Mon.Sep 09, 2024

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Chronic Hand Eczema Studies Show Condition is Common, Burdensome

Drug Topics

LEO Pharma presented data from 2 of the largest multinational real-world studies on the prevalence, severity and treatment of chronic hand eczema at the European Society of Contact Dermatitis congress.

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Medicine struggles to define chronic Lyme. Long Covid has only made it harder

STAT

Going to the doctor is already tricky enough for people with chronic symptoms of Lyme disease. Their concerns often dismissed by mainstream medicine, those patients now face an additional hurdle: ruling out long Covid.  The two illnesses — one seeping in over the course of decades and another suddenly springing to life on a massive scale — share many qualities, including being widely misunderstood.

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Trending Sources

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The Future of Bispecific Antibodies in Aggressive B-Cell Lymphomas

Pharmacy Times

Presenter Krish Patel, MD, discusses the use of epcoritamab (Epkinly; AbbVie) and glofitamab (Columvi; Genentech) in aggressive B-cell lymphomas as monotherapies and in combination regimens.

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Biden administration finalizes rules to ensure insurers pay for mental health care 

STAT

The Biden administration on Monday announced it would finalize a highly anticipated proposal meant to force health insurers to cover mental health care on the same basis as physical health conditions.  It is the latest salvo in a long-running federal government effort to crack down on insurance plans skimping on treatment for conditions including anxiety, depression, and addiction.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Biden admin mandates mental health parity in final rule

Fierce Healthcare

The Biden administration is strengthening private health coverage for individuals seeking mental health and substance use disorder (SUD) care in a final rule unveiled Monday. | The feds are attempting to better regulate mental health coverage by bolstering protections around prior authorization, step therapy and provider networks.

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STAT+: With a win in lung cancer, biotech’s wealthiest outsider surfs to new heights

STAT

On Sunday, a small biotech company called Summit Therapeutics won a remarkable victory, saying its experimental drug outperformed Merck’s Keytruda , the world’s best-selling drug, in non-small cell lung cancer, the disease that represents Keytruda’s biggest market. By itself, Summit’s victory would be a dramatic story, although not an unheard of one in the unpredictable world of biotechnology.

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Opinion: How Pfizer ended up passing on my GLP-1 work back in the early ’90s

STAT

One of the biopharma industry’s marvels of the 2020s has been the enormous medical and financial success of the GLP-1 class of drugs. But the path to commercialization of these therapies was far more complex than most understand, and some of the earliest history has never been presented. Beginning in 1988, I was part of what I believe was the earliest commercial effort to develop GLP-1 as a metabolic therapy.

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AMA study: The 4 largest PBMs control 70% of the market nationally

Fierce Healthcare

The four largest pharmacy benefit managers in the U.S. | The four largest pharmacy benefit managers in the United States control 70% of the national market, according to new data from the American Medical Association.

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STAT+: House passes bill that targets China biotechs

STAT

WASHINGTON — The House Monday passed a bill by 306 to 81 votes to make drug companies stop doing business with some Chinese biotechs within eight years if they want to remain in good standing with the federal government. The BIOSECURE Act would prohibit the U.S. government from contracting with, or providing grants to, companies that do business with a “biotechnology company of concern.

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Rite Aid emerges from bankruptcy with $2.5B in exit financing and a new CEO at the helm

Fierce Healthcare

Retail pharmacy chain Rite Aid has emerged out of bankruptcy after slashing about $2 billion from its debt, the company announced last week. | Retail pharmacy chain Rite Aid has emerged out of bankruptcy after slashing about $2 billion from its debt, the company announced last week.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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A race-free algorithm is merely the start for a safety net hospital confronting an onslaught of kidney disease

STAT

NEW YORK — One Brooklyn Health, a safety net hospital system that serves some of this city’s poorest and sickest patients, would seem to be exactly the place to benefit most from the effort to remove race from calculations that assess kidney disease. The patients — mostly Black and insured by Medicaid or Medicare — are a case study in the disparities that run through American kidney care: A large number have advanced disease and require dialysis, but just a handful ge

