Fri.May 31, 2024

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Vaccination Prior to Initial Infection Reduced Risk of Post-COVID Condition

Drug Topics

Researchers addressed the association between COVID-19 vaccination status and incidents of post-COVID condition.

Vaccines 187
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NIH documents show how $1.6 billion long Covid initiative has failed so far to meet its goals

STAT

More than three years ago, the National Institutes of Health launched a $1 billion-plus initiative to find the root causes and potential treatments for long Covid , the chronic disease that has quickly changed the lives of millions of Americans. But a lack of visible progress from the initiative, called RECOVER, has drawn months of criticism from patient advocates, researchers, and lawmakers, including at a Senate hearing last week on the NIH’s budget.

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Podcast: How an Independent Pharmacist Incorporated Coffee into His Pharmacy

Drug Topics

In an interview with Chris Schaffner, PharmD, owner of Schaffner Pharmacy and Apothecary Coffee in Sedro-Woolley, Washington, he discussed his unique pharmacy operation with the help of coffee shop revenue.

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STAT+: For one rare type of lung cancer, Pfizer pill reduces progression by 81%

STAT

There are a lot of reasons why updated data on Pfizer’s Lorbrena, a treatment for non-small cell lung cancer, might not seem to be a big deal. The results are an update on the clinical trial that resulted in the Food and Drug Administration granting Lorbrena full approval in 2001, so in a sense they are not even that new. For Pfizer investors, Lorbrena isn’t that big a deal, either.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Over 30% of American Adults Know Someone Who Died of Drug Overdose

Drug Topics

According to a survey, 18.9% of respondents said that the person they knew who died of a drug overdose was a family member or close friend.

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Opinion: The Pandemic Treaty will succeed only with investment to build strong health systems

STAT

As the 77th World Health Assembly takes place this week, negotiations around the Pandemic Treaty are front and center of conversations. The treaty has been beset by delay and misinformation. The vested interests of pharmaceutical companies, lobbying groups, and conservative British broadcaster Nigel Farage bleating about “defending sovereignty” are threatening to derail the treaty process entirely.

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Opinion: Mothers in treatment for opioid use disorder shouldn’t also have to fight child protective services

STAT

Pregnant people and new mothers who are being treated for opioid addiction often have to fight to keep their children out of the hands of child protective services. But it’s a fight they shouldn’t have to face. They’re active in treatment. They’re not using illegal drugs. Yet child protective services (CPS) often take their babies away — not because they’re unfit mothers, but because they’re being judged on falsehoods.

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ASCO: In surprise, J&J's injectable Rybrevant extends lung cancer patients' lives versus intravenous version

Fierce Pharma

When companies introduce an injectable version of an intravenously infused drug, better convenience with comparable efficacy is typically the goal. | When companies introduce an injectable version of an intravenously infused drug, better convenience with comparable efficacy is typically the goal. But to Johnson & Johnson’s surprise, a subcutaneous formulation of its lung cancer med Rybrevant proved to work better than the original infusion.

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Once Weekly Efsitora Shows Non-Inferiority in A1c Reductions Compared With Daily Basal Insulin

Pharmacy Times

Topline results of QWINT-2 and QWINT-4 met the primary end point of change in hemoglobin A1c compared to degludec and glargine, respectively, for those with type 2 diabetes.

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Moderna gets FDA okay for RSV vaccine mResvia

pharmaphorum

Moderna has secured FDA approval for its RSV vaccine, setting up a three-way market battle with GSK and Pfizer.

Vaccines 119
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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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ESI Fees Violate Federal Policy; NCPA Pushes CMS for Clarity, Accountability

Pharmacy Times

Almost half of independent pharmacy owners/managers participating in an NCPA survey said that ESI was the pharmacy benefit manager causing the most financial stress in Medicare Part D.

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ASCO: Bristol Myers' confirmatory KRAS data avoid Amgen's flaws but still leave FDA prospects unclear

Fierce Pharma

After Amgen’s KRAS confirmatory trial results were rejected by the FDA as uninterpretable, Bristol Myers Squibb has divulged details of its rival study. | Bristol Myers Squibb has divulged the details of Krazati's confirmatory trial. While the study doesn't share the same design problems as Amgen's rival KRAS program, it still leaves open questions about Krazati's regulatory outlook.

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This week in clinical trials – 27th to 31st May

pharmaphorum

Stay updated with the latest clinical trials news from 27th to 31st May, featuring companies like Arcturus Therapeutics, AZ, Vesper Bio, Ultragenyx, and Incannex. Get insights into their latest developments and advancements in the field.

