Mon.Feb 05, 2024

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COVID-19 Vaccination Rates Significantly Lower in Patients With Sickle Cell Disease

Drug Topics

Patients with SCD are more vulnerable to hospitalization due, in part, to SCD’s impact on the spleen, which filters infections in the blood and is a crucial organ for the immune system.

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‘Where you live shouldn’t determine how you get cancer’: An oncologist on global disparities

STAT

The prediction is dire: Cancer cases around the world are expected to surge 77% by 2050, a new report from the World Health Organization estimates. That attention-grabbing statistic, based on an analysis of 185 countries, cites a growing, aging population and factors including tobacco, alcohol, obesity, and pollution. Perhaps the most damning part of the report reveals the disparities determined by income.

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Trending Sources

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Pharmacist-led Primary Care Team Improves Clinical Outcomes in Severe Mental Illness

Pharmacy Times

This approach may help prevent premature deaths attributed to preventable or treatable cardiovascular disease.

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Wegovy is usually taken indefinitely. Amgen wants a version that can be tapered down

STAT

Amgen is trying a unique strategy with its obesity drug candidate: testing whether it can wean patients toward lower or less frequent doses over time. Very early data hints that Amgen’s candidate, called MariTide, may provide longer-lasting weight loss than highly popular obesity drugs on the market like Novo Nordisk’s Wegovy and Eli Lilly’s Zepbound.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Study Results Highlight Importance of Overcoming Stigma When Addressing Brain Health

Pharmacy Times

The study authors note that to effectively implement tools, processes, and strategies within practices, the stigma surrounding cognitive impairment must be addressed.

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STAT+: A sweeping new lawsuit against J&J asks: Are employers liable if they overpay for drugs?

STAT

Johnson & Johnson faces a consequential new class action lawsuit — not in its role as a manufacturer of drugs, but as an employer and purchaser of prescription drugs for its workers. Ann Lewandowski, a health care policy and advocacy director at J&J, sued her company on Monday for allegedly overpaying its pharmacy benefit manager for its employees’ medicines, citing previous STAT reporting to support some of the allegations.

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Medical devices with screens aren’t accessible to the blind. Congress has chance to change that

STAT

Katie Keim was diagnosed with type 1 diabetes in 1967 when she was eight, well before the era of insulin pumps or even reliable home testing. The condition started eating away at her vision 20 years later. By the time she was 36, her sight was completely gone.  Keim had lived an independent life as a child despite her illness. Her summers were spent exploring oceans with her family, not at diabetic summer camps.

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Data science in healthcare

pharmaphorum

Data science in healthcare is transforming the industry, from drug discovery to patient care. Learn about the role of data, artificial intelligence (AI), and the impact of initiatives like the NHS Datastore in revolutionising healthcare outcomes.

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Texas Medicaid agrees to fully cover gene therapy for Afghan refugees’ infant

STAT

After a months-long fight with Texas Medicaid over coverage of a gene therapy, Afghan refugees now have a chance to save their infant son. After initially balking , Texas officials have agreed to pay for the costly treatment, the boy’s family and his doctor told STAT. At the end of last week, N. Pashai’s cell phone rang. It was from a Minnesota area code.

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Novartis CEO’s 2023 pay rises 21% as Roche's helmsman nets $11M in his first year

Fierce Pharma

After leading Novartis and Roche through pivotal years in 2023, the CEOs of the Swiss drug giants each netted multimillion-dollar compensation packages. | After leading Swiss drug giants Novartis and Roche through pivotal years, their CEOs have each netted multimillion-dollar compensation packages for 2023.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Novo Holdings to purchase drug manufacturer Catalent for $16.5 billion, a deal that could expand Wegovy production

STAT

LONDON — The investment arm of Novo Nordisk’s parent foundation is buying drug manufacturer Catalent in a $16.5 billion deal, an acquisition that will give Novo additional sites as it builds up production of its booming obesity and diabetes drugs.   Under the deal, Novo Holdings is purchasing Catalent, a major contract development and manufacturing company with more than 50 sites globally.

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GSK details Blenrep combo data that could bring the multiple myeloma ADC back to life

Fierce Pharma

If a new package of pivotal data satisfies the FDA, GSK could have another run at the U.S. | If a new package of pivotal data satisfies the FDA, GSK could have another run at the U.S. multiple myeloma market with its previously withdrawn BMCA-targeted antibody-drug conjugate, Blenrep.

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A scholar of the patient ‘revolution’ tracks the arc from powerlessness to influence

STAT

At the end of each chapter in “Rebel Health: A Field Guide to the Patient-Led Revolution in Medical Care,” there’s a box. It summarizes the chapter, distilling what a reader just encountered into easy-to-digest bullet points. The author, Susannah Fox, admits she stole that idea from “The Long Covid Survival Guide,” which was written by patients for patients.

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Rural providers optimistic about financial stability, plan to expand services, Wipfli survey finds

Fierce Healthcare

Rural providers optimistic about financial stability, plan to expand services, Wipfli survey finds agliadkovskaya Mon, 02/05/2024 - 15:34

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: New Medicare Advantage rule is boon for providers, drag on insurers

STAT

Starting this year, private Medicare plans have to cover their members’ hospitalizations at the higher inpatient rate if their doctors predict they’ll have to stay beyond two midnights. It’s the same rule — appropriately called the two-midnight rule — that traditional Medicare has followed for a decade. After it came out that Medicare Advantage plans were routinely denying coverage for necessary services , the federal government decided they ought to be held to

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Cardiovascular Outcomes in Patients Intolerant to Statins Treated with Bempedoic Acid

Pharmacy Times

In December 2023, the FDA granted expanded indications for bempedoic acid and bempedoic acid plus ezetimibe in the treatment of primary hyperlipidemia.

