Wed.Mar 20, 2024

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FDA Approves Aprocitentan For Treatment of Uncontrolled High Blood Pressure

Drug Topics

Aprocitentan (TRYVIO) from pharmaceutical company Idorsia demonstrated statistically significant and clinically meaningful reductions in blood pressure in combination with other antihypertensive therapies.

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New Compound Found in Edible Mushroom May Pave the Way for Antioxidant-Based Medicines

Pharmacy Times

The study represents a new era of research into mushrooms as a resource for pharmaceutical development.

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Focus On Obesity Management Before Addressing Comorbidities

Drug Topics

The latest guidelines advise managing obesity first, then treating a patient’s other conditions to produce optimal outcomes.

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STAT+: New gene therapy, to be priced at $4.25 million, has already transformed children’s lives

STAT

Every morning, Victoria Rasberry gets up before 6 a.m., walks to the bedroom down the hall, and helps her 8-year-old daughter Addi slide into a set of contraptions that squeeze and suck out the thick mucus constantly threatening to choke her airways closed. She feeds Addi breakfast through a stomach tube and makes sure she has the right mix of the 28 different medications required to keep her free of pain, infections, and seizures.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Meeting Preview: APhA 2024

Drug Topics

APhA 2024 will take place March 22 to March 25 in Orlando, Florida.

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Overdose deaths hit another record but show signs of leveling off

STAT

The U.S. recorded 107,941 drug overdose deaths in 2022, according to a new federal report — a total that marks an all-time record but also shows signs that the country’s overdose rate may finally be leveling off after years of steady increase. The 2022 total marks only a slight increase from the drug death toll of 106,699 the year before, according to the Centers for Disease Control and Prevention.

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More Trending

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Opinion: Sabbaticals for nurses could help fight worker shortages and burnout

STAT

A  new study  suggests that the nursing shortage is easing, but that doesn’t mean the health care system can stop worrying about retaining new and experienced clinicians. One potential solution: paid sabbaticals for nurses and other health care workers. If professors get sabbaticals to refresh and rejuvenate to sustain their academic productivity, why not frontline health care workers?

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Study Data Suggest SARS-CoV-2 Is Less Severe in Pediatric Patients

Pharmacy Times

Regardless, hygiene practices and prevention measures for SARS-CoV-2 should be strongly practiced to prevent all respiratory viruses.

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The U.S. banned asbestos, but its health impact will still be felt for decades

STAT

A new rule announced by the Environmental Protection Agency this week puts an end to the use of asbestos, a known carcinogen, in the United States. But researchers caution that we’ll likely still be dealing with the mineral’s public health harms for decades. The recently announced ban covers all forms of asbestos, including chrysotile asbestos, the only form still in use in the U.S., where it can be found in brake linings and is used to manufacture caustic soda (drain pipe cleaner)

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Mandatory Immunization of Health Care Workers Leads to Controversy

Pharmacy Times

Legal issues surfaced once again with the COVID-19 pandemic

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: J&J sues former employee for allegedly taking thousands of documents to a new job at Pfizer

STAT

Johnson & Johnson has accused a long-standing employee of taking thousands of confidential files about commercial strategies as he left for a similar job at Pfizer, according to lawsuit filed in a federal court in New Jersey. The health care giant alleged that Andrew Brackbill, who most recently worked in the Strategic Customer Group as director of trade channel strategy, downloaded files containing 10-year business plans across different therapeutic product areas; product launch strategies;

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Study: Lebrikizumab Demonstrates Improvements in Atopic Dermatitis for Patients of Color

Pharmacy Times

The efficacy data are consistent with other phase 3 studies, reinforcing lebrikizumab's potential as a first-line treatment across a range of skin tones.

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STAT+: Medicare expected to negotiate obesity drug prices soon, new analysis predicts

STAT

WASHINGTON — Medicare will likely choose the obesity drug semaglutide for price negotiation “within the next few years,” according to a new analysis from nonpartisan congressional budget experts. That could curb the cost of legislation requiring Medicare to cover obesity drugs, which would increase the chances of Congress actually passing such a bill.

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Star Power: Celebrity Endorsements in Public Health

Pharmacy Times

Celebrities, local advocates, patients, and pharmacists can effectively promote public health initiatives and raise disease awareness by authentically leveraging trusted relationships.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Immuno-oncology startup launches with $150 million, ex-Surface, Bluebird exec as CEO

STAT

Robert Ross had thought he would take more time off after his previous company, Surface Oncology, was acquired in September.  The immuno-oncology firm had just managed to weather the stormy public markets, which had battered its valuation. By the time it was acquired, Surface’s stock was trading at around $1 per share. But within a few months, Ross, an oncologist who previously worked at the Dana-Farber Cancer Institute before working at cancer startups like Surface and Bluebird Bio,

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BioNTech's shares tumble—again—amid continued COVID vaccine sales slide

Fierce Pharma

Four months ago, when BioNTech slashed its 2023 revenue projection from 5 billi | When BioNTech reported its fourth-quarter earnings Wednesday, it was another harsh reminder of the plummeting demand for COVID-19 vaccines. Sales came to 1.5 billion euros ($1.6 billion) for the fourth quarter and 3.8 billion euros ($4.1 billion) for 2023, coming up short of expectations.

