Mon.Feb 19, 2024

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Heart Attack Linked With Higher Risk of Other Long-Term Health Conditions

Drug Topics

After myocardial infarction, all-cause mortality was the most frequent event, followed by heart failure, renal failure, and atrial fibrillation.

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SGLT2 Inhibitors Are Underutilized for Inpatient Heart Failure Treatment

Pharmacy Times

Cardioprotective antihyperglycemic agents are underutilized for inpatient care in heart failure patients. Lack of use can lead to preventable patient deaths and hospital readmissions.

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Trending Sources

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‘All of Us’ reports half of the genomes it has sequenced are from non-Europeans

STAT

Six years ago, the National Institutes of Health placed its biggest ever bet on precision medicine, launching a study to enroll over 1 million participants in an ambitious data-gathering gambit unmatched in its scope and diversity. Since then, Americans from all walks of life have been showing up and handing over their blood, spit, and pee to the project, dubbed “All of Us.

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California Passes First-in-Nation Law to Reduce Medication Errors, Address Pharmacy Staffing Concerns

Pharmacy Times

California's Stop Dangerous Pharmacies Act aims to improve patient safety by establishing new pharmacy staffing regulations and a medication error reporting system, arising from understaffed conditions.

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From Diagnosis to Delivery: How AI is Revolutionizing the Patient Experience

Speaker: Simran Kaur, Founder & CEO at Tattva Health Inc.

The healthcare landscape is being revolutionized by AI and cutting-edge digital technologies, reshaping how patients receive care and interact with providers. In this webinar led by Simran Kaur, we will explore how AI-driven solutions are enhancing patient communication, improving care quality, and empowering preventive and predictive medicine. You'll also learn how AI is streamlining healthcare processes, helping providers offer more efficient, personalized care and enabling faster, data-driven

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Niacin has long been a public health darling. But an excess could be bad for the heart, study suggests

STAT

Niacin, or vitamin B3, has long been a U.S. public health darling to the point that it is added, by law, to cereal products. But a new study published Monday in Nature Medicine points to a potentially concerning effect of an excess of the vitamin: It may increase the risk of cardiovascular disease. The study looked into two cohorts of patients without active heart disease, 60% of whom were treated with statins, and found a strong association between a metabolic product of excess niacin and an in

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Full Scope of Pharmacy Practice: Reinventing the Future and Overcoming Barriers

Pharmacy Times

The full scope of pharmacy practice offers a transformative approach to health care delivery, promising improved patient outcomes, greater access to care, and efficient utilization of health care resources.

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More Trending

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Environmental Disinfection Can Be an Affordable, Effective Way to Reduce C Difficile Infections in Hospitals

Pharmacy Times

Targeted use of ultraviolet light and sporicidal treatment can reduce disease transmission alongside existing interventions.

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Roche’s Xolair is first medicine for food allergy in US

pharmaphorum

Fast approaching the end of its patent life, Roche and Novartis’ Xolair is going out with a bang, picking up a new approval as the first and only drug therapy for people with food allergies in the US.

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The Importance of Engaging Stakeholders When Implementing Bispecific Antibodies

Pharmacy Times

Matthew Pianko, MD, outlines the logistical considerations involved when implementing bispecific antibodies for the treatment of multiple myeloma, including the roles of the project champion and other stakeholders as part of a multidisciplinary team.

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Tagrisso-chemo cleared in US as 1st-line lung cancer therapy

pharmaphorum

AstraZeneca’s Tagrisso is cleared by FDA for use alongside chemotherapy as a frontline therapy for EGFR-positive lung cancer (NSCLC)

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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FDA Approves Osimertinib With Chemotherapy for EGFRm NSCLC

Pharmacy Times

Osimertinib was previously approved as a monotherapy, the first-in-line global standard of care, for non–small cell lung cancer indications.

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Transforming clinical data management systems for biotechnology trials

pharmaphorum

Learn how biotechnology trials are transforming clinical data management systems, leveraging machine learning and advanced protocols to enhance efficiency and accuracy in data collection and analysis.

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At risk patients with rare diseases need a higher level of support - and the process must change

Outsourcing Pharma

February will see the 16th annual Rare Disease Day which raises awareness of the more than 7,000 identified rare diseases worldwide.

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Case Study: MGI and Alacris Theranostics

pharmaphorum

This case study explores the collaborative efforts of MGI and Alacris Theranostics in utilising molecular tumour profiling technology for advanced research. Discover the impact of this innovative approach on personalised medicine and treatment strategies.

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What the FDA's New Dosage Guidance Means for the Future of Clinical Research

Speaker: Dr. Ben Locwin - Biopharmaceutical Executive & Healthcare Futurist

What will the future hold for clinical research? A recent draft from the FDA provides valuable insight. In "Optimizing the Dosage of Human Prescription Drugs and Biological Products for the Treatment of Oncologic Diseases," the FDA notes that "targeted therapies demonstrate different dose-response relationships compared to cytotoxic chemotherapy, such that doses below the Maximum Tolerated Dose (MTD) may have similar efficacy to the MTD but with fewer toxicities.

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8 vitamins for depression

The Checkup by Singlecare

Depression is one of the most common mental health conditions. In 2021 alone, 21 million adults —or 8.3% of American adults—experienced a major depressive disorder episode. It is more than just feeling sad; it’s a psychiatric disorder with symptoms that can be severe and can seriously affect your ability to function in daily life, socially, and at work.

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FDA Grants Accelerated Approval to Lifileucel, First-Ever Immunotherapy For Unresectable, Metastatic Melanoma

Drug Topics

The FDA's decision represents a landmark approval of a tumor-derived cellular therapy in a solid tumor cancer.

