Mon.Jul 08, 2024

article thumbnail

Semaglutide Use Increases Risk of Optic Neuropathy

Drug Topics

Researchers addressed the association between semaglutide use and the risk of nonarteritic anterior ischemic optic neuropathy.

200
200
article thumbnail

STAT+: Troubled for-profit chains are stealthily operating dozens of psychiatric hospitals under nonprofits’ names

STAT

Come quickly, the Columbus Police sergeant urged, patients are in danger. The psychiatric hospital on the city’s east side may need to be shut down, he warned Ohio regulators. The officer, a 27-year veteran of the department, knew that sending the February letter was an unusual thing to do, but meetings with hospital leaders had gone nowhere, and he was at his wit’s end.

Hospitals 145
Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Trending Sources

article thumbnail

SGLT2i, GLP-1RA Combination Therapy Offers Robust Protection Against Cardiovascular, Kidney Disease

Drug Topics

When used together, sodium glucose co-transporter 2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) were able to lower the risk of major adverse cardiovascular events and kidney disease by 11% and 33%, respectively.

178
178
article thumbnail

Opinion: EcoHealth Alliance: Covid’s anti-science mob extracting its pound of flesh

STAT

Imagine this post-9/11 scenario: A New York City fire company is forced to shut down and lay off its firefighters because some Americans believe a bizarre conspiracy theory that this fire company brought down the World Trade Center towers. A Covid-19 version of this freakish tale is happening today. Instead of a fire company, the conspiracy gang is targeting an important, successful, decades-old nonprofit organization that researches viral epidemics and tries to predict and forestall future 

145
145
article thumbnail

Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

article thumbnail

Digital health funding hit $5.7B through June, on track to surpass 2019 and 2023, Rock Health reports

Fierce Healthcare

U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year. | U.S. digital health startups pulled in $5.7 billion across 266 deals in the first six months of 2024, marking continued momentum in the sector after a rocky few quarters last year.

138
138
article thumbnail

STAT+: A faster, simpler, cheaper cancer cell therapy is about to be tested in humans

STAT

In a long-awaited study, patients in Australia will soon receive an IV infusion designed to transform their own immune cells into swarms of cancer-fighting drones. The trial, announced on Tuesday by Interius Biotherapeutics, will be the first to test what’s known technically as in vivo CAR-T therapy. Researchers have long hoped the approach could provide a potentially cheaper, safer, and more scalable version of the cell therapies that are curative for some blood cancer patients but remai

More Trending

article thumbnail

New study sparks debate about whether H5N1 virus in cows is adapted to better infect humans

STAT

A study published Monday provides new evidence that the H5N1 virus currently causing an outbreak of bird flu in U.S. dairy cattle may be adapted to better infecting humans than other circulating strains of the virus, a result that is already courting controversy among the world’s leading flu researchers. Across the globe, different influenza viruses are constantly circulating in many different kinds of animals.

143
143
article thumbnail

Physician burnout drops below 50% for first time since 2020, AMA poll finds

Fierce Healthcare

The portion of physicians surveyed by the American Medical Association (AMA) who report at least one symptom of burnout has dropped below 50%, a first since the onset of the COVID-19 pandemic. | The American Medical Association, which often cites burnout as a key threat to the well-being of the profession and the long-term supply of medical professionals, celebrated the results but said there’s still work to be done.

124
124
article thumbnail

Opinion: The ethical implications of Elon Musk’s unorthodox approach to medical science

STAT

Medical milestones broadcast via tweet. Scientific progress revealed via live YouTube demo. Teasers for updates followed by a livestream from a patient’s home. These aren’t the latest social media influencer tactics, but the way Neuralink, Elon Musk’s neurotechnology company, has disseminated information about its medical research.

article thumbnail

Telemental health visits decline when cost-sharing returns, new study finds

Fierce Healthcare

In a study published in JAMA Network Open on Tuesday, Included Health and Harvard Medical School found that patients in high deductible health plans are less likely to seek virtual behavioral healt | A study by Included Health and Harvard Medical School found that when cost-sharing is reintroduced for telehealth visits for patients in high-deductible health plans, patients will use fewer services.

article thumbnail

What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

article thumbnail

STAT+: Biden administration appeals jury finding in battle over patents for HIV prevention pills

STAT

The Biden administration has appealed a decision in which a federal court jury last year sided with Gilead Sciences over the rights to a pair of groundbreaking HIV pills — and at least $1 billion in royalties may be at stake. At issue is a battle over patents for Truvada and a newer, upgraded version version called Descovy — two highly effective and lucrative medications — as well as the role played by the federal government in making it possible to prevent transmission of a

139
139
article thumbnail

Maternal RSV Vaccination Not Associated With Increased Preterm Birth Risk

Drug Topics

Current recommendations suggest women receive the RSV vaccine between 32 and 36 weeks' gestational age.

