STAT

JUNE 8, 2023

In a 1975 paper, published in Science , Hayes and his colleagues definitively established that taurine deficiency was to blame for retinal degeneration in cats, a landmark discovery that forever changed feline nutrition and eventually launched the Garfield-endorsed Alpo cat food. Continue to STAT+ to read the full story…

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Immunization 98

Pharmaceutical Technology

APRIL 17, 2023

Merck has signed a definitive agreement to buy clinical-stage biotechnology firm Prometheus Biosciences for $10.8bn, strengthening its immunology pipeline. Prometheus Biosciences uses precision medicine to discover, develop and commercialise new therapeutic and companion diagnostic products to treat immune-mediated diseases.

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Immunization 105

The Checkup by Singlecare

DECEMBER 16, 2022

Lots of good-for-you foods get casually called “superfoods,” but if there’s one that definitely deserves the title, it’s the sweet potato. It’s important to note, though, that the way in which you eat sweet potatoes definitely plays a role here. They’re good for your immune system. They pack a nutritional punch. .

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Immunization 124

pharmaphorum

JANUARY 5, 2023

have announced they have entered into a definitive agreement for Moderna to acquire OriCiro at a cost of $85 million. Biotech Moderna, Inc. and OriCiro Genomics K.K. The deal marks 10-year-old Moderna’s first acquisition.

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Pharmaceutical Technology

SEPTEMBER 8, 2022

Roche has signed a definitive merger agreement for the acquisition of US-based biopharmaceutical company Good Therapeutics for an upfront payment of $250m in cash. Good Therapeutics focuses on the development of PD-1-regulated IL-2 drugs that are based on innovative conditionally active drug technology.

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Immunization 111

Pharmafile

DECEMBER 12, 2023

AstraZeneca has announced that it has entered into a definitive agreement to acquire Icosavax for approximately $15 per share or an approximate total value of $1.1bn.

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Immunization Vaccines 59

pharmaphorum

SEPTEMBER 8, 2021

In a letter to The Daily Telegraph newspaper with AZ’s head of biopharma R&D Mene Pangalos, Soriot write that the UK is only a few weeks away from having a definitive answer on whether two doses of COVID-19 vaccines can provide “continued, protective immunity.”

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STAT

APRIL 5, 2024

If it is true that spring has sprung — and we are still awaiting definitive evidence — you might want to enjoy the great outdoors and watch the trees and flowers slowly come to life. The rotation will likely include this , this , this , this and this. And what about you?

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Vaccines Immunization 105

The Infectious Pharmacist

AUGUST 19, 2021

Anyway, today’s “Booster Doses – Part 1” will go over some of the basics of booster doses and review the use of additional doses (not boosters) in patients with compromised immune systems. At the bottom of each part in this series you will find a link to some background posts that may be helpful, as well as a list of definitions.

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Immunization Vaccines Hospitals FDA 52

pharmaphorum

APRIL 12, 2021

This is the definitive drug development forum for research teams to investigate how to modulate the cGAS-STING and Toll-like receptor (7/8/9) pathways both as monotherapies and as adjuvants in combinatorial approaches. View the full event guide now. The post STING & TLR Targeting Therapies Summit appeared first on.

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Immunization 52

The Checkup by Singlecare

OCTOBER 16, 2023

The SSA offers two types of Social Security disability benefits for those who meet the agency’s strict definition of “disabled.” Immune conditions Immune system diseases cause a problem with the body’s ability to recognize and fight infection properly. Where do you go to start the process? citizen and resident of the U.S.

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Documentation Immunization Mayo Clinic Insurance 105

Pharmaceutical Technology

AUGUST 5, 2022

Gilead Sciences has signed a definitive agreement for the acquisition of the complete outstanding share capital of MiroBio in a deal valued at nearly $405m in cash, subject to necessary adjustments. With the acquisition, Gilead will gain access to the discovery platform and complete line of immune inhibitory receptor agonists of MiroBio.

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Immunization 52

The Infectious Pharmacist

AUGUST 20, 2021

In Booster Doses – Part 1 I wrote about some of the basics of booster doses and the need for “additional” doses (not booster doses) in patients with compromised immune systems. Today I’m going to talk about some of the rationale behind booster doses in patients with healthy immune systems. No, that’s not the case.

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The Checkup by Singlecare

MAY 16, 2024

From a breakthrough drug to standard-of-care treatment, Remicade (infliximab) has a storied history of treating autoimmune disease —when the immune system mistakenly identifies healthy tissues as foreign and initiates an attack. The slight structural differences in biosimilars can mean that they each elicit a distinct immune response.

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pharmaphorum

SEPTEMBER 16, 2020

Regeneron hopes that RECOVERY will provide definitive data about REGN-COV2 and its impact on mortality, hospital stays and the need for ventilation. Regeneron tested thousands of antibodies produced in mice modified to have a human immune system, as well as antibodies identified from people who have recovered from COVID-19.

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The Infectious Pharmacist

AUGUST 21, 2021

Because the booster dose appears to generate such a robust immune response (measured primarily by antibody concentration in the blood) that any differences at that point will be meaningless. Don’t start worrying that your immune system isn’t working; it is. Please see this post to review some basic definitions.

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pharmaphorum

OCTOBER 23, 2020

Anita de Waard from Elsevier and Radoslav Kirkov from Estafet tells us how a hackathon is harnessing data science to look beyond the hype and seek definitive clinical evidence. how long does the immunity from BCG last after that vaccination? Does the strain of BCG vaccination impact immunity? For example.

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Vaccines Immunization Hospitals 110

pharmaphorum

APRIL 16, 2021

The 2 nd Gene Therapy Immunogenicity Summit is the industry’s definitive forum enabling you to better modulate, measure and predict immune response to your gene therapy candidate. Join your peers online and discover: How Chameleon Bioscience are developing an immune evasive AAV for repeat dosing.

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Immunization FDA 52

The Checkup by Singlecare

OCTOBER 14, 2024

In fact, there’s no definite recommended daily limit to the amount of pineapple you can eat. It helps support your immune system and keep your metabolism functioning. For example, B-6 supports a healthy immune system and nervous system, as well as healthy brain development. But that doesn’t mean you need to avoid it altogether.

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Labelling Immunization 105

Pharmaceutical Technology

NOVEMBER 15, 2022

Jnana Therapeutics and Roche have signed a second partnership and licence agreement to discover small-molecule drugs to treat cancer, immune-mediated and neurological ailments. Jnana will conduct discovery and preclinical works against various cancer, immune-mediated and neurological ailment targets.

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Immunization 52

European Pharmaceutical Review

FEBRUARY 15, 2023

One patient experienced a recurrence within the first ten months post-treatment but has since been disease-free after definitive chemoradiation. Only one late-onset immune-related adverse event (AE) occurred, 16 months post-treatment. The one death in this subgroup was unrelated to cancer.

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Chemotherapy Immunization FDA 98

pharmaphorum

NOVEMBER 15, 2021

Arriving at a critical point for TIGIT development, the 2nd Annual TIGIT Therapies Summit is the definitive industry-led event focused on propelling this next-generation inhibitor to clinical use. Plus 2 add on workshops: • Elucidating the anti-tumor immunity of other immune checkpoint inhibitors in oncology.

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Medical Schools Immunization Hospitals 52

The Checkup by Singlecare

AUGUST 19, 2024

This plant compound has been attributed to dozens of health claims , such as protecting against cancer and signs of aging and improving eye, brain, and bone health, though many of these claims are still undergoing research and aren’t definitive. The purple fruit is additionally a good source of immune-supporting vitamin C.

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The Thyroid Pharmacist

JUNE 30, 2023

However, low doses of this medication (hence, low dose naltrexone or LDN), have been found to modulate the immune system and have shown promise in improving cases of autoimmune disease. These include Crohn’s, MS, and Hashimoto’s, as well as other immune system-related conditions such as cancer and HIV/AIDS. Doses of 1.5-4.5

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The FDA Law Blog

JUNE 2, 2023

Most are new or revised definitions and administrative changes, but several proposals represent new policies that should be of concern to drug manufacturers. What is noteworthy about this proposed definition is that it adds a new requirement that “[a] manufacturer must make data available to CMS to support its finding.”

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Labelling Vaccines FDA Immunization 59

The Checkup by Singlecare

MAY 3, 2023

This nutrient also contributes to healthy immune systems, muscle movement, and nerve function. The only definitive way to know vitamin D dietary supplements are working is to have a blood test, says Meredith Warner , MD, an orthopedic surgeon and founder of Well Theory. Vitamin D is essential for keeping bones strong.

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The Checkup by Singlecare

JANUARY 30, 2024

Mast cells are part of the immune system that are present in the skin. When to see your healthcare provider for a stress rash Stress hives and rashes are not necessarily something to worry about immediately, but there are definite times you will want to consult a professional—preferably a dermatologist —for medical advice. “If

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The Checkup by Singlecare

SEPTEMBER 17, 2024

Dupixent works by moderating the immune system—and that can interfere with how your body responds to certain vaccinations. How Dupixent works in the body “People with autoimmune diseases have an immune system that essentially overreacts to certain triggers,” says Jody A. Can you get vaccinated while taking Dupixent?

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pharmaphorum

AUGUST 16, 2022

Following the success of LNP-mRNA vaccines, we have seen an influx of novel types of lipids based nanocarriers over the last 12 months, progress has been made to minimize immuno-toxicity challenges – from maximizing therapeutic window to fine-tuning the immune response. .

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Immunization Vaccines 52

Pharmaceutical Technology

JUNE 24, 2022

invoX Pharma has signed a definitive agreement for the acquisition of all issued and outstanding shares of clinical-stage biopharma firm F-star Therapeutics, in a deal valued at nearly $161m or $7.12 for each share in cash. invoX Pharma is a fully owned Sino Biopharmaceutical subsidiary.

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Immunization 64

Hospital Pharmacy Europe

OCTOBER 2, 2024

The goal for cancer vaccines is straightforward: to harness what has been achieved for infectious diseases and their antigens to focus the immune system on eradicating cancer cells. Moving forward, exploring the factors contributing to variability in patients’ immune responses will be critical.

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Vaccines Immunization Chemotherapy Hospitals 52

Pharmaceutical Technology

MAY 25, 2023

Pyxis Oncology has made a definitive agreement to buy biopharmaceutical company Apexigen, in a deal valued at nearly $16m. Apexigen discovers and develops a new generation of antibody therapeutics to treat cancer, along with new immuno-oncology products to harness the immune system to combat and eradicate cancer.

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Immunization 52

pharmaphorum

AUGUST 23, 2022

With Long COVID, there are a myriad of factors involved, while even the definition of Long COVID is still evolving. Research into coronaviruses has been happening for decades, and this facilitated the development of the vaccines against COVID-19.

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Vaccines Immunization FDA 134

Pharmaceutical Technology

JUNE 19, 2023

Coherus BioSciences has signed a definitive merger agreement to buy clinical-stage immuno-oncology (I-O) company Surface Oncology, in a deal valued at $65m. The company will buy all outstanding Surface Oncology shares at a price of $5.2831 per share, totalling approximately $40m, along with anticipated net cash of between $20 and $25m.

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Immunization FDA 52

Pharmaceutical Technology

MARCH 30, 2023

The combination therapy has also been indicated for patients who do not have EGFR, ALK or ROS1 aberrations and whose tumours are metastatic or locally advanced, and for those who are not candidates for definitive chemoradiation.

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Chemotherapy Immunization FDA 52

Pharmaceutical Technology

DECEMBER 1, 2022

Liminatus Pharma has entered a definitive business combination agreement with special purpose acquisition company (SPAC) Iris Acquisition to create a business with a pro forma enterprise value of nearly $334m. It can induce immune responses against Guanylyl Cyclase C (GCC) expressing colorectal, pancreatic, gastric and oesophageal cancers.

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The Checkup by Singlecare

JULY 10, 2024

It may also boost your immune system, gut health, libido, and overall health. Immune function support There isn’t a lot of evidence of sea moss’ immune system support in human studies, but a 2018 study on Atlantic salmon found that dietary seaweed stimulated the immune response and helped them fight infection.

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