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Temperature-stable tuberculosis vaccine induces immune response

European Pharmaceutical Review

Investigators assessed whether administering a temperature-stable vaccine containing both ID93 and GLA-SE in a single vial would be as effective at inducing an immune response as a regimen in which non-thermostable ID93 and liquid GLA-SE are held in two vials and combined prior to injection. However, Sagawa et al. However, Sagawa et al.

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Targeted treatments for childhood febrile illnesses possible with new immune cell insights

Hospital Pharmacy Europe

A study has identified subtle changes in how immune cells respond to different severe febrile illnesses in children, which could lead to improved treatments. In the clinic currently, our treatments for dysfunctional immunity are poor and not targeted to individual children.

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Grace’s 3 Years as an NF2 BioSolutions UK PhD Student

NF2 BioSolutions

I have enjoyed every moment, and I have made the most of all the opportunities to pass my way through the University of Manchester, NF2 research community and the Charity, all of whom have driven this research forward. Although VS and meningioma are both brain tumours in NF2, their immune cells act differently. So what have we found?

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Adam’s 3 Years as an NF2 BioSolutions PhD Student

NF2 BioSolutions

As some of you may know, the focus of my PhD was to explore role of the immune system in VS, particularly a subset of immune cells known as T-cells. Along with PD-1, these T-cells expressed several other inhibitory molecules, all of which are targetable with immunotherapy-based drugs, like immune checkpoint blockade.

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Science Summarised: NF2 and Sporadic Vestibular Schwannoma

NF2 BioSolutions

[Image Description] Paper header for paper titled “The comparable tumour microenvironment in sporadic and NF2-related schwannomatosis vestibular schwannoma” by Gregory et al 2023, published in Brain Communications. Usually, immune cells function to protect the body by clearing infections and abnormal cells (like tumour cells).

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Paving the way for anti-Abeta active immunotherapy

European Pharmaceutical Review

The vaccination of patients with AN1792 led to the activation of their immune systems, which started producing endogenous anti-Abeta antibodies. Therefore, active immunotherapy to trigger the immune system to produce sustained levels of endogenous antibodies has now become far more attractive.

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Provention’s Tzield can delay type 1 diabetes. But will it reach all patients?

Pharmaceutical Technology

These therapies work by reprogramming the immune system, preventing it from attacking and eradicating insulin-producing cells in the pancreas. Although T1D can present in younger children and older adults, the FDA notes that the most common age of onset is between ages four and 14. Equity in early-stage testing.