Off-Label Semaglutide Linked to Deaths, Hospitalizations Calling for Compounding Regulation
Pharmacy Times
NOVEMBER 8, 2024
Off-label semaglutide has been linked to serious adverse effects, calling for increased regulation around compounding.
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Compounded semaglutide side effects
The Checkup by Singlecare
FEBRUARY 17, 2025
Many people are turning to compounded versions of semaglutide for various reasons, such as costs and shortages of approved medications like Ozempic and Wegovy. While compounding alternatives might seem appealing, they lack the testing and quality control of their approved counterparts. Is compounded semaglutide safe?
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Paediatric oral compounding: expert insights from a global study
Hospital Pharmacy Europe
JANUARY 16, 2025
A new global study from the International Pharmaceutical Federation (FIP)s Pediatric Formulations Focus Group is the first to report current and global paediatric oral extemporaneous compounding practices. Other reasons for widespread off-label prescribing include the high development cost and complexity in paediatric drug development.
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STAT+: Pharmalittle: We’re watching a ban compounded versions of GLP-1s, a Biogen acquisition, and more
STAT
MAY 22, 2024
A drug often used off-label to treat alcohol use disorder might provide better benefits than therapies approved for this indication, STAT tells us. Australia to ban compounded versions of blockbuster drugs Ozempic and Mounjaro, Reuters reports. If you don’t believe me, just read these items.
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Is compounded semaglutide the same as Ozempic?
The Checkup by Singlecare
DECEMBER 12, 2024
Ozempic is also sometimes prescribed off-label (for a non-FDA-approved use) as a weight loss drug. With the popularity of glucagon-like peptide 1 receptor agonists ( GLP-1 agonists ) like Ozempic, you may have seen advertisements for compounded semaglutide. That includes compounded semaglutide. This is the case with semaglutide.
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The hospital pharmacy landscape in 2024
Hospital Pharmacy Europe
FEBRUARY 8, 2024
Tiene Bauters, PharmD PhD, Pharmacy Department , Ghent University Hospital in Belgium, offers her take on what’s hot on the horizon for hospital pharmacy in 2024. These will undoubtedly present great opportunities for hospital pharmacists and their teams.
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Are compounded GLP-1s safe?
The Checkup by Singlecare
FEBRUARY 14, 2025
As a result, many people look for cheaper options or ways to skip the shortage wait, which is where compounded GLP-1s come in. Compounded drugs are custom-made versions of brand-name medications that are often easier to get and may cost less. Read on to learn more about the safety of compounded GLP-1s and the risks behind using them.
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How cinnamon lowers blood sugar
The Checkup by Singlecare
NOVEMBER 4, 2024
clinical pharmacist at University Hospitals in Cleveland, Ohio, cinnamon may have a modest impact on blood sugar levels. If you prefer to take cinnamon capsules instead of adding ground cinnamon to your foods and drinks, Dr. Sapola says it’s important to read the supplement label so you know how much cinnamon is in each capsule.
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Zepbound vs. compounded tirzepatide
The Checkup by Singlecare
FEBRUARY 13, 2025
When this happens, compounding pharmacies (such as those that work with telehealth companies ) are able to make formulations of a drug that is not readily available. Although compounded versions of tirzepatide, the active ingredient in Zepbound, are becoming popular online, the two drugs are not exactly the same.
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Compounded Mounjaro: Is it safe?
The Checkup by Singlecare
FEBRUARY 13, 2025
It was approved by the Food and Drug Administration (FDA) in 2022 to help control blood sugar levels in adults with Type 2 diabetes , but healthcare providers often prescribe this medicine off-label (for a non-FDA-approved use) for weight loss in people with obesity (or overweight with certain medical conditions). But are these products safe?
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Is compounded semaglutide the same as Wegovy?
The Checkup by Singlecare
FEBRUARY 13, 2025
With the growing popularity of glucagon-like peptide 1 receptor agonists ( GLP-1 receptor agonists ) like Wegovy, you may have seen advertisements for compounded semaglutide productsbut are these products exactly the same as Wegovy? What is compounded semaglutide?