Vaccines 145
article thumbnail

Bird flu snapshot: Live H5N1 virus grown from raw milk samples as Delaware moves to legalize its sale

STAT

Bird flu snapshot: This is the latest installment in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates, you can also subscribe to STAT’s Morning Rounds newsletter. Last week, following an unusually udder pun-laden discussion , lawmakers in Delaware voted to become the latest state to legalize the sale of raw milk.

138
138
article thumbnail

HHS announces $27.5M in funding to address women's behavioral health needs

Fierce Healthcare

A variety of government and healthcare organizations are now eligible to tap into newly announced funding by the Department of Health and Human Services. | The funding will support community-based maternal behavioral health services and a women’s behavioral health technical assistance center.

122
122
article thumbnail

5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

article thumbnail

STAT+: South Africa and J&J reach a deal to widen access to a key tuberculosis treatment

STAT

South African antitrust authorities ended an investigation into Johnson & Johnson and its Janssen subsidiary over “excessive pricing” of a lifesaving tuberculosis drug after the companies took steps to lower the cost and widen access to the medicine. In a brief statement , the Competition Commission explained that J&J and Janssen agreed not to enforce a so-called secondary patent on bedaquiline, which is also sold under the brand name Sirturo, a step that makes it possible

127
127
article thumbnail

ONC leader and FDA official step down from Coalition for Health AI

Fierce Healthcare

Two high-ranking government officials have abdicated their roles on the board of the Coalition for Health AI, the organization and HHS confirmed. The breakup is a strong departure from th | Micky Tripathi and Troy Tazbaz have officially stepped down from their Board-level federal liaison roles at the Coalition for Health AI, one of the nation's largest healthcare AI standards organizations.

FDA 122
article thumbnail

Lilly's Mounjao triggers more weight loss than Novo Nordisk's Ozempic: study

Fierce Pharma

Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? | Is Eli Lilly’s Mounjaro or Novo Nordisk’s Ozempic more effective in helping patients lose weight? While a head-to-head trial pitting the two treatments remains ongoing, new evidence shows that Lilly’s tirzepatide may be the superior weight loss product.

121
121
article thumbnail

Pandemic policies have fewer adults skipping medical care due to cost

Fierce Healthcare

Nearly 5 million fewer people delayed care from 2019 to 2022, a study from the Urban Institute with funding from the Robert Wood Johnson Foundation revealed. | Pandemic-era policies appear to have helped almost 5 million people access necessary medical care that they otherwise may not have been able to, a recent report shows.

119
119
article thumbnail

Survey: Dry Eye Is Common, But Americans Remain Uneducated About the Condition

Drug Topics

Results of a new survey show that individuals with dry eye believe the condition is something “people must learn to live with.

112
112
article thumbnail

STAT+: AI leads the way as health tech funding inches toward a post-pandemic stability

STAT

Funding for health tech startups in the first half of 2024 remained far below the high levels seen immediately after the Covid-19 pandemic, but several indicators suggest stability — and maybe even a brewing comeback for the sector. Health tech startups raised $5.7 billion in the first half of the year, putting them on pace to just exceed the $10.7 billion total raised in 2023, according to a report from Rock Health , which invests in companies and provides advisory services.

110
110
article thumbnail

Merck puts 1,000-plus Zostavax lawsuits to bed after plaintiffs file for dismissal

Fierce Pharma

After a drawn-out litigation process, Merck & Co. seems to have finally washed its hands of more than a thousand lawsuits tied to its shingles vaccine Zostavax. | A U.S. appeals court has tossed a request to resurrect certain lawsuits claiming Merck’s popular shot Zostavax caused patients to develop shingles. The court made its decision after the plaintiffs filed a voluntary dismissal some two years after logging a loss in Pennsylvania.

Vaccines 105
article thumbnail

STAT+: Pulling back the curtain on psychiatric hospital joint ventures

STAT

You’re reading the web version of Health Care Inc., STAT’s weekly newsletter following the flow of money in medicine. Sign up to get it in your inbox every Monday. Lifting the veil on psychiatric hospital joint ventures Nonprofit hospital systems are opening psychiatric hospitals to help the growing number of people suffering from mental  health  problems.

Hospitals 107
article thumbnail

Machine Learning Model Accurately Predicts Intravenous Immunoglobulin Non-Responders For Kawasaki Disease

Pharmacy Times

By developing the Shizuoka score, which features a new predictive model using machine learning, patients with Kawasaki disease who are non-responders to intravenous immunoglobulin were able to be accurately identified.

