Mon.Apr 22, 2024

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Scott Soefje, PharmD: Take a Site-Specific Approach to Optimize Care Delivery, Finances

Drug Topics

According to Scott Soefje, PharmD, understanding nuances across sites of care can help health care providers optimize patient care delivery while ensuring financial viability across all settings.

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Optical Sensor Shows Promise in Non-Invasive Continuous Glucose Monitoring

Pharmacy Times

Optical glucose sensing techniques have been reported, but they require complex optical instrumentations found in laboratories, so feasibility for patient use has been challenging.

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STAT+: In a scientific first, researchers use CRISPR base editing to treat liver disease in fetal monkeys

STAT

The ambitious idea of using CRISPR to cure genetic diseases before birth is one step closer to reality. Scientists reported on Monday that they used a form of the technology known as “ base editing ” to alter the DNA of laboratory monkeys in the womb, substantially reducing the levels of a toxic protein that causes a fatal liver disease before the animals had even been born.

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Study Finds Many Individuals With Cardiovascular Disease Consume Twice Daily Recommendation of Sodium

Pharmacy Times

Investigators found that 89% of individuals with cardiovascular disease consumed more than 1500 mg of sodium daily.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Opinion: Free med school tuition won’t solve the shortage of primary care physicians

STAT

Last month, nearly 40,000 medical students were accepted into residency programs on “Match Day.” Surrounded by family and friends, these soon-to-be-physicians opened envelopes revealing where they would begin their careers. This moment marked the culmination of a residency match process that requires medical students to make a series of choices and rankings about which medical specialty to practice and at which health system, along with the various lifestyle factors inherent in suc

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Case Study: Advise Patients on Eligibility, Efficacy of Zoster Vaccine

Pharmacy Times

Sharing data and a personal recommendation can make a difference in a patient’s life

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Counsel Patients About Self-Care Measures, OTC Treatments for Seasonal Allergies

Pharmacy Times

Proper diagnosis and selection of products is crucial to management of hay fever

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STAT+: How a scientific slip-up caused a pregnant woman to get an untested treatment for preterm birth

STAT

Makena, once the only available treatment to prevent preterm birth, has had its share of controversy. A yearslong debate over the drug’s effectiveness led the Food and Drug Administration to withdraw its approval of the product and demand it be pulled from the market after a confirmatory trial couldn’t replicate the results of a key study.

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CMS sets Medicaid payments to home care workers at 80%

Fierce Healthcare

The Centers for Medicare & Medicaid Services is hoping to improve Medicaid enrollees’ access to care through a final rule that better compensates caregiving roles. | CMS released a series of final rules Monday, including Medicaid access regulations that some groups worry will cause providers to close.

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Opinion: An FDA pathway can accelerate innovation for Duchenne muscular dystrophy

STAT

In human biology, the protein dystrophin is a shining example of Joni Mitchell’s classic line, “you don’t know what you’ve got ’til it’s gone.” Dystrophin stabilizes muscle cells. In its absence, the house of cards comes down. For my 6-year-old son, Charlie, dystrophin will govern how long he lives. And how much dystrophin he has in his body depends on the ability of drug developers to continue improving it with innovation.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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Vistagen’s on-demand nasal spray could provide a novel option for social anxiety

PharmaVoice

The fast-acting medication is one of a few new approaches being tested for the crippling condition.

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UnitedHealth ghosts Congress on Change cyberattack — for now

STAT

You’re reading the web version of Health Care Inc.,  STAT’s weekly newsletter following the flow of money in medicine.  Sign up to get it in your inbox every Monday.  Embracing Wall Street, stiff-arming Congress (for now) We finally got an answer of how much financial damage the Change  Healthcare  cyberattack did to UnitedHealth Group: Basically none.

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Simple HealthKit partners with Amazon to increase access to at-home diagnostics and chronic care

Fierce Healthcare

Simple HealthKit is bringing chronic condition diagnostics to front porches across the country via a new partnership with Amazon. | Consumers can now buy Simple HealthKit’s at-home tests for diabetes (HbA1c), respiratory wellness and sexual wellness and have it shipped to their door through Amazon.

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Ocrelizumab Demonstrates Near-Complete Suppression of Relapses for Multiple Sclerosis

Pharmacy Times

Ocrelizumab (Ocrevus; Roche) is being investigated as a twice yearly 10-minute subcutaneous injection compared to the intravenous infusion formulation.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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There's a big market for healthcare data analytics. Here's how Trilliant Health is making moves to stand out

Fierce Healthcare

The $4 trillion healthcare industry is a data-rich sector, and every healthcare player is trying to find a way to use information to drive better decisions, whether in the clinic or the boardroom.< | The $4 trillion healthcare industry is a data-rich sector, and every healthcare player is trying to find a way to use information to drive better decisions, whether in the clinic or the boardroom.

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What pharma stands to gain from technological innovation

pharmaphorum

Pharmaceutical companies stand to gain significant benefits from technological innovation in the form of improved data analytics, streamlined healthcare processes, and enhanced patient outcomes. Explore the potential advantages for the pharma industry.

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UnitedHealth offers update on cyberattack data analysis, systems restoration

Fierce Healthcare

UnitedHealth Group provided an update late Monday on its analysis of the data accessed in the cyberattack on Change Healthcare, and said it identified files that contain personal and health informa | UnitedHealth Group provided an update late Monday on its analysis of the data accessed in the cyberattack on Change Healthcare, and said it identified files that contain personal and health information.

