Wed.Dec 27, 2023

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Quitting alcohol — or even drinking less — reduces risk of oral cavity and esophageal cancer, per new analysis

STAT

Reducing or eliminating alcohol consumption reduces the risk of developing oral cavity and esophagus cancers, according to a special report from the International Agency for Research on Cancer. But more data are needed to conclude whether the same is true for several other cancer types, including colorectal, breast, and liver cancer. Even so, it is likely that reducing or ceasing to drink alcohol will lessen the risk of these cancers, said Farhad Islami, a cancer epidemiologist at the American C

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Adverse events increased after hospitals acquired by private equity, study finds

Fierce Healthcare

A hospital’s acquisition by a private equity firm is linked to a rise in adverse events despite the pool of lower risk patients they tend to admit, according to a Medicare Part A claims analysis pu | Hospital-acquired adverse events among Medicare beneficiaries were 25% higher within the three years after a private equity acquisition compared to control hospitals, researchers found when reviewing millions of Part A claims.

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Opinion: Remembering Betty Rollin, who told her breast surgeon that post-operative appearance mattered to her—and other women

STAT

Women who had undergone disfiguring surgery for breast cancer, according to one surgeon in the 1970s, needed to “stick an old sock in their bra and get on with their lives.” It was this climate that Betty Rollin, then a television correspondent for NBC, entered when she was diagnosed with the disease in 1975. Rollin, who died of voluntary assisted suicide in Switzerland in November at age 87, became a highly visible activist not only for women with breast cancer but also end-of-lif

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Amgen's request for full approval of Lumakras in lung cancer denied by FDA

Fierce Pharma

Amgen’s request to gain full approval of Lumakras in non-small cell lung cancer has been rejected by the FDA. | Amgen’s request to gain full approval of Lumakras in non-small cell lung cancer has been rejected by the FDA. The California biopharma will now have to conduct an additional confirmatory trial to gain the coveted FDA nod.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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STAT+: Cytokinetics heart drug aficamten succeeds in pivotal study

STAT

An experimental medicine from Cytokinetics significantly improved exercise capacity for patients with a rare, progressive heart disease, the company said Wednesday — a result that compared favorably with a competing treatment from Bristol Myers Squibb. The study enrolled about 300 people with obstructive hypertrophic cardiomyopathy, or HCM, a hereditary disorder that restricts blood flow.

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BMS strikes again, with $4.1bn RayzeBio takeover bid

pharmaphorum

Bristol-Myers Squibb makes a foray into the radiopharmaceutical category with a $4.

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Pfizer's Hospira recall spree bleeds into 2024 with product pulls for multiple hospital drugs in shortage

Fierce Pharma

After a year plagued by recalls, Pfizer’s sterile injectables unit Hospira seems no closer to righting the ship over its glass-contamination woes. | After a year plagued by recalls, Pfizer’s sterile injectables unit Hospira seems no closer to righting the ship over its glass-contamination woes. Shortly before the holiday, Hospira announced two separate recalls over the potential presence of glass particulates in vials and syringes of certain hospital meds.

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Opinion: People with food insecurity deserve better nutrition education

STAT

Since spring 2022, a flood of migrants fleeing political instability in Venezuela — about 136,000 — have settled in Queens, New York, and are in desperate need of food and other resources. The surging migrant population has led to depleted food pantries in the borough; as of June 2023, more than 20.5% of Queens residents are experiencing food insecurity.

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Insulin Storage and Beyond Use Dates – Free Downloadable PDF

Med Ed 101

We’ve taken the time to create a new free PDF resource. In my practice, I always run into nursing staff and caregivers who are using expired insulin or who are not dating the insulins that are in use. Insulin Storage and Beyond Use Dates Free PDF should be a vital resource designed to help healthcare […] The post Insulin Storage and Beyond Use Dates – Free Downloadable PDF appeared first on Med Ed 101.

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Violet CEO on measuring clinician inclusiveness: ‘It’s almost like a credit score’

STAT

PHOENIX, Ariz. — Gaurang Choksi is the founder and CEO of Violet , a health equity platform that aims to standardize and increase cultural competence among clinicians. The New York-based startup provides inclusivity training for clinicians in order to help promote identity-centered health care, particularly for patients who typically face greater barriers to receiving quality care because of their race, ethnic or gender identity.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Developing point-of-care CAR T manufacturing

European Pharmaceutical Review

Chimeric antigen receptor (CAR) T cells are the first example of a “living drug”. 1 Following in vitro production from T cells collected from a patient’s leukapheresis procedure, the CAR T cells are infused back into the patient’s blood, where they proliferate and expand. The CAR T cells need to persist in the blood to expand and elicit maximal effect, and there is a correlation between expansion and persistence and response.

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STAT+: 3 issues to watch in pharma in 2024

STAT

As another year comes to an end and the world seems to hit the proverbial pause button, the temptation to look ahead is too great to ignore. After all, this is what journalists like to do as the calendar turns another page. So once again, we will take a whack at identifying some of the most noteworthy developments to watch. However, if these seem familiar, there is good reason.

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Top Marketing Stories of 2023

PharmExec

Pharma marketing teams had to deal with big changes in 2023.