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Summit, Akeso's antibody triumphs over Keytruda in China lung cancer trial, sending shares skyrocketing

Fierce Pharma

Just one week after Summit Therapeutics and Akeso’s bispecific antibody ivonescimab passed muster with Chinese regulators, the drug has pulled off another feat by staring down the PD-1 king Keytrud | In the phase 3 HARMONi-2 trial, solo ivonescimab delivered a statistically significant and clinically meaningful improvement in progression-free survival over Keytruda monotherapy.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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ASCO: Novartis’ Scemblix aces first-line CML study

pharmaphorum

Novartis’ Scemblix could be headed for first-line use in chronic myeloid leukaemia after outperforming TKI drugs in the ASC4FIRST study presented at ASCO.

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Breaking: FDA Approves Moderna’s mRNA RSV Vaccine, mRESVIA

Drug Topics

mRESVIA is the first mRNA vaccine approved for a disease other than COVID-19.

Vaccines 112
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Gilead’s Trodelvy woes rise with failed bladder cancer trial

pharmaphorum

Gilead's TROP2 ADC Trodelvy has missed the target in another clinical trial, this time in urothelial carcinoma.

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Canadian Drug Importation May Do More Harm Than Good

Drug Topics

Authors analyzed Section 804 of the Food, Drug, and Cosmetic Act (FDCA) allowing state-sponsored programs to bring Canadian drugs onto US soil.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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BIO 2024: Enzene to Announce Drug Discovery Division

BioPharm

Enzene's new division will provide end-to-end integrated discovery services.

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FDA grants RMAT status for BlueRock’s Parkinson’s therapy

Pharmaceutical Technology

The US FDA has granted RMAT designation for BlueRock Therapeutics' cell therapy, bemdaneprocel (BRT-DA01), for Parkinson's disease.

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Pharma Pulse 5/31/24: Gen Z’s Passion for Skincare Falls Short on Sun Protection, A Long, But Promising Road Ahead in Clinical Trials & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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STAT+: Ionis drug prevents swelling attacks caused by rare genetic disease in late-stage trials

STAT

Ionis Pharmaceuticals, a California company that pioneered a whole class of RNA-targeted medicines, reported on Friday that a pair of late-stage trials showed that its experimental therapy for hereditary angioedema benefitted patients — including those taking drugs currently on the market. In one of the Phase 3 trials, dubbed OASIS, patients with hereditary angioedema, a rare disease characterized by severe bouts of swelling, were given injections of donidalorsen either monthly or every t

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FDA-Approved Self-Test for HPV: Another Tool in Fight to Eliminate Cervical Cancer

Drug Topics

Roche's self-collection kit allows women to screen for cervical cancer at home, offering an alternative to a visit to a healthcare provider and promoting early detection of the disease.

FDA 98
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Quadruple Therapies Including Immunotherapy Agents Show Benefit in Multiple Myeloma

Pharmacy Times

Quadruple therapies including immunotherapy agents show promise in treating patients with multiple myeloma.

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May Conference Roundup: AXS24, Digestive Disease Week

Drug Topics

Take a look back at the conference coverage you may have missed this month.

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How to stop night sweats

The Checkup by Singlecare

Is your sleep regularly disrupted by sweat-soaked pajamas or sheets from overheating? If so, night sweats may be to blame. The Mayo Clinic defines night sweats as repeated episodes of heavy sweating during sleep. Your perspiration may not be due to heat generated from thick bedding or a warm room. Instead, night sweats are usually caused by an underlying illness or medical condition.

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FDA Roundup: Drug Approvals From May 2024

Drug Topics

Check out these important FDA updates from the month of May 2024.

FDA 98
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Undercover Shoppers Experience Challenges in Accessing Legal, Clean OTC Needles in Arizona

Pharmacy Times

Study investigators hired undercover shoppers, and the results revealed more education is needed on the Syringe Service Program, which provides legal, clean over-the-counter (OTC) needles to whomever seeks them out.

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Dermatology Roundup: Skin Care in the Digital Age, The Gut-Skin Connection, and More

Drug Topics

Check out these can’t-miss dermatology stories published this month.

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Cannabis Use Can Exacerbate Cognitive Declines in Patients With Multiple Sclerosis

Pharmacy Times

Although this data seems to overwhelmingly suggest that cannabis use has negative impacts for individuals with multiple sclerosis (MS), listening to patients’ reasoning for using it is crucial.

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The Effect of Ransomware Attacks on US Hospitals and Adjacent Health Systems

Drug Topics

As health care technology advances and cyberattack threats loom large, researchers aimed to assess the effect of ransomware attacks on US health systems.

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FDA Grants Inavolisib Priority Review for Treatment of PIK3CA-Mutated Breast Cancer

Pharmacy Times

The priority review of inavolisib is for treatment of patients with advanced hormone receptor-positive, HER2-negative breast cancer with a PIK3CA mutation.

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Recap: Mental Health Awareness Month

Drug Topics

Check out a selection of our coverage from Mental Health Awareness Month.

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