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Though some people might be tempted to have a drink at a wedding or during dinner with friends, the medicationlabel clearly advises against it. Combining venlafaxine and alcohol may compound this effect, which may become frustrating and affect relationships. Alcohol can also act as a blood thinner, amplifying the risk.
Diphenhydramine and other CNS drugs Diphenhydramine can have a compounding effect when used with other drugs that have activity within the central nervous system. Antidepressants and anxiety medications can cause some level of CNS depression, and this effect can be compounded with diphenhydramine.
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