Mon.Jul 01, 2024

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Is LTC Pharmacy Going Back to the Future?

Drug Topics

Drug Topics sat down with Sandra Canally, RN, founder and CEO of The Compliance Team, and Kara Benson, PharmD, long-term care director of Lewis Drug Inc, to discuss the future of LTC pharmacy.

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Opinion: Psychiatrists aren’t fulfilling the social contract that subsidized their training

STAT

There has been much handwringing about how difficult it is for Americans with mental health issues to see a psychiatrist. Failures in the health insurance market are often blamed for the problem. As a new class of psychiatry residents begins work in hospitals across the country this week, I see an additional cause: the lack of commitment to honor the subsidies that made it possible for psychiatrists to enter the profession.

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Trending Sources

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Continuous Glucose Monitors Help Reduce A1c in Patients with Diabetes

Drug Topics

Research presented at the American Diabetes Association 84th Scientific Sessions suggests a population approach to CGM use could be beneficial.

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Steward Health Care spent millions spying on critics amid failing finances: report

Fierce Healthcare

As its stack of unpaid vendor obligations climbed, now-bankrupt Steward Health Care paid private investigators millions of dollars to follow and uncover compromising information on individuals | An investigative report details a "spare no expenses mission" in which executives authorized intelligence firms to allegedly follow, data mine and disseminate damaging information about individuals viewed as opponents.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Bird flu snapshot: A pathologist sees familiar echoes in U.S. response to the outbreak

STAT

Bird flu snapshot: This is the latest installment in a series of regular updates on H5N1 avian flu that STAT is publishing on Monday mornings. To read future updates you can also subscribe to STAT’s Morning Rounds newsletter. When pathologist Thijs Kuiken looks at what’s happening in the U.S. response to the H5N1 bird flu outbreak in dairy cows, he’s reminded of a difficult period in the Netherlands, where he lives, back in the late aughts.

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Digital primary care startup K Health raises $50M in equity funding round

Fierce Healthcare

Digital primary care startup K Health raised $50 million in an equity funding round to build out its AI-powered medical services and fuel its growth, the company announced Monday. | Digital primary care startup K Health raised $50 million in an equity funding round to build out its AI-powered medical services and fuel its growth, the company announced Monday.

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More Trending

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DOJ slaps $20M opioid prescription penalty on OptumRx

Fierce Healthcare

OptumRx will pay $20 million to resolve claims the company violated the Controlled Substances Act by improperly filling certain opioid prescriptions, the Department of Justice recently announced.

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Breaking Down Return Solutions’ Rx Returns Process with Jeremy Cundiff

Drug Topics

Jeremy Cundiff, PharmD, co-owner of Professional Pharmacy Group, joined Drug Topics to discuss Return Solutions and the company’s Rx Returns process.

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STAT+: Novel amputation procedure makes walking with a prosthetic leg feel more seamless

STAT

A novel surgical technique could dramatically improve walking for people with below-the-knee amputations and help them better control their prosthetics. A study published Monday in Nature Medicine showed that trial participants who received the procedure could walk faster, were more stable on uneven terrain, and had an increased spatial awareness, or proprioception, in their residual limb.

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FDA Approves Ustekinumab-ttwe as Biosimilar to Stelara

Pharmacy Times

Ustekinumab-ttwe (Pyzchiva; Sandoz) is approved for all indications of Stelara.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AstraZeneca files rival to Pemgarda for COVID PrEP

pharmaphorum

AstraZeneca may have exited the COVID-19 vaccine market, but it is still hoping to protect vulnerable patients with its antibody sipavibart for pre-exposure prophylaxis (PrEP).The drugmaker said this morning that an application for sipavibart (AZD3152) has been accepted for review by the EMA as PrEP for immunocompromised patients who often do not respond adequately to vaccination alone and remain at high risk of serious outcomes from COVID-19.

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Microbiome composition varies based on sampling time, mouse study finds

STAT

The microbiome has immense power to shape health outcomes. The bacteria that take up residence in the human body, including the gut, have been shown to impact health and disease, including neurodegenerative disorders. Medical research is invested in finding ways to reconstruct healthy microbiomes to help cure some of those ills.  But like many fields in science , microbiome research is suffering from a reproducibility crisis.

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Who should not take quercetin?

The Checkup by Singlecare

Quercetin is a flavonoid, a compound that gives plants—including fruits, vegetables, herbs, and flowers—their color. It’s found in many common foods and drinks, such as citrus fruit, apples, onions, buckwheat, cherries, berries, broccoli, red wine, green tea, parsley, sage, dill, and coriander. It’s also available as a supplement. If you’ve noticed it in grocery and drug store aisles recently, it may be because this dietary antioxidant is becoming more popular.

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STAT+: After months of warnings, FTC opens investigation into Teva over ‘improper’ patents

STAT

The Federal Trade Commission is formally investigating Teva Pharmaceuticals after the company refused to remove approximately two dozen patents for asthma and COPD inhalers from a key federal registry. The agency sent a civil investigative demand requiring Teva to provide information related to the patents listed in the so-called Orange Book, which is maintained by the Food and Drug Administration.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Why informed patient consent is vital for successful clinical trials

pharmaphorum

Informed patient consent is crucial for the success of clinical trials. Learn about the importance of consent in clinical trials and how it impacts the outcomes.

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Perinatal Depression May Increase Risk of Cardiovascular Disease in Women

Pharmacy Times

Perinatal depression increases the risk of cardiovascular disease in women.

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Lilly builds in radiopharma with $140m Radionetics deal

pharmaphorum

Eli Lilly has lined up another deal in the radiopharmaceutical sector, paying $140 million to partner drugs developed by Radionetics Oncology and taking an option on buying the company outright for $1 billion.Radionetics is working on small-molecule drugs that target G protein-coupled receptors (GPCRs), a fertile source of drug targets for the pharma industry and the target of around a third of all marketed drugs but according to the company is a “largely unexplored” class for radiopharma.