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STAT+: Novo’s Catalent deal is great for GLP-1s. But what about drug manufacturing?

STAT

Sixteen billion dollars is a lot of money. But Monday’s announcement that the parent company of Novo Nordisk, the maker of the weight loss drug Wegovy, plans to buy Catalent , a company to which drugmakers outsource manufacturing, is probably even more important than it seems. The deal, done in part so that Novo can rapidly ramp up its ability to manufacture Wegovy, is a massive statement of optimism about the sales potential of that medication and weight loss drugs like it, known as GLP-

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Astellas' sales expectations are up for Padcev, down for Veozah

Fierce Pharma

Less than two months after the FDA approved the combination treatment of Astellas and Pfizer’s Padcev and Merck’s Keytruda in first-line bladder cancer, the Japanese company has

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Devoted Health’s losses in Medicare Advantage persist

STAT

Devoted Health has been one of the most prominent health insurance and provider startups of the past decade — founded and overseen by several alumni of former President Barack Obama’s administration. But it has not turned a profit after five years of selling Medicare Advantage plans to older adults, according to a STAT analysis of Devoted’s financial filings.

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Astellas raises Padcev forecasts on bladder cancer data

pharmaphorum

A bladder cancer study prompts Astellas to lift peak sales prediction for Padcev, although its menopause therapy Veozah isn’t ramping up as hoped.

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STAT+: Novartis to buy German biotech MorphoSys for $2.9 billion

STAT

Novartis said late Monday it has agreed to buy German biotech MorphoSys and its pipeline of cancer drugs for 2.7 billion euros, or $2.9 billion. The Swiss drugmaker will pay 68 euros, or around $73, per share, nearly twice Morphosys’s average trading price over the last month. At the center of the deal is pelabresib, a blood cancer pill that in November posted mixed results in a Phase 3 trial.

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Novo antes up $16.5B to poach CDMO giant Catalent amid Wegovy surge

Fierce Pharma

Late last month, Novo Holdings’ CEO Kasim Kutay hinted that the fund manager was eyeing buyouts as an outlet for its trove of Wegovy cash. Now, a major deal has materialized. | Late last month, Novo Holdings’ CEO Kasim Kutay hinted that the fund manager was eyeing buyouts as an outlet for its trove of Wegovy cash. Now, a major deal has materialized.

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In a 'spectacular collapse,' Cano Health files for bankruptcy

Fierce Healthcare

Cano Health today announced its intentions for file for bankruptcy in an effort to stay afloat after incurring nearly $1 billion in debt. | Cano said that it has secured a $150 million commitment in debtor-in-possession financing from some of its lenders, which is subject to court approval.

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Pre-Existing Depression, Anxiety Linked With Increased Risk of Insomnia After COVID-19 Infection

Drug Topics

Participants of a recent study who had pre-existing depression or anxiety were significantly more likely to develop insomnia.

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Target, locked

Drug Store News

Is the retailer still the hip, trendsetting option for beauty and wellness discovery among consumers?

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WuXi AppTec defends against 'blanket allegations' as US legislation casts shadow over certain Chinese drugmakers

Fierce Pharma

As new legislation stands to threaten the U.S. business of certain Chinese biopharma companies, CDMO giant WuXi AppTec has stepped in to make a case for itself. | The company's executives inked an open letter after the recent BIOSECURE act flagged WuXi AppTec and other Chinese drugmakers as potential national security threats.

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STAT+: Pharmalittle: We’re reading about Novo buying Catalent, Amgen’s obesity drug, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because that oh-so familiar routine of phone calls, online meetings, and deadlines has predictably returned. But you knew this would happen. After all, the world keeps spinning, at least for now. So time to give it a nudge in a better direction with a cup of delicious stimulation.

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Adalimumab Biosimilar Shows Efficacy in Noninfectious Uveitis

Pharmacy Times

Switching from adalimumab originator to SB5 did not cause clinically significant differences in treatment efficacy and safety for patients with noninfectious uveitis.

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Regeneron is interested in obesity treatments that combat muscle loss

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today, we talk about two players that want to join the obesity market with updates to the GLP-1 class: Amgen and Regeneron. Also, a draft bill in Congress would restrict U.S. involvement with Chinese biotechs.

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AbbVie’s new drugs keep post-Humira prospects on track

pharmaphorum

Better-than-expected sales of some of its new products, including Skyrizi and Rinvoq, helped AbbVie handle a sharp decline in sales of former cash-cow product Humira in the last quarter of 2023.

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10 natural remedies for high cholesterol

The Checkup by Singlecare

If your healthcare provider has recently expressed concern about your cholesterol levels, you’re not alone. About 86 million American adults have high cholesterol. Though high cholesterol does not usually cause symptoms, it can lead to high blood pressure, heart disease, stroke, and heart attack if left untreated. Fortunately, lifestyle changes—diet, in particular—can help you lower your cholesterol naturally. 10 home remedies for high cholesterol Along with a personalized action plan from a hea

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4DMT gene therapy cuts need for Eylea in wet AMD trial

pharmaphorum

4D Molecular Therapeutics' 4D-150 gene therapy for wet AMD has shown efficacy and a reduced need for eye injections with current therapy Eylea in a phase 2 trial.

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Hy-Vee dietitians offer 1,000 free Vitamin D screenings in February

Drug Store News

The retailer also is holding additional events to promote healthy lifestyles.

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