Sat.Sep 14, 2024

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STAT+: Pfizer drug shows promise in cancer-related condition that causes weight loss and weakness

STAT

BARCELONA, Spain — Patients with advanced cancers often develop a secondary condition that causes them to shed weight, making it even harder to tolerate their cancer treatments. Called cachexia, it’s an under-recognized syndrome that researchers are still trying to tease out, and one that’s attracting more interest from drugmakers.

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ESMO 2024 – Today’s oncological roots are branching

pharmaphorum

ESMO 2024 began on Friday 13th September. Prof Andres Cervantes discussed how building trust has been a several generation development, following five decades of effort in the oncological space.

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STAT+: Incyte’s checkpoint inhibitor staves off disease progression in anal cancer trial

STAT

BARCELONA, Spain — A widely used immunotherapy approach helped stave off disease progression in patients with a type of anal tumor, researchers reported Saturday, potentially setting up the drug for approval in a cancer that’s largely caused by human papillomavirus.  The Phase 3 trial tested the PD-1 targeting antibody retifanlimab in combination with chemotherapy versus chemotherapy alone in patients with recurrent or metastatic squamous cell carcinoma of the anal canal.

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Emerging Frontiers: The Gut Microbiome's Role in Enhancing Cancer Immunotherapy and Treatment Outcomes

Pharmacy Times

An ESMO 2024 presentation explores the growing role of the gut microbiome in immunotherapy response, emerging diagnostic tools such as PCR chips, and innovative therapies such as fecal microbiota transplantation and microbiome-preserving strategies to improve patient outcomes.

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Position Your Pharmacy for Expansion

Speaker: Chris Antypas and Josh Halladay

Access to limited distribution drugs and payer contracts are key to pharmacy expansion. But how do you prepare your operations to take the next step? Meaningful data: Collect and share clinical data regarding outcomes, utilization, and more Reporting: Limited distribution models require efficient tracking and reporting systems Workflows: Align workflows with specific pharma and payer contractual requirements For in-depth, expert insights on pharmacy expansion, watch this webinar from Inovalon.

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ESMO: With survival win, Merck's Keytruda redeems itself in early triple-negative breast cancer

Fierce Pharma

In 2021, the FDA blasted Merck for using a premature endpoint to pursue a Keytruda approval in early-stage triple-negative breast cancer (TNBC). | In 2021, the FDA blasted Merck for using premature data to pursue a Keytruda approval in early-stage triple-negative breast cancer. Now, the PD-1 inhibitor has gold-standard overall survival data to back its case.

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Experts Highlight the Need for Greater Diversity in Dermatological Clinical Research

Pharmacy Times

Not only do diverse clinical cohorts improve the strength of the data, but it improves public trust in clinicians and the medical system as a whole.

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Unveiling the Microbiota's Role in Cancer: From Tumorigenesis to Treatment

Pharmacy Times

The gut and intratumoral microbiota influence cancer development, progression, and treatment responses, highlighting the potential for treatment strategies that leverage these microbial interactions to enhance cancer therapies.

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Now Trending: Updated Colonoscopy Guidelines, Out-of-Pocket Caps for Cancer Patients

Drug Topics

Check out this recap of articles published on our sister sites during the past week.

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ESMO: AstraZeneca's Imfinzi extends life in prostate cancer type. Will FDA push back on its perioperative trial design?

Fierce Pharma

AstraZeneca’s Imfinzi recently became the first PD-1/L1 inhibitor to deliver a patient survival win in muscle-invasive bladder cancer (MIBC). | AstraZeneca’s detailed data show exactly how Imfinzi became the first PD-1/L1 inhibitor to deliver a patient survival win in muscle-invasive bladder cancer. But the win came from a perioperative regimen, a trial design that’s been criticized by the FDA in lung cancer.

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