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Texas sues HHS over rule that limits access to reproductive health information by law enforcement

Fierce Healthcare

The state of Texas is suing the Department of Health and Human Services in a Texas federal district court for a rule it finalized in April that gives healthcare organizations more discret | The state of Texas filed a lawsuit last week that argues a rule finalized by HHS' Office for Civil Rights is illegal. The Texas attorney general says HHS does not have statutory authority to keep information from law enforcement.

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How Paralympic athletes are helping science learn more about neuropathic pain

STAT

Elite athletes train and compete under a watchful eye. Fans and coaches track and measure every step, roll, or throw. But for athletes with a spinal cord injury, a key facet of their experience is unknown: neuropathic pain. Unlike musculoskeletal pain — say, from breaking your leg — neuropathic pain resides in the nervous system. And treating it is tricky: you can’t just pop an Advil or Tylenol and wait for the pain to subside.

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Tonix Pharmaceuticals Launches Campaign Promoting Non-Oral Medications for Gastroparesis, Migraine

Drug Topics

Whereby gastroparesis can hinder the absorption of oral medications in the stomach, Tonix Pharmaceuticals is promoting alternative migraine treatments that bypass the digestive system.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Apple pushes into sleep apnea detection but health care integration remains unclear

STAT

CUPERTINO, Calif. — Apple on Monday announced a new Apple Watch feature that will warn users they may have sleep apnea. It’s the latest advance in the company’s decade-long effort to sell its wearable as a tool that can help people live healthier lives. Additionally, the company announced more hearing health features for its wireless earbuds.

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Study Finds Annual Mammograms Associated With Lower Risk of Late-Stage Breast Cancer

Pharmacy Times

The study authors suggest that annual screening for women aged 40 and older may be beneficial, but warn of the increased risk of false positive results.

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STAT+: Merck executive plays down impact of new lung cancer drug data on Keytruda

STAT

With strong data released over the weekend, an experimental Chinese drug showed it could one day become an important therapy for lung cancer patients. But that doesn’t necessarily threaten the market dominance of Keytruda, a top Merck executive said — and some analysts agree. “I see these results as important, but preliminary,” Merck Chief Medical Officer Eliav Barr told STAT, reacting to the presentation Sunday of a Phase 3 clinical trial involving ivonescimab, a dru

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TROP2 Predictive of Clinical Outcomes in Patients With NCSLC Treated With Datopotamab Deruxtecan

Pharmacy Times

Datopotamab deruxtecan was effective in patients with TROP2-QCS biomarker-positive tumors for non–small cell lung cancer

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: RayzeBio, Dice alums raise $370 million for new autoimmune startup

STAT

After leading his previous company through a back-to-back IPO and M&A deal, the former chief executive of RayzeBio has raised $370 million to develop autoimmune therapies he believes could be “mega-blockbusters.” Those drugs are being developed by San Diego startup Candid Therapeutics, which launched Monday with financing from more than 20 investors.

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WCLC: Summit trumpets data with Keytruda challenger

pharmaphorum

Summit Therapeutics and Akeso's ivonescimab tops Merck's Keytruda in head-to-head phase 3 trial in first-line NSCLC, reported at WCLC.

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With TV drug ads, what you see is not necessarily what you get

STAT

Triumphant music plays as cancer patients go camping, do some gardening, and watch fireworks in  ads for Opdivo+Yervoy , a combination of immunotherapies to treat metastatic melanoma and lung cancer.  Ads for Skyrizi , a medicine to treat plaque psoriasis and other illnesses, show patients snorkeling and riding bikes — flashing their rash-free elbows.