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Ongoing Phase 3 LINKER-MM3 Trial Assesses Safety and Efficacy of Linvoseltamab Monotherapy in Patients With RRMM

Pharmacy Times

The monotherapy is compared with the combination regimen of elotuzumab plus pomalidomide and dexamethasone in adult patients with relapsed or refractory multiple myeloma.

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France agrees to fund experimental glioblastoma therapy

pharmaphorum

France's HAS agrees to fund treatment with Carthera's ultrasound device for French subjects enrolled in a glioblastoma trial.

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What’s Complicating Good Data Practices and Data Integrity?

Pharmacy Times

As the data management landscape continues to shift and change with AI and technological advancements all around us, it is essential to maintain good data practices and ensure data integrity in pharmaceutical research and development.

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Opinion: Medicare should wait on approving coverage for new obesity drugs

STAT

My dad, Randy, a 72-year-old retired sales manager, started to gain weight after grad school, and it didn’t let up until he was middle-aged. He’s now living with high blood pressure and high cholesterol. His cardiologist has told him, “You know, if you lost 15 pounds, you could get off your blood pressure medicine.

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After Gilead and J&J lawsuits, distributor Safe Chain sees its owners charged with wire fraud, conspiracy

Fierce Pharma

In yet another legal development surrounding counterfeit HIV drugs, a Florida court has handed down an indictment for the owners of a wholesale distributor that allegedly bought and redistribu | The wholesaler Safe Chain allegedly purchased $90 million of misbranded, diverted and adulterated HIV meds, according to U.S. authorities. The indictment of the company's three owners follows separate lawsuits from Gilead and Johnson & Johnson.

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NeuroSense says ALS drug extends survival

pharmaphorum

NeuroSense Tx reports 12-month data with its amyotrophic lateral sclerosis therapy PrimeC, including a 43% improvement in survival

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GSK takes another Zantac personal injury case off its plate with settlement in Illinois

Fierce Pharma

GSK scratched another Zantac lawsuit off the list with a confidential settlement in Illinois as it continues to work through the mountain of personal injury litigation related to the heartburn pill | Following a win and a separate dismissal in Illinois, GSK agreed to a confidential settlement to resolve prostate cancer claims put forward by plaintiff Martin Gross.

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CHMP meeting highlights – June 2024

European Pharmaceutical Review

At its recent June meeting, the EMA’s human medicines committee (CHMP) recommended 10 medicines for approval. Recommendations for regulatory approval The committee saw a need to give a marketing authorisation to Balversa (erdafitinib) as a treatment for adults with unresectable or metastatic urothelial carcinoma. In its meeting, the CHMP gave a positive opinion for the first nasally administered emergency treatment for allergic reactions.

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Talc claimants denied in effort to block Johnson & Johnson's latest Texas two-step bankruptcy

Fierce Pharma

Less than three weeks after a group of cancer victims filed a motion against Johnson & Johnson attempting to block the company’s latest bankruptcy plan—which comes with a $6.5 billion class-act | Less than three weeks after a group of cancer victims filed a motion attempting to block Johnson & Johnson's latest talc litigation bankruptcy plan—which comes with a $6.5 billion class-action settlement offer—a New Jersey federal court has quashed the effort.

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Babies of Mothers Prescribed GLP-1s Prior to Pregnancy May Have Increased Risk of NICU Stays

Pharmacy Times

Additionally, birth weight was higher in babies born to mothers who were prescribed glucagon-like peptide-1 (GLP-1) medications either 90 days prior to pregnancy or during the first trimester.

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Regulatory tracker: Sandoz, Samsung Bioepis gain FDA approval for biosimilar to J&J's Stelara

Fierce Pharma

Welcome to Fierce Pharma's regulatory tracker for the second half of 2024. | In this tracker, Fierce Pharma is recording the regulatory progress of in-market products, including expansions into key geographies and new indications. Some of these updates may not meet the bar for standalone stories, but we think they are still worth mentioning.

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FDA Grants Orphan Drug Designation to RCT1100 For Primary Ciliary Dyskinesia

Pharmacy Times

RCT1100 is designed to deliver DNAI1 mRNA directly to affected airways through an inhaled nebulizer and fills an urgent unmet need in the treatment of those with primary ciliary dyskinesia.

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As former BMS CEO Giovanni Caforio plots move to Novartis, will noncompete issues come into play?

Fierce Pharma

Fierce Pharma explored the status of the industry's noncompete clauses with experts to learn whether an intercompany transition at the highest levels can proceed without a hitch.

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STAT+: Pharmalittle: We’re reading about indicted drug wholesalers, a gene therapy rejection, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was relaxing and invigorating, because the familiar routine of online meetings, calls, and deadlines has predictably returned. But you know, the world — such as it is — continues to spin. So what can you do but try to give it a nudge in a better direction.

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Risk adjusted net present value: What is the current valuation of Pfizer’s Atirmociclib?

Pharmaceutical Technology

Atirmociclib is a small molecule commercialized by Pfizer, with a leading Phase III program in Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (HER2- Breast Cancer).

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Key Considerations for the Effective Utilization of RSV Vaccines

Pharmacy Times

Experts give important background information on respiratory syncytial virus (RSV), as well as the key clinical considerations that are associated with RSV vaccine use.

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The Rise Fund commits $200M to Foodsmart for telenutrition services

Fierce Healthcare

Leading telenutrition platform Foodsmart banked a $200 million investment from The Rise Fund, which backs entrepreneurs working to achieve the United Nations’ Sustainable Development Goals.

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