Tue.Dec 10, 2024

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STAT+: Eli Lilly to test obesity medications as treatments for alcohol and drug addiction, CEO says

STAT

Eli Lilly, the company that makes the blockbuster weight loss treatment Zepbound, will start studying its obesity products as treatments for alcohol and drug abuse, making it the first major drugmaker to do so, CEO David Ricks said Tuesday. Emerging research suggests that GLP-1 drugs — Zepbound is one such treatment — not only reduce food cravings but may also suppress desires for other substances.

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In This Issue: Drug Topics November/December 2024

Drug Topics

See whats trending in pharmacy with a preview of the Drug Topics November/December issue.

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Switching from Trulicity to Ozempic

The Checkup by Singlecare

Trulicity (dulaglutide) and Ozempic (semaglutide) are both brand-name medications approved by the Food and Drug Administration (FDA) to help treat Type 2 diabetes. Because these drugs suppress appetite, some healthcare providers prescribe them off-label for weight loss. However, another medication with the same active ingredient as Ozempic has been FDA approved for weight loss and is sold under the brand name Wegovy.

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New Drug Review: FDA Approves Lazertinib Combination Therapy for Non–Small Cell Lung Cancer

Drug Topics

Study results show improvement in progression-free survival at 22 months.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Pharmacy Leaders Eye Opportunities, Challenges for Legislation in the Year Ahead

Pharmacy Times

The progress made in areas like scope expansion and reimbursement is encouraging, suggesting a growing recognition of pharmacists value within the health care system.

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HIV Treatment, PrEP Have Come a Long Way, With More Work To Be Done | ASHP Midyear

Drug Topics

A tour of modern antiretroviral and pre-exposure prophylaxis therapies included the latest updates in HIV management and prevention.

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More Trending

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Assessing Improvements to Reduce Insulin-Related Hypoglycemic Events | ASHP Midyear

Drug Topics

Medication alerts, nurse education, and pharmacist interventions led to lower hypoglycemic events every year after they were implemented.

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Researchers are betting on cockroaches as the cure to elitism in neuroscience

STAT

Cockroaches are a hardy pest, and often elicit disgust. But they do have a few things going for them: They are cheap, can be raised in a space as small as a shoebox, and aren’t dangerous to humans. That makes the insects uniquely qualified for neuroscience outreach, according to researchers trying to create low-cost tools and free computer programs that can entice students in high school and college to pursue careers in the field.

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DES Model Successfully Simulated MASH Diagnosis | ASHP Midyear

Drug Topics

Researchers observed the use of a discrete event simulation using non-invasive tests for patients with nonalcoholic steatohepatitis.

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PPSV23 Prevents Hospitalization Risk Due to Community-Acquired Pneumonia

Pharmacy Times

The 23-valent pneumococcal polysaccharide vaccine (PPSV23, Pneumovax 23; Merck Sharp & Dohme Corp) demonstrates effective reductions in the risk of hospitalizations.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Understanding Prescription Drug Trends to Encourage Pharmacy Innovation

Drug Topics

Scott Biggs, director of supplier services at IQVIA, discussed pharmacy trends within the industry and how pharmacists can stay ahead of them.

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CD19/CD22-Targeted CAR-T Cell Therapy Achieves Durable Remission in Children With B-ALL

Pharmacy Times

This builds off prior data that showed safety and efficacy of CD19 and CD22 chimeric antigen receptor (CAR)-T cell therapy in children with relapsed or refractory B-lineage acute lymphoblastic leukemia (B-ALL).

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Palliative Care Pharmacist Working to Improve Transitions of Care for Patients

Drug Topics

A conversation with Madison Irwin, PharmD, BCPS, clinical pharmacist specialist in palliative care at University of Michigan Health and a clinical assistant professor at the University of Michigan College of Pharmacy.

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Color blind: Why Portugal has no idea how bad racial disparities are

STAT

LISBON — Across the world, the Covid-19 pandemic laid bare the fact that widespread racial and ethnic inequities often determine whether people can access health care, and who survives. The United States was among nations that saw far higher death rates among its Black and immigrant communities. Was the same true in Portugal? No one knows.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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In A Warming World, Climate-Resilient Health Care Delivery Is Key | ASHP Midyear

Drug Topics

Pharmacists can influence institutional-level climate change-related policies to ensure continued health care delivery.

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Uniqure gets FDA OK to seek accelerated approval

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Good morning. I’m back from my three-week vacation. No big news happened while I was gone, right?

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Examining Remdesivir in Elderly Patients Hospitalized for COVID-19 | ASHP Midyear

Drug Topics

The effectiveness of remdesivir was consistent among patients who received any form of supplemental oxygen and across all age groups in the study.

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What the U.S. can learn from Portugal’s health system

STAT

Get your daily dose of health and medicine every weekday with STAT’s free newsletter Morning Rounds.  Sign up here. Good morning. Let’s get to the news.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Common prednisone side effects in kids

The Checkup by Singlecare

Prednisone is a prescription corticosteroid that decreases inflammation in the body and suppresses the immune system. It is approved by the Food and Drug Administration (FDA) to treat many inflammatory conditions, including rheumatic, dermatologic, gastrointestinal, and respiratory issues. In children, prednisone is primarily prescribed to treat asthma and allergies, as well as a rare disease called nephrotic syndrome (NS) that affects the kidneys.

