Fri.Nov 17, 2023

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Women With Endometriosis More Likely to Experience Mental Health, Menstrual, Pain Symptoms

Drug Topics

Women with endometriosis face an average of 7 to 11 years between the time of symptom onset and diagnosis, during which they experience increased symptoms, hospitalizations, and health care resource utilization.

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New Blood-Based Rapid Test Can Simultaneously Detect HIV, TB

Pharmacy Times

Not only is the test significant for identifying HIV and TB, but it can be safer for patients living with HIV due to their suppressed immune systems.

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Trending Sources

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Flu season is approaching, CDC says

STAT

Flu activity in many parts of the United States is starting to rise more rapidly, signaling that flu season is on the horizon, the Centers for Disease Control and Prevention reported Friday. With Americans set to travel for Thanksgiving gatherings next week, people who’ve been waiting to get a flu shot should think about acting now, Alicia Budd, the CDC’s team lead for domestic flu surveillance, told STAT.

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Addressing Burnout: Understanding the Root Causes in the Workplace

Pharmacy Times

In this multi-part series on burnout and the problems currently facing pharmacy, trauma-informed pharmacist Helen Sairany, PharmD, MBA, discusses why burnout is skyrocketing.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: Even as Wegovy rides high, interest surges in weight loss drugs that preserve muscle

STAT

Have you ever seen a mouse with a set of muscles more appropriate for a bodybuilder or comic book superhero? Well, 25 years ago, researchers at Johns Hopkins University made it happen. By silencing a gene responsible for producing a protein called myostatin, they directed tiny mouse bodies to grow double the amount of lean muscle they would normally, leading to mice with bulky arms, defined pectorals, and an overall more substantial body mass.

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Expert Discusses Investigational AVB-101 for Frontotemporal Dementia

Pharmacy Times

Lisa Deschamps, CEO of AviadoBio, discusses frontotemporal dementia and AVB-101, a one-time therapy designed to stop disease progression by delivering a functional copy of the GRN gene and restoring progranulin levels in the brain.

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More Trending

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US patients believe generative AI can improve healthcare access, affordability, survey finds

Fierce Healthcare

As the industry continues to debate the promise and risks of artificial intelligence in healthcare, patients are bullish on the potential for generative AI to improve access and even lower healthca | As the industry continues to debate the promise and risks of artificial intelligence in healthcare, patients are bullish on the potential for generative AI to improve access and even lower healthcare costs.

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STAT+: FDA approves Medtronic high blood pressure device despite a negative advisory panel vote

STAT

The Food and Drug Administration has approved a Medtronic device to lower blood pressure, the company announced Friday evening. The decision comes after an advisory panel narrowly voted against the device in August. The FDA approved a similar product, part of a device class called renal denervation, from startup Recor Medical earlier this month. “Medtronic has always believed in the potential of this therapy,” Jason Weidman, renal denervation head at Medtronic, said in a statement.

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Confusion Persists Around the Interchangeability Designation for Biosimilars

Pharmacy Times

The legal and common uses of “interchangeability” continue to be conflated.

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STAT+: Doctors divide over reforming a secretive panel that determines their Medicare pay

STAT

WASHINGTON — Doctors are splitting, specialty by specialty, over whether and how to overhaul a secretive panel that helps determine how much Medicare pays them for their work. Doctors who get paid more by Medicare generally like the way the panel operates now. But doctors who are paid relatively less are looking for ways they say would make the process more fair.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA signs off on new uses for Astellas and Pfizer's Xtandi, Merck's Keytruda

Fierce Pharma

The FDA has signed off on label expansions for two of the world’s most important cancer medicines—Merck’s Keytruda and Pfizer and Astellas’ Xtandi. | The FDA has signed off on label expansions for two of the world’s most important cancer medicines—Merck’s Keytruda and Pfizer and Astellas’ Xtandi. Keytruda’s expansion is in stomach cancer. Xtandi’s new indication expands its already deep portfolio in the treatment of prostate cancer.

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STAT+: A digital pill shows early promise in detecting opioid overdose, sleep apnea

STAT

Gathering health data remotely is a pain. Forgetting to slip on a wearable is easy, and hooking yourself up to a large monitor is intrusive. Celero Systems has another idea: What if your remote patient monitor was small enough to swallow? A team of researchers has tested Celero’s device in humans for the first time, successfully capturing heart and respiratory data in 10 patients with sleep apnea.

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Civil rights groups deal failing grades to states on Medicaid disenrollments

Fierce Healthcare

A coalition including the NAACP and other civil rights organizations released a scorecard Thursday grading each state on its policies handling the Medicaid unwinding period. | Just one state received a passing score on Medicaid redeterminations from a coalition of nationally recognized civil rights groups.

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Frontiers Health 2023: Hakim Yadi, Closed Loop Medicine

pharmaphorum

Frontiers Health 2023: Hakim Yadi, Closed Loop Medicine Mike.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT+: Biden appoints Vanderbilt oncologist to head National Cancer Institute

STAT

WASHINGTON — President Biden on Friday said he plans to appoint cancer researcher and doctor Kimryn Rathmell to lead the National Cancer Institute. Rathmell will assume leadership of the $7.3 billion agency amid the administration’s efforts to relaunch Biden’s Cancer Moonshot initiative with an emphasis on screening, prevention, and better treatment.