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Tech company Artera adds new feature to revamp how providers complete referrals

Fierce Healthcare

Artera has spent the past nine years developing tech solutions to solve industrywide pain points and streamline patient communications. | Artera's tech helps healthcare providers deliver timely patient communications with automated referral outreach and real-time responses and automates pre-visit communications to make sure patients and staff are prepared for the appointment.

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Orchard sets out to sell world’s priciest gene therapy

PharmaVoice

Orchard is counting on the long-term data it’s accrued to convince insurers to cover Lenmeldy’s $4.25 million list price, the highest of any genetic medicine to come to market.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: A scientific mystery highlights the blind spots in genomics databases

STAT

The two patients had both died young from heart problems. When researchers looked at their DNA, they spotted another commonality: The two shared a particular version of a gene that helps the heart beat. Perhaps, the researchers thought, the variant could explain their heart conditions. Genomic datasets indicated the variant was rare, meaning it could be the cause of a rare disease.

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With historic MASH approval, Madrigal preps for launch and a public offering

PharmaVoice

After snagging the first approval for MASH, Madrigal Pharmaceuticals’s drug is primed to become a blockbuster.

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Employee experience in healthcare: The importance of EX for patient experience

pharmaphorum

Understanding the employee experience in healthcare is essential for improving the patient experience. Learn more about the importance of employee experience in healthcare and how it impacts patient care.

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Ophelia's virtual OUD care now in-network for Medicaid, dual-eligible Highmark Wholecare members

Fierce Healthcare

Ophelia, a virtual provider of opioid use disorder (OUD) treatment, is now in-network for Highmark Wholecare members. | Ophelia has been part of Highmark Health’s network in Pennsylvania since 2021, serving 2.9 million commercial members. It is now in-network for Wholecare Medicaid and dual-eligible members. Ophelia works with 13 Medicaid plans overall.

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AI and the battle against AMR

pharmaphorum

Discover how AI is being utilised in the fight against antimicrobial resistance (AMR), particularly in addressing MRSA infections.

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PocketHealth lands $33M to build out its medical image exchange platform

Fierce Healthcare

PocketHealth, a medical image exchange platform, has raised $33 million in a series B round. | PocketHealth, founded in 2016 by Rishi and his brother Harsh, gives patients instant access to their medical images from partner providers and enables image exchange between providers.

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Vicore’s lung disease digital therapy gets breakthrough tag

pharmaphorum

Vicore gets FDA breakthrough status for Almee, a cognitive behavioural therapy (CBT) digital health therapy used to support people with pulmonary fibrosis

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Amedisys says Oregon regulators are reviewing its $3.7B acquisition by UnitedHealth

Fierce Healthcare

Amedisys disclosed Tuesday that Oregon regulators are probing the company's potential acquisition by UnitedHealth Group. | Amedisys disclosed Tuesday that Oregon regulators are probing the company's potential acquisition by UnitedHealth Group.

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Johnson & Johnson accuses former employee of taking thousands of files to new role at Pfizer

Fierce Pharma

As two of the world’s largest pharmaceutical companies, Johnson & Johnson and Pfizer have long been rivals in various therapeutic areas. | The company is accusing former employee Andrew Brackbill of downloading thousands of confidential strategy-related files before leaving for rival Pfizer.

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Flashback: 2005 Tennessee Medicaid disenrollment led to increased crime, study finds

Fierce Healthcare

Large-scale Medicaid disenrollment in Tennessee nearly 20 years ago led to increased total crime rates, a new study by the National Bureau of Economic Research found. | A new study, that draws parallels to current day redeterminations, delves into the relationship between mass Medicaid disenrollment in 2005 and how it may have led to violent crime.

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Orchard’s MLD gene therapy becomes costliest US medicine

pharmaphorum

Orchard Therapeutics has revealed the US price of Lenmeldy, its gene therapy for rare disease MLD, placing a $4.

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Johnson & Johnson’s paediatric HIV-1 treatment secures FDA approval

Pharmaceutical Technology

Johnson & Johnson has received approval from the FDA for EDURANT PED to treat human immunodeficiency virus-1 (HIV-1) in children.

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Novo is building a really big computer

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning, everyone. Damian here with the latest megaround in biotech venture capital, a rough month for biotech’s neuroscience renaissance, and Novo Nordisk’s big computer.

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7 foods to avoid while taking metformin

The Checkup by Singlecare

Metformin is an FDA-approved drug for the treatment of Type 2 diabetes. It has a long history of success in lowering blood sugar levels, especially when combined with diet changes and exercise. Although metformin is only approved for use in treating Type 2 diabetes, it has several off-label uses, including as a treatment for polycystic ovary syndrome (PCOS), gestational diabetes, and drug-induced weight gain.

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FDA approves innovative gene therapy for MLD

European Pharmaceutical Review

The US Food and Drug Administration (FDA) has approved gene therapy Lenmeldy (atidarsagene autotemcel) as the first treatment for children with early-onset metachromatic leukodystrophy (MLD). Following a patient receiving chemotherapy, the autologous hematopoietic stem cell-based gene therapy is administered as a personalised, one-time, single-dose infusion.

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