health plan division had been fatally shot. | UnitedHealth Group abruptly ended its investor day event on Wednesday morning as news reports surfaced that the CEO of its health plan division had been fatally shot.

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Genmab expands its pipeline with $630m Scancell deal

pharmaphorum

Genmab has licensed another anti-glycan antibody for cancer from UK biotech Scancell as it continues to expand its in-house pipeline.

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Trending Sources

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Healthcare industry needs to get a grip on AI governance in 2025, ECRI warns

Fierce Healthcare

Risks with AI-enabled health technologies topped the list of the ECRI Institute's annual ranking of health technology hazards. | A well-known safety group debuted its annual report that lays out the top 10 health technology risks for the upcoming year. The risks of AI perpetuating bias or hallucinating answers to medical questions tops the list of risks for 2025.

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‘Leptin’s last chance’: Mouse study says infamous weight loss drug failure could boost GLP-1s

STAT

The hormone leptin was discovered 30 years ago to much fanfare. Scientists hoped that leptin, which regulates body fat, could pave the way for obesity treatments. The results in mice were hailed as “miraculous,” and Amgen licensed the hormone for $20 million from Rockefeller University. But its initial promise failed to pan out, as treatments mimicking leptin in the body didn’t spur weight loss.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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From School to the Workforce, Burnout Plagues Every Level of Pharmacy

Pharmacy Times

Examining challenges in pharmacy school is necessary to solve current problems in the workforce.

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STAT+: U.K. to restrict Eli Lilly’s obesity drug to patients with greatest need 

STAT

LONDON — The U.K. will start offering Eli Lilly’s weight loss drug next year, but will restrict the medicine to people with the greatest need as the country tries to adapt to new ways of treating obesity amid surging demand.  Health authorities in the U.K. recommend tirzepatide, sold there as Mounjaro, for people with a body mass index of more than 35 and at least one related health condition.

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More Trending

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Conservative-led Supreme Court appears wary of weighing in on trans care bans

STAT

Conservative Supreme Court justices appeared skeptical Wednesday of arguments that they should intervene in Tennessee’s ban on gender-affirming care for minors.  The court heard arguments in U.S. v. Skrmetti that the state’s ban discriminated against transgender minors and denied them constitutionally equal protections. Outside the courthouse, in a sonic representation of the cultural divisiveness around the issue, advocates for gender-affirming care access blasted Bad Bunny a

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FDA signs off on Merus' first-in-class NRG1+ cancer drug Bizengri after brief delay

Fierce Pharma

Merus’ week keeps getting better. | The FDA had originally pushed its decision back by three months after a November manufacturing-related delay.

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STAT+: U.S. Patent Office pulls controversial rule to curb pharma patent abuse

STAT

In an unexpected move, the U.S. Patent & Trademark Office has withdrawn a controversial proposal that was designed to prevent pharmaceutical companies from abusing the patent system. Specifically, the proposed rule was crafted to stem the use of so-called patent thickets , which are wielded by drug companies to delay the arrival of lower-cost generic medicines in the marketplace.

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How automating flow cytometry is revolutionising cancer diagnosis and treatment

pharmaphorum

Discover how the automation of flow cytometry is transforming cancer diagnosis and treatment for breast, prostate, endometrial, pancreatic, kidney, and melanoma cancers. Explore the latest advancements in the field.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Why is health care cybersecurity so bad?

STAT

Year after year, more Americans are affected by health care data breaches. Though health savings accounts, pharmacies, and major hospitals have all been attacked in 2024, a single data breach accounted for the vast majority of people’s data being exposed: Change Healthcare. Multiple times this year, lawmakers have questioned health care industry experts about why the massive and disruptive Change Healthcare breach was allowed to happen , and what the government should do to improve health

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With AstraZeneca exec under investigation in China, company names Reic new international chief

Fierce Pharma

With AstraZeneca’s former international chief, Leon Wang, under investigation in China, the company has promoted an AZ veteran to fill the post. | With AstraZeneca’s former international chief, Leon Wang, under investigation in China, the company has promoted an AZ veteran to fill the post. The British giant has appointed Iskra Reic, Ph.D., as its new international executive vice president.

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CMS names two drug manufacturers for cell and gene therapy model

Fierce Healthcare

The Centers for Medicare & Medicaid Services has successfully negotiated agreements with two drug manufacturers to participate in the newly created Cell and Gene Therapy Access Model. | The two drugs treat sickle cell disease, the stated first priority of the new CMS model set to begin in January.

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With Makary set to face FDA commissioner hearings, how deep do his industry ties run?

