Mon.Aug 05, 2024

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Online Pharmacies Are Illegally Selling GLP-1s Without Prescriptions

Drug Topics

A study found that test products purchased from illegal online pharmacy operations had lower purity levels and significantly more semaglutide content than what was advertised on the label.

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Human Pluripotent Stem Cell Line Variability Supports Successful Cortical Organoid Production

Pharmacy Times

Small adjustments in human pluripotent stem cell cultures and the molecule concentration patterns in the initial 5 days of differentiation are essential to “rescue” the lines.

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Trending Sources

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Novartis and Viatris sued by estate of Henrietta Lacks, whose cells were extracted for research in 1951

Fierce Pharma

The family of a Baltimore woman whose cells were extracted for medical research without her consent more than 70 years ago has filed another lawsuit against drugmakers that allegedly profited from | The family of a Baltimore woman whose cells were extracted for medical research without her consent more than 70 years ago has filed another lawsuit against drugmakers that allegedly profited from the discoveries they made using her genetic material.

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Report: Satisfaction of Mail-Order Pharmacies Rise, Decreases for Community Pharmacies

Pharmacy Times

Customers report that their communication is strong with their pharmacists, but only 51% said their pharmacist was trustworthy.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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BioNTech posts €808M loss as company continues to come to grips with seasonal COVID vaccine market

Fierce Pharma

While Pfizer’s German mRNA partner BioNTech has high hopes for its post-COVID future, the company continues to feel the squeeze from the changeover to a seasonal vaccine market. | While Pfizer’s German mRNA partner BioNTech has high hopes for its post-COVID future, the company continues to feel the squeeze from the changeover to a seasonal vaccine market.

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Opinion: Diversity statements should not be required for federal STEMM grant funding

STAT

Federally funded research in science, technology, engineering, mathematics, and medicine (STEMM) is a crown jewel of American higher education that confers enormous benefits upon the U.S. and the world. The integrity of the processes by which funding decisions are made is critically important to the success of the enterprise and its support by the public who pay for this research.

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The infectious disease doctor shortage will hit marginalized people the hardest

STAT

The Covid-19 pandemic underscored the importance of infectious disease doctors — but the field is still facing a shortage , with consequences for the health of communities across the U.S. Specialists spoke out about the impact of the shortage and potential solutions at a recent press briefing organized by the Infectious Diseases Society of America.

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Study: How mRNA-1345 RSV Vaccine Compares to Previously Approved RSV Vaccines

Pharmacy Times

The mRNA-1345 vaccine provides a one-off mechanism of protection because of its single-dose prefilled syringes

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Millions of people became uninsured as Medicaid programs cut coverage, new data show

STAT

The national uninsured rate rose from 7.7% to 8.2% earlier this year, a result of states booting millions of Americans from their state Medicaid programs, according to new data from the Centers for Disease Control and Prevention. The 7.7% uninsured rate in 2023 was a record low at the time, but didn’t factor in any of the people who were losing their Medicaid coverage.

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Research Suggests Alzheimer Disease and Periodontal Disease Are Linked by Inflammation

Pharmacy Times

Periodontitis and AD are both characterized by inflammatory and immunological response by the host.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Opinion: Phasing out the ‘D-word’

STAT

As I roamed the meeting rooms and halls of the Alzheimer’s Association International Conference in Philadelphia last week, I kept hearing a word — dementia — I’ve come to loathe as someone with early Alzheimer’s. The use of this term goes back as far as the late 1500s, when it referred to insanity. It’s an inaccurate, outdated, and stigmatizing term that I and others living with cognitive impairment want to see retired permanently.

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Tumor-Treating Fields Boost Natural Killer Cell Cytotoxicity in Glioblastoma

Pharmacy Times

The findings highlight the potential for developing more efficacious combination treatments for patients with glioblastoma.

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More heart patients getting prompt post-hospital care, but disparities increase

STAT

Recovery from a cardiac-related hospitalization requires coordinated, timely care to prevent a return to the hospital for an avoidable readmission. A new study concludes that while the picture is getting brighter for all Medicare patients, persistent racial disparities are widening. Poorer and rural patients were also less likely to have prompt post-discharge visits to check on issues such as medication, a common contributor to readmission.

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Bristol Myers telegraphs layoffs in New Jersey, trimming 117 jobs in staggered wave of cuts

Fierce Pharma

Bristol Myers Squibb, while working its way through a major restructuring, has unveiled another round of layoffs in New Jersey. | Bristol Myers Squibb, while working its way through a major restructuring, has unveiled another round of layoffs in its home state of New Jersey.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: BioMarin to restrict sales of hemophilia gene therapy, seeking to overcome slow sales

STAT

Struggling to find new patients, BioMarin Pharmaceuticals on Monday said it would restrict sales of its gene therapy for hemophilia A to three countries where it is currently approved, including the United States — a restructuring intended to reduce costs and help the treatment become profitable by next year. The one-time treatment called Roctavian was approved in Europe in 2022 and in the U.S. in 2023.

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Patient Satisfaction with Mail-Order Pharmacies Increases, but Shrinks for Chain Stores

Drug Topics

J.D. Power and Associates released a report detailing the change in mail-order and retail pharmacy trends from 2023 to 2024.

