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First virtual clinical trial examines two promising Alzheimer’s drugs

European Pharmaceutical Review

A new computer model has successfully simulated a clinical trial evaluating the efficacy of aducanumab and donanemab for Alzheimer’s disease (AD), establishing a gradual increase in dosage up to the maximum dose helps to minimise cognitive decline and limit side effects. . We’ve shown that this type of model can work.

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Merck & Co plans to file cough drug gefapixant after phase 3 success

pharmaphorum

Roy Baynes, senior vice president and head of global clinical development, chief medical officer, Merck Research Laboratories, said: “COUGH-1 and COUGH-2 are the first companion Phase 3 trials in refractory or unexplained chronic cough, underscoring Merck’s commitment to fully researching the potential for gefapixant in this patient population.