Tue.May 21, 2024

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Omega-3 Fatty Acids May Lower Colorectal Cancer Risk

Drug Topics

Research presented at Digestive Disease Week suggests that including omega-3 rich foods, or omega-3 supplements, into a healthy diet could offer additional protection against colorectal cancer alongside regular screening.

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Move over, wastewater. Store-bought milk could be another way to track the bird flu outbreak in cows

STAT

Scientists from the University of Washington and the Fred Hutchinson Cancer Center have managed to generate a full genetic sequence of H5N1 virus from milk, a development they suggest means commercially purchased milk products could be used to monitor the progress of the bird flu outbreak in dairy cattle and to check for important changes in the virus over time.

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FDA Grants Breakthrough Therapy Designation to Inavolisib for PIK3CA-Mutated Breast Cancer

Pharmacy Times

Inavolisib was submitted to the FDA for review as a first-line treatment for advanced HR-positive, HER2-negative PIK3CA-mutated breast cancer.

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How doctors are pressuring sickle cell patients into unwanted sterilizations

STAT

BATON ROUGE, La. — The surgery was supposed to alleviate worry, but now, years later, Whitney Carter’s mind kept flicking back to it, wondering if it could be undone. She sometimes descended into these moods, taciturn, withdrawn, as if all hope had gone extinct. She sat on the couch in the half-light, blinds shut against the heat. The whole thing made her feel less than, like some essential part of her had been removed.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Program Highlights Opportunities for Community Pharmacies to Deliver Screening, Education, and Referral Interventions

Pharmacy Times

Aligning community pharmacy interventions with top-down findings, payers’ population health priorities, and identified unmet needs can help develop a sustainable pathway.

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CDC asks states and cities to keep flu surveillance at peak levels because of bird flu threat

STAT

The Centers for Disease Control and Prevention asked local and state health officials Tuesday to maintain flu surveillance operations at peak-season levels over the summer in a bid to remain watchful for any signs of human-to-human spread of the H5N1 bird flu virus. Flu surveillance activity is generally conducted at low levels during the late spring and summer months, in recognition of the fact that as temperatures rise, transmission of seasonal flu viruses drops to minimal levels in the Northe

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Black Americans’ risk for breast cancer gains clarity in analysis of 40,000 genomes

STAT

Hundreds of genetic variants can nudge someone’s risk of breast cancer up or down or towards a particular subtype. The studies identifying those gene variants, though, have largely involved people with European ancestry and thus give a less accurate picture of breast cancer risk for people who are not white. That’s beginning to change.

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Advancement in CAR T Cell Therapy for Patients with Multiple Myeloma Helps Predict Treatment Response and Resistance

Pharmacy Times

Researchers from the University of Leipzig Medical Center identify multiple biomarkers associated with the success of CAR T cell therapy in relapsed multiple myeloma.

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STAT+: GSK’s asthma push continues as drug succeeds in Phase 3 trials

STAT

A new asthma treatment that could be administered just once every six months has succeeded in two Phase 3 trials, developer GlaxoSmithKline announced Tuesday. The drug, depemokimab, is designed to treat asthma by targeting a protein called interleukin-5, or IL-5. The protein is linked to the type of inflammation found in most severe asthma cases, according to the pharma company.

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Study Evaluates Use of Milvexian in Secondary Stroke Prevention

Pharmacy Times

The results showed that individuals treated with milvexian had a prolonged aPTT in a dose-dependent manner with limited effects of PT.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Cadence finds reduced cost and better outcomes for heart failure patients through remote monitoring program 

Fierce Healthcare

A new paper published in the Journal of Cardiac Failure shows that patients on Cadence’s remote physiologic monitoring program had better outcomes than patients eligible for the program wh | Deaths from heart failure are rising. National remote monitoring company Cadence published new evidence that RM for heart failure with reduced ejection fraction (HFrEF) could be the missing link in heart failure treatment.

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Opinion: As a primary care physician, here’s how I hope to partner with AI

STAT

I am both excited and terrified by the entrance of artificial intelligence into my primary care practice. AI’s enormous potential to help clinicians become more focused on patients, available, diagnostically accurate, and efficient feels like a dream. Yet memories of the nightmarish introduction of the electronic heath record into clinicians’ work lives looms like a dark cloud.

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Pharmacists’ Impact on Care for Patients With Alzheimer Disease

Pharmacy Times

Results from the INCREASE study shed light on the value of the pharmacist in medication therapy management.

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STAT+: At a flashy new research hub, AstraZeneca lays out ambitious growth goals

STAT

CAMBRIDGE, England — On a bit of a roll, AstraZeneca on Tuesday laid out ambitious growth goals for the rest of the decade, seeking to build on its momentum in fields like oncology as it said it would nearly double its revenue to $80 billion by 2030. Hitting such a target would depend on the launch of 20 new medicines and continued growth of its cancer and rare disease therapies, as well as other drugs.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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Precision medicine company Tempus AI files to go public

Fierce Healthcare

Three years after talks of an IPO surfaced, health tech company Tempus AI lit the fuse and is looking to go public this year. | Founded in 2015, Tempus says it’s built the world’s largest library of clinical and molecular data along with an operating system to make those data accessible and useful for providers to inform patient care.

