Wed.Oct 30, 2024

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Meet the Specialty Pharmacist Championing HIV Care

Drug Topics

Cassandra Esperant, PharmD, AAHIVP, leverages her skills as a clinical pharmacist to champion the health of patients with HIV, both in her clinical practice and through education initiatives.

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Bird flu found in a pig in U.S. for the first time, raising concerns about potential risks to humans

STAT

H5N1 bird flu virus has been found in a pig on a farm in Oregon, the first time the virus has been seen in a pig in the United States, the U.S. Department of Agriculture reported Wednesday. The pig, one of five on the farm, did not display signs of illness. Two others tested negative and testing is ongoing on the other two. All five were euthanized to allow for study of whether the animals were truly infected.

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Sublingual Epinephrine Film Promptly Resolves Symptoms in Patients With Oral Allergy Syndrome

Pharmacy Times

Results indicate that sublingual epinephrine can resolve symptoms, including swelling of the face and throat, associated with oral allergy syndrome in minutes.

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STAT+: AstraZeneca’s China president is under investigation by authorities

STAT

AstraZeneca disclosed Wednesday that Leon Wang , a high-ranking executive who oversees international operations and is also president of its subsidiary in China, is under investigation by Chinese authorities. The company added that it will cooperate, if asked to do so. The move comes after authorities recently detained Eva Yin, a former AstraZeneca executive who is currently chief commercial office for Beigene, a Chinese drugmaker, according to local media reports.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Navigating the Future: Key Technology Updates Every Community Pharmacist Should Know for 2024

Drug Topics

Timothy Aungst, PharmD, Founder of The Digital Apothecary, discussed advancements in digital health and what to be aware of regarding the future of technology.

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STAT+: Novo Nordisk’s Ozempic and Wegovy, long in shortage, are now listed as available by FDA

STAT

All doses of Novo Nordisk’s blockbuster diabetes and obesity treatments are listed as available on the Food and Drug Administration’s drug shortage list as of Wednesday, raising the possibility that the medications could soon be taken off the list entirely, a development that could affect compounding pharmacies and patients relying on compounded drugs.

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STAT+: Early data from Roche’s Alzheimer’s therapy show it’s hitting targets

STAT

An experimental Alzheimer’s therapy from Roche successfully cleared a protein that’s a hallmark of the disease from patients’ brains, the company reported Wednesday, adding to evidence that the drug shows promise. The data are from an early-stage trial and so far Roche has not yet assessed whether there has been any corresponding change in cognitive function or disease progression.

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AstraZeneca's China president faces 'ongoing investigation' by authorities in the country

Fierce Pharma

Following reports of an ex-AstraZeneca executive being detained in China, the company acknowledged that its current president in the country, Leon Wang, "is cooperating with an ongoing investigatio | Following a report of an ex-AstraZeneca executive being detained in China, the company acknowledged that its current president in the country, Leon Wang, "is cooperating with an ongoing investigation.

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National Academies calls to change how biomedical research uses race and ethnicity

STAT

Race and ethnicity are applied in inappropriate and even harmful ways in biomedical research, the National Academies of Science, Engineering, and Medicine said in a report issued Wednesday , calling on scientists, research funders, and publishers to transform the way they use — and don’t use — the categories in research. “The current use of race and ethnicity in research is sometimes seen as an exercise in checking boxes or a matter of using the ‘right’

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Novartis gets FDA okay for frontline use of Scemblix in CML

pharmaphorum

Novartis says FDA approval for frontline use of its leukaemia drug Scemblix will boost the number of eligible patients four-fold, as it hunts blockbuster sales

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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STAT+: Eli Lilly hits rare stumble, as sales and earnings disappoint

STAT

Eli Lilly’s third-quarter sales and earnings were lower than expected, a rare stumble for the company that had consistently reported strong sales and beat earnings forecasts since demand for its blockbuster weight loss and diabetes drugs began booming. The company reported Wednesday overall revenue of $11.4 billion, lower than the $12.2 billion expected from analysts polled by Visible Alpha.

