Wed.Apr 03, 2024

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Safely Experiencing the Once in a Lifetime Total Solar Eclipse

Drug Topics

It can be hard to look away from a once in a lifetime total eclipse, but it’s important to understand the risks that come with viewing.

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Epic plans to launch AI validation software for healthcare organizations to test, monitor models

Fierce Healthcare

As artificial intelligence rapidly advances in healthcare, the industry is grappling with how to evaluate AI models for accuracy and performance and monitor the technology for any downstream advers | The healthcare industry is grappling with how to evaluate AI models for accuracy and performance and monitor the technology for any downstream adverse outcomes.

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Trending Sources

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Meeting Preview: Turn the Tide at AAP’s 2024 Annual Conference

Drug Topics

This year’s conference, which is being held April 4 to 6 in San Diego, California, features talks from industry experts on developments in the pharmacy field, actionable skills, and informative CE sessions.

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Parkinson’s disease may be helped by GLP-1 drug, new study finds

STAT

The booming class of GLP-1 drugs that includes Ozempic and Wegovy is not only effective for diabetes and obesity, but is also showing early potential to help with conditions involving the brain, like mental health disorders , Alzheimer’s, and even, as new study results suggest — Parkinson’s disease. In a Phase 2 trial, patients with early Parkinson’s disease taking an older GLP-1 diabetes drug called lixisenatide experienced no worsening of motor symptoms over a year,

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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As antimicrobial resistance looms large, a nonprofit teams up with Big Pharma to intervene

PharmaVoice

AMR is a growing threat, but with little financial incentive to pick up the torch, government and nonprofit collaborations are keeping the R&D flames burning.

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STAT+: DNA test that predicts opioid addiction should be pulled off the market, critics urge the FDA

STAT

In the next 24 hours, more than 130 people will die from opioid-related drug overdoses. That will happen again tomorrow and the next day. Each year, the U.S. is losing roughly 110,000 people to these deaths of addiction, mostly from illicit opioids like heroin and fentanyl. Under pressure to help combat this public health crisis, the Food and Drug Administration has begun taking steps intended to reduce overdoses and opioid use disorder.

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STAT+: As AI proliferates, biopharma companies seek to harness it in clinical trials

STAT

For around 20 years, Avi Veidman spent his days in the Israeli intelligence community, analyzing satellite images. That was until 2017, when he founded a startup called Nucleai. Now, he’s scouring biopsy samples for cancer cells. Nucleai’s technology is not searching out signs of danger. Instead, the company’s technology maps the proximity of cancer cells, healthy cells, and proteins.

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Startup Manifold secures $15M for its AI-based clinical research platform

Fierce Healthcare

Initially founded as an AI lab in 2016, startup Manifold is using its AI expertise to modernize the tech infrastructure of clinical research organizations to help accelerate cancer studies. | Initially founded as an AI lab in 2016, startup Manifold is using its AI expertise to modernize the tech infrastructure of clinical research organizations to help accelerate cancer studies.

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Covid cut life expectancy by 1.6 years globally, but the leading causes of death haven’t changed since 1990

STAT

The leading causes of death haven’t changed since 1990 — with one glaring, pandemic-sized exception.  According to the latest analysis of the Global Burden of Disease study, which reviewed  deaths from 288 causes in over 200 states and territories, Covid-19 was the only condition that broke into the ranks — if only for two years — of the global population’s traditional top five killers: ischemic heart disease, stroke, chronic obstructive pulmonary dis

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Empower Prospective Pharmacists through Children’s Books

Pharmacy Times

This short story, illustrated by Roth, portrays pharmacists in a variety of settings and was written with the intent to introduce the career in a fun and understandable way for children and inspire kids to pursue their dreams.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Early data from rare-disease trial put spotlight on Moderna’s efforts to turn mRNA into medicines

STAT

LONDON — Moderna may be best known for its Covid-19 vaccine, but since its start, it’s always been set on developing therapies. It’s run into some hurdles as it’s pioneered turning mRNA — the strand of genetic material that’s at the heart of Moderna’s approach — into medicines. But the company’s vision of making cells into their own drug factories is showing signs of progress.

