Wed.Nov 06, 2024

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STAT+: AstraZeneca says China has detained a senior executive

STAT

The executive in charge of AstraZeneca operations in China is under detention by Chinese authorities who are investigating employees there, the company said. The disclosure comes after AstraZeneca last week acknowledged that Leon Wang, an executive vice president who also oversees international operations for the drugmaker, was being investigated along with a “small number” of employees.

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Opioid Stewardship Pharmacist: Innovative Approaches to Pain Management

Pharmacy Times

Jeff Boyer, PharmD, BCPS, discusses his role in opioid stewardship at the Southern Arizona VA Healthcare System, highlighting his work in pain management coordination, interdisciplinary collaboration, patient and provider education, and data-driven strategies to support safe opioid use and address the opioid crisis.

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Novavax coughs up $123.8M to settle COVID vaccine supply dispute with UK

Fierce Pharma

Novavax has inked another settlement for a past COVID-19 vaccine supply deal. | Novavax has inked another settlement for a past COVID-19 vaccine supply deal. The Maryland biotech has agreed to pay $123.8 million to end a COVID vaccine supply pact with the U.K.

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Women Within Health Care Face Financial Disparities and Are More Likely to Experience Burnout

Pharmacy Times

The authors believe that improvements can be made to overlook the motherhood penalty and its associated pay gaps as well as changes to address workforce burnout.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Unlock the Benefits of Centralized Fulfillment for Pharmacists: A Comprehensive Guide

Drug Topics

Streamline your pharmacy operations with centralized fulfillment. Discover how automation and advanced software can improve patient care, reduce operational errors, and create a better work environment for pharmacists. Download our whitepaper to learn how centralized fulfillment can address rising prescription volumes and staffing shortages. Request a consultation today to explore the best solution for your pharmacy.

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ENVISION Trial Results Show UGN-102 Has Long-Term Durability in Patients With Bladder Cancer

Pharmacy Times

Patients with low-grade intermediate-risk non-muscle-invasive bladder cancer who achieved a complete response rate after 3 months of UGN-102 treatment had an 82.3% duration of response at 12 months.

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More Trending

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Cognitive Remediation, Transcranial Direct Current Stimulation Slow Cognitive Decline in At-Risk Older Adults

Pharmacy Times

For up to 6 years, cognitive remediation and transcranial direct current stimulation slowed cognitive decline associated with major depressive disorder in remission and mild cognitive impairment.

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XRHealth buys NeuroReality in health XR marriage

pharmaphorum

Two players in medical extended reality (XR) – XRHealth and NeuroReality – have come together in a quest to build the biggest company in the sector.Boston, US-based XRHealth is leading the deal, acquiring NeuroReality of the Netherlands for an undisclosed sum, combining their products and expertise in the use of XR and virtual reality software for healthcare applications.

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RSV Preventative Monoclonal Antibody Could Reduce Disease Incidence in Preterm, Full-term Infants

Pharmacy Times

Clesrovimab reduced RSV-associated hospitalizations and RSV-associated lower respiratory infection hospitalizations by more than 84% and 90% in preterm and full-term infants, respectively.

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Opinion: Pharma’s ethically questionable sites essentially sell drugs directly to consumers

STAT

Want to self-prescribe a prescription drug? No problem! Some of the largest pharmaceutical companies in the U.S. are piloting websites that essentially sell their drugs directly to consumers. This unprecedented move launches a new dystopic era: pharmaceutical companies as health care provider, no pesky physician middlemen needed. It’s what the pharmaceutical industry has always wanted: They have long viewed physicians as inconvenient barriers between the company and their customers.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Bone Marrow Adipocytes May Offer Early Detection of MGUS Progression to Multiple Myeloma

Pharmacy Times

Increased bone marrow adiposity is associated with progression of monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma.

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Psychedelics decriminalization rejected by Massachusetts voters

STAT

Massachusetts voters on Tuesday rejected Question 4, the ballot measure that proposed decriminalizing the use of psychedelic substances for people older than 21 and allowing people to grow the hallucinogens at home. The AP projected the result in the early morning hours of Wednesday. The initiative proposed to decriminalize the use of five psychedelic compounds, most notably  psilocybin , or so-called magic mushrooms, which can dramatically affect a person’s perceptions and thinking.

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NCPA 2024 Meeting Recap

Drug Topics

Checkout some of the most important sessions and video interviews from the 2024 National Community Pharmacists Association (NCPA) Annual Convention and Expo.

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STAT+: Novo’s earnings report sends shares up, as obesity drug sales show continued growth

STAT

LONDON — Sales of Novo Nordisk’s obesity drug Wegovy jumped in the third quarter, the company said Wednesday as it reported quarterly profits that were in line with analyst expectations. Novo’s third quarter performance will be seen as a win for the company, particularly after Eli Lilly — its rival in the booming obesity drug market — reported earnings last week that fell below forecasts.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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While the Orphan Battles Wages, Jazz Takes a Loss

The FDA Law Blog

By Sara W. Koblitz — The fight between Jazz, Avadel, and FDA over narcolepsy drug sodium oxybate has been a long and arduous one. Starting in 2022 with a patent certification requirement, both Jazz and Avadel have sued FDA over this drug, with Jazz most recently bringing suit challenging FDA’s decision that Avadel’s Lumryz (sodium oxybate) is clinically superior to Jazz’s Xywav (sodium oxybate) in 2023.