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Dementia With Lewy Bodies Treatment

Med Ed 101

Dementia with Lewy Bodies (DLB) is a type of dementia grouped under the term “Lewy Body Dementia” along with Parkinson Disease with Dementia (PDD)1. The main symptoms of DLB are parkinsonism, REM sleep disorder, visual hallucinations, and changes in cognition2. There are currently no FDA-approved treatments for DLB. However, rivastigmine, an acetylcholinesterase inhibitor, is FDA-approved […] The post Dementia With Lewy Bodies Treatment appeared first on Med Ed 101.

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Opinion: Abortion is just another part of medicine

STAT

This close to Nov. 5, we are being battered with promises that this race will determine the future of the country. But Christine Dehlendorf wants people to remember that as important as Election Day is, it won’t be the end of discussions about reproductive health. “No matter what happens next Tuesday … our friends, our families, our children, [and] next generations to come are going to have to be struggling with whether or not they have the right to make decisions about thei

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UK's Labour Party unveils £520M innovative manufacturing fund as part of life-sci-heavy budget

Fierce Pharma

Biopharma production efforts are set to receive a big boost in the U.K. thanks to a new budget rolled out by the Labour Party following this summer’s general election. | As part of the new budget presented Wednesday by the U.K.’s Chancellor of the Exchequer, Rachel Reeves, the country is debuting a new capital grants vehicle known as the Life Sciences Innovative Manufacturing Fund.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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STAT’s 2024 Diversity and Inclusion Report

STAT

The STAT Diversity and Inclusion Committee presents STAT’s 2024 Diversity and Inclusion Report. Here, we share the self-reported gender and racial/ethnic demographics of our staff from STAT’s inception in 2015 through 2023, as well as our 2023 new hire demographics.  STAT’s Inaugural Diversity and Inclusion Report, published last year, is available here.

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Risk of Parkinson Disease Increases With Gastrointestinal Mucosal Damage

Drug Topics

Researchers addressed the gut-first hypothesis of Parkinson disease by identifying how mucosal damage impacts risk of development.

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STAT+: Sales of GSK’s RSV vaccine down dramatically from last year

STAT

LONDON — GSK’s once booming vaccines business met new challenges in the third quarter, as the company lowered sales forecasts for vaccines for the year.  Notably, quarterly sales of the company’s RSV vaccine, which became a blockbuster after debuting last year, fell by more than 70% year over year, in part due to narrower U.S. recommendations for who should get the shot.

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Eli Lilly's tirzepatide products come up more than $1B short of expectations in Q3

Fierce Pharma

Sales of Eli Lilly’s diabetes and weight loss drugs fell far short of expectations in the third quarter, leading the juggernaut company to reduce its annual revenue guidance and triggering speculat | Sales of Eli Lilly’s diabetes and weight loss drugs fell far short of analyst expectations in the third quarter, leading the juggernaut company to reduce its annual revenue guidance and triggering speculation that skyrocketing demand for the blood sugar modulating treatments has maxed out.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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STAT+: Health tech investments are picking up steam. Here are 5 VC leaders behind the biggest recent deals

STAT

Health tech investments are showing signs of resilience following the perilous lows of 2022 and 2023: Just this past month, two startups that analysts believe might be getting ready for IPOs raised more than $100 million in late-stage funding rounds. And deal volume hit a record high in the second quarter, largely from early-stage deals, according to a Silicon Valley Bank analysis.

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Sage discontinues Zulresso, drops pair of pipeline prospects as it creeps toward 2026 cash cliff

Fierce Pharma

Ever since the FDA rejected zuranolone in major depressive disorder last year, brai | In the wake of a recent round of layoffs, the company this week revealed that it’s discontinuing a commercial medicine and giving up hopes for a pair of pipeline prospects.

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Lilly’s rare stumble, and GSK’s big vaccine miss

STAT

This story first appeared in The Readout newsletter.  Sign up for The Readout  and receive STAT’s award-winning biotech news delivered straight to your inbox.  Good morning. It’s a very busy and spooky Halloween eve today — several companies had big misses in earnings reported this morning. Let’s get into it.

