Sat.Dec 09, 2023

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Prenatal Folate May Program Hematopoietic Stem Cell Function Into Adulthood

Pharmacy Times

The study findings have implications for the identification of novel pathways with which to selectively target folate-metabolism blood cancers.

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STAT+: CAR-T, recently used in a lupus patient, helps other autoimmune patients, too, in small study

STAT

SAN DIEGO — When the first lupus patient received CAR-T therapy, researchers watched in amazement as her autoimmune disease rapidly went into remission. Then, they monitored her disease anxiously for months, wondering if it would return — especially as her immune B cells began recovering. Now, two and a half years later, the researchers reported at the annual American Society of Hematology meeting that not only is this patient still in complete remission without the use of any

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As FDA puts CAR-T safety under microscope, researchers dig into adverse events record of BCMA therapies

Fierce Pharma

BCMA-targeted therapies are transforming care for multiple myeloma patients. But these immunotherapies also come with various potentially dangerous side effects. | A new study examined side effect reports of BMCA immunotherapies from the FDA Adverse Event Reporting System, hoping to help inform doctors in their treatment decisions.

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STAT+: Historic approval of sickle cell gene therapies met with cautious optimism by experts at ASH

STAT

SAN DIEGO — News of the Food and Drug Administration’s historic approval of the first gene therapies for sickle cell disease sparked discussion, debate, and, above all, measured optimism at this year’s meeting of the American Society of Hematology. Doctors and researchers noted that the approval of both therapies, one made by Vertex Pharmaceuticals and CRISPR Therapeutics and the other by Bluebird Bio, marked a landmark shift in the treatment of sickle cell, a disease resear

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Stephen Fry was given addictive opioid painkiller OxyContin after fall

The Guardian - Pharmaceutical Industry

Actor was prescribed controversial high-strength drug to prevent loss of muscle after complex fractures of leg, hip and pelvis sustained on stage Stephen Fry was given the controversial painkiller OxyContin to help him to move again during his recovery from a serious fall. Now walking without a stick for the first time since the accident in September, Fry has revealed he was a reluctant user of the drug.

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STAT+: Was CAR-T therapy a bystander or driver of lymphoma? Researchers examine first published case

STAT

SAN DIEGO — Researchers on Saturday presented an unusual case of a T cell lymphoma marked with a CAR, the key synthetic protein in CAR-T therapy, here at the American Society of Hematology annual meeting. It is the first published case of the rare blood cancer that’s associated with a commercial CAR-T product, the Janssen/Legend Biotech drug Carvykti, or cilta-cel in this case.

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Opinion: STAT readers on diagnostic tests, marijuana regulation, and pediatric oncology

STAT

STAT now publishes selected Letters to the Editor received in response to First Opinion essays to encourage robust, good-faith discussion about difficult issues. Submit a Letter to the Editor  here , or find the submission form at the end of any First Opinion essay.

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2023 President of the American Society of Hematology Discusses Sickle Cell Disease Treatments for the 65th ASH Annual Meeting

Pharmacy Times

The president highlights a new curative treatment option for sickle cell disease while also expanding on the changing treatment landscape for hematologic conditions.

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