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Adopting Automation Supports Safer, More Efficient Sterile Compounding
Omnicell
SEPTEMBER 5, 2022
Dennis Wright Senior Director, Central Pharmacy Dispensing Services, Omnicell As disruption and uncertainty in the supply of IV medications from outsourced compounding facilities continues, health system pharmacies should reevaluate how they are managing sterile compounding needs. 23 at 1 pm ET.
5 Instances Of Challenging Antibiotic Workflows
IDStewardship
OCTOBER 14, 2024
Read all about this in the product label here. It’s not a fast process and may even require going to another section of the hospital to complete the work. More information on ganciclovir in the label here. Special handling of IV ganciclovir New ganciclovir order at 9 PM is no big deal right? Well, maybe not.
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Gabapentin overdose in dogs: Symptoms and prevention
The Checkup by Singlecare
DECEMBER 30, 2024
If liquid gabapentin is needed, a provider at a compounding pharmacy must prepare it. Additionally, gabapentin is typically used as a human medicine; its prescribed off-label for dogs since it doesnt have FDA approval for them yet. 100 mg compounded liquid or capsule 11-20 lbs. No serious side effects have been noted.
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3D printing and personalised medicines: embracing innovative technologies
Hospital Pharmacy Europe
MARCH 21, 2024
Supporting the successful compounding of drugs with 3D printing processes has the potential to not only fulfil unmet patient needs but also drive efficiencies in hospital pharmacies. 3 But what about 3D drug printing in hospitals? Moreover, hospital pharmacies often encounter challenges related to drug shortages.
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Pharma á la carte – 4/25/23
The Honest Apothecary
APRIL 24, 2023
CALIFORNIA CONSIDERS CLASSIFYING FLAVORING AS “COMPOUNDING “ In a nearly unprecedented move, the state of California is considering treating “flavoring” of a prescription (such as a child’s antibiotic) as “compounding”, thus making the process more difficult and burdensome to pharmacies.
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Reducing Drug Spend with IV Robotic Services
Omnicell
JANUARY 10, 2023
Sterile compounding is also one of the costliest functions in pharmacy operations. Still, many hospital pharmacies continue to struggle to improve safety and efficiency in their sterile compounding operations. Insourcing IV compounding services at Moses H. During this CE-accredited session, scheduled for Tuesday, Oct.
When will Ozempic go generic?
The Checkup by Singlecare
NOVEMBER 13, 2024
It’s also commonly prescribed off-label for weight loss. Some people have tried cheaper alternatives like compounded semaglutide, but these options may not always be safe or trustworthy. These are often sold as compounded drugs containing the same active ingredients as brand-name drugs. Is compounded semaglutide safe?
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Gilead’s COVID-19 drug Veklury falls short in WHO’s global trial
pharmaphorum
OCTOBER 16, 2020
Gilead’s Veklury (remdesivir) has failed to produce an effect on hospital stay and mortality in COVID-19 patients in a large global trial, casting doubt on previous supportive study findings. According to the study the regimens have little or no effect on length of hospital stay or 28-day mortality, the WHO said.
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How Pharmacists Can Use Artificial Intelligence To Advance Their Practice: Insights From ChatGPT
IDStewardship
JUNE 6, 2023
Streamlined Prescription Filling : AI systems can automate prescription filling processes by extracting relevant information from electronic prescriptions, verifying insurance coverage, and generating labels. What are some ways that hospital-based pharmacists can use artificial intelligence to advance their daily practice?
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Can you use metronidazole for cats?
The Checkup by Singlecare
SEPTEMBER 13, 2023
Although not FDA-approved for animals, metronidazole is used off-label in cats when prescribed in veterinary medicine. There’s also a powdered form known as metronidazole benzoate , which is less bitter than the original metronidazole and may be compounded with flavoring to be easier to administer to your cat.
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Can you take ibuprofen with Paxlovid?
The Checkup by Singlecare
AUGUST 15, 2024
This means that the two drug compounds do not negatively impact one another when taken together, regardless of the dose. Food and Drug Administration ( FDA) placed a warning label on the drug. The benefit of Paxlovid is a reduction in the chance that coronavirus symptoms will progress to hospitalization or death.
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How is azithromycin used in cats
The Checkup by Singlecare
MAY 24, 2024
Its use in cats is “off-label,” meaning that the U.S. If a cat has been given too much azithromycin , immediately contact your veterinarian or a veterinary hospital. The American Association of Feline Practitioners (AAFP) and the American Animal Hospital Association (AAHA) consider prevention the best treatment for animal infections.
