Fri.Mar 15, 2024

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Blood-Based Test Demonstrates High Sensitivity for Colorectal Cancer

Drug Topics

A blood-based cell-free DNA (cfDNA) test was able to find patients at increased risk of colorectal cancer (CRC), advanced neoplasia, and advanced precancerous lesions.

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With Pfizer struggling in 2023, CEO Bourla hit with 35% pay cut to $21.6M

Fierce Pharma

Pfizer knew 2023 was going to be a challenging year of transition. But even the drugmaker was surprised by the plummeting demand for its COVID-19 products, missing badly on its 2023 guidance. | After a difficult year for Pfizer, in which its share price fell by 44%, CEO Albert Bourla’s compensation fell by 35% from $33 million in 2022 to $21.6 million in 2023.

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Trending Sources

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What the brains of song birds can teach us about human stuttering

STAT

A symphony of synapses fires every time a songbird sings. For Erich Jarvis, a neurobiologist at Rockefeller University, the neural pathways he finds particularly interesting inside a birds’ brain are those that enable the bird to make new sounds from listening to their environment. This is an ability known as vocal learning, and is perhaps most notably exhibited when a parrot mimics a person’s speech (or profanity).

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HIMSS24: Oracle Health builds out generative AI tools in its quest to 'eliminate clicks' for clinicians

Fierce Healthcare

ORLANDO, Florida — Software giant Oracle continues to build out generative AI tools in its healthcare solutions as it debuted a new service for care management this week and plans to roll out | Oracle is integrating generative AI and ambient listening technologies into its EHR to streamline medical notetaking for clinicians. "We're not trying to go from 10 clicks to seven clicks.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: FDA advisers back CAR-T therapies in blood cancer, despite safety concerns

STAT

A panel of expert advisers to the Food and Drug Administration on Friday voted in favor of expanding the use of CAR-T therapy in blood cancer, despite concerns about the powerful treatment’s side effects. The group voted 11-0 that the benefits of Carvykti, a CAR-T medicine from Johnson & Johnson and Legend Biotech, outweighed its risk for patients with multiple myeloma whose disease has persisted despite initial treatment.

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AHA: 94% of hospitals financially impacted by Change Healthcare's cyberattack

Fierce Healthcare

Nearly every hospital is feeling the consequences of Change Healthcare’s cyberattack on their finances, patient care delivery, or both, according to reports from almost 1,000 hospitals compiled by | Almost 60% of surveyed hospitals reported at least $1 million of impacted revenues per day, and 74% said that the incident has had "direct" implications on patient care within their facilities.

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MedPAC report slammed by insurers and docs over Medicare Advantage and physician reimbursement

Fierce Healthcare

Health plans and providers alike are disgruntled with a new report (PDF) to Congress released | It seems everyone was left unsatisfied by MedPAC's newest report to Congress. Providers objected to its proposal to give physician reimbursement relief, while plans disagreed with its attitude toward Medicare Advantage.

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LSD D-Tartrate Receives Breakthrough Therapy Designation From FDA for Generalized Anxiety Disorder

Pharmacy Times

LSD d-tartrate (MM-120) showed rapid improvements in patients with generalized anxiety disorder by day 2 of the study.

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Despite early death concerns, FDA advisers back J&J and Legend's Carvykti for earlier myeloma

Fierce Pharma

Even though the BCMA CAR-T therapy Carvykti showed a potential problem of early patient deaths in a trial, experts on the FDA’s Oncologic Drugs Advisory Committee (ODAC) still believe that the drug | Even though the BCMA CAR-T therapy Carvykti showed a potential problem of early patient deaths in a trial, experts on the FDA’s Oncologic Drugs Advisory Committee still believe that the drug’s long-term benefits outweigh its risks.

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Study: Only 40% of Adults With Childhood Asthma Experience Remission

Pharmacy Times

The study showed no clinical differences for remission or asthma at age 28 years based on lung function, body mass index, daily smoking, exposure to parental tobacco smoke, or house dampness.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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KFF: A look at healthcare spending trends in Medicare households

Fierce Healthcare

Medicare households are spending far more on healthcare than other households, according to a new KFF analysis. | Medicare households are spending far more on healthcare than other households, according to a new KFF analysis.

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Novartis lays out $256M for antibody plant expansion in Singapore, plots 100 hires

Fierce Pharma

Over the years, Singapore has attracted a suite of biopharma majors, and Novartis is no exception. | Novartis broke ground on a $256 million expansion of its biopharmaceutical production facility in Singapore. The project will introduce digitalization and automation at the site in a bid to boost manufacturing productivity and to help upskill the company’s workforce.

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Practice Better adds new tools, billing integration for mental health practitioners

Fierce Healthcare

Practice Better, a practice management software vendor, is expanding its platform to better support the needs of mental health practitioners. | The practice management platform is adding range of mental health screening forms, client progress tracking tools and mental health templates with more specialized features to its platform. It has also teamed up with clearinghouse Claim.MD to add insurance billing integration to its platform.

