Mon.Nov 27, 2023

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COVID-19 Hospital Admissions Could be More Accurately Predicted With Wastewater Data

Drug Topics

A new study found that models that included wastewater data were 15% more accurate when compared to models that only included clinical case data.

Hospitals 201
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There Are Increasing Opportunities for Community Pharmacies to Help Patients With Anemia in Condition Management

Pharmacy Times

Pharmacies have the potential to introduce testing services, promote public health campaigns, collaborate with anemia-led clinics, and get more prescribing rights to diagnose anemia.

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Trending Sources

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Opinion: The next Census could undercount the number of disabled Americans by 20 million

STAT

About 20 million disabled people will be erased if the U.S. Census Bureau moves forward with changes to disability data collection methods. That is because many disabled people will no longer be counted as disabled by the new questions the Census is proposing to use starting in 2025 with the annual American Community Survey (ACS). As disabled people, and as scholars who study disability measurement and use disability data for our research, we have grave concerns about this proposed change.

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Barriers to PrEP Access Continue to Grow Among Those Most at Risk of HIV

Pharmacy Times

Although social determinants of health (SDOH) have been a major barrier to access of preexposure prophylaxis for those who are at risk of HIV, commercial determinants of health pose a similar barrier.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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New research supports potential link between low-level lead exposure and liver injury

STAT

Nearly a decade on, the Flint water crisis still looms large in the minds of environmental toxin researchers. It was — and continues to be — evidence that not all communities in the United States are equally affected by environmental pollutants. “It’s true that they’re sort of ubiquitous, but they aren’t uniformly distributed.

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Progressions in HIV Research Compromised by COVID-19 Pandemic

Pharmacy Times

Study results indicate that outcomes were worse among those who inject illicit drugs and Black patients living with HIV.

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More Trending

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Ardent Health Services hit with ransomware attack, forcing hospitals in multiple states to divert ambulances

Fierce Healthcare

Hospitals in multiple states have been forced to divert ambulances and reschedule some elective patient procedures after U.S. | Hospitals in multiple states have been forced to divert ambulances and reschedule some elective procedures after U.S. hospital owner Ardent Health Services was hit with a ransomware attack.

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Scottish stem cell pro RoslinCT inks deal to produce Vertex and CRISPR's Casgevy

Fierce Pharma

Following the historic approval of the world’s first CRISPR-based gene-editing therapy in the United Kingdom this month, Vertex Pharmaceuticals has tapped its long-time manufacturing partner Roslin | RoslinCT, the CDMO arm of the Roslin Institute, is set to manufacture Vertex and CRISPR Therapeutics’ exa-cel “across the world” as part of Vertex’s global production network.

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Mark Cuban Cost Plus Drugs, Expion Health team to address specialty drug costs

Fierce Healthcare

Mark Cuban Cost Plus Drug Company has inked its latest partnership, joining forces with Expion Health to address the rising cost of specialty drugs. | Mark Cuban Cost Plus Drug Company has inked its latest partnership, joining forces with Expion Health to address the rising cost of specialty drugs.

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Long COVID study expanded across Europe

European Pharmaceutical Review

Biotech Berlin Cures, a company focusing on neutralising functional autoantibodies (fAABs), is expanding its Phase II clinical trial on Long COVID (post-COVID syndrome). into a pan-European, multi-center collaboration. The study will provide “meaningful and robust results on the efficacy and tolerability” of its lead drug candidate BC 007 in individuals with Long COVID.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Springworks wins FDA approval for drug to treat desmoid tumors

STAT

The Food and Drug Administration on Monday approved the first treatment for people with desmoid tumors, a localized cancer that invades soft tissue and muscle. The new drug, called Ogsiveo, is made by Springworks Therapeutics. It’s the company’s first approved medicine. Desmoid tumors are fibrous growths that start in connective tissue and are often found in the abdomen, arms, legs, and torso.

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Novo Nordisk keeps GLP-1 expansion spree rolling with $2.3B manufacturing upgrade in France

Fierce Pharma

After plotting $6 billion in production upgrades earlier this month, Novo Nordisk’s CEO Lars Fruergaard Jørgensen suggested the expansion outlay was just the start. | After plotting $6 billion in production upgrades earlier this month, Novo Nordisk’s CEO Lars Fruergaard Jørgensen suggested the expansion outlay was just the start. Now, some three weeks later, he’s putting his company’s money where his mouth is.

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A new algorithm unveils CRISPR ‘treasure trove’

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello! Hope you had a peaceful holiday. Back to biotech, we discuss the tough job market, delight in some exciting early developments in CAR-T and CRISPR, and see further validation for the blockbuster anti-inflammatory drug Dupixent.

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Do you need antibiotics for strep throat?

The Checkup by Singlecare

Strep throat is one of the most common reasons for a sore throat. About 5% to 15% of sore throats in adults and 20% to 30% of sore throats in kids are caused by a strep infection, which is caused by group A streptococcus bacteria. If you or your child has strep throat, you may rush to the doctor to request an antibiotic—but do you actually need antibiotics to treat strep?

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Sales of antibiotics for food-producing animals dropped by more than half in Europe over the past decade

STAT

Amid concerns over the use of medically important antibiotics given to food-producing livestock, sales of veterinary medicines across Europe dropped by 53% between 2011 and 2022, which regulators reported is the biggest drop ever recorded and a sign that campaigns to reduce usage are working. At issue is the extent to which antibiotics are given to these livestock to prevent and treat disease — a practice that has contributed to an alarming rise in antibiotic-resistant bacteria in humans.