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Does Zyrtec expire? What you need to know
The Checkup by Singlecare
DECEMBER 2, 2024
Drugs are chemical compounds that can break down over time, and the FDA wants to ensure that consumers are taking safe and effective medication. The expiration date for Zytec is usually two to three years after the manufacturing date, which is also printed on the drug label. Does Zyrtec expire? How long does Zyrtec last?
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The Wholesaling Prohibition (Potentially) Demystified? FDA’s Take on Supply Chains for Section 503B Outsourcing Facilities
The FDA Law Blog
JULY 5, 2023
As a reminder, in Title I of the 2013 Drug Quality and Security Act (DQSA) (the Compounding Quality Act), Congress created the “outsourcing facility” FDA registration category, and set forth statutory parameters for their operation in new section 503B of the FDCA. See 21 U.S.C. 353b(a)(8). 353b(a)(8).
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Ciprofloxacin for dogs
The Checkup by Singlecare
APRIL 19, 2024
Ciprofloxacin is a broad-spectrum antibiotic that veterinarians may use off-label in dogs. If you see signs of an overdose, take the dog to a veterinarian or veterinary hospital. There are no veterinary formulations of ciprofloxacin except those prepared by a compounding pharmacy. Ciprofloxacin is a fluoroquinolone antibiotic.
June is National Safety Month
OctariusRx
JUNE 5, 2023
Use warning labels for both Look-Alike-Sound-Alike and High-Alert medications. If the labels on the shelf are bent, frayed or in any way hard to read, replace them with fresh and clear versions. Compounded Drugs: Will your facility use compounded drugs? According to a 2019 report from the U.S.
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Advocates for Safe IV Preparation Practices Share Their Inspiration Podcast
Omnicell
SEPTEMBER 5, 2022
Mark Neuenschwander Founding Director, THRIVCoalition.org Seminal research from 1997 on IV compounding discovered that 9 percent of manually compounded sterile preparations had incorrect ingredients and/or volumes. All this means hospitals must prepare the majority of their IVs in-house and, we believe this will continue.
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How to get Ozempic prescribed for weight loss
The Checkup by Singlecare
DECEMBER 28, 2023
Weight loss is an off-label , non-FDA-approved use for Ozempic. In some cases, the weight-loss medication offered is neither brand-name Ozempic nor Wegovy but rather a compounded version of semaglutide. The FDA has urged consumers to use caution when taking medication from these compound pharmacies. Here’s what you need to know.
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June is National Safety Month
OctariusRx
JUNE 7, 2022
Use warning labels for both Look-Alike-Sound-Alike and High-Alert medications. If the labels on the shelf are bent, frayed or in any way hard to read, replace them with fresh and clear versions. Compounded Drugs: Will your facility use compounded drugs? According to a 2019 report from the U.S.
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Cephalexin for cats
The Checkup by Singlecare
JULY 20, 2024
Food and Drug Administration has approved it for use in dogs, but cephalexin in cats is considered “off-label.” Cephalexin dosage for cats Cephalexin is used off-label in cats, so dosages might vary. If an overdose is suspected, call a veterinarian or emergency veterinary hospital for advice. In veterinary medicine, the U.S.
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Lisinopril for cats: Uses, dosages, and safety
The Checkup by Singlecare
FEBRUARY 25, 2025
Lisinopril is not FDA approved for use in cats, so veterinarians prescribe lisinopril off-label. Pet owners will have to use tablets made for people or tablets prepared by a compounding pharmacy. A compounding pharmacy or veterinary pharmacy can specially prepare a liquid version of lisinopril made with oil.
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7 health benefits of cinnamon
The Checkup by Singlecare
NOVEMBER 23, 2022
Cassia or Chinese cinnamon: Cassia cinnamon contains coumarin, a compound that can be harmful in large quantities. A few years ago, a viral trend called the “Cinnamon Challenge” caused several people to be hospitalized with lung damage. However, it is also the most expensive.