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HIV vaccine candidate successfully optimised for industrial production

Pharmafile

Sumagen Canada Inc, a biotech company based in both South Korea and Canada has partnered with CDMO Naobios to industrialise Sumagen’s human immunodeficiency virus (HIV) -1 vaccine candidate (SAV0001) at bench scale. First of its kind in human vaccine trials, SAV001 is a whole-killed and genetically modified HIV vaccine. During phase 1 of the clinical […] The post HIV vaccine candidate successfully optimised for industrial production appeared first on Pharmafile.

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STAT+: Pharmalittle: We’re reading about disappointing Lilly sales, a Roche Alzheimer’s therapy, and more

STAT

Hello, everyone, and how are you today? We are doing just fine, thank you, especially since the middle of the week is upon us. After all, we have made it this far, so we are determined to hang on for another couple of days. And why not? The alternatives — at least those we can identify — are not so appealing. And what better way to make the time fly than to keep busy.

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Harnessing AI to future-proof biopharma

pharmaphorum

Discover how leveraging AI can help biopharma companies future-proof their operations and strategies. Learn about innovative AI strategies that can drive success in the biopharma industry.

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STAT+: With $115 million, biotech startup Axonis Therapeutics pivots to burgeoning pain field

STAT

Axonis Therapeutics, a biotech company that has been quietly operating for the last five years, has raised $115 million after retooling its drug pipeline.  The startup announced Wednesday that it closed a Series A round led by Cormorant Asset Management and venBio Partners — its first major financing after subsisting on a string of seed financing deals.

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FDA decision casts doubts over future of psychedelic treatments

pharmaphorum

The recent FDA decision on the use of MDMA for PTSD treatment has created uncertainty about the future of psychedelic therapy. Learn more about the implications and potential impact on patients.

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Congressional races to watch, auditory hallucinations, Alzheimer’s drug data

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Hello! Long-time listener, first-time caller. This is Anil Oza, STAT’s Sharon Begley reporting fellow this year. I cover everything from see-through mice to why Bill Nye has rebranded as an activist this year.

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UK Chancellor pledges £22bn rise in day-to-day NHS spending

pharmaphorum

The UK's first female Chancellor Rachel Reeves pumps billions into NHS in the first Labour budget in 14 years

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GSK tries to steady the ship as Arexvy sales plummet in wake of CDC guidance changes

Fierce Pharma

To hear GSK CEO Emma Walmsley tell it, the third quarter presented “some challenges” for the drugmaker. | To hear GSK CEO Emma Walmsley tell it, the third quarter presented “some challenges” for the British drugmaker. For the company’s closely watched respiratory syncytial virus (RSV) vaccine Arexvy, those challenges led to drastically reduced sales.

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STAT+: Wegovy reduces knee pain in osteoarthritis patients with obesity, study finds

STAT

Semaglutide, better known as Ozempic and Wegovy, helped alleviate pain from knee osteoarthritis and improve function in patients with severe obesity, a new study found.  The results of the 68-week trial were published in the New England Journal of Medicine , and could pave the way for a future FDA approval of GLP-1 receptor agonists for the joint-degrading condition.

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Researchers Find “Digital Twin” Model Accurately Predicts Treatment Responses for Different Chemotherapy Drugs

Pharmacy Times

This model, which uses technology that discovers black holes, pulls from real data to evaluate cancer treatments, optimizing treatment choices for patients with different cancers.

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Women with Delayed Menopause May Face Increased Risk of Asthma

Drug Topics

Women experiencing later menopause may face a heightened risk of asthma, underscoring the possible role of estrogen in the development of the condition.

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Humana updates guidance as it beats on revenue, profit in Q3

Fierce Healthcare

Humana updated its outlook for the year thanks to a Q3 where it beat the Street on both earnings and revenue. | Humana updated its outlook for the year thanks to a Q3 where it beat the Street on both earnings and revenue.

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