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Almirall licenses IL-21 antibody from Novo Nordisk

Pharmaceutical Technology

Almirall has signed a licensing agreement for the acquisition of worldwide rights to Novo Nordisk’s IL21-hindering antibody NN-8828.

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WHO initiative to enhance biomanufacturing in LMICs

European Pharmaceutical Review

The World Health Organization (WHO) has launched a new Biomanufacturing Workforce Training Initiative to help overcome challenges within the biomanufacturing sector in low- and middle-income countries’ (LMICs). The programme aims to support the limited capacity within the industry in LMICs. Another goal of the initiative is to manage the shortage of a qualified workforce in the production of biological products, such as vaccines, and monoclonal antibodies (mAbs).

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5 Reasons to Upgrade Your Pharmacy Management Software

Are you still using workarounds to manage your daily operations? To achieve peak performance, it's time to explore other options for specialty and infusion pharmacy software. Streamline pharmacy operations and improve clinical performance with automated processing, real-time data exchange, and electronic decision support. Download this helpful infographic to: Drive efficiency and patient adherence from referral receipt to delivery and ongoing care – all with our Pharmacy Cloud.

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Rybelsus vs. Ozempic: Differences, similarities & side effects

The Checkup by Singlecare

When it comes to treatments for managing blood sugar levels, there are now more options than ever. Rybelsus and Ozempic are brand-name medications used to improve blood sugar in people with Type 2 diabetes. Although they’re not approved by the U.S. Food & Drug Administration (FDA) for weight management, many people find they lose weight with these medications, especially with lifestyle changes like a healthy diet and regular exercise.

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Novel immunotherapy approved for melanoma

European Pharmaceutical Review

Amtagvi (lifileucel) is the first tumour-derived autologous T cell immunotherapy therapy to be approved by the US Food and Drug Administration (FDA) for certain adults with unresectable or metastatic melanoma” Amtagvi (lifileucel) is the first tumour-derived autologous T cell immunotherapy therapy to be approved by the US Food and Drug Administration (FDA) for certain adults with unresectable or metastatic melanoma.

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What causes nausea after eating? Related conditions and treatments

The Checkup by Singlecare

Chances are, you know the feeling. You ate a little too much of something a little too spicy, and now your stomach is upset, you feel a little sick as if you might vomit, and you’re looking for a bathroom. You’ve got nausea after eating, and you’re pretty sure you’re going to have diarrhea, too. It happens to just about everyone from time to time. But what, exactly, causes nausea after eating?

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Initiative by Innovative Trials to boost patient retention inspired by boy's love of collecting

Outsourcing Pharma

The father of a boy diagnosed with acute lymphoblastic leukemia at the age of nine, inspired by his son's love of collecting, has created patches of positivity for children going through cancer treatment to collect.

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10 foods that help with bloating and 8 foods to avoid

The Checkup by Singlecare

Belly bloat has many causes, including excess gas, fluid retention, constipation, menstruation, food intolerances, small intestinal bacterial overgrowth, and irritable bowel syndrome. But whatever the cause, you may be able to prevent bloating by tweaking your diet. We’ve consulted the experts to recommend 10 foods that help with bloating and eight foods to avoid for bloating.

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Promoting Heart Health Awareness During American Heart Month

Pharmacy Times

Pharmacists can raise awareness about heart health during American Heart Month

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AstraZeneca’s Tagrisso gets FDA approval, delaying lung disease progression by nine months

Outsourcing Pharma

Patients in the US with epidermal growth factor receptor mutated (EGFRm) advanced lung cancer can now receive an important new treatment option delaying disease progression by nearly nine additional months.

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Risk adjusted net present value: What is the current valuation of Dyne Therapeutics’s DYNE-251?

Pharmaceutical Technology

DYNE-251 is an antisense oligonucleotide commercialized by Dyne Therapeutics, with a leading Phase II program in Duchenne Muscular Dystrophy.

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In Almost Half of Couples, Both Partners Have Hypertension, Study Results Show

Pharmacy Times

This Valentine’s Day, remind patients to focus on their heart health

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AZ, Daiichi eye December verdict for TROP2 ADC

pharmaphorum

FDA sets December date for decision on AstraZeneca and Daiichi Sankyo’s TROP2-directed ADC Dato-DXd as a therapy for lung cancer (NSCLC)

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Monitoring Treatment, Managing Quality of Life in Patients With ccRCC

Pharmacy Times

The pharmacist’s role may vary across different practices and institutions.

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HP&M Welcomes Senior FDA Official, Ana Loloei, to the Firm

The FDA Law Blog

Hyman, Phelps & McNamara, P.C. (“HP&M”) is pleased to announce that Ana Loloei has joined the firm as Counsel. Ms. Loloei is a 14-year veteran of the FDA, where most recently she served as a Senior Regulatory Counsel in the Office of Policy at CDRH. While at FDA, Ms. Loloei also served as a Senior Policy Advisor in CDRH and as a Special Advisor in the Office of the Commissioner.

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Making “Rheum” for Biosimilars: Overcoming Reluctance

Pharmacy Times

Despite the proven efficacy of biosimilars, both patients and health care providers often have some reluctance when switching from an originator drug to a biosimilar.

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Iovance’s Amtagvi gains FDA accelerated approval for melanoma treatment

Pharmafile

Iovance Biotherapeutics has announced that the US Food and Drug Administration (FDA) has approved Amtagvi (lifileucel) suspension for intravenous infusion for the treatment of adult patients with unresectable or metastatic melanoma, previously treated with a PD-1 blocking antibody and, if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor.

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AAM commends HHS, FTC call for information, solutions on drug shortages

Drug Store News

A Request For Information asks what impact GPOs and drug wholesalers have on generic medication shortages.

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