PharmaVoice

Dr. Marty Makary’s conflicts of interest could come into question before he is confirmed as the next FDA commissioner.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Warning letter adds to Applied Tx run of bad news

pharmaphorum

Applied Therapeutics gets a warning letter from the FDA over a trial of rare disease drug govorestat, which was rejected by the agency last week

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Evaluating Pediatric Migraine Options Uncovers Challenges

Drug Topics

No medications were associated with improved quality of life or reduced headache duration.

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UK orders 5 million bird flu jabs for pandemic preparedness

pharmaphorum

The UKHSA has taken steps to prepare for a possible bird flu outbreak by placing an order with Seqirus for millions of H5 vaccine doses

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OTC Supplement Use Common For Symptom Management in Rheumatic Diseases

Drug Topics

Pain, fatigue, and sleep disturbances are common symptoms with rheumatic diseases.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Zepbound tops Wegovy in first head-to-head weight-loss trial

pharmaphorum

Eli Lilly's Zepbound beats Novo Nordisk's Wegovy in the first head-to-head trial comparing the two obesity drugs.

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Health Impacts for Patients Using Pre-, Pro-, Syn-, Postbiotics

Drug Topics

Researchers explored literature on the health benefits of the 4 main functional dietary components—prebiotics, probiotics, synbiotics, and postbiotics.

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The big rebrand: Why these 4 biopharmas changed their name this year

PharmaVoice

Four companies that refreshed their mission and public persona with a new look.

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Tirzepatide Bests Semaglutide in Relative, Average Weight Loss in Obesity, Overweight

Drug Topics

The drugs were compared over a 72-week study period.

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Social Determinants of Health Shape Outcomes in C difficile Infections

Pharmacy Times

Jacinda Abdul-Mutakabbir, PharmD, MPH, AAHIVP, discusses a study she conducted that highlights how social determinants of health exacerbate severity and increase rates of mortality from Clostridioides difficile infections in vulnerable communities.

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Post-Surgical Pain Treatment Gains FDA Breakthrough Therapy Designation

Drug Topics

ATX101 from Allay Therapeutics is designed for use following total knee arthroplasty in adults and has shown positive results in multiple studies.

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Are GLP-1 Receptor Agonists Eliminating the Need for Bariatric Surgery?

Pharmacy Times

Metabolic bariatric surgery rates has decreased in response to increased use of glucagon-like peptide-1 (GLP-1) receptor agonists.

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Vitamin D3 Supplementation Does Not Lower Risk of T2D in Healthy Older Adults

Drug Topics

A recent study found that, among older adults who are generally healthy and not at high risk for type 2 diabetes, Vitamin D3 supplementation does not significantly reduce the risk of developing the disease.

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Novo Nordisk keeps manufacturing expansion spree rolling with plans for $400M quality hub in Denmark

Fierce Pharma

Amid a multi-year, multibillion-dollar spending spree to scale its global manufacturing capacity, Novo Nordisk is laying down fresh foundations at its old stomping grounds in Denmark to bolster a c | Novo will invest 2.9 billion Danish kroner (roughly $409 million) to construct a new, 53,000-square-meter quality control laboratory in Hillerød, Denmark.

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AMA Urges Policymakers to Act Despite Report of Improved Opioid Epidemic

Drug Topics

AMA released its 2024 Overdose Epidemic Report and presented key findings from the past year.

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6 benefits of calendula tea

The Checkup by Singlecare

Calendula ( Calendula officinalis ) is a marigold plant related to daisies. It’s commonly referred to as pot marigold, and it’s native to Europe, Asia, and the Mediterranean region. Calendula flowers have been used for centuries as an herbal medicine. They’re known for having a variety of health benefits due to potent wound healing, antioxidant and anti-inflammatory properties.

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MHRA's stature undermined by lack of resources says pharma

pharmaphorum

The MHRA isn't sufficiently funded to meet its obligations and that could threaten UK investment in life sciences, according to an ABPI report

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Enhancing Patient Outcomes: The Role of Embedded Specialty Pharmacies in Biologic Access

Pharmacy Times

The study also found that HSSPs minimize health costs and provide additional revenue for health systems.

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STAT+: Pharmalittle: We’re reading about a Zepbound-Wegovy faceoff, compounders slamming Novo, and more

STAT

Greetings from STAT’s London outpost, with reporter Andrew Joseph here filling in for Ed. No particularly exciting flavored coffee to offer you today, but we did have a mulled cider last night that put us right into the festive spirit. Now, though, as ever, it’s back to the grind. Some tidbits below to help you start your day. … Eli Lilly said its weight loss drug Zepbound led to 47% greater weight reduction than rival medicine Wegovy, made by Novo Nordisk, in a head-to-head

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Brain-computer interfaces could redefine precision medicine

pharmaphorum

Brain-computer interfaces, such as Elon Musk's Neuralink, have the potential to revolutionise precision medicine and transform how we understand and treat the brain. Learn more about this groundbreaking technology and its implications in healthcare.

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