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FDA drug dosage optimisation guidelines signal clinical trial reform

Pharmaceutical Technology

In January, amidst calls to improve patient safety by optimizing licensed drug formulations, the FDA released a draft guidance that signalled a departure from the most commonly used method of identifying a new therapy’s ideal dosage. The focus on identifying the ideal drug dosage is not new. What is drug dose optimisation?

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Ondansetron for cats: Dosage and safety

The Checkup by Singlecare

Communication between the brain’s nausea center and the gastrointestinal tract is blocked, so the brain can’t activate the vomiting reflex. The degree of liver impairment requiring a dosage adjustment in cats has not been specified in veterinary medicine. Ondansetron dosage for cats Ondansetron dosages can vary.

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Cymbalta generic availability, cost, and dosage

The Checkup by Singlecare

Communicate any concerns or questions about the switch to your healthcare provider, as they can offer personalized advice based on your medical history and overall needs. The post Cymbalta generic availability, cost, and dosage appeared first on The Checkup.

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Prednisone anxiety: Why it happens and how to cope

The Checkup by Singlecare

Natural remedies for anxiety Dr. Kim recommends communicating your side effects closely with your healthcare provider. Dosage adjustments High or prolonged doses of prednisone are more likely than low doses to cause side effects such as anxiety, mood swings, and other mood changes. In such cases, a dose adjustment might be appropriate.

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Is famotidine safe during pregnancy?

The Checkup by Singlecare

Even though famotidine has not been tested in humans, experience and many retrospective studies have shown when used appropriately and in recommended dosages, it is safe in pregnancy,” says Los Angeles-based OB-GYN and urogynecologist Michael Tahery, MD. Also, animal studies have not shown any fetal side effects in pregnant animals.”

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The key role of GMP analytical testing for drug products

European Pharmaceutical Review

Any misalignment in these processes can lead to inconsistencies, making it crucial to follow ICH Q2(R2) guidelines and maintain clear communication between teams. For solid dosage forms, including capsules, tablets, or film-coated tablets, dissolution tests are conducted. Any variations over time must be addressed.

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Connecting with Patients at Home

Pharmacy Is Right For Me

It also improves care coordination and eliminates communication gaps. It involves the training of community paramedics in performing some aspects of medication reconciliation. Any medication changes found during these reviews are communicated to the PCP and community pharmacist. What led you to this career path?

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