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HHS: Medicare incentives, penalties for hospitals could help stem drug shortages

Fierce Healthcare

To address the nation’s drug shortages, the Department of Health and Human Services (HHS) is floating a plan that would attach new Medicare payments and penalties to hospitals’ supply chain practic | A white paper penned by HHS outlines a potential program that would push hospitals toward inventory and purchasing practices that reinforce long-term supply chain resiliency.

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STAT+: FDA approves TriClip for tricuspid heart valve disease, pitting Abbott against Edwards

STAT

The Food and Drug Administration approved a new device from Abbott meant to treat tricuspid heart valve disease — an expected decision after an outside advisory panel voted that the device’s benefits outweighed its risks. The device, called the TriClip, addresses a disease called tricuspid regurgitation, in which blood leaks backward through the tricuspid heart valve.

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CVS rolls out tuition assistance, scholarship programs for pharmacists

Fierce Healthcare

CVS Health is aiming to bolster the pharmacy workforce with new scholarship and tuition assistance programs for people looking to enter the field. | CVS Health is aiming to bolster the pharmacy workforce with new scholarship and tuition assistance programs for people looking to enter the field.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Metronidazole Twice Daily: A Pharmacokinetic and Clinical Justification

Pharmacy Times

This medication is associated with a number of adverse effects, such as gastrointestinal upset and peripheral neuropathies, that may be mitigated by less frequent dosing.

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Why Automation with the Correct Liquid Handler is Integral to Improved NGS Outcomes

BioPharm

NGS abbreviates drug discovery timelines.

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Study: Biosimilar Competition Did Not Consistently Lower Costs for Patients

Pharmacy Times

The results indicate the need for targeted policies so that biosimilar competition can increase cost savings and affordability for patients with commercial insurance.

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Medicare price negotiations carry on as HHS responds to Big Pharma's IRA counteroffers

Fierce Pharma

Medicare drug price negotiations under the Inflation Reduction Act are steadily progressing after drugmakers recently submitted their counteroffers to the government's initial pricing proposals.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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A critical year for drug discount management

pharmaphorum

This critical year for drug discount management includes changes to the 340B programme, implications for Medicare, and updates on the Inflation Reduction Act.

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STAT+: Mass. senators assail Steward Health Care during hearing on firm’s struggling hospitals

STAT

Senators Ed Markey and Elizabeth Warren on Wednesday slammed Steward Health Care and its embattled leader Ralph de la Torre, blaming corporate greed and mismanagement for the  financial woes that have called into question the future of the for-profit company’s nine Massachusetts hospitals. “Steward Health Care, led by Dr. Ralph de la Torre, Cerberus [Capital Management], and Medical Properties Trust, and greedy corporate executives like them are failing in their responsibility

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Phytotherapy Has Myriad Uses In Clinical Practice

Pharmacy Times

This holistic approach to healing, grounded in harnessing the therapeutic properties of plants, serves as a bridge between centuries-old traditional wisdom and modern scientific practices.

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New data on liquid biopsy for colorectal cancer detection still underwhelms

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Today we talk about how biopharma plans to harness AI for clinical trial design, why two experts think Medicare ought to cover the costly GLP-1 drugs, and what news from Roivant means for its business strategy.

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Vanda secures FDA approval for Fanapt to treat bipolar I, 15 years after schizophrenia nod

Fierce Pharma

Fifteen years after gaining its first FDA approval for Fanapt (iloperidone) to treat schizophrenia, Vanda Pharmaceuticals has scored again with the same antipsychotic drug. | Fifteen years after gaining its first FDA approval for Fanapt (iloperidone) to treat schizophrenia, Vanda Pharmaceuticals has scored again with the same antipsychotic drug. The FDA has signed off on Fanapt tablets to treat adults with manic or mixed episodes associated with bipolar I disorder.

