Wed.Oct 30, 2024

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Meet the Specialty Pharmacist Championing HIV Care

Drug Topics

Cassandra Esperant, PharmD, AAHIVP, leverages her skills as a clinical pharmacist to champion the health of patients with HIV, both in her clinical practice and through education initiatives.

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STAT+: Novo Nordisk’s Ozempic and Wegovy, long in shortage, are now listed as available by FDA

STAT

All doses of Novo Nordisk’s blockbuster diabetes and obesity treatments are listed as available on the Food and Drug Administration’s drug shortage list as of Wednesday, raising the possibility that the medications could soon be taken off the list entirely, a development that could affect compounding pharmacies and patients relying on compounded drugs.

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Sublingual Epinephrine Film Promptly Resolves Symptoms in Patients With Oral Allergy Syndrome

Pharmacy Times

Results indicate that sublingual epinephrine can resolve symptoms, including swelling of the face and throat, associated with oral allergy syndrome in minutes.

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AI talk shifts from hype to 'rational exuberance,' healthcare execs say at HLTH 2024

Fierce Healthcare

At the HLTH 2024 conference in Las Vegas last week, attendees and exhibitors felt that the air had shifted around artificial intelligence. | The conversation around AI has shifted as health systems have begun to integrate operational solutions into their workflows.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Researchers Find “Digital Twin” Model Accurately Predicts Treatment Responses for Different Chemotherapy Drugs

Pharmacy Times

This model, which uses technology that discovers black holes, pulls from real data to evaluate cancer treatments, optimizing treatment choices for patients with different cancers.

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Humana updates guidance as it beats on revenue, profit in Q3

Fierce Healthcare

Humana updated its outlook for the year thanks to a Q3 where it beat the Street on both earnings and revenue. | Humana updated its outlook for the year thanks to a Q3 where it beat the Street on both earnings and revenue.

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GSK tries to steady the ship as Arexvy sales plummet in wake of CDC guidance changes

Fierce Pharma

To hear GSK CEO Emma Walmsley tell it, the third quarter presented “some challenges” for the drugmaker. | To hear GSK CEO Emma Walmsley tell it, the third quarter presented “some challenges” for the British drugmaker. For the company’s closely watched respiratory syncytial virus (RSV) vaccine Arexvy, those challenges led to drastically reduced sales.

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Public Concern of RSV Infection Has Decreased as Flu and COVID-19 Remain a Worry

Pharmacy Times

Findings suggest further need to educate the public on receiving an indicated vaccine as we approach peak respiratory syncytial virus (RSV) season.

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STAT’s 2024 Diversity and Inclusion Report

STAT

The STAT Diversity and Inclusion Committee presents STAT’s 2024 Diversity and Inclusion Report. Here, we share the self-reported gender and racial/ethnic demographics of our staff from STAT’s inception in 2015 through 2023, as well as our 2023 new hire demographics.  STAT’s Inaugural Diversity and Inclusion Report, published last year, is available here.

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Sage discontinues Zulresso, drops pair of pipeline prospects as it creeps toward 2026 cash cliff

Fierce Pharma

Ever since the FDA rejected zuranolone in major depressive disorder last year, brai | In the wake of a recent round of layoffs, the company this week revealed that it’s discontinuing a commercial medicine and giving up hopes for a pair of pipeline prospects.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Sales of GSK’s RSV vaccine down dramatically from last year

STAT

LONDON — GSK’s once booming vaccines business met new challenges in the third quarter, as the company lowered sales forecasts for vaccines for the year.  Notably, quarterly sales of the company’s RSV vaccine, which became a blockbuster after debuting last year, fell by more than 70% year over year, in part due to narrower U.S. recommendations for who should get the shot.

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Novartis gets FDA okay for frontline use of Scemblix in CML

pharmaphorum

Novartis says FDA approval for frontline use of its leukaemia drug Scemblix will boost the number of eligible patients four-fold, as it hunts blockbuster sales

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Baxter exits China IV fluids market amid tough local competition, US shortage

Fierce Pharma

Baxter International plans to exit China’s intravenous fluids market, multiple local media outlets report, citing a letter to distributors. | Baxter plans to exit China's IV fluids market as it faces tough local competition and as it redirects global IV supplies to the U.S. to cope with a post-hurricane shortage.

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Backlash builds against Novo’s Catalent takeover

PharmaVoice

Roche recently joined naysayers who argue the deal threatens competition in the burgeoning weight loss and diabetes drug market.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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AI and trusted data: The key to unlocking faster, more cost-effective drug discovery

pharmaphorum

Discover how GenAI is leveraging AI technology to streamline R&D processes, ensuring trusted data and accelerating drug discovery timelines while reducing costs.

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Amgen reaps Horizon buyout rewards in Q3 as it gears up for key biosim launches

Fierce Pharma

It’s been about one year since Amgen closed its $27.8 billion Horizon Therapeutics buyout and brought the rare disease drug maker’s clutch of approved therapies under its fold. | In the third quarter, the company's overall sales grew 23% year over year and 8% excluding contributions from its Horizon Therapeutics buyout to $8.5 billion.