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STAT+: 3 FDA staffers to watch in 2024

STAT

WASHINGTON — The Food and Drug Administration has a lot on its plate in 2024 with the reorganizations of its food center and the office that inspects FDA-regulated facilities. Amid that massive reorganization, the FDA also will lose one of its most influential leaders. Janet Woodcock is retiring at the beginning of the year after decades of service.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AstraZeneca buys Chinese CAR-T biotech Gracell in a $1.2bn deal

Pharmaceutical Technology

The deal is worth approximately $1.2bn in combined upfront and potential contingent value payments and is expected to close in Q1 2024.

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STAT+: What comes after Wegovy? The quest to eradicate obesity

STAT

About a decade ago, after becoming obese, Jacob Petersen lost weight so quickly that some colleagues worried he might have cancer. Petersen, who was then the head of global metabolic research at Novo Nordisk, hadn’t turned to his company’s famed medicines like Ozempic and Wegovy — the wildly effective drugs didn’t exist yet.

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Looking to the future of UK medical device exports

pharmaphorum

In this second of our festive podcast series, the pharmaphorum podcast welcomed Brandon Medical CEO Keith Jackson and the Association of British HealthTech Industries (or ABHI) director of communications, Jonathan Evans, to discuss UK medical device exports, including a particular recent strategic APAC partnership and the general and ongoing representation of industry innovation to stakeholders including government, NHS, and regulators.

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Cabinet Health debuts in select Target locations

Drug Store News

Target shoppers can now purchase 14 SKUs of Cabinet Health medications, including Allergy Relief, Pain Relief, Digestive Care and Cold & Flu Relief.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Eligibility Factors in Multiple Myeloma Transplant

Pharmacy Times

Gabriel Hinojosa, PharmD, BCOP, analyzes eligibility factors and treatment shifts in multiple myeloma care, considering autologous stem cell transplant risks and evolving therapy approaches with daratumumab.

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Update: Apple Watches back on sale after appeal

pharmaphorum

Apple will appeal a decision by the USTR not to veto a ban on US imports of some of its smartwatches, found to violate patents held by wearables company Masimo

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Top 5 Pharmacy Times Skin Cancer Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read skin cancer-related articles on Pharmacy Times in 2023.

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The rapidly evolving role of patient organisations

pharmaphorum

Patient organisations play a crucial role in the rapidly evolving landscape of healthcare, life sciences, and research. Learn about their role in advocacy, research, and navigating regulatory processes in this informative article.

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Top 5 Pharmacy Times Reimbursement Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read reimbursement-related articles on Pharmacy Times in 2023.

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Hikma intros phenylephrine HCl Injection

Drug Store News

Phenylephrine HCl Injection is indicated for increasing blood pressure in adults with hypotension resulting primarily from vasodilation in the setting of anesthesia.

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Top 5 Pharmacy Times Pneumococcal Articles of 2023

Pharmacy Times

From newsworthy moments to groundbreaking research, these were the most-read pneumococcal-related articles on Pharmacy Times in 2023.

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Teva intros generic Forteo

Drug Store News

Generic Forteo is used to treat men and women with certain types of osteoporosis.

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8 of the best natural appetite suppressants

The Checkup by Singlecare

The prevalence of overweight and obese individuals continues to have a huge impact on the health of our population. Being overweight is associated with an increased risk of diabetes, heart disease, and other physical ailments. This leads us to always be on the lookout for products and methods that may help in the weight loss journey or healthy weight control.

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Eos debuts ‘Lotion Lock’ campaign

Drug Store News

The campaign highlights its humorous Lotion Lock and pokes fun at the in-demand virality of the lotion.

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What causes headache in the morning? Related conditions and treatments

The Checkup by Singlecare

Waking up with a splitting headache is not a great way to start the day. And a poor night’s sleep may be the cause. Understanding what’s interrupting your sleep is the key to preventing sleep-related headaches in the morning. Dehydration, caffeine, sinus congestion, and allergies are among some of the other causes of headaches in the morning. Relationship between sleep and headaches “Headaches and sleep problems share several brain pathways, particularly in the region of the hypothalamus,” says

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Our Top 5 Podcast Episodes of 2023

PharmExec

Our top five episodes of the year.

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Can you take Fioricet for migraines?

The Checkup by Singlecare

Migraines can be debilitating, and they affect more than 1 billion people globally. They have no cure, but they can be managed with the right medications. Fioricet ( butalbital-APAP-caffeine ) is a combination medication used to treat tension headaches, but it may also be prescribed for migraines. It is a mix of three different drugs: butalbital, acetaminophen (APAP), and caffeine.

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European Medicines Regulatory Network on Track to Meet Goals

BioPharm

The midterm report of the European Medicines Agencies Network Strategy finds that the network has strengthened and is on track to achieve its objectives.

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Wellbutrin XL side effects and how to avoid them

The Checkup by Singlecare

Common Wellbutrin XL side effects | Serious side effects | Weight loss | Side effects timeline | Interactions | Safety measures | How to avoid side effects | How to treat side effects Wellbutrin XL is a brand-name antidepressant taken as an extended-release tablet to treat symptoms of depression. The generic version of Wellbutrin XL is bupropion hydrochloride (HCl) extended-release (ER).

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