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First Human Bird Flu Case Without Exposure to Infected Animal Discovered in Missouri

Drug Topics

The CDC confirmed another human bird flu case, marking the first instance of the virus in a human without occupational exposure to infected birds or dairy cattle during the 2024 outbreak.

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Opinion: Breakthrough therapies have given Duchenne muscular dystrophy families like mine hope — and new fears

STAT

Duchenne muscular dystrophy has seen more progress in the past 15 months (give or take) than in the last couple of decades combined. In that time, the Food and Drug Administration has approved three new therapies: Elevidys (delandistrogene moxeparvovec-rokl), the first micro-dystrophin gene therapy; Duvyzat (givinostat), a non-steroidal HDAC inhibitor; and Agamree (vamorolone), a new corticosteroid.

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How Pharmacy Advocacy is Heating Up at the Federal Level

Drug Topics

Drug Topics discussed independent pharmacy advocacy and PBM reform on the federal level with Miguel Rodriguez, Executive Vice President and general counsel for American Pharmacies.

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STAT+: Relay discloses encouraging results for experimental breast cancer treatment

STAT

Relay Therapeutics disclosed encouraging results for its key breast cancer drug and plans to advance the experimental treatment, called RLY-2608, to a late-stage clinical trial, the biotech firm said on Monday. The new data come from an open label phase 1/2 trial on RLY-2608 combined with fulvestrant, an endocrine therapy for breast cancer, showing a third of patients with measurable disease responded to the treatment.

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Digital Solution Implementation

Pharmaceutical Commerce

In the second part of her interview with Pharma Commerce Editor Nicholas Saraceno, Meghan Mullooly, Archbow Consulting’s Vice President, offers advice to pharma manufacturers for successfully applying digital solutions to their patient support programs.

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STAT+: Highmark reboots coverage of digital treatments, raising hope among DTx companies

STAT

Highmark Health, a large regional health insurer that also owns a chain of hospitals, is now covering a handful of digital treatments for chronic pain and other conditions for millions of its patients. The move, which could provide a boost to digital therapeutics makers, may feel like déjà vu for close industry observers.  In 2022, Pittsburgh-based Highmark issued a policy stating that it would cover eight Food and Drug Administration-cleared prescription digital therapeutics for

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How Chiesi is walking the walk on pharma sustainability

pharmaphorum

Discover how Chiesi is leading the way in pharmaceutical sustainability by partnering with EcoVadis and implementing innovative practices. Learn how they are making a positive impact on the environment and society.

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Terns’ GLP-1 pill leads to weight loss in early study

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Lots of bispecific talk on this delightful September day, as well as discussion around new concerns in Duchenne treatment as more options become available.

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Impact of Value-Based Care in Oncology: Insights from COA 2024

Pharmacy Times

Lalan Wilfong, MD discusses the road to value-based care and payment reform in cancer care.

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How long does NyQuil last?

The Checkup by Singlecare

When you’re dealing with a nasty virus, one of the most popular over-the-counter medication options is Vicks NyQuil. NyQuil can treat a variety of cold symptoms, such as sore throat, runny nose, coughing, sneezing, and flu symptoms like body aches or fever. Another bonus is that NyQuil can cause drowsiness, which can help you more easily sleep throughout the night rather than tossing and turning until the wee hours.

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Driving economic growth in UK with commercial clinical trials

European Pharmaceutical Review

A report from Frontier Economics has highlighted the major benefit industry clinical trials have had on UK’s economy. For instance, it has supported its growth and the job market, the research showed. Of the 65,000 jobs generated, 21,000 individuals were employed directly by the pharmaceutical industry to deliver trials, according to the data. While industry clinical trials in the UK have reduced , the Association of the British Pharmaceutical Industry (ABPI) stated that if the activity assumes

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Lilly lays down $1B to be ‘first in biology’ with obesity gene therapies

PharmaVoice

The deal, which targets metabolic diseases, is one of a few by Big Pharma to develop lncRNA therapies.

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