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uniQure wields axe again as Huntington's therapy progresses

pharmaphorum

uniQure sheds two-thirds of its staff as it refocuses around a leaner pipeline headed by Huntington's therapy AMT-130

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Opinion: Cost-effectiveness of health interventions may be perpetuating health disparities. Here’s how to fix that

STAT

As an epidemiologist and physician, I’ve long been concerned about how health interventions for marginalized communities are evaluated. A new study explores that concern and offers some solutions for making cost-effectiveness analyses work for everyone. Many of my patients live in San Francisco’s Bayview neighborhood, which is disproportionately Black, cut off from the rest of the city by freeways, and has a toxic waste problem from a nearby shipyard.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Tenet to sell 5 Alabama hospitals to Orlando Health in $910M deal

Fierce Healthcare

Tenet Healthcare will sell off five Alabama hospitals to Orlando Health in a $910 million cash deal. | Tenet Healthcare will sell off five Alabama hospitals to Orlando Health in a $910 million cash deal.

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How to harmonise global content strategies with local needs in the pharmaceutical market

pharmaphorum

Learn how to effectively harmonise global content strategies with local needs in the pharmaceutical market. Understand the unique challenges in the life science industry and how to measure success with relevant KPIs.

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In July, PBMs Found Themselves in the Federal Government Hot Seat

Drug Topics

An interim FTC report outlined how the rise of vertical integration and concentration has led to devastating results for both patients and fragile pieces of the health care delivery system.

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Exploring the role of pharmacy and self-care in the fight against fatty liver and disease progression

pharmaphorum

Exploring the role of pharmacy and self-care in the fight against fatty liver and disease progression Mike.

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Johnson & Johnson’s MedTech announce orthopaedics receives 501K clearance from FDA for spinal robotics and navigation platform

Pharmafile

Today, the Orthopaedics branch of Johnson & Johnson MedTech, DePuy Synthes, has announced that their surgical robotics system VELYS active has received 501k clearance from the US Food and Drug Administration (FDA). The post Johnson & Johnson’s MedTech announce orthopaedics receives 501K clearance from FDA for spinal robotics and navigation platform appeared first on Pharmafile.

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Bayer's Kerendia passes key test, cutting risk of cardio death and heart failure

Fierce Pharma

Bayer’s Kerendia was approved in 2021 to treat patients with chronic kidney disease (CKD) associated with Type 2 diabetes. | In a phase 3 trial, Bayer's Kerendia has shown it can reduce the risk of cardiovascular death, as well as first and recurrent heart failure events, in HF patients with mildly reduced or preserved ejection fraction.

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FDA ad comm favors Zevra’s Niemann-Pick drug

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Morning! Today, we discuss the maneuverings of two interesting women in biotech: Verily alum Amy Abernethy and 23andMe CEO Anne Wojcicki. Also, we explore the dangers of off-brand GLP-1s, and see FDA advisers vote in favor of a Niemann-Pick drug.

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Changing Faces May-June 2024: Agency, consultancy, and investor

pharmaphorum

Discover the latest updates and insights on Agency, Consultancy, and Investor trends in the Changing Faces May-June 2024 issue featuring key players like Hanover, Real Chemistry, EVERSANA, Box Bear, and more.

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Can you eat cherries if you have diabetes?

The Checkup by Singlecare

If you have Type 2 diabetes, your diet can play a significant role in managing the condition. That’s because what you eat directly impacts your blood sugar levels and your overall health. A balanced diabetes diet should include a variety of nutrient-dense foods, such as fruits, vegetables, lean proteins, whole grains, and healthy fats. Counting carbohydrates, exercising portion control, and limiting processed, sugary, and fatty foods are important ways to keep your blood glucose levels in a heal

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EC grants orphan drug status for Amylyx’s Wolfram treatment

Pharmaceutical Technology

The European Commission (EC) has granted orphan drug designation (ODD) for Amylyx Pharmaceuticals’ AMX0035 to treat Wolfram syndrome.

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As Krystal's Vyjuvek gains momentum, analysts spotlight 'transition point' in topical gene therapy launch

Fierce Pharma

Following a launch last summer, Krystal Biotech’s topical gene therapy Vyjuvek is continuing to make waves in the dystrophic epidermolysis bullosa (DEB) disease space. | The quarter marks a “transition point” in Vyjuvek’s launch, analysts at Evercore ISI wrote in a note to clients. While the analysts expect the drug's sales to keep growing, they cautioned of a potential slowdown in the third quarter and beyond as Krystal's initial commercial efforts shift to patient identification effo

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STAT+: Pharmalittle: We’re reading about MDMA trials, weight loss drug availability, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was invigorating and refreshing, because that oh-so familiar routine of online meetings, phone calls, and deadlines has returned. But you knew this would happen, yes? After all, the world, such as it is, continues to spin, albeit a bit wobbly at times. So perhaps we should give it a nudge in a better direction with a cup or three of stimulation.

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DEA Fines Ambulatory Surgery Center for Controlled Substance Violations. Could you be next?

OctariusRx

An ambulatory surgery center (ASC) in Iowa recently agreed to pay $125,000 to settle allegations that it violated the Controlled Substances Act. How is your facility managing controlled substances? Do you have systems in place to ensure proper ordering, receiving, storage, administration and disposal? How sure are you that your policies are compliant?

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Discover Breakthrough Pharma Marketing Strategies at Digital Pharma East 2024

Fierce Pharma

The pharmaceutical industry is in a constant state of evolution, driven by technological advancements, shifting consumer behaviors, and a complex regulatory landscape. | Join us at Digital Pharma East 2024 on Sept. 9-12 in Philadelphia to learn, connect, and innovate with your life sciences marketing industry peers.

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Bayer's finerenone clears key heart failure trial

pharmaphorum

At the start of this year, Bayer said there were two important trial readouts for the company to deliver near-term growth this year as it rebuilds its pipeline – and both have now delivered positive results in the space of a month.This morning, the German group revealed that mineralocorticoid receptor antagonist (MRA) Kerendia (finerenone) was able to reduce cardiovascular death and other heart failure events compared to placebo in the FINEARTS-HF trial.

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