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A letter from the executive editor: Investigation reveals how doctors have pressured sickle cell patients into sterilizations

STAT

Dear Readers, I want to bring your attention to a deeply disturbing but vital series of stories STAT is publishing beginning today.  It reveals that an injustice often relegated to the distant past persists to this day: For decades, physicians have steered sickle cell patients toward sterilization, their stories echoing the ugly history of eugenics in America.

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A Novel Bispecific Anti-GPRC5D × CD3 Antibody: A New Treatment Paradigm in Multiple Myeloma

Pharmacy Times

Investigators assessed the efficacy of BsAb5003 in treating multiple myeloma, with the results showing that the therapy may be an effective treatment approach.

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Opinion: Reports of telehealth’s death have been greatly exaggerated

STAT

“Telehealth is collapsing.” “Telehealth is going through a contraction.” “There is a dark cloud hovering over virtual care.” These are just a few of the doomsday views sparked by the news that Optum and Walmart are shutting down their virtual care businesses. Many industry observers, connecting the dots to the current struggles of legacy telehealth providers , have concluded that virtual care is in trouble.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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FDA Grants Breakthrough Therapy Designation for Larsucosterol in Alcohol-Associated Hepatitis

Pharmacy Times

The primary outcome was a 90-day incidence of mortality or liver transplant for individuals who received larsucosterol, compared to the placebo group.

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STAT+: AltruBio raises $225 million to develop ulcerative colitis drug and other immune checkpoint enhancers

STAT

Checkpoint inhibitors, drugs that unleash the immune system, have turned into blockbuster therapies that have transformed outcomes for some patients with deadly cancers. AltruBio, a Bay Area biotech, is betting it can help patients suffering from autoimmune and inflammatory diseases by taking the opposite tack: pumping the brakes on runaway immune responses.

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Tianeptine Misuse Raises Concerns Across US, but is Stigmatizing the Drug Helpful?

Drug Topics

Unregulated tianeptine, often referred to as “gas station heroin,” has led to serious adverse effects. But while health officials warn the public about its potential dangers, others are concerned stigmatization could ruin any future chance of the drugs medicinal use.

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AstraZeneca, on fast track of growth, sets revenue target at $80B by 2030

Fierce Pharma

A decade ago, with AstraZeneca in decline and some investors urging the drugmaker to sell out to Pfizer, new CEO Pascal Soriot presented an audacious plan to hike revenue to $45 billion by 2023. | After AstraZeneca achieved Pascal Soriot's ambitious $45-billion-by-2023 revenue goal, the CEO is thinking big again. On Tuesday morning, AZ unveiled its new plan to swell its revenue to $80 billion by 2030.

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AstraZeneca sets lofty target of $80bn in revenues by 2030

pharmaphorum

AstraZeneca CEO Pascal Soriot says group revenues can reach $80bn by 2030, fuelled by a pipeline that features 'many' potential $5bn-plus candidates.

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Lilly doubles down on radiopharma

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. Please take some time today to read  this story  from my colleague Eric Boodman, who spent a year investigating how doctors are pushing sickle cell patients to get unwanted sterilizations. This is the first story in a new series from STAT called  Coercive Care.

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FDA competition seeks digital endpoints for Parkinson’s

pharmaphorum

FDA is asking artificial intelligence teams to develop a digital endpoint tool to study freezing of gait, a symptom of Parkinson’s that can have a serious impact on patients.

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3 up-and-coming US biotech hotspots

PharmaVoice

These three U.S. cities are putting themselves on the biotech map as unsung hubs of the industry.

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The commercialisation of quantum science in pharma

pharmaphorum

In today’s podcast, web editor Nicole Raleigh speaks with PASQAL’S technical business developer Europe, Krisztian Benyo, PhD, about the pharma applications and commercialisation of quantum science.

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Examining Immune Response of Hepatitis B Vaccines in Patients With HCV

Drug Topics

Research presented at DDW 2024 found there was no significant association between immune response and hepatitis B vaccine types in patients with Hepatitis C.

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Closing the bipolar diagnosis gap for Black Americans

pharmaphorum

Despite the rate of bipolar disorder being the same among Black Americans as other Americans, there exists a significant disparity in diagnosis and subsequent treatment. Many Black Americans with bipolar disorder remain undiagnosed and untreated.

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FDA Approves Aflibercept (Eyela) Biosimilars, Yesafili and Opuviz

Drug Topics

These aflibercept biosimilars are used to treat wet age-related macular degeneration, diabetic macular edema, and diabetic retinopathy.

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Incyte plots Delaware expansion as it looks to re-wed commercial, medical teams in its home state

Fierce Pharma

As Incyte Corporation continues its growth momentum thanks to JAK inhibitors Jakafi and Opzelura, the company is bringing its U.S. | Incyte revealed plans to purchase buildings at 1100 North King Street and 1100 North French street in downtown Wilmington, Delaware, where the company got its start back in 2002.

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EU rules PTC’s Duchenne drug can stay on the market

pharmaphorum

Going against the advice of the CHMP, the EU has said that PTC Therapeutics’ Translarna therapy for Duchenne muscular dystrophy should stay on the market

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19 Pharmacy Certifications to Advance Your Practice

PioneerRx

As independent pharmacy continues to go clinical, you’ve probably found yourself considering adding a service, expanding a program, or in this case, tacking on.