105
105
article thumbnail

STAT+: Eli Lilly to acquire Morphic for $3.2 billion

STAT

Eli Lilly said Monday it will acquire Morphic Holding, a biotech developing a treatment for inflammatory bowel disease. Lilly will pay about $3.2 billion to buy the Waltham, Mass.-based company. That translates to $57 per share, a premium of roughly 79% from Morphic’s Friday closing price. Morphic’s lead candidate, MORF-057, is an oral small molecule that blocks α4β7 integrin.

106
106
article thumbnail

CDMO Lotte breaks ground on $3.3B production plant in Korea, touts growth goals

Fierce Pharma

After announcing plans last year to expand manufacturing in its home country, Korean CDMO newcomer Lotte Biologics has kicked off work on a sprawling facility along Incheon’s waterfront near Seoul. | Late last week, Lotte Biologics broke ground on its flagship facility at the Songdo Bio Campus in Incheon International City, South Korea. The company is pitching the production effort as a key part of its quest to become one of the top 10 CDMOs in the world.

102
102
article thumbnail

Is Shingrix free for seniors?

The Checkup by Singlecare

The Centers for Disease Control and Prevention (CDC) estimates that 1 million Americans get shingles every year , and the National Institute on Aging says about half of those cases are in adults ages 60 or older. Shingles (herpes zoster) are caused by the varicella-zoster virus, which also causes chickenpox. Shingles can cause a painful rash, blisters, and post-herpetic neuralgia (PHN).

article thumbnail

Novo's Ozempic, Wegovy linked to potential eye problem? Not so fast, analysts say

Fierce Pharma

Novo Nordisk’s massively successful GLP-1 analog semaglutide, the active ingredient in the popular diabetes and obesity meds Ozempic and Wegovy, may be linked to a vision loss disorder, a new | Novo Nordisk’s popular GLP-1 analog semaglutide may be linked to a vision loss disorder, a study suggests. But one team of analysts cautioned against reading too much into the analysis.

98
article thumbnail

How long does it take Adderall to work?

The Checkup by Singlecare

Adderall, sold under the generic version of amphetamine/dextroamphetamine) is a stimulant medication approved by the U.S. Food and Drug Administration to treat the symptoms of attention deficit hyperactivity disorder ( ADHD ). Adderall is also used to help people with narcolepsy stay awake during the day. There are two types of Adderall: Adderall IR and Adderall XR.

Dosage 98
article thumbnail

Healthcare report finds declining public trust in institutions

pharmaphorum

A recent healthcare report conducted by Edelman reveals a concerning trend of declining public trust in healthcare institutions. Explore the key findings and implications in this comprehensive analysis.

97
article thumbnail

Rinvoq for atopic dermatitis

The Checkup by Singlecare

Atopic dermatitis, also known as eczema , is a skin condition that causes dry, itchy, irritated skin. According to the National Institutes of Health , eczema affects 15%–30% of children and 2%–10% of adults at some point in their life. There is no cure for eczema , but symptoms can be managed with moisturizers, topical corticosteroids , systemic treatments, or a combination of them all.

article thumbnail

The biotech news you missed this week

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Hello! Hope your weekend was a blissful one. Today, we talk about AbbVie’s outsize marketing spend, see how GLP-1s are impacting cancer rates, and more.

FDA 96
article thumbnail

Is Dupixent covered by Medicare?

The Checkup by Singlecare

Dupixent (dupilumab) is a brand-name medication that has been approved by the Food and Drug Administration (FDA) to treat the following conditions: Moderate-to-severe atopic dermatitis (the most common type of eczema) in adults and children 6 months and older Moderate to severe eosinophilic asthma or asthma that is dependent on oral steroid medications in adults and children 6 years and older Chronic rhinosinusitis with nasal polyps in adults 18 years and older Prurigo nodularis in adults 18 ye

article thumbnail

Avoiding Weight-Loss Pitfalls: How Organizations Can Strengthen Their Medication Strategy

Pharmacy Times

When used correctly, weight-loss medications, such as glucagon-like peptide-1 (GLP-1) medications, can be a tool to help reduce costs and provide clinical results.

132
132
article thumbnail

Vraylar and pregnancy: Important safety considerations

The Checkup by Singlecare

People with certain mood disorders, such as schizophrenia and bipolar disorder , may be prescribed a drug called Vraylar (cariprazine) to help manage their symptoms. It’s an atypical antipsychotic medication that affects both dopamine and serotonin receptors, says Alyssa Dweck, MD , OB-GYN and women’s health expert for INTIMINA. It’s also relatively new: Vraylar came on the market in 2015, and the Food and Drug Administration (FDA) has been slowly approving it for different uses since the