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STAT+: Bayer exec: U.S. is key in reviving beleaguered pharma’s drug pipeline

STAT

German pharmaceutical company Bayer is expanding its U.S. pharma business significantly, despite corporate turmoil and pricing pressures that have led many in the drug industry to bemoan the potential end of the American biotech innovation boom. Bayer’s C-suite has been on a soul-searching mission for the last year, spurred by new leadership and the realization that the company is, as new CEO Bill Anderson said earlier this month, “ badly broken.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Senate Finance Committee grills Becerra on HHS' delayed relief in Change Healthcare cyberattack

Fierce Healthcare

Leading senators want Department of Health and Human Services, insurers and hospitals alike to know they’re keeping a close eye on the fallout from Change Healthcare’s cyberattack. | Influential senators held HHS Secretary Xavier Becerra's feet to the fire on Thursday, urging him and his department to deliver prompt support and maintain pressure on the industry to invest in cybersecurity.

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Navigating digital transformation in pharma: The rise of mobile messaging

pharmaphorum

Popular mobile messaging apps that offer end-to-end encryption for their users' communications means that the content of messages is only accessible to the sender and the recipient. However, like any software, they still have potential cybersecurity risks and compliance concerns that users should be aware of - especially in pharma.

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Terlipressin Has Been Shown to Improve HRS Reversal Outcomes, but Concerns Remain

Pharmacy Times

The drug is the first FDA-approved agent for treating hepatorenal syndrome.

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After Amylyx drug failure, what’s next for ALS?

PharmaVoice

The company’s combo treatment Relyvrio was approved in 2022, but after failing a phase 3 trial, may be pulled from the market.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Community Health Workers Can Promote Diversity in Clinical Trial Enrollment

Pharmacy Times

Their expansive scope of services can ultimately help to elevate the work of the entire community pharmacy.

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Changing Faces: Digital and supplier hires from February 2024

pharmaphorum

Explore the latest digital and supplier hires in the pharmaceutical industry, including Campbell, EMS Healthcare, PhRMA, and Exscientia in February 2024. Stay updated on the changing faces in industry.

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FDA Grants Breakthrough Device Designation for Neuroimmune Modulation Platform To Treat MS

Pharmacy Times

The platform is a first-of-its-kind therapeutic approach to promote remyelination among individuals with relapsing/remitting multiple sclerosis.

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Future medicine makers will get VR training at new UK centre

pharmaphorum

Consortium led by Birmingham University unveils a centre of excellence for medicines manufacturing training using VR, to answer a UK skills shortage.

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What happens when an approved drug doesn’t work?

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hey there. Today, we see the first approval of a drug to treat MASH, a Gilead medication shows huge promise in Ebola, and more.

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ALS body takes digital approach to clinical trials access

pharmaphorum

The ALS Association is partnering with myTomorrows to connect patients and physicians with clinical trials using a digital platform.

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Risankizumab Significantly Reduces Severity of Psoriasis Symptoms

Pharmacy Times

Compared to placebo, risankizumab significantly reduced symptom severity for patients with moderate to severe disease.

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8 Ways to Cope with a Disappointing Residency Match 

Board Vitals - Pharmacist

You’ve worked tirelessly through years of medical school, and the culmination of your efforts has finally arrived: the residency match. While you may be excited to have matched, it can be disappointing to realize you matched into a program lower on your preference list, especially as watch your classmates celebrate their own successes. It’s okay to feel disappointed, and it’s natural to have envisioned a different outcome after investing so much time and effort into your medica

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With FDA greenlight, BMS Breyanzi brings CAR-T cell therapy to CLL and SLL

Pharmaceutical Technology

Amidst the many BTK inhibitors, Breyanzi will be the first and only CAR-T cell therapy available for the treatment of CLL and SLL.

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The Case for Domestic Sourcing to Establish Reliable Pharmaceutical Supply Chains in the United States

Pharmaceutical Commerce

Reliance on foreign imports means that disruptions in the supply chain can profoundly impact the ability of individuals in the United States to get access to the medications they need.

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FDA approves first treatment for liver scarring due to fatty liver disease

Pharmafile

The US Food and Drug Administration (FDA) has announced that it has approved Rezdiffra (resmetirom) for the treatment of adult patients with noncirrhotic non-alcoholic steatohepatitis (NASH) with moderate to advanced liver scarring (fibrosis), for use alongside diet and exercise. This approval follows an analysis of the safety and efficacy of the drug based on a […] The post FDA approves first treatment for liver scarring due to fatty liver disease appeared first on Pharmafile.

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Madrigal Pharma is first over the MASH finish line

pharmaphorum

Madrigal Pharma is first pharma company to get FDA approval for a drug to treat metabolic dysfunction-associated steatohepatitis (MASH)

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Pharma Pulse 3/15/24: Elranatamab Maintains or Improves Symptoms of Multiple Myeloma Patients, AI Assistant for Security Products & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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Healthee heads latest crop of digital health financings

pharmaphorum

Our latest round-up of funding rounds in the digital health category features updates from Healthee, Aktiia, Moxe Health, Eleanor Health, Tava Health, BrainCheck, and Redi Health.

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Getting the Lay of the Land After a Banner Year for Biosimilars

Pharmaceutical Commerce

Biosimilars market experiences massive growth, but regulatory and adoption challenges remain.

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