Wed.Oct 09, 2024

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The Perils of Frivolous Lawsuits

Drug Topics

Current rules governing lawsuits must be revisited to strike a balance between legitimate and frivolous legal actions against health care providers.

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STAT+: 7 children developed blood cancer after Bluebird Bio gene therapy for rare neurological disease

STAT

Newly published data show that seven out of 67 children who received Bluebird Bio’s gene therapy for a devastating neurological disorder in clinical trials have since gone on to develop blood cancers.  That means four additional patients have developed blood cancers since June 2022, when concerns about three cancer cases prompted the Food and Drug Administration to hold a hearing of outside advisers before approving the treatment, marketed as Skysona.

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Texas Sues Multiple PBMs, Drug Manufacturers Over Inflated Insulin Prices

Drug Topics

On October 3,2024, Texas Attorney General Ken Paxton issued the lawsuit, which involves Eli Lilly, Express Scripts, CVS Pharmacy, and other pharmaceutical entities.

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STAT+: As U.S. efforts stall, China pushes ahead with CRISPR treatments for muscular dystrophy

STAT

Two of the first efforts to treat Duchenne muscular dystrophy with CRISPR gene editing are getting off the ground in China, even as projects in the U.S. have seemingly stalled. Trials for the fatal muscle-wasting disease were started in the last couple of months by two different Chinese companies. One, GenAssist, has already dosed one young boy. Huidagene, the other biotech, expects to dose the first of three boys soon and report data by Q1 next year.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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5 Questions With a Pharmacist: Anthony Minniti from Bell Pharmacy

Drug Topics

In an installment of Drug Topics’ 5 Questions With a Pharmacist, Anthony Minniti of Bell Pharmacy in Camden, New Jersey, discussed pharmacy in his community and the challenges that come with it.

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2024 Nobel Prize in chemistry: Three scientists win for groundbreaking work in proteins

STAT

LONDON — A trio of scientists who opened new doors in our understanding of the structure of proteins — the fundamental building blocks of biology — and even came up with ways to create new proteins won the Nobel Prize in chemistry Wednesday. The prize went to David Baker of the University of Washington, and to Demis Hassabis and John Jumper, who work at Google DeepMind in London.

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How hospitals are grappling with the IV fluid shortage wrought by Hurricane Helene

STAT

Hospitals across the country are struggling to conserve and stretch their supplies of IV fluids in the wake of a shortage brought on by Hurricane Helene, in some cases giving patients Gatorade instead of IVs and warning the issue could lead to delays in elective medical procedures in the near future. A Baxter facility in North Carolina that produces more than half the nation’s IV solutions was forced to close after Helene, while Hurricane Milton is now bearing down on Florida, where a pla

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Disruptive cyberattacks against healthcare on the rise, with increasing impacts to patient care, survey finds

Fierce Healthcare

Reports of recent cyberattacks and disruptions in patient care have ticked up among healthcare organizations since 2023, with the average attack bringing just under $1.5 million in operational disr | Ninety-two percent of polled healthcare IT and security practitioners said their organization had faced at least once cyberattack during the prior year.

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STAT+: Medicare already covers GLP-1s for half of seniors with obesity, new report finds

STAT

WASHINGTON — A new report from congressional budget experts this week estimated that it would cost Medicare an additional $35 billion over nine years if the program began covering GLP-1 drugs for obesity. But the report also noted that half of seniors who would qualify for obesity coverage already have access to the drugs for other conditions.

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Fulfilling My Purpose as a Future Bilingual Pharmacist – Honoring Hispanic Heritage in Pharmacy

Pharmacy Is Right For Me

Hello everyone, my name is Diana Martinez-Nava and I am a fourth-year student pharmacist at The University of New Mexico College of Pharmacy. I would like to take some time on this special month celebrating our Hispanic Heritage to share my story on my pharmacy journey. My interest in becoming a pharmacist began around the time I was 8 years old. I was that small child who could barely see over the counter at our neighborhood pharmacy next to my father’s arm who would be reaching out to collect,

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Q&A: How the FDA is approaching AI in clinical trials and drug development

STAT

In the last year, pharma incumbents have leaned into partnerships with AI-driven startups to supercharge drug discovery efforts. High-powered models of protein structure and molecule binding can help identify new disease targets, and even help design new drugs. But AI-derived or not, a new drug candidate still has to wind its way through the painstaking clinical trial process.

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CMS rolls out proposed generic drug list to ease cost-sharing burden

Fierce Healthcare

The Centers for Medicare & Medicaid Services (CMS) released a list of prescription drugs it hopes to include in its new Medicare $2 Drug List Model, the agency announced Wednesday. | CMS is looking to further refine its new Medicare $2 Drug List Model to make prices more predictable for Part D beneficiaries.

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STAT+: GSK to pay $2.2 billion to settle most Zantac lawsuits over claims the heartburn pill causes cancer

STAT

After protracted legal battling, GSK has agreed to pay $2.2 billion to settle most of the pending lawsuits that claimed a discontinued version of the Zantac heartburn medication caused cancer. The settlement covers roughly 80,000 cases, or 93% of the suits that were outstanding in state courts around the U.S. At the same time, the company agreed to pay $70 million to settle a whistleblower lawsuit that was filed by Valisure, an independent laboratory that alleged GSK concealed the link between t

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Advancing Precision Care For All

pharmaphorum

Advancing Precision Care For All with Hakim Yadi from Closed Loop Medicine. Listen to the latest podcast episode featuring insights from a leader in the healthcare industry.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Eli Lilly, Insitro ink a new kind of AI drug development deal

STAT

Machine-learning drug development company Insitro has inked three agreements with Eli Lilly for new medicines for metabolic diseases. But the deal is a little different compared to many recent deals between burgeoning artificial intelligence upstarts and established pharma giants: After identifying drug candidates, Insitro will be responsible for commercializing the drugs, and Lilly will be eligible for milestones and royalties.