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How to Use Vitamins and Supplements for Optimal Health

Compounding Pharmacy of America

Learn how to optimize your health with vitamins and supplements. Discover their benefits, how to use them effectively, and tips for personalizing your supplement routine. The post How to Use Vitamins and Supplements for Optimal Health appeared first on Compounding Pharmacy of America.

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How much is Modafinil without insurance?

The Checkup by Singlecare

Modafinil is a central nervous system (CNS) stimulant prescribed for the treatment of narcolepsy and excessive sleepiness related to obstructive sleep apnea and shift work sleep disorder. You may know it by the brand-name Provigil. Like many brand-name drugs, Provigil can be quite expensive, but fortunately, there are a number of ways to save on this treatment.

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ASHP Midyear: Appropriate Use of Broad-Spectrum Antibiotic Can Prevent Antimicrobial Resistance

Pharmacy Times

Pharmacists play a crucial role in promoting the appropriate use of broad-spectrum antibiotics to prevent antimicrobial resistance and improve patient outcomes.

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Is prednisone good for pneumonia?

The Checkup by Singlecare

Prednisone is a corticosteroid prescribed by healthcare providers to treat various medical conditions, such as asthma, allergic reactions, arthritis, inflammatory bowel disease, and adrenal , blood, or bone marrow conditions. It comes in brand-name forms like Deltasone, Prdnicot, PredniSONE Intensol, and Rayos. Prednisone reduces inflammation (redness, heat, pain, swelling), suppresses the immune system, and replaces cortisol.

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Phase 3 POIESIS Trial Explores Safety, Efficacy of Navtemadlin and Ruxolitinib

Pharmacy Times

Navtemadlin has demonstrated meaningful efficacy and safety as a monotherapy or combination treatment in various preclinical and clinical trials.

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Can you take ibuprofen for ear pain?

The Checkup by Singlecare

Ibuprofen is a type of medication called a nonsteroidal anti-inflammatory drug (NSAID). Its sold both over the counter and by prescription. Ibuprofen is approved by the Food and Drug Administration (FDA) to treat inflammatory and rheumatoid disorders. It can be taken by adults, children, and infants 6 months and older to treat numerous conditions and ailments, including mild-to-moderate pain, inflammation, fever, period cramps, headaches, sore throats, and osteoarthritis.

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Research Reveals Opportunities for Antimicrobial Stewardship When Treating Community-Acquired Pneumonia

Pharmacy Times

Results suggest that patients commonly receive more than 5 days of treatment, which could be an opportunity for an antimicrobial stewardship initiative.

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Breo Ellipta alternatives: What can I take instead of Breo Ellipta?

The Checkup by Singlecare

Breo Ellipta is the brand name of an inhaler that contains two medications used to control asthma and COPD ( chronic obstructive pulmonary disease ). This combination inhaler is also available as a generic medicine called fluticasone furoate and vilanterol , which are the names of the two medicines in the inhaler. Fluticasone furoate is a corticosteroid and vilanterol is a long-acting beta agonist ( LABA ).

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IV Form of NAC Receives FDA sNDA to Prevent, Lessen Liver Injury After Ingesting Toxic Quantities of Acetaminophen

Pharmacy Times

Two studies found a 2-bag regimen of N-acetylcysteine (NAC) resulted in fewer and shorter delays in treatment as well as decreases in cutaneous non-allergic anaphylactoid reactions.

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Does Adderall help with OCD?

The Checkup by Singlecare

Persistent thoughts. Repetitive behaviors. Intrusive urges. The signs of obsessive-compulsive disorder (OCD) can be frustrating and anxiety-inducing. It can manifest at any age, and even though approximately 1 in 40 adults will develop OCD at some point in their lives, there are treatment options available. Is Adderall one of them? Its complicated. There are specific cases when it might help, but sometimes it can actually worsen OCD symptoms.

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High-Dose Vitamin D Supplementation Shows Minimal Effect on Type 2 Diabetes Risk in Healthy Older Adults

Pharmacy Times

Further research is needed to identify the influence of high-dose vitamin D supplementation among vitamin Ddeficient populations.

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Seres’ SER-155 gains breakthrough status for BSIs reduction

Pharmaceutical Technology

Seres Therapeutics has received US FDA breakthrough therapy designation for its SER-155, aimed at decreasing BSIs.

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NICE RECOMMENDS LILLY’S TIRZEPATIDE (MOUNJARO ®▼) FOR MANAGING OVERWEIGHT AND OBESITY IN FINAL DRAFT GUIDANCE

Pharmafile

BASINGSTOKE, 5th December 2024 Eli Lilly and Company announced today that the National Institute for Health and Care Excellence (NICE) has published final draft guidance recommending tirzepatide as an option for managing overweight and obesity, alongside a reduced-calorie diet and increased physical activity, in adults with an initial Body Mass Index (BMI) of at […] The post NICE RECOMMENDS LILLYS TIRZEPATIDE (MOUNJARO ) FOR MANAGING OVERWEIGHT AND OBESITY IN FINAL DRAFT GUIDANCE appeared

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ASH 2024: Regeneron’s Ordspono faces challenges, but positive results signal hope

Pharmaceutical Technology

While 88.

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