Confessions of a Nurse Whose Passion for Patient Care Was Supported By Automation
Omnicell
JANUARY 10, 2023
I was first introduced to automated dispensing cabinets for removal of medications when I graduated from nursing school and began working at a hospital in South Carolina. I quickly learned how the automation cabinets provided security and safety for patient care.
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Do You Take Your Pain Medicine for Granted?
The People's Pharmacy
APRIL 10, 2023
Hospitals do.” The reassuring woman tells us that: “Tylenol is the pain reliever that hospitals use most. Each year, Americans make 59,000 emergency room visits for acetaminophen toxicity and there are 38,000 hospitalizations. Surely pharmaceutical researchers should be able to develop newer and safer compounds.
Ozempic Scams: How Counterfeit Drugs Are Fooling Everyone
The Happy PharmD
JANUARY 13, 2025
There are three main types of fake Ozempic making the rounds: complete counterfeits, relabeled insulin pens, and sketchy compounded versions. The relabeled insulin pens are particularly dangerous because if someone whos not diabetic injects insulin, it could land them in the hospital or worse. Pay attention to the details.
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How do you use gabapentin for dogs?
The Checkup by Singlecare
FEBRUARY 8, 2024
For dogs, veterinarians prescribe it off-label to control seizures, manage chronic pain or nerve pain , and control anxiety. Gabapentin is not FDA-approved for use in dogs, so all uses are off-label uses. Gabapentin is prescribed off-label for dogs. If an oral solution is needed, it should be prepared by a compounding pharmacy.
Mirtazapine for dogs: Dosage and safety
The Checkup by Singlecare
MARCH 28, 2024
For this reason, its use in dogs is off-label. So, read labels carefully. Pet parents will use tablets made for humans or mirtazapine custom-made by a compounding pharmacy. If a dog is given too much mirtazapine, call an animal poison control center, talk to the veterinarian, or take the dog to a veterinary hospital.
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What is tramadol used for in dogs?
The Checkup by Singlecare
FEBRUARY 8, 2024
Although it’s approved for use in humans, its veterinary use is off-label , that is, the U.S. These serious adverse effects include: Extreme sedation Agitation Seizures Loss of coordination (ataxia) Call a veterinarian or go to an emergency animal hospital if serious side effects are noticed. Do not use kitchen utensils or tableware.
Rybelsus alternatives: What can I take instead of Rybelsus?
The Checkup by Singlecare
MAY 7, 2024
Keep in mind that while Rybelsus may be used to manage weight loss in people who are overweight or obese, this is considered an off-label use. Other diabetes medications may boost weight loss as an FDA-approved or off-label use. Cinnamon Cinnamon is more than just a spice; it contains compounds that might improve insulin sensitivity.
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Ondansetron for cats: Dosage and safety
The Checkup by Singlecare
AUGUST 15, 2024
Ondansetron for cats is an extra-label use of the drug. In those cases, pet parents can choose between human versions or have the medication custom compounded into a specific dose or flavored oral liquid by a compounding pharmacy. Ondansetron is an anti-nausea drug that veterinarians give to cats for severe nausea and vomiting.
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Why The Pharmacy Profession Wasn’t What I Expected — And How I Adapted Whenever It Got Boring
The Happy PharmD
JUNE 26, 2023
But the courses weren’t geared toward retail pharmacy or even hospital pharmacy. In fact, neither of these pharmacy aspects was introduced until my last year in school when we visited both a retail pharmacy and a hospital pharmacy. Practicing Pharmacy In A Hospital For two years, I worked as a pharmacist in the hospital.
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Amitriptyline for cats
The Checkup by Singlecare
APRIL 19, 2024
Food and Drug Administration (FDA) has not approved the veterinary use of amitriptyline, so all these treatments are considered off-label uses. Urinary bladder inflammation Amitriptyline is commonly used off-label in humans to treat bladder inflammation (interstitial cystitis). Amitriptyline addresses all three.
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Ondansetron for dogs: Dosage and safety
The Checkup by Singlecare
MARCH 25, 2024
Veterinarians commonly use ondansetron for chemotherapy, but its use in dogs is “ off-label.” Still, it hasn’t become a standard extra-label treatment for that condition in veterinary medicine. Take the dog to a veterinarian or animal hospital if the dog starts showing unusual symptoms. Can I give my dog ondansetron every day?
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