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The Fludarabine Shortage and Its Ripple Effects: Navigating the Crisis

Pharmacy Times

The significant surge in oncology drug shortages in 2023 particularly affected essential chemotherapeutic drugs.

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Headspace expands to direct-to-consumer mental health market

Fierce Healthcare

Headspace has launched direct-to-consumer text-based mental health coaching to expand its reach beyond employer customers and capture the cash-pay healthcare market. | Headspace is entering the direct-to-consumer mental health coaching market, broadening its reach beyond its model of contracting with health plans and employers.

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Therapeutic Relationship Plays Key Role in Psychedelic Treatment

Drug Topics

A higher patient-rated therapeutic alliance was associated with improvements in depression outcomes up to 1 year after treatment.

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US Supreme Court rejects Vanda's bid to revive patents on sleep disorder drug Hetlioz

Fierce Pharma

The prospects for Vanda Pharmaceuticals’ 10-year-old circadian rhythm drug Hetlioz have grown that much dimmer after the U.S. | The prospects for Vanda Pharmaceuticals’ 10-year-old circadian rhythm drug Hetlioz have grown that much dimmer after the U.S. Supreme Court shot down the company’s attempt to challenge an appeals court decision invalidating several of the drug’s patents in 2023.

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Personalized Care, Collaboration Key to Navigating Ethics in Oncology Pharmacy

Drug Topics

Karen Fancher, PharmD, addresses how hearing the perspectives of colleagues can offer invaluable support to shape individualized approaches to ethical dilemmas in oncology pharmacy.

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STAT+: Pharmalittle: We’re reading about an OptumRx contract, 340B dispute resolution, and more

STAT

Good morning, everyone, and welcome to another working week. We hope the weekend respite was invigorating and inspiring, because that oh-too predictable routine of online meetings, phone calls, and deadlines has returned. But what can you do? The world, such as it is, continues to spin. So to give it a nudge in a better direction, we are firing up the coffee kettle to brew some cups of stimulation.

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Ipsen signs $1.8bn RNA drug alliance with Skyhawk

pharmaphorum

Ipsen agrees $1.8 bn alliance with Skyhawk Therapeutics focused on RNA-modulating drugs for rare neurological diseases.

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STAT+: Novo Nordisk’s growth plan

STAT

Want to stay on top of the science and politics driving biotech today?  Sign up  to get our biotech newsletter in your inbox. Morning! Hope you had a delightful weekend. Up today: an exclusive look at the scientific mix-up behind the approval of preterm birth drug Makena. We hear from a mother of a son with Duchenne muscular dystrophy who wants to ensure the FDA’s accelerated approval pathway stays strong, and more.

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AI in Drug Discovery: Day Two

pharmaphorum

Discover the innovative use of artificial intelligence (AI) in drug discovery with a focus on GenAI and Large Language Models (LLMs) on Day Two of this informative event. Explore how technology is revolutionising the pharmaceutical industry.

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Sanofi's Zantac settlement is worth $100M, or $25K per claimant: Bloomberg

Fierce Pharma

Sanofi will pay $100 million—or approximately $25,000 each—to roughly 4,000 claimants who filed lawsuits saying that the French company failed to warn users that its heartburn medicine Zantac (rani | Sanofi will pay approximately $25,000 per person to roughly 4,000 claimants who filed lawsuits saying that the French company failed to warn users that its heartburn medicine Zantac (ranitidine) can cause cancer, Bloomberg reported.

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Jury awards Providence's hourly workers $98M in unpaid wages, though judge could double payout

Fierce Healthcare

A Seattle jury determined that Providence had underpaid thousands of its hourly employees by denying second meal breaks during long shifts and rounding down the minutes they clocked in for a shift. | A verdict reached last week could see up to $220 million paid out to over 33,000 of the system's hourly employees. Providence said it plans to appeal the decision.

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Soon-Shiong's ImmunityBio bags FDA approval for Anktiva to challenge Merck in bladder cancer

Fierce Pharma

After a merger and an FDA rejection, celebrity businessman and biotech entrepreneur Patrick Soon-Shiong’s ImmunityBio has landed the company’s first U.S. | After a merger and an FDA rejection, celebrity businessman and biotech entrepreneur Patrick Soon-Shiong’s ImmunityBio has landed the company’s first U.S. approval in the cancer immunotherapy Anktiva.

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With $75m cash injection, SynOx plans ph3 rare tumour trial

pharmaphorum

Ireland’s SynOx Therapeutics has completed a second-round financing, raising $75 million, as it prepares to take its drug for tenosynovial giant cell tumour (TGCT) into phase 3 trials. TGCT is a rare disease affecting the joints and tendons caused by overproduction of the protein CSF-1, which stimulates the proliferation of various cell types, inflammation, and destruction of the matrix of the joint.

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Pharma Pulse 4/22/24: Will Synthetic, AI-Based Digital Humans Change Pharma and Life Sciences? Climate Change Increases Rate of Infectious Diseases & more

Pharmaceutical Commerce

The latest news for pharma industry insiders.

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BMS preps for CAR-T growth with $380m Cellares deal

pharmaphorum

Bristol-Myers Squibb has shored up manufacturing of its CAR-T therapies by reserving exclusive capacity wt contract manufacturer Cellares in $380m deal

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Health Canada approves Merck’s KEYTRUDA for gastric cancer treatment

Pharmaceutical Technology

Health Canada has approved Merck’s KEYTRUDA (pembrolizumab), an anti-programmed cell death protein 1 (PD-1) therapy for use in combination with fluoropyrimidine- and platinum-containing-chemotherapy as a first-line treatment for adult gastric cancer patients.