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Can you drink coffee while taking prednisone?

The Checkup by Singlecare

If you start your day with a cup of coffee, you’re in good company. The National Coffee Association reports that more Americans (up to 63%) drink coffee daily than any other beverage—including water. For a good reason—the caffeine it contains is good for an energy boost, and there are some notable health benefits. However, like most substances, there are health risks, such as anxiety and trouble sleeping , when consumed in excess.

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What Do The 2023 NAPLEX Pass Rates Mean For 2024?

Med Ed 101

The North American Pharmacist Licensure Examination (NAPLEX) is the clinical exam that allows a pharmacy graduate to become a licensed pharmacist. The NAPLEX is designed to evaluate your knowledge of pharmacy practice and is required for pharmacist licensure. It is a 6-hour exam composed of 225 questions, and students are allowed 5 attempts to pass […] The post What Do The 2023 NAPLEX Pass Rates Mean For 2024?

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Thermo Fisher plots layoffs at California plasmid manufacturing site as demand swings

Fierce Pharma

Demand fluctuations have spurred Thermo Fisher Scientific to downsize at the plasmid DNA manufacturing facility the company opened a little less than three years ago, putting jobs on the chopping b | Demand fluctuations have spurred Thermo Fisher Scientific to downsize at the plasmid DNA manufacturing facility the company opened a little less than three years ago, putting jobs on the chopping block.

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Basilea completes ceftobiprole marathon with FDA approval

pharmaphorum

Basilea Pharmaceutica gets US approval for its ceftobiprole antibiotic, around 15 years after the drug was first turned down by the FDA.

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STAT+: Investors funnel $275 million into Paragon Therapeutics spinout

STAT

Investors have funneled $275 million into a revamped biotech developing new psoriasis and psoriatic arthritis treatments that could be given just once or twice a year. The new Oruka Therapeutics launched Wednesday through a reverse merger with ARCA biopharma, a Colorado biotech that has undergone several iterations over the last 30 years. With the merger, ARCA’s plans are being cast aside in favor of Oruka’s antibody medicines, which came from spinout-generator Paragon Therapeutics

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SimBioSys and General Inception unite to revolutionize cancer drug development

Outsourcing Pharma

Precision oncology innovator SimBioSys and General Inception have joined forces in a strategic partnership aimed at revolutionizing cancer drug development.

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'Podnosis': A closer look at social prescribing and the impact of the arts on our health

Fierce Healthcare

Social prescribing is an emerging movement in healthcare, where providers may recommend personalized doses of arts and culture as part of a comprehensive care plan. | This week on "Podnosis," we explore the field of social prescribing and the role of arts and culture in shaping the future of mental health treatment.

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Women in Science: Dr Laura Trotta – ‘I joined CluePoints because of the research but also the mindset’

Outsourcing Pharma

Dr Laura Trotta joined CluePoints in 2015 and moved into her current role as vice president of research in January 2022, where she leads a team of research scientists responsible for developing new statistical and machine learning algorithms to assess the quality of clinical trial data.

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Commonwealth Fund launching task force on employer-sponsored coverage

Fierce Healthcare

Employer-sponsored coverage remains the main way half of Americans secure healthcare, and the Commonwealth Fund said Thursday that it would launch a new task force aimed at addressing affordability | Employer-sponsored coverage remains the main way half of Americans secure care, and the Commonwealth Fund said Thursday that it would launch a new task force aimed at addressing affordability and access.

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FDA approves Eko Health’s AI for heart failure detection

Pharmafile

Eko Health has announced that the US Food and Drug Administration (FDA) has approved its Low Ejection Fraction (Low EF) detection artificial intelligence (AI). This marks a significant step forward in detection of Low EF, with the tool detecting this within 15 seconds during a routine physical examination when using an Eko stethoscope. The Low […] The post FDA approves Eko Health’s AI for heart failure detection appeared first on Pharmafile.

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