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Pharma's Q3 growth rankings: GLP-1 drugs from Eli Lilly, Novo Nordisk were once again the big story

Fierce Pharma

Eli Lilly’s fortunes have turned quickly. | It was the second straight quarter where the overwhelming success of blood sugar regulating treatments were the dominant story in the biopharma industry. Eli Lilly and Novo Nordisk delivered the highest revenue gains, at 38% and 29%, respectively.

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STAT+: Most clinical trials run in Canada failed to take basic steps toward transparency, analysis finds

STAT

Just 3% of more than 3,700 studies run exclusively in Canada over a recent 10-year period were registered prospectively, reported results, and published the findings, underscoring ongoing concerns about clinical trial transparency, according to a new analysis. More specifically, 47% of those trials, or more than 1,770, were registered in advance, while only 12% reported results in a registry, and only 48% published their findings.

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Pharmacists Can Increase Access to Care for Patients With ATTR-CM

Pharmacy Times

Major barriers to care for patients with transthyretin amyloid cardiomyopathy (ATTR-CM) can include navigating therapeutics and the cost of medications.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Cultivating quality excellence in the clinical trials landscape

pharmaphorum

Cultivating quality excellence in the clinical trials landscape Mike.

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Noteworthy beauty brands

Drug Store News

DSN is keeping an eye out for beauty brands set to make waves on physical and digital shelves.

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Legalized medical cannabis five years on - Releaf discusses how far the industry hasn't come

Outsourcing Pharma

It is five years this month since a ground-breaking change in UK healthcare history happened â with doctors being able to prescribe cannabis-based medicines for the first time.

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EVERSANA brings genAI to medical content approvals

pharmaphorum

EVERSANA’s alliance with Amazon Web Services (AWS) on the application of generative artificial intelligence (genAI) to the pharma sector has borne its first fruit – a new tool to tackle the time-consuming and error-prone task of getting medical and regulatory content approvals.

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A look at budding innovation in state-based ACA marketplaces

Fierce Healthcare

With their recent stability, the Affordable Care Act marketplaces are well-positioned for innovation—but there's still room to take what's working nationwide, according to a new report. | With their recent stability, the Affordable Care Act marketplaces are well-positioned for innovation — but there's still room to take what's working nationwide, according to a new report.

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Prior Authorizations Pose Barrier to Access for HIV Preexposure Prophylaxis

Pharmacy Times

The study authors reported that plans in the South had the highest rates of exclusive PAs for either emtricitabine/tenofovir disoproxil fumarate or emtricitabine/tenofovir alafenamide even if the plan covered both, from 2018 to 2020.

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STAT+: Pharmalittle: Bioscience job market is upside down; Sanofi and Regeneron’s blockbuster Dupixent may find bigger market

STAT

Good morning, everyone, and nice to see you again after an extended break on this side of the pond. We hope your own respite was relaxing and invigorating, because that oh-so familiar routine of online calls and meetings and deadlines has predictably returned. But you knew this would happen, did you not? So time to fire up the coffee kettle and brew another cup of stimulation.

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As alcohol-related deaths climb, new drugs could curb the urge to drink

PharmaVoice

A drug developed by Kinnov Therapeutics halved alcohol consumption in heavy drinkers in a mid-stage study

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After market withdrawal, GSK touts positive Blenrep combo trial in multiple myeloma

Fierce Pharma

Is Blenrep back from the dead? After a positive trial readout, GSK sure hopes so. | Is Blenrep back from the dead? After a positive trial readout for the BCMA-targeted antibody-drug conjugate, GSK sure hopes so.

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Dupixent aces second COPD study, setting up FDA filing

pharmaphorum

Dupixent aces second COPD study, setting up FDA filing Phil.

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Silence Isn’t Golden: Two Executives Convicted in First Criminal Prosecution Under the Consumer Product Safety Act

The FDA Law Blog

By Riëtte van Laack & Anne K. Walsh — Although the Consumer Product Safety Act (CPSA) has been around for over 50 years to “protect the public against unreasonable risks of injury associated with consumer products,” it was not until 2008 that the statute was amended to authorize the Consumer Product Safety Commission (“CPSC”) to impose criminal liability against individual directors, officers, or agents of a corporation for violating the CPSA.

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Experts allay fears over pneumonia outbreak in China

pharmaphorum

Experts allay fears over pneumonia outbreak in China Phil.

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On a roll, Sanofi and Regeneron's Dupixent scores again in second COPD trial

Fierce Pharma

Sanofi and Regeneron’s Dupixent has scored in a second phase 3 study in chronic obstructive pulmonary disease (COPD), setting up the monoclonal antibody to become the first biologic to treat the lu | Sanofi and Regeneron’s Dupixent has scored in a second phase 3 study in chronic obstructive pulmonary disease (COPD), setting up the monoclonal antibody to become the first biologic to treat the lung disease and the first advancement in the indication in more than a decade.

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Lifeline for Wolman disease kids as NICE backs Alexion drug

pharmaphorum

Lifeline for Wolman disease kids as NICE backs Alexion drug Phil.

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Pfizer Study Shows COVID-19 Vaccination Reduces Symptoms, Improves Work Productivity

Drug Topics

Vaccinated study participants experienced fewer and less persistent symptoms, as well as fewer work hours lost, compared to unvaccinated participants.