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FTC blocks Tenet Healthcare, John Muir Health's California hospital deal

Fierce Healthcare

The Federal Trade Commission (FTC) has stepped in to block a California hospital deal it said will result in less competition and higher healthcare costs. | A federal and state investigation concluded that the deal for San Ramon Regional Medical Center would give John Muir Health over 50% of the local inpatient general acute care market, likely leading to higher prices and lower quality in the area.

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AstraZeneca plans to exit 'beating heart' of Indian operations in Bangalore

Fierce Pharma

Amid a corporate review of AstraZeneca’s global manufacturing and supply network, the company’s Indian subsidiary is planning to close up shop at the “beating heart” of its India operations in Bang | AstraZeneca Pharma India will exit its production plant in Bangalore, India, “in due course,” the company said in a filing. AZ plans to find a buyer who can also serve as a contract manufacturer for the drugs produced there.

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FDA Accepts Priority Review Application for Lisocabtagene Maraleucel for Relapsed or Refractory CLL, SLL

Pharmacy Times

The acceptance comes after results from TRANSCEND CLL 004, which is the first trial to demonstrate clinical benefit with a CAR T cell therapy in patients who were previously treated for CLL or SLL.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Opinion: We tried to quantify how harmful hospital ransomware attacks are for patients. Here’s what we found

STAT

This article is part of a partnership between First Opinion and Tradeoffs, a nonprofit news organization exploring our confusing, costly, and often counterintuitive health care system. To learn more about how ransomware hurts hospitals and patients, listen to a  deeper dive  from Tradeoffs, and  subscribe  to never miss an episode.

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Zonisamide Clinical Update and Literature Review

Drug Topics

Zonisamide has a role in the treatment of epilepsy and is being explored in other central nervous system disorders.

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FDA Approves Pembrolizumab Plus Chemotherapy to Treat Metastatic HER2-Negative Gastric, Gastroesophageal Junction Adenocarcinoma

Pharmacy Times

The approval makes pembrolizumab the first-line treatment for individuals with this cancer.

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AstraZeneca’s first-in-class FDA approval for Truqap marred by surprise restriction

Fierce Pharma

After the landmark success of Enhertu in HER2-low breast cancer, AstraZeneca has blazed another trail in the world’s most common cancer type. | After the landmark success of Enhertu in HER2-low breast cancer, AstraZeneca has blazed another trail in the world’s most common cancer type. But an unexpected restriction has cast a dark cloud over the first-in-class approval.

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Generic Product News - November 2023

Pharmacy Times

The products include Doxycycline Hyclate Delayed-Release Tablets, Lisdexamfetamine Dimesylate Capsules, Calcium Gluconate in Sodium Chloride Injection, Estradiol Tablets USP

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ABPI says UK clinical trials sector ‘improving’

pharmaphorum

ABPI says UK clinical trials sector ‘improving’ Phil.

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Tenet Healthcare selling 3 South Carolina hospitals to Novant Health for $2.4B cash

Fierce Healthcare

Tenet Healthcare has cut a deal with Novant Health to sell off three South Carolina hospitals and their related operations for roughly $2.4 billion, the systems announced Friday morning. | The deal leaves Tenet with after-tax proceeds of $1.75 billion, which it said it will primarily use for debt retirement. The systems said they'll remain partners for ambulatory surgery and revenue cycle management in the affected markets.

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??A startling drop in U.S. life expectancy — and how pharma could help turn the tide

PharmaVoice

The recently observed dip was particularly acute for men, who now live an average of 5.8 fewer years than women.

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Digital health company BehaVR hits the merger trail again

pharmaphorum

Digital health company BehaVR hits the merger trail again Phil.

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DSN’s Top Women in Health, Wellness & Beauty 2023 award winners

Drug Store News

Drug Store News celebrates the women making their mark in retail pharmacy with the fifth annual awards program.

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FDA’s Janet Woodcock will step down early next year

pharmaphorum

FDA’s Janet Woodcock will step down early next year Phil.

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STAT+: Pharmalittle: Woodcock to retire from the FDA; Acrotech urged to speed up confirmatory study of cancer drugs

STAT

And so, another working week will soon draw to a close Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest. Besides the usual promenading with the official mascots, we hope to catch up on our reading and manicure the Pharmalot grounds. We may also have time for a listening party with a rotation that would likely include this , this , this , and this.

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Modernising clinical trials: The PARTICIPATE framework

pharmaphorum

Modernising clinical trials: The PARTICIPATE framework Mike.

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Micron Biomedical receives funds to produce needle-free vaccines

Pharmaceutical Technology

Micron Biomedical has received $23.6m in funding from the Bill & Melinda Gates Foundation for the bulk manufacturing of needle-free vaccines.

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Q&A With Jade Shields, Vice President of Corporate Affairs at Ferring Pharmaceuticals

PharmExec

Shields discusses Ferring’s recent $5 million endowment to the American Society of Reproductive Medicine.

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