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UK Chancellor pledges £22bn rise in day-to-day NHS spending

pharmaphorum

The UK's first female Chancellor Rachel Reeves pumps billions into NHS in the first Labour budget in 14 years

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Novel nanoemulsion-based delivery of antimycobacterial drug

European Pharmaceutical Review

A paper has a described the first reported use of nanoemulsions as a novel delivery vehicle for the oral drug bedaquline (BDQ) “with high loading efficiency as a liquid dosage form”, according to the authors. The researchers explained that in recent decades, the industry has placed significant focus on lipid-based nanocarrier formulations for oral drug delivery.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: With $115 million, biotech startup Axonis Therapeutics pivots to burgeoning pain field

STAT

Axonis Therapeutics, a biotech company that has been quietly operating for the last five years, has raised $115 million after retooling its drug pipeline.  The startup announced Wednesday that it closed a Series A round led by Cormorant Asset Management and venBio Partners — its first major financing after subsisting on a string of seed financing deals.

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AZ confirms its China president is under investigation

pharmaphorum

The head of AstraZeneca's Chinese operations, Leon Wang, has been placed under investigation by the authorities in Beijing

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STAT+: Eli Lilly hits rare stumble, as sales and earnings disappoint

STAT

Eli Lilly’s third-quarter sales and earnings were lower than expected, a rare stumble for the company that had consistently reported strong sales and beat earnings forecasts since demand for its blockbuster weight loss and diabetes drugs began booming. The company reported Wednesday overall revenue of $11.4 billion, lower than the $12.2 billion expected from analysts polled by Visible Alpha.

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Bipartisan legislation aims to block Medicare cuts, boost physician pay in 2025

Fierce Healthcare

Physicians and other healthcare practitioners may get a pay boost in 2025 through a bipartisan bill introduced in Congress on Tuesday. | The bill would increase the 2025 Physician Fee Schedule conversion factor by 4.73%, which would wipe out the expected 2.8% cut to the conversion factor and provide an approximately 1.9% inflationary payment increase for 2025.

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STAT+: Wegovy reduces knee pain in osteoarthritis patients with obesity, study finds

STAT

Semaglutide, better known as Ozempic and Wegovy, helped alleviate pain from knee osteoarthritis and improve function in patients with severe obesity, a new study found.  The results of the 68-week trial were published in the New England Journal of Medicine , and could pave the way for a future FDA approval of GLP-1 receptor agonists for the joint-degrading condition.

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Net profit remains elusive as Alignment Healthcare surpasses membership goals again

Fierce Healthcare

Alignment Healthcare raised membership yet again following its third-quarter earnings, but the company is still not profitable. | Alignment Healthcare recorded another quarterly net loss but increased its membership expectations.

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Navigating Cash-Pay Prescriptions at NCPA 2024: A Guide for Pharmacies

Drug Topics

Explore what to look for in a solution to effectively manage cash pricing.

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Biogen and Neomorph enter molecular glue degrader deal

Pharmaceutical Technology

Biogen and Neomorph have partnered to discover and develop molecular glue degraders for treating Alzheimer’s and other rare conditions.

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Navigating the Future: Key Technology Updates Every Community Pharmacist Should Know for 2024

Drug Topics

Timothy Aungst, PharmD, Founder of The Digital Apothecary, discussed advancements in digital health and what to be aware of regarding the future of technology.

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GSK to acquire Chimagen’s CMG1A46 for autoimmune disease

Pharmaceutical Technology

GlaxoSmithKline (GSK) has entered an agreement to acquire Chimagen Biosciences’ CMG1A46 for $300m upfront.

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Risk of Parkinson Disease Increases With Gastrointestinal Mucosal Damage

Drug Topics

Researchers addressed the gut-first hypothesis of Parkinson disease by identifying how mucosal damage impacts risk of development.

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Harnessing AI to future-proof biopharma

pharmaphorum

Discover how leveraging AI can help biopharma companies future-proof their operations and strategies. Learn about innovative AI strategies that can drive success in the biopharma industry.

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For pharma companies, the possibilities of green chemistry are huge

Pharmaceutical Technology

Green chemistry has the potential to revolutionise the pharmaceutical industry.

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FDA decision casts doubts over future of psychedelic treatments

pharmaphorum

The recent FDA decision on the use of MDMA for PTSD treatment has created uncertainty about the future of psychedelic therapy. Learn more about the implications and potential impact on patients.

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UK's Labour Party unveils £520M innovative manufacturing fund as part of life-sci-heavy budget

Fierce Pharma

Biopharma production efforts are set to receive a big boost in the U.K. thanks to a new budget rolled out by the Labour Party following this summer’s general election. | As part of the new budget presented Wednesday by the U.K.’s Chancellor of the Exchequer, Rachel Reeves, the country is debuting a new capital grants vehicle known as the Life Sciences Innovative Manufacturing Fund.

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