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Dual-Role SARS-CoV-2 Antibody Discovered, Both Assisting and Blocking Virus Depending on Variant

Pharmacy Times

The discovery marks the first time an antibody has been observed to both assist and block viral infection with SARS-CoV-2.

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Assessing the Efficacy of Mepolizumab in Asthma, COPD

Drug Topics

Research Presented at CHEST 2024 reported on how mepolizumab can improve asthma control, and reduce exacerbations of concurrent asthma and COPD.

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Ciltacabtagene Autoleucel Demonstrates Promising Efficacy, Safety in Real-World Study

Pharmacy Times

The real-world study results of ciltacabtagene autoleucel are comparable to data from the CARTITUDE-1 trial, emphasizing its efficacy and safety.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Amazon plots big expansion of pharmacy business to offer same-day delivery to 20 new cities in 2025

Fierce Healthcare

Amazon plans an aggressive expansion of its pharmacy business to offer same-day delivery of prescription medications to 20 new cities in 2025, which more than doubles its current operations. | Amazon plans an aggressive expansion of its pharmacy business to offer same-day delivery of prescription medications to 20 new cities in 2025, which more than doubles its current operations.

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Study Finds High Dose Vitamin D3 Does Not Benefit Survival for Metastatic Colorectal Cancer

Pharmacy Times

The addition of high-dose vitamin D3 to standard treatment did not delay the progression of cancer compared with the standard dose of vitamin D3.

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‘It’s been hard to watch.’ A noted epidemiologist talks H5N1 and the U.S.’s fragmented response

PharmaVoice

Katelyn Jetelina, well known for her newsletter “Your Local Epidemiologist,” digs into the H5N1 outbreak, the public health response and what’s next for vaccinations.

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Pharmacists Serve as a “Golden Ticket” For Patients

Pharmacy Times

Two MUSC pharmacists describe how pharmacists are often the educational resource for patients and can help when removing certain barriers to care.

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Importance of choosing the right POC marketing partners in healthcare

pharmaphorum

Choosing the right POC (point of care) marketing partners in healthcare is crucial for reaching healthcare professionals (HCP) effectively. Learn about the importance and benefits of selecting the right partners in this essential marketing strategy.

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Biogen fills in some of the blanks on its trial of a high-dose version of Spinraza

Fierce Pharma

A trial of Biogen’s spinal muscular atrophy therapy Spinraza suggests that a higher dose provides benefits to a broad range of patients.

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Prime Medicine lays off workers as it trims pipeline

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning to everyone except the Empire State Building.

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Pfizer CEO Bourla to meet with activist investor Starboard Value on turnaround pitch: FT

Fierce Pharma

With Pfizer’s revenue and share price slumping after the drugmaker skyrocketed to new heights during the pandemic, the company’s executives will reportedly hear out activist investor Starboard Valu | Activist investor Starboard Value recently picked up a $1 billion stake in the drugmaker and will now pitch a strategy shift to top executives, the Financial Times reported.

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The future of multiple myeloma is personalised, but we must work together to deliver it

pharmaphorum

The future of multiple myeloma treatment is personalised, but collaboration is essential to deliver it. Learn about the latest advancements and how working together can improve outcomes for patients.

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Big 3 PBMs want Lina Khan off the FTC insulin lawsuit

Fierce Healthcare

UnitedHealth Group, CVS Health and Cigna all submitted motions Oct. 8 to remove Lina Khan from the Federal Trade Commission’s ongoing antitrust lawsuit. | UnitedHealth, CVS Health and Cigna all view FTC chair Lina Khan as unfair toward PBMs and say she should be removed from the FTC's recently filed antitrust lawsuit.

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Do HCPs really want the return of in-person meetings?

pharmaphorum

Discover if healthcare professionals prefer the return of in-person meetings or are embracing virtual alternatives instead. Explore the benefits and challenges of virtual events for HCPs.

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STAT+: Epic Systems v. Particle: What the Carequality investigation reveals about the dispute

STAT

Late Tuesday night, Carequality released new information about its investigation into the dispute between electronic health records vendor Epic Systems and health data startup Particle Health that has now escalated into an antitrust lawsuit. The dispute between the two started earlier in the year when Epic accused Particle of requesting and sharing health data with customers in violation of Carequality’s rules.

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Examining the Impact of COVID-19 on Patients with Liver Disease

Drug Topics

Research presented at CHEST 2024 examined outcomes of COVID-19 on patients with alcoholic liver disease, cirrhosis, and non-alcohol steatohepatitis.

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GSK says $2.2bn settlement resolves most Zantac litigation

pharmaphorum

GSK says a $2.

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Exploring Challenges in Diagnosis, Treatment of Asthma-COPD Overlap Syndrome | CHEST 2024

Drug Topics

Two posters presented at the annual meeting of the American College of Chest Physicians, CHEST 2024, offered insights into the accurate diagnosis and appropriate treatment of ACOS.

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