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First-of-a-kind EU approval granted for eosinophilic esophagitis medicine

European Pharmaceutical Review

Dupixent (dupilumab) has been approved by the European Medicines Agency (EMA) as the first treatment for young children with eosinophilic esophagitis in the EU. This authorisation is based on Phase III data which found that 68 percent of children aged one to 11 years given Dupixent (dupilumab) achieved histological disease remission at 16 weeks. This result was maintained for up to one year.

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Top 20 biopharmas’ market cap rises 2% in Q3 2024 amid flurry of drug approvals

Pharmaceutical Technology

The top 20 biopharmaceutical companies demonstrated signs of recovery during the third quarter (Q3) of 2024 as investor optimism improved following the interest rate cuts by the US Federal Reserve in September 2024.

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'Treat These Patients With Compassion': Expert Discusses Pharmacists' Role in Counseling Benzodiazepine Use

Pharmacy Times

Brian Anderson, PharmD, RPh provides important considerations for pharmacists regarding patient use of benzodiazepines.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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CVS taps former UnitedHealthcare CEO Steve Nelson to lead Aetna

Fierce Healthcare

CVS Health announced two key leadership appointments as it continues the push to improve its financial performance. | CVS Health announced two key leadership appointments as it continues the push to improve its financial performance.

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STAT+: Pharmalittle: We’re reading about compounded Wegovy, pharmacies suing GoodRx, and more

STAT

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. Regardless of elections, we generally see the proverbial glass as half full. For those of you who worry the sky is falling, we will pass along something learned on Wall Street: “Sell sky.” After all, we have made it this far, so we are determined to hang on for another couple of days.

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Drug Shortages More Likely in US Than in Canada

Drug Topics

Researchers compared the issue of drug shortages and supply chain challenges between the US and Canada.

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Wegovy romps ahead after key rival sees slowdown

pharmaphorum

Novo Nordisk's sales of blockbuster obesity drug Wegovy grew by a massive 79% in the third quarter, in a relief to investors after disappointing results three months ago.

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Opinion: How your genetics could determine your politics

STAT

No matter who wins the 2024 presidential race, one thing is clear: Political anxiety and division will remain high for the foreseeable future. So just before Election Day, I spoke with Kevin Smith, a professor of political science at the University of Nebraska who studies the intersection of political attitudes, biology, and evolution.  In 2019, he and colleagues published a study that found almost 40% of Americans reported experiencing stress over politics, 11.5% thought their physical hea

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Why Vaccination Uptake is Crucial During the Winter Season

Drug Topics

Ruth Carrico, PhD, DNP, APRN, sat down with Drug Topics to discuss the importance of COVID-19 and influenza vaccination.

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AstraZeneca falls on reports of Chinese probe

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning, major news this morning, so let’s get straight to it.

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US Supreme Court reviews case impacting billions in Medicare DSH payments for hospitals

Fierce Healthcare

The U.S. Supreme Court heard oral arguments Monday in a case centered on Congress’ formula for calculating disproportionate share hospital payments. | The U.S. Supreme Court heard oral arguments Monday in a case centered on Congress’ formula for calculating disproportionate share hospital payments.

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Company Profile: HCG

pharmaphorum

HCG’s drive to transform is motivated by industry-leading perspective on the emerging trend of “impact”, and recognition that understanding that the impact of medical communications efforts is more critical than ever.

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Drugs for unmet needs and those from experienced companies had the best chance for successful launches in 2023: report

Fierce Pharma

Drugs for unmet needs and those from experienced companies had the best chance for successful launches in 2023: report kdunleavy Wed, 11/06/2024 - 09:23

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Alligator pancreatic cancer drug 'nearly doubles' survival

pharmaphorum

New results with Alligator's CD40 agonist mitazalimab show it nearly doubled survival in pancreatic cancer, ahead of phase 3 trial next year.

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Insulin Icodec Represents A Promising Option for Managing Diabetes, Improving Quality of Life

Drug Topics

Jennifer Goldman, PharmD, CDCES, BC-ADM, FCCP, discusses how insulin icodec differs from existing daily basal insulins and key things pharmacists need to know about the medication.

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Streamlining eCOA: From complex setup to simplified solutions

Outsourcing Pharma

As clinical trials evolve, electronic Clinical Outcome Assessments (eCOA) remain central to data quality but often lag in adoption due to complex setup and deployment challenges.

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After Lilly's GLP-1 sales fumble, Novo reports mixed results on Ozempic, Wegovy

Fierce Pharma

Following a disappointing earnings showing from Eli Lilly last week, Novo Nordisk’s latest report on the performance of its GLP-1 stalwarts Ozempic and Wegovy is more of a mixed bag. | Among Novo’s semaglutide-based drugs, diabetes blockbuster Ozempic fell short of analysts' expectations during the third quarter while weight-loss med Wegovy came above a consensus estimate.

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Cigarette Smoke Hinders Innate Immune Response to Pneumococcal infection

Pharmacy Times

Known to be a leading cause of mortality worldwide, cigarette smoke exposure can make the respiratory tract more susceptible to pneumococcal infection.