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Trials leave Galapagos’ SIK programme looking under the weather

pharmaphorum

Galapagos has had to send its SIK inhibitor programme back to the drawing board after its lead compound GLPG3970 has failed two of three clinical trials, adding to a string of disappointments for the Belgian biotech. . The preclinical compounds are expected to move into the human testing stage next year.

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Innovation in chemotherapy: Leading companies in platinum-based cancer drug compositions

Pharmaceutical Technology

These compounds cause their therapeutic effect by inhibiting DNA synthesis. The company has filed several patents involving platinum compounds and developed drugs such as cisplatin and carboplatin. Several platinum-based drugs such as cisplatin, carboplatin and oxaliplatin are widely used in cancer therapy.

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7 home remedies for alcohol-induced heartburn

The Checkup by Singlecare

Gingerol , a compound in ginger root, can help to increase gastric motility, thereby reducing symptoms of acid reflux, says Thayer. Ginger Alcohol can slow down gastric motility (the passage of food through the digestive system). That means food sits in your stomach too long, potentially leading to symptoms of reflux, including heartburn.

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Imodium interactions to avoid

The Checkup by Singlecare

Taking multiple medications that prolong the QT interval can compound the risk. One can be born with prolonged QT syndrome, but more commonly, it is acquired by an adverse drug effect. Overdoses of Imodium have been linked to this condition. Accordingly, this must be done carefully or avoided. Check with a doctor before taking Imodium.

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Intelligent Automation in Pharmaceutical Industry (AI & ML)

PharmaShots

Major companies use this approach to find the right compound and check its effects on patients based on biological factors. Automation has deeply influenced the way we earlier saw multifactorial disorders.

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9 foods high in estrogen

The Checkup by Singlecare

Foods high in estrogen Phytoestrogens are estrogen-like plant-based compounds and are the form of dietary estrogen obtained from foods we consume. Biologically active compounds in selected organic and conventionally produced dried fruits , Foods (2020). Mayo Clinic (2023). Red wine and resveratrol: Good for your heart?

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How long after taking ibuprofen can you drink alcohol?

The Checkup by Singlecare

Additionally, NSAIDs (including ibuprofen, aspirin , and naproxen ) may increase your risk of heart attack or stroke, according to the Mayo Clinic—and the risk is higher in people who already have heart